5AQLB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
113
structure length
113
Chain Sequence
LGSNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 45
structure length 113
sequence length 113
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqlB00
5AQUB 4HWHA 5AQOB 5AQQB 4HWIB 3FZHB 5AQIB 1HX1B 5AQNB 3FZKB 5AQTB 4HWDA 5AQGB 1T7SA 3FZLB 5AQJB 5AQLB 3M3ZB 1UK5A 3A8YC 3FZFB 1UGOA 5AQPB 5AQMB 4HWCA 5AQRB 5AQHB 5AQSB 1M7KA 1I6ZA 5AQFB 3LDQB 5AQVB 5AQKB 4HWFA 3FZMB 1M62A 2D9DA
chains in the Genus database with same CATH superfamily
2MPKA 2V5DA 3IA3A 2LT3A 3NRYA 2VQET 4JBWF 3M3ZB 4I4TE 4I55E 4DR7T 1T98A 4DR1T 3FBLA 4OK0A 4DV5T 3UUXB 4CXWA 1E1HB 4BA9A 2Q9QA 2XAJB 4X66T 3N9LA 2V1DB 4B6XA 4LMLA 4DR3T 4PK6A 2E9XC 4NUVA 5HEUA 3WI3A 5LMNT 2MYSA 4CI2B 3RYFE 5HXCA 3I0QA 1N36T 3KDSE 4C90A 4I0UA 5FKYA 3ZT7A 2M6IA 3PUAA 1J1JA 2RA1A 5JDMA 4X20E 3O1HA 4A56A 3BK9A 3TLSA 4HKAA 4ZI2D 2W0GA 4AXPA 1KNPA 3KV4A 3ZMUB 1US7B 3RIAA 1W9RA 4K0KT 5L3FB 3VKGA 4PK5A 1MMNA 4WYVA 4NPPA 4L0RA 5FNVE 2WMOA 1T7SA 2MOZA 3ESLA 2N1GA 3PUSA 1UK5A 4ZI3C 3K3OA 4UF0A 5J0ZA 3RYCE 4KX6A 1VCTA 3DJBA 2OLTA 2WY2A 1AJ3A 3LG7A 3OJAA 1D0XA 3FBZA 1KF6A 5HCJA 3IEEA 3RYIE 5DQVA 3EABA 2ZM0A 3ZEFB 4AKLA 4LF5T 1UURA 1FMVA 3PUGA 4HFVA 3RPUA 2X9YA 4WBNE 3KFWX 4YJ2E 5JDFA 1Z0PA 5FY7A 2JMHA 4B3MT 2PTFA 2XQAA 4AKRB 4HEAA 1HF8A 4LMKA 3ETVA 3ZCJA 2IHR1 5LOVE 4LFBT 4I50E 3WAJA 4IDQA 4KBMB 3UQ7A 4J2CA 2LLYA 2ES0A 1D1CA 5CA0E 2V8SV 3ZMVB 2DWGA 5KXJA 2LSJA 3SRZA 2MBGA 2BKNA 4QX8B 4O2AE 3CWZB 2SPCA 4MFRA 2VKOA 4L5GA 2VVNA 4OYKA 1BR4A 1QSDA 3EHZA 4AQYT 3RHWA 1ZOYA 3L09A 1L0VA 4EXTA 5DABA 2WCAA 1NENA 4JI1T 5KDMC 2OA5A 2BG9E 2V5CA 1MMAA 2J4GA 2V6YB 2GK9A 4HFDA 2ZM2A 3JC6D 2KLQA 1NWMX 3ZMZB 3O4XE 3OYXA 3CMLA 2XM1A 2WM9A 2XASB 3HKBE 1OEDA 1UGOA 4NXMT 2WB5A 3ZJ2A 4JYAT 3OYZA 4IDPA 2NTXA 5JVDE 2E5VA 2UXXB 4ZI2C 4AKHA 2M6BA 2ACZA 3ZYLA 1MIYA 3AE8A 4NXNT 3F31A 4JI4T 4EYUA 3H37A 4LF6T 3RIUA 4EEDA 4H9QC 2KWHA 2PFVA 3T1YT 2I59A 5LG3A 4HWIB 2KZ7B 5F8PA 3EVYA 4EOZB 5L4EA 2UXBT 3Q9DA 3UFEA 3N9MA 2BDEA 4LF9T 2WP9A 3TKLB 5L3CB 3GA8A 4DV6T 5LB7B 3P4RA 4JI3T 4IDZA 2LRKA 5FXXA 2VURA 4QWNB 4B3TT 5AQQB 2CXLA 2CM0A 4XAXB 3AVRA 3R84B 3AA7B 2HPJA 1XWMA 1O3XA 3VHLA 1X79A 1OWAA 5JR9A 4JI8T 2W62A 3N9NA 4HWCA 2HN1A 4EZ4A 1HCIA 3LBXB 4DVDA 4IIJE 2LKHA 2WAUA 2QA7A 4B3ST 2A9UA 5LMUT 2WQYA 3PDYA 5C2TA 5HEJA 4X1YE 4IE5A 2X9HA 4X1KE 2UXCT 2V7MA 2BG9C 2VQFT 4DR5T 2CXDA 2QYWA 2Y8DA 3ZCIA 4WZXA 4H9NC 1HX8A 1LVKA 4EZHA 3IHRA 1HNZT 4WBOA 2WSSV 4HGAA 5JDGA 3I9WA 2QRXA 3CPZA 1BR0A 3ZT5A 3C4XA 2VWAA 4Z91A 4TZ4C 2K5BB 5HXEA 5AQFB 3T8OA 3N5LA 1KNRA 4KP3C 2DLRA 3VU7H 2YN6A 2WWVA 2DL1A 4OFZA 3K1SA 3NZPA 3UU3A 2VKHA 1KEYA 5FL0A 5LGTB 1EZ3A 3OPCA 4PJNA 2RPAA 4AKGA 3VKHA 1BR1A 4QHOA 3AAIA 3MZKB 3RIFA 4DUYT 5JRCA 4CQIA 4ISTA 3JC6C 3ZYMA 4HWHA 2IC9A 4EYYR 3FZHB 2LHRA 2UUAT 5H6QB 4X64T 3CVRA 3QB5A 3ONLC 3U3IA 2UXNB 5AQLB 5FVLA 5FXZA 3T1HT 1U5PA 5L3EB 5C3JA 5J2UE 4IL9A 4DMVA 1SHZC 4GIWA 4UVAB 2DHRA 3UQ4A 2HPLA 1IZNB 4HTEA 4U72A 2XQ4A 2CRBA 2XQ9A 3C50A 5ADXL 5HXHA 4PNIA 3CX8B 2CE7A 5JDQA 4CN1A 1M62A 5EZYE 3X1DA 3SOLA 1HFAA 4CI1B 2Y6XA 4CXXA 1VOMA 4A5XA 3RRCA 4IHJE 1OEDC 1D0YA 3P50A 4UELA 4PW8A 3KV9A 2LM9A 2N9DA 3O1IA 3PV0F 2X0YA 5F5WA 4LF7T 4L9IA 4O8SA 5IHYA 4U2ZA 2UXDT 3UULA 2BZBA 2XQYA 4U7IA 3RIUC 4IGUA 4YSZA 2XQ6A 3J7Yq 3ANWA 3UU4A 4ZOLE 2Q9QB 3P4SA 2CHNA 3SS1A 4HWDA 4N78D 3AEBA 2IW5B 5BR8T 1GQEA 3NBXX 1BR2A 5HWYA 2YU1A 2X51A 1QLBA 1S35A 4H9PC 5JDHA 3KVBA 4V1Av 3SFEA 5JR9C 3NWIA 4EEBA 3MXZA 5LCYA 2L3LA 2WWUA 5ETWA 5HXRA 3CIRA 2EHOD 5LJNA 2DNXA 2Y48B 1JNRA 2D9DA 1X9BA 3ONXA 4G2AA 3UTKA 3LK2B 4M1PA 4YT0A 4WW0A 5AQTB 2W67A 3UU5A 3RH3A 4CN4A 1HG2A 3ZPOA 2PJQA 3A8YC 2L8KA 3AE2A 2UU9T 5LP6E 4ANJA 4DR4T 1MIVA 3PUWF 3RC8A 3TLWA 4UVCB 3RX6A 5L4HA 2XTLA 4C91A 4GK5E 3C4ZA 2H7OA 3W15B 4DV2T 2NW9A 4TUYE 3MJXA 3AE7A 2ODUA 1YXRA 5F3JA 2H88A 2WU2A 2BG9A 4YY3T 1IAPA 3NZQA 2YDSA 4DV3T 4G63A 2LSKA 2CHOA 2CA5A 4TNVA 5AQRB 1B7TA 5L3GB 1QUUA 4TWDA 2KSRA 3CQXC 4E7SA 2J1DG 2CWOA 4H9SE 2I6HA 2V7KA 5LJMA 3KINB 5FXVA 2C5KT 4KI0F 3DP7A 4YXDA 4X5TA 3L8RA 3ZC0A 1V9DA 2CLYC 3AE1A 3H3MA 3BQLA 4Q25A 5DQWA 1E7PA 1WFDA 3PE0A 2XQ7A 2ZLYA 3N2GE 2IUBA 4BJNA 1WCRA 4U31A 3AAEB 5HEGA 1N34T 3IBPA 1OXZA 4U3CA 1Y01A 3JAFA 4GOUA 1E2AA 4DV0T 1J5WA 5JTGA 1UX4A 3LK3B 2CEAA 1IBLT 5J1GA 4HFIA 3HA4A 1MIWA 2KINB 4H63H 2FJDA 2A3DA 3PUQA 3RQWA 3UUBA 5TAOA 4DIDB 1KFYA 4JEUB 4MLKA 3FXDB 1XNRT 3RQUA 5L47A 4JI6T 1WYBA 3MKDA 2YEVC 5FYMA 3BQKA 1WR6A 3K3NA 1YQ4A 2QGSA 3PTRB 1NEKA 4CI3B 4EGWA 2CBJA 2JMKA 2P9BA 3UT5E 3C98B 2EHOC 4LF8T 2FBWA 3OVUA 3C51A 3IF8B 3L3PA 5IWAT 2X67A 2E8IA 5AQVB 5M4YA 4EIWA 4OX9T 3ZKRA 2D2SA 2IMLA 4UV9B 3SWHA 2V6YA 5HCMA 4OYJA 4JI5T 4X1IE 4ASKA 2BS2A 4QXCB 3JAEA 5EK3A 4JI2T 3TLVA 1Y64B 4UXNB 5J2TE 3P7IA 5HEHA 2XJ7A 2D0TA 2X0LB 3KV6A 2YDQA 5FP3A 2CXFA 3CX7B 4UV8B 2BS3A 3FXEB 2JRKA 2K48A 5FVKA 3N2OA 5BMVE 2K3WA 2C5IT 2E5LT 3N2KE 1HR0T 2E9XB 1XMQT 4IL4A 2CMRA 2KNDA 2YK0A 1IBMT 5LG4A 2XUEA 5KX5E 1SE7A 1D0ZA 1KK7A 2BVLA 2H3RA 4IE6A 3AE5A 2DI4A 4X65T 4GYRA 5AFUL 4ZHQE 4DR2T 3ZC1A 2V7JA 4JUYA 5AQKB 3CX6B 3B57A 2J62A 3AECA 3EDVA 4IE7A 4XZCA 3AXJA 2FJBA 1VRBA 4O4JE 1CUNA 4P0BA 3GWHA 5AQHB 4EV6A 2K24A 4TX5A 2XAGB 3E0ZA 3EI0A 4HFBA 3JCFA 4KHPT 3LBXA 2XQ3A 4ADZA 1HS7A 2XHEB 5JDLA 3VR8A 4F8HA 1SUMB 3EAMA 4X62T 4YTNA 4KHZF 5JH7E 1YW0A 3MA9A 3ETUA 2E9XD 2XY8B 3AEFA 3AEEA 1T72A 2WMNA 4DV7T 3K3QC 4HN9A 4DO0A 1UUSA 2NW7A 2BKOA 4AISA 4HFEA 4CN6A 1M7KA 4BJMA 3M65A 2XSBA 3KVAA 4NIQA 3HKDE 3AEDA 1G8XA 1MNDA 4PK4A 3I9YA 5ABGA 4DR6T 5LXTE 1I6ZA 4AKIA 4PJMA 2BVMA 1WLXA 2NTYA 3SFDA 4ZZBA 4QX7B 3A5XA 3NVOA 2B76A 2LKGA 2NR4A 4JLEA 5FMNA 2IC6A 3ZJ1A 4Z8XA 3AVSA 5L2LA 2JQ9A 2NP9A 5AQUB 3ZYKA 3GN5A 5AQGB 4JI0T 3NKZA 4QXHB 2IIUA 3TLUA 4CXYA 4EB6E 2X9WA 5EK2A 4AIUA 4QH5A 2C0SA 2AXDS 5HXSA 4P1NA 3HKCE 5E0OA 3S4UA 4YFSA 4FI5A 3UUMA 4GYSA 2W2UA 5IYZE 4E7ZA 2YKSA 2M67A 4HFHA 3PUVF 5JQGE 2VK9A 2HN2A 4YSYA 4ZI7E 2WZIA 3ANWB 2J47A 1FEWA 4ILBA 3VR9A 2EHOA 3HL6A 4DV1T 2FUPA 2YOEA 1FJGT 5LBQB 3ABVA 3QK6A 5ABFA 2MAWA 2ZM8A 2LHNA 4DBQA 1WRDA 4PFPA 4U7YA 3B13A 4AQGA 4TV8E 3RLFF 1MMGA 3PJAA 2JJ9A 2PBIA 4GKKT 1MNEA 4HWFA 2YU2A 4UVBB 2UUCT 3AA1B 1ZP0A 3MK7C 2X66A 3UU8A 2ODVA 3FZKB 1FIOA 5CB4E 2VASA 2A2FX 3AE3A 4DBRA 1W09A 3AAAB 1XDPA 3ZMTB 3V5UA 2CBIA 2HH7A 3V5SA 2BBJA 5LHHB 2NOXA 1XZYA 1I94T 4CZZB 2X0HA 5LGNB 1H7CA 5LNKA 2B1EA 2X68A 1LKXA 4ZZCA 4GK0E 2LSGA 2VL8A 3N9PA 3QOFA 3RC3A 1UCUA 3KV5A 3O1JA 2KT9A 5ABHA 2WDVA 2NWBA 5FL1A 4F6RC 3Q2MA 2XAFB 3P8CD 3EUHA 4UF0B 5JDNA 3FZLB 2W63A 3D0TA 3E08A 2LEHA 2Q9QD 3ZN0B 4MHCA 2BG9B 2RP4A 1WR0A 1ZKEA 4UEMA 1ZHCA 2R6GF 2VB6A 1YD8G 3RYHE 4BAYB 3OTOT 2G0UA 2X9XA 1ZV4X 2K9AA 4U33A 5FY1A 1LRZA 3AE6A 2XAHB 3DTOA 4P0AA 5C8YE 1VCSA 1HG5A 4O4HE 2OV9A 3FZMB 4QH1A 1Z8UA 3QB5K 1S94A 4YHJA 1R8IA 3AEAA 4O4LE 5IUXA 5AQJB 2CWYA 4YTMA 4ZXLA 4TV9E 1N33T 3PUXF 4JEHB 3N9QA 2W4XA 3F2EA 3JADA 2D5UA 3WAKA 2KMFA 4YJ3E 2XZEA 3PU3A 2KWIB 4P09A 3AE4A 2L9QA 5LYJE 3FZFB 3OKQA 1T8BA 3RI5A 2HHHT 4IE4A 3OBVE 1W0BA 4KMCA 5DJQC 2IAKA 2NW8A 3ZLIA 3LJCA 4YHHT 3Q5EA 5CGMA 2W66A 4A98A 5HAXA 2FJAA 2XAQB 1IBKT 5FY0A 3P4WA 4YLHA 2JQKA 3AE9A 2LE8A 2JPFA 4Z90A 5LHGB 1HNWT 2QVAA 4QXBB 3RKGA 3I1AA 4ZS2A 4TWFA 2N2NA 3PUZF 2PG8A 5ABEA 2ZM6T 5LA6E 1WYCA 3VRBA 5HYAA 5HWXA 5FXWA 3RKOA 4AQFA 1ZEEA 1SA0E 4GKJT 1OEDB 3Q5XA 2JIWA 1XDOA 4IDNA 1MMDA 3CQCB 3FB2A 4H63V 4UIGA 3GMIA 1HNXT 4KUMB 4PAGA 3KBTA 2KXPB 2Z6EA 3ZSTA 3QNUA 2CCQA 1FMWA 2BS4A 4H9OC 4K0UA 4B3RT 1HTJF 3C4WA 2V7IA 5CA1E 1XMOT 3Q5WA 2W61A 2FJEA 2Q9QC 4ILUA 3HKEE 3AB3B 3PURA 4FJOA 4NUUA 3LK42 4LFCT 3PJAJ 3P4QA 3CQGB 2V7LA 5JREA 4O2BE 1YKEB 3LFMA 3AEGA 4DV4T 5L3BB 1J5ET 2A72A 3L39A 4LMJA 3NRXA 2VKJA 3TLTA 3PU8A 2MTQA 5JR9B 5LHIB 3G06A 1NAFA 2WDRA 4DMWA 1IJ5A 2W00A 4ILCA 3UUNA 3ZN1B 4PJLA 2XPKA 5AQMB 2V26A 2AE9A 4ISSA 2LOPA 3AXJB 2E9XA 5AQOB 5L3DB 4LF4T 3CKDA 4OHFA 2IDOB 3ONJA 4WNKA 4U2YA 3EDUA 2LSIA 4DNDA 4COFA 5CFBA 2DWKA 3F57A 4TNWA 4HE8A 4O4IE 3HI2A 2ACXA 2H89A 4ZS3A 3ZSSA 3UFGA 5AQNB 3CK6A 4IT4A 2D0UA 2F4VT 2C5JA 2H7VC 1D1AA 2JQHA 4MBQA 5A1LA 1D1BA 3O9XA 4LFAT 1YQ3A 3ZT6A 3AA6B 4IE0A 3U78A 1OEDE 2YINA 1XNQT 3H3AA 5LBMA 2LM2A 2BBHA 2XQ8A 2XQ5A 2V6XA 1JNZA 4YTPA 2WS3A 3Q5DA 3LSVA 4DUZT 2XM2A 2WU5A 2WDQA 4U74A 2CPTA 5JRCB 5AQIB 3A7MA 3C64A 3I0OA 3QUJA 3J9X1 3RGLA 4TN7B 3E22E 4IDOA 5AQSB 2E2AA 3HR0A 3P4PA 4PJJA 1W0AA 1IJ6A 3QC9A 2CLYB 4ERRA 4ZEYA 2I0MA 4ILAA 2VVSA 3K8PC 1UX5A 5CJ5A 4QH4A 2XSAA 3MACA 3N9OA 3UU6A 3R6NA 4AI6A 3GN5B 3BQIA 4ZI3D 1LVFA 2YDRA 1HX1B 3AA0B 5HEOA 4I43B 3RRWA 4QKNA 3LDQB 4MALA 4JV5T 1U4QA 1CHUA 3ZMSB 2ZMAA 1DU2A 4AQFC 3PUYF 4TWHA 1KNZA 2VKDA 3VRAA 2WBLA 4UR9A 4HFCA 4H9RC 2UUBT 4EAHA 5GONE 4XBFB 1YKHB 2DCFA 5EK4A 5H6RB 2BKPA 3B5MA 2WZHA 5KMGP 2LOSA 2JQQA 3RF1A 2EHOB 4YSXA 1G73A 2LRLA 3KBUA 2LJLA 2VL0A 1N32T 5AQPB 5ABFB 2LSYA 4A97A 4JI7T 4IREA 5LGUB 4PFOA 3FHNA
chains in the Genus database with same CATH topology
5AQUB 4HWHA 5AQOB 5AQQB 4HWIB 3FZHB 5AQIB 1HX1B 5AQNB 3FZKB 5AQTB 4HWDA 5AQGB 1T7SA 3FZLB 5AQJB 5AQLB 3M3ZB 1UK5A 3A8YC 3FZFB 1UGOA 5AQPB 5AQMB 4HWCA 5AQRB 5AQHB 5AQSB 1M7KA 1I6ZA 5AQFB 3LDQB 5AQVB 5AQKB 4HWFA 3FZMB 1M62A 2D9DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AQU B;  4HWH A;  5AQO B;  5AQQ B;  4HWI B;  3FZH B;  5AQI B;  1HX1 B;  5AQN B;  3FZK B;  5AQT B;  4HWD A;  5AQG B;  1T7S A;  3FZL B;  5AQJ B;  5AQL B;  3M3Z B;  1UK5 A;  3A8Y C;  3FZF B;  1UGO A;  5AQP B;  5AQM B;  4HWC A;  5AQR B;  5AQH B;  5AQS B;  1M7K A;  1I6Z A;  5AQF B;  3LDQ B;  5AQV B;  5AQK B;  4HWF A;  3FZM B;  1M62 A;  2D9D A; 
#chains in the Genus database with same CATH topology
 2MPK A;  2V5D A;  3IA3 A;  2LT3 A;  3NRY A;  2VQE T;  4JBW F;  3M3Z B;  4I4T E;  4I55 E;  4DR7 T;  1T98 A;  4DR1 T;  3FBL A;  4OK0 A;  4DV5 T;  3UUX B;  4CXW A;  1E1H B;  4BA9 A;  2Q9Q A;  2XAJ B;  4X66 T;  3N9L A;  2V1D B;  4B6X A;  4LML A;  4DR3 T;  4PK6 A;  2E9X C;  4NUV A;  5HEU A;  3WI3 A;  5LMN T;  2MYS A;  4CI2 B;  3RYF E;  5HXC A;  3I0Q A;  1N36 T;  3KDS E;  4C90 A;  4I0U A;  5FKY A;  3ZT7 A;  2M6I A;  3PUA A;  1J1J A;  2RA1 A;  5JDM A;  4X20 E;  3O1H A;  4A56 A;  3BK9 A;  3TLS A;  4HKA A;  4ZI2 D;  2W0G A;  4AXP A;  1KNP A;  3KV4 A;  3ZMU B;  1US7 B;  3RIA A;  1W9R A;  4K0K T;  5L3F B;  3VKG A;  4PK5 A;  1MMN A;  4WYV A;  4NPP A;  4L0R A;  5FNV E;  2WMO A;  1T7S A;  2MOZ A;  3ESL A;  2N1G A;  3PUS A;  1UK5 A;  4ZI3 C;  3K3O A;  4UF0 A;  5J0Z A;  3RYC E;  4KX6 A;  1VCT A;  3DJB A;  2OLT A;  2WY2 A;  1AJ3 A;  3LG7 A;  3OJA A;  1D0X A;  3FBZ A;  1KF6 A;  5HCJ A;  3IEE A;  3RYI E;  5DQV A;  3EAB A;  2ZM0 A;  3ZEF B;  4AKL A;  4LF5 T;  1UUR A;  1FMV A;  3PUG A;  4HFV A;  3RPU A;  2X9Y A;  4WBN E;  3KFW X;  4YJ2 E;  5JDF A;  1Z0P A;  5FY7 A;  2JMH A;  4B3M T;  2PTF A;  2XQA A;  4AKR B;  4HEA A;  1HF8 A;  4LMK A;  3ETV A;  3ZCJ A;  2IHR 1;  5LOV E;  4LFB T;  4I50 E;  3WAJ A;  4IDQ A;  4KBM B;  3UQ7 A;  4J2C A;  2LLY A;  2ES0 A;  1D1C A;  5CA0 E;  2V8S V;  3ZMV B;  2DWG A;  5KXJ A;  2LSJ A;  3SRZ A;  2MBG A;  2BKN A;  4QX8 B;  4O2A E;  3CWZ B;  2SPC A;  4MFR A;  2VKO A;  4L5G A;  2VVN A;  4OYK A;  1BR4 A;  1QSD A;  3EHZ A;  4AQY T;  3RHW A;  1ZOY A;  3L09 A;  1L0V A;  4EXT A;  5DAB A;  2WCA A;  1NEN A;  4JI1 T;  5KDM C;  2OA5 A;  2BG9 E;  2V5C A;  1MMA A;  2J4G A;  2V6Y B;  2GK9 A;  4HFD A;  2ZM2 A;  3JC6 D;  2KLQ A;  1NWM X;  3ZMZ B;  3O4X E;  3OYX A;  3CML A;  2XM1 A;  2WM9 A;  2XAS B;  3HKB E;  1OED A;  1UGO A;  4NXM T;  2WB5 A;  3ZJ2 A;  4JYA T;  3OYZ A;  4IDP A;  2NTX A;  5JVD E;  2E5V A;  2UXX B;  4ZI2 C;  4AKH A;  2M6B A;  2ACZ A;  3ZYL A;  1MIY A;  3AE8 A;  4NXN T;  3F31 A;  4JI4 T;  4EYU A;  3H37 A;  4LF6 T;  3RIU A;  4EED A;  4H9Q C;  2KWH A;  2PFV A;  3T1Y T;  2I59 A;  5LG3 A;  4HWI B;  2KZ7 B;  5F8P A;  3EVY A;  4EOZ B;  5L4E A;  2UXB T;  3Q9D A;  3UFE A;  3N9M A;  2BDE A;  4LF9 T;  2WP9 A;  3TKL B;  5L3C B;  3GA8 A;  4DV6 T;  5LB7 B;  3P4R A;  4JI3 T;  4IDZ A;  2LRK A;  5FXX A;  2VUR A;  4QWN B;  4B3T T;  5AQQ B;  2CXL A;  2CM0 A;  4XAX B;  3AVR A;  3R84 B;  3AA7 B;  2HPJ A;  1XWM A;  1O3X A;  3VHL A;  1X79 A;  1OWA A;  5JR9 A;  4JI8 T;  2W62 A;  3N9N A;  4HWC A;  2HN1 A;  4EZ4 A;  1HCI A;  3LBX B;  4DVD A;  4IIJ E;  2LKH A;  2WAU A;  2QA7 A;  4B3S T;  2A9U A;  5LMU T;  2WQY A;  3PDY A;  5C2T A;  5HEJ A;  4X1Y E;  4IE5 A;  2X9H A;  4X1K E;  2UXC T;  2V7M A;  2BG9 C;  2VQF T;  4DR5 T;  2CXD A;  2QYW A;  2Y8D A;  3ZCI A;  4WZX A;  4H9N C;  1HX8 A;  1LVK A;  4EZH A;  3IHR A;  1HNZ T;  4WBO A;  2WSS V;  4HGA A;  5JDG A;  3I9W A;  2QRX A;  3CPZ A;  1BR0 A;  3ZT5 A;  3C4X A;  2VWA A;  4Z91 A;  4TZ4 C;  2K5B B;  5HXE A;  5AQF B;  3T8O A;  3N5L A;  1KNR A;  4KP3 C;  2DLR A;  3VU7 H;  2YN6 A;  2WWV A;  2DL1 A;  4OFZ A;  3K1S A;  3NZP A;  3UU3 A;  2VKH A;  1KEY A;  5FL0 A;  5LGT B;  1EZ3 A;  3OPC A;  4PJN A;  2RPA A;  4AKG A;  3VKH A;  1BR1 A;  4QHO A;  3AAI A;  3MZK B;  3RIF A;  4DUY T;  5JRC A;  4CQI A;  4IST A;  3JC6 C;  3ZYM A;  4HWH A;  2IC9 A;  4EYY R;  3FZH B;  2LHR A;  2UUA T;  5H6Q B;  4X64 T;  3CVR A;  3QB5 A;  3ONL C;  3U3I A;  2UXN B;  5AQL B;  5FVL A;  5FXZ A;  3T1H T;  1U5P A;  5L3E B;  5C3J A;  5J2U E;  4IL9 A;  4DMV A;  1SHZ C;  4GIW A;  4UVA B;  2DHR A;  3UQ4 A;  2HPL A;  1IZN B;  4HTE A;  4U72 A;  2XQ4 A;  2CRB A;  2XQ9 A;  3C50 A;  5ADX L;  5HXH A;  4PNI A;  3CX8 B;  2CE7 A;  5JDQ A;  4CN1 A;  1M62 A;  5EZY E;  3X1D A;  3SOL A;  1HFA A;  4CI1 B;  2Y6X A;  4CXX A;  1VOM A;  4A5X A;  3RRC A;  4IHJ E;  1OED C;  1D0Y A;  3P50 A;  4UEL A;  4PW8 A;  3KV9 A;  2LM9 A;  2N9D A;  3O1I A;  3PV0 F;  2X0Y A;  5F5W A;  4LF7 T;  4L9I A;  4O8S A;  5IHY A;  4U2Z A;  2UXD T;  3UUL A;  2BZB A;  2XQY A;  4U7I A;  3RIU C;  4IGU A;  4YSZ A;  2XQ6 A;  3J7Y q;  3ANW A;  3UU4 A;  4ZOL E;  2Q9Q B;  3P4S A;  2CHN A;  3SS1 A;  4HWD A;  4N78 D;  3AEB A;  2IW5 B;  5BR8 T;  1GQE A;  3NBX X;  1BR2 A;  5HWY A;  2YU1 A;  2X51 A;  1QLB A;  1S35 A;  4H9P C;  5JDH A;  3KVB A;  4V1A v;  3SFE A;  5JR9 C;  3NWI A;  4EEB A;  3MXZ A;  5LCY A;  2L3L A;  2WWU A;  5ETW A;  5HXR A;  3CIR A;  2EHO D;  5LJN A;  2DNX A;  2Y48 B;  1JNR A;  2D9D A;  1X9B A;  3ONX A;  4G2A A;  3UTK A;  3LK2 B;  4M1P A;  4YT0 A;  4WW0 A;  5AQT B;  2W67 A;  3UU5 A;  3RH3 A;  4CN4 A;  1HG2 A;  3ZPO A;  2PJQ A;  3A8Y C;  2L8K A;  3AE2 A;  2UU9 T;  5LP6 E;  4ANJ A;  4DR4 T;  1MIV A;  3PUW F;  3RC8 A;  3TLW A;  4UVC B;  3RX6 A;  5L4H A;  2XTL A;  4C91 A;  4GK5 E;  3C4Z A;  2H7O A;  3W15 B;  4DV2 T;  2NW9 A;  4TUY E;  3MJX A;  3AE7 A;  2ODU A;  1YXR A;  5F3J A;  2H88 A;  2WU2 A;  2BG9 A;  4YY3 T;  1IAP A;  3NZQ A;  2YDS A;  4DV3 T;  4G63 A;  2LSK A;  2CHO A;  2CA5 A;  4TNV A;  5AQR B;  1B7T A;  5L3G B;  1QUU A;  4TWD A;  2KSR A;  3CQX C;  4E7S A;  2J1D G;  2CWO A;  4H9S E;  2I6H A;  2V7K A;  5LJM A;  3KIN B;  5FXV A;  2C5K T;  4KI0 F;  3DP7 A;  4YXD A;  4X5T A;  3L8R A;  3ZC0 A;  1V9D A;  2CLY C;  3AE1 A;  3H3M A;  3BQL A;  4Q25 A;  5DQW A;  1E7P A;  1WFD A;  3PE0 A;  2XQ7 A;  2ZLY A;  3N2G E;  2IUB A;  4BJN A;  1WCR A;  4U31 A;  3AAE B;  5HEG A;  1N34 T;  3IBP A;  1OXZ A;  4U3C A;  1Y01 A;  3JAF A;  4GOU A;  1E2A A;  4DV0 T;  1J5W A;  5JTG A;  1UX4 A;  3LK3 B;  2CEA A;  1IBL T;  5J1G A;  4HFI A;  3HA4 A;  1MIW A;  2KIN B;  4H63 H;  2FJD A;  2A3D A;  3PUQ A;  3RQW A;  3UUB A;  5TAO A;  4DID B;  1KFY A;  4JEU B;  4MLK A;  3FXD B;  1XNR T;  3RQU A;  5L47 A;  4JI6 T;  1WYB A;  3MKD A;  2YEV C;  5FYM A;  3BQK A;  1WR6 A;  3K3N A;  1YQ4 A;  2QGS A;  3PTR B;  1NEK A;  4CI3 B;  4EGW A;  2CBJ A;  2JMK A;  2P9B A;  3UT5 E;  3C98 B;  2EHO C;  4LF8 T;  2FBW A;  3OVU A;  3C51 A;  3IF8 B;  3L3P A;  5IWA T;  2X67 A;  2E8I A;  5AQV B;  5M4Y A;  4EIW A;  4OX9 T;  3ZKR A;  2D2S A;  2IML A;  4UV9 B;  3SWH A;  2V6Y A;  5HCM A;  4OYJ A;  4JI5 T;  4X1I E;  4ASK A;  2BS2 A;  4QXC B;  3JAE A;  5EK3 A;  4JI2 T;  3TLV A;  1Y64 B;  4UXN B;  5J2T E;  3P7I A;  5HEH A;  2XJ7 A;  2D0T A;  2X0L B;  3KV6 A;  2YDQ A;  5FP3 A;  2CXF A;  3CX7 B;  4UV8 B;  2BS3 A;  3FXE B;  2JRK A;  2K48 A;  5FVK A;  3N2O A;  5BMV E;  2K3W A;  2C5I T;  2E5L T;  3N2K E;  1HR0 T;  2E9X B;  1XMQ T;  4IL4 A;  2CMR A;  2KND A;  2YK0 A;  1IBM T;  5LG4 A;  2XUE A;  5KX5 E;  1SE7 A;  1D0Z A;  1KK7 A;  2BVL A;  2H3R A;  4IE6 A;  3AE5 A;  2DI4 A;  4X65 T;  4GYR A;  5AFU L;  4ZHQ E;  4DR2 T;  3ZC1 A;  2V7J A;  4JUY A;  5AQK B;  3CX6 B;  3B57 A;  2J62 A;  3AEC A;  3EDV A;  4IE7 A;  4XZC A;  3AXJ A;  2FJB A;  1VRB A;  4O4J E;  1CUN A;  4P0B A;  3GWH A;  5AQH B;  4EV6 A;  2K24 A;  4TX5 A;  2XAG B;  3E0Z A;  3EI0 A;  4HFB A;  3JCF A;  4KHP T;  3LBX A;  2XQ3 A;  4ADZ A;  1HS7 A;  2XHE B;  5JDL A;  3VR8 A;  4F8H A;  1SUM B;  3EAM A;  4X62 T;  4YTN A;  4KHZ F;  5JH7 E;  1YW0 A;  3MA9 A;  3ETU A;  2E9X D;  2XY8 B;  3AEF A;  3AEE A;  1T72 A;  2WMN A;  4DV7 T;  3K3Q C;  4HN9 A;  4DO0 A;  1UUS A;  2NW7 A;  2BKO A;  4AIS A;  4HFE A;  4CN6 A;  1M7K A;  4BJM A;  3M65 A;  2XSB A;  3KVA A;  4NIQ A;  3HKD E;  3AED A;  1G8X A;  1MND A;  4PK4 A;  3I9Y A;  5ABG A;  4DR6 T;  5LXT E;  1I6Z A;  4AKI A;  4PJM A;  2BVM A;  1WLX A;  2NTY A;  3SFD A;  4ZZB A;  4QX7 B;  3A5X A;  3NVO A;  2B76 A;  2LKG A;  2NR4 A;  4JLE A;  5FMN A;  2IC6 A;  3ZJ1 A;  4Z8X A;  3AVS A;  5L2L A;  2JQ9 A;  2NP9 A;  5AQU B;  3ZYK A;  3GN5 A;  5AQG B;  4JI0 T;  3NKZ A;  4QXH B;  2IIU A;  3TLU A;  4CXY A;  4EB6 E;  2X9W A;  5EK2 A;  4AIU A;  4QH5 A;  2C0S A;  2AXD S;  5HXS A;  4P1N A;  3HKC E;  5E0O A;  3S4U A;  4YFS A;  4FI5 A;  3UUM A;  4GYS A;  2W2U A;  5IYZ E;  4E7Z A;  2YKS A;  2M67 A;  4HFH A;  3PUV F;  5JQG E;  2VK9 A;  2HN2 A;  4YSY A;  4ZI7 E;  2WZI A;  3ANW B;  2J47 A;  1FEW A;  4ILB A;  3VR9 A;  2EHO A;  3HL6 A;  4DV1 T;  2FUP A;  2YOE A;  1FJG T;  5LBQ B;  3ABV A;  3QK6 A;  5ABF A;  2MAW A;  2ZM8 A;  2LHN A;  4DBQ A;  1WRD A;  4PFP A;  4U7Y A;  3B13 A;  4AQG A;  4TV8 E;  3RLF F;  1MMG A;  3PJA A;  2JJ9 A;  2PBI A;  4GKK T;  1MNE A;  4HWF A;  2YU2 A;  4UVB B;  2UUC T;  3AA1 B;  1ZP0 A;  3MK7 C;  2X66 A;  3UU8 A;  2ODV A;  3FZK B;  1FIO A;  5CB4 E;  2VAS A;  2A2F X;  3AE3 A;  4DBR A;  1W09 A;  3AAA B;  1XDP A;  3ZMT B;  3V5U A;  2CBI A;  2HH7 A;  3V5S A;  2BBJ A;  5LHH B;  2NOX A;  1XZY A;  1I94 T;  4CZZ B;  2X0H A;  5LGN B;  1H7C A;  5LNK A;  2B1E A;  2X68 A;  1LKX A;  4ZZC A;  4GK0 E;  2LSG A;  2VL8 A;  3N9P A;  3QOF A;  3RC3 A;  1UCU A;  3KV5 A;  3O1J A;  2KT9 A;  5ABH A;  2WDV A;  2NWB A;  5FL1 A;  4F6R C;  3Q2M A;  2XAF B;  3P8C D;  3EUH A;  4UF0 B;  5JDN A;  3FZL B;  2W63 A;  3D0T A;  3E08 A;  2LEH A;  2Q9Q D;  3ZN0 B;  4MHC A;  2BG9 B;  2RP4 A;  1WR0 A;  1ZKE A;  4UEM A;  1ZHC A;  2R6G F;  2VB6 A;  1YD8 G;  3RYH E;  4BAY B;  3OTO T;  2G0U A;  2X9X A;  1ZV4 X;  2K9A A;  4U33 A;  5FY1 A;  1LRZ A;  3AE6 A;  2XAH B;  3DTO A;  4P0A A;  5C8Y E;  1VCS A;  1HG5 A;  4O4H E;  2OV9 A;  3FZM B;  4QH1 A;  1Z8U A;  3QB5 K;  1S94 A;  4YHJ A;  1R8I A;  3AEA A;  4O4L E;  5IUX A;  5AQJ B;  2CWY A;  4YTM A;  4ZXL A;  4TV9 E;  1N33 T;  3PUX F;  4JEH B;  3N9Q A;  2W4X A;  3F2E A;  3JAD A;  2D5U A;  3WAK A;  2KMF A;  4YJ3 E;  2XZE A;  3PU3 A;  2KWI B;  4P09 A;  3AE4 A;  2L9Q A;  5LYJ E;  3FZF B;  3OKQ A;  1T8B A;  3RI5 A;  2HHH T;  4IE4 A;  3OBV E;  1W0B A;  4KMC A;  5DJQ C;  2IAK A;  2NW8 A;  3ZLI A;  3LJC A;  4YHH T;  3Q5E A;  5CGM A;  2W66 A;  4A98 A;  5HAX A;  2FJA A;  2XAQ B;  1IBK T;  5FY0 A;  3P4W A;  4YLH A;  2JQK A;  3AE9 A;  2LE8 A;  2JPF A;  4Z90 A;  5LHG B;  1HNW T;  2QVA A;  4QXB B;  3RKG A;  3I1A A;  4ZS2 A;  4TWF A;  2N2N A;  3PUZ F;  2PG8 A;  5ABE A;  2ZM6 T;  5LA6 E;  1WYC A;  3VRB A;  5HYA A;  5HWX A;  5FXW A;  3RKO A;  4AQF A;  1ZEE A;  1SA0 E;  4GKJ T;  1OED B;  3Q5X A;  2JIW A;  1XDO A;  4IDN A;  1MMD A;  3CQC B;  3FB2 A;  4H63 V;  4UIG A;  3GMI A;  1HNX T;  4KUM B;  4PAG A;  3KBT A;  2KXP B;  2Z6E A;  3ZST A;  3QNU A;  2CCQ A;  1FMW A;  2BS4 A;  4H9O C;  4K0U A;  4B3R T;  1HTJ F;  3C4W A;  2V7I A;  5CA1 E;  1XMO T;  3Q5W A;  2W61 A;  2FJE A;  2Q9Q C;  4ILU A;  3HKE E;  3AB3 B;  3PUR A;  4FJO A;  4NUU A;  3LK4 2;  4LFC T;  3PJA J;  3P4Q A;  3CQG B;  2V7L A;  5JRE A;  4O2B E;  1YKE B;  3LFM A;  3AEG A;  4DV4 T;  5L3B B;  1J5E T;  2A72 A;  3L39 A;  4LMJ A;  3NRX A;  2VKJ A;  3TLT A;  3PU8 A;  2MTQ A;  5JR9 B;  5LHI B;  3G06 A;  1NAF A;  2WDR A;  4DMW A;  1IJ5 A;  2W00 A;  4ILC A;  3UUN A;  3ZN1 B;  4PJL A;  2XPK A;  5AQM B;  2V26 A;  2AE9 A;  4ISS A;  2LOP A;  3AXJ B;  2E9X A;  5AQO B;  5L3D B;  4LF4 T;  3CKD A;  4OHF A;  2IDO B;  3ONJ A;  4WNK A;  4U2Y A;  3EDU A;  2LSI A;  4DND A;  4COF A;  5CFB A;  2DWK A;  3F57 A;  4TNW A;  4HE8 A;  4O4I E;  3HI2 A;  2ACX A;  2H89 A;  4ZS3 A;  3ZSS A;  3UFG A;  5AQN B;  3CK6 A;  4IT4 A;  2D0U A;  2F4V T;  2C5J A;  2H7V C;  1D1A A;  2JQH A;  4MBQ A;  5A1L A;  1D1B A;  3O9X A;  4LFA T;  1YQ3 A;  3ZT6 A;  3AA6 B;  4IE0 A;  3U78 A;  1OED E;  2YIN A;  1XNQ T;  3H3A A;  5LBM A;  2LM2 A;  2BBH A;  2XQ8 A;  2XQ5 A;  2V6X A;  1JNZ A;  4YTP A;  2WS3 A;  3Q5D A;  3LSV A;  4DUZ T;  2XM2 A;  2WU5 A;  2WDQ A;  4U74 A;  2CPT A;  5JRC B;  5AQI B;  3A7M A;  3C64 A;  3I0O A;  3QUJ A;  3J9X 1;  3RGL A;  4TN7 B;  3E22 E;  4IDO A;  5AQS B;  2E2A A;  3HR0 A;  3P4P A;  4PJJ A;  1W0A A;  1IJ6 A;  3QC9 A;  2CLY B;  4ERR A;  4ZEY A;  2I0M A;  4ILA A;  2VVS A;  3K8P C;  1UX5 A;  5CJ5 A;  4QH4 A;  2XSA A;  3MAC A;  3N9O A;  3UU6 A;  3R6N A;  4AI6 A;  3GN5 B;  3BQI A;  4ZI3 D;  1LVF A;  2YDR A;  1HX1 B;  3AA0 B;  5HEO A;  4I43 B;  3RRW A;  4QKN A;  3LDQ B;  4MAL A;  4JV5 T;  1U4Q A;  1CHU A;  3ZMS B;  2ZMA A;  1DU2 A;  4AQF C;  3PUY F;  4TWH A;  1KNZ A;  2VKD A;  3VRA A;  2WBL A;  4UR9 A;  4HFC A;  4H9R C;  2UUB T;  4EAH A;  5GON E;  4XBF B;  1YKH B;  2DCF A;  5EK4 A;  5H6R B;  2BKP A;  3B5M A;  2WZH A;  5KMG P;  2LOS A;  2JQQ A;  3RF1 A;  2EHO B;  4YSX A;  1G73 A;  2LRL A;  3KBU A;  2LJL A;  2VL0 A;  1N32 T;  5AQP B;  5ABF B;  2LSY A;  4A97 A;  4JI7 T;  4IRE A;  5LGU B;  4PFO A;  3FHN A; 
#chains in the Genus database with same CATH homology
 5AQU B;  4HWH A;  5AQO B;  5AQQ B;  4HWI B;  3FZH B;  5AQI B;  1HX1 B;  5AQN B;  3FZK B;  5AQT B;  4HWD A;  5AQG B;  1T7S A;  3FZL B;  5AQJ B;  5AQL B;  3M3Z B;  1UK5 A;  3A8Y C;  3FZF B;  1UGO A;  5AQP B;  5AQM B;  4HWC A;  5AQR B;  5AQH B;  5AQS B;  1M7K A;  1I6Z A;  5AQF B;  3LDQ B;  5AQV B;  5AQK B;  4HWF A;  3FZM B;  1M62 A;  2D9D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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