5AQMB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
112
structure length
112
Chain Sequence
GSNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 44
structure length 112
sequence length 112
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqmB00
1M7KA 3FZFB 5AQUB 1UK5A 3LDQB 4HWDA 5AQNB 5AQFB 3FZHB 4HWCA 5AQKB 5AQTB 5AQMB 4HWIB 5AQOB 1HX1B 5AQHB 3FZMB 1I6ZA 3FZKB 3FZLB 4HWHA 3M3ZB 5AQQB 4HWFA 5AQIB 1UGOA 2D9DA 5AQLB 5AQVB 1T7SA 1M62A 5AQRB 5AQSB 5AQGB 3A8YC 5AQPB 5AQJB
chains in the Genus database with same CATH superfamily
3C50A 1ZKEA 2Y8DA 2WM9A 2YK0A 3K3QC 3RKGA 2VKHA 5LJMA 3EVYA 5JRCA 3PDYA 4ILBA 5JQGE 2D9DA 4FI5A 3PUXF 4IE4A 3MZKB 3QUJA 4DV4T 2V7KA 3EHZA 3I1AA 3NWIA 2H7VC 3X1DA 3A5XA 2JPFA 3PJAJ 4BJNA 3TLTA 3A7MA 4H9SE 2VASA 2BBJA 2B1EA 2UXNB 5LP6E 3JAFA 3L3PA 1XMQT 3ZT5A 1UCUA 3LDQB 2QGSA 5F5WA 1O3XA 2KMFA 1WR0A 4YJ3E 3CVRA 4HFBA 4OX9T 3JC6D 4KBMB 5L47A 3AE9A 4B3MT 4CI1B 4M1PA 1Y64B 2W61A 4PAGA 1IBMT 4EYUA 3AEGA 3I0QA 1FMWA 3GA8A 2MPKA 4HWHA 5EK4A 2LM9A 1S94A 3U78A 4OHFA 4X64T 4EIWA 2WY2A 3UFGA 2J1DG 3RC8A 2NTXA 5KMGP 3N9MA 4EYYR 2E5LT 3LJCA 4DV6T 4PJNA 1UUSA 2NR4A 1UX4A 1UGOA 4B3ST 2HH7A 2YDRA 5HAXA 3R84B 3PUSA 4HFIA 2Z6EA 3QNUA 3KFWX 5EZYE 5LJNA 4X20E 4IDOA 5GONE 1LVFA 3RIUA 3AEDA 4AKIA 5AQMB 2DCFA 3LBXB 4N78D 1WR6A 3PU3A 3CMLA 3ZT6A 3KV6A 4EEBA 2W4XA 3LK42 2JMHA 1B7TA 5FXWA 3LFMA 2BZBA 1J1JA 4JI4T 4YJ2E 2VWAA 1W09A 3O9XA 4P09A 3RGLA 4U3CA 3AA0B 1Z0PA 4UVBB 4BAYB 2EHOD 1YD8G 4ZI3D 5IWAT 3UUNA 4EZHA 2PBIA 3KV9A 1N32T 5AQOB 4EB6E 4IE7A 4I4TE 2V26A 5LNKA 1BR0A 3WI3A 4YSXA 4EXTA 4NPPA 1LRZA 3AAAB 4ANJA 3KINB 4IREA 3SWHA 4LF5T 1BR1A 3TLWA 4GKJT 2K9AA 2XM2A 3ZMZB 4DV2T 5J2UE 1AJ3A 5JDLA 2CBIA 2BG9A 4OYKA 4YSYA 3N9NA 3AE6A 5LMUT 1BR2A 5HWYA 1U4QA 5LOVE 4ERRA 4DV0T 4PNIA 1SHZC 3FZMB 3ZCIA 3ZKRA 4V1Av 3BQLA 4GOUA 5FXVA 3S4UA 4QH4A 3ZMUB 1OEDC 5LGTB 4JBWF 2JRKA 2QYWA 5L4EA 3C4WA 5L3DB 4BJMA 5LG4A 4O4IE 4I43B 3IBPA 3PUWF 3ZYLA 1HS7A 2LHNA 4JI6T 3ZT7A 4B3RT 5HXEA 3AE4A 2X68A 5AQUB 2NWBA 2CWYA 3PTRB 3ESLA 5C8YE 4JEUB 5HEGA 4QH1A 3EDUA 3V5SA 4IDQA 3FZKB 3LSVA 3VR8A 4EAHA 3JAEA 2QVAA 4DV5T 3HKEE 1KNRA 3LBXA 4L5GA 2V7LA 4A56A 2J4GA 2G0UA 1GQEA 1Y01A 5KX5E 1ZEEA 4PFPA 4U7IA 1G73A 3AA6B 3EABA 2PTFA 3C64A 3A8YC 4DBRA 5LGNB 4UVAB 3P4RA 2KINB 2LKGA 2ZM6T 3KV5A 1MNDA 5LMNT 3PJAA 3E22E 4CXWA 3PE0A 1FIOA 5HEJA 2CMRA 2D5UA 2D0UA 4JI5T 2XTLA 4LF7T 4DV1T 4YTPA 5CA1E 2LSGA 1UX5A 3UU4A 5L4HA 4AKGA 2XQ4A 3ZCJA 4HFCA 3ZLIA 2X0LB 3RX6A 4DUYT 1D0XA 3QC9A 5ABHA 2Y48B 3KBUA 4IDPA 4GYRA 3HA4A 5FKYA 4LFAT 5A1LA 3SFEA 1HNZT 2HPLA 2VVNA 1IJ5A 3ZMVB 4DMVA 3Q2MA 2R6GF 2W00A 2M6IA 3HKCE 4DR6T 1T98A 3WAKA 5EK2A 3FB2A 5C2TA 3CX7B 4COFA 2DI4A 2CCQA 5FY1A 4KUMB 2DNXA 3J7Yq 1D0YA 4LMLA 3ZC1A 3RRCA 3Q9DA 4LFCT 4KHZF 4UV8B 4P0BA 1OEDA 5AQPB 4GYSA 1WYCA 2IW5B 3U3IA 2NW8A 3P4SA 3VRAA 2W62A 4ZI2C 2PG8A 4DUZT 3E08A 1S35A 2XQAA 4TNWA 4KHPT 1HCIA 4X1KE 3ZPOA 4YTMA 5HWXA 1JNZA 5JDNA 1XWMA 1M7KA 4JV5T 1ZP0A 1NENA 2L9QA 2Q9QC 4CQIA 4EOZB 2UXCT 2LE8A 1E1HB 2D0TA 1XNRT 2YDQA 5L2LA 4H9QC 2Q9QB 2UU9T 1W9RA 3FBZA 4GK5E 2DWKA 2ZM0A 3VRBA 4PK4A 4H63H 1YQ3A 1N36T 1XNQT 3MXZA 4HWFA 2K24A 2YOEA 5L3BB 2DLRA 1MIVA 3AE7A 4JEHB 4WYVA 1Z8UA 5AQSB 5JR9C 2XAFB 4DR4T 1UK5A 4YY3T 1HNWT 3ZJ1A 4HGAA 1KF6A 4WZXA 3O1JA 4JYAT 2BKPA 4A97A 3G06A 5JR9B 2BKNA 4AIUA 4GIWA 4MLKA 4IL9A 5CFBA 4PJJA 1MMNA 1HX8A 2ACZA 2ZM8A 5JH7E 3MJXA 2V6YB 5L3EB 3VKGA 1SA0E 4WW0A 2N1GA 3N9LA 2V7MA 2RA1A 3H3AA 1V9DA 2UUCT 1MMGA 3OYXA 4U2YA 2BVLA 5L3GB 2W2UA 2JQHA 4LF4T 2WWVA 1KNZA 1SUMB 4JI8T 4H63V 1H7CA 2XSBA 1NEKA 4H9PC 3ETVA 2UXDT 1VCTA 4QHOA 4TN7B 5L3CB 5HEHA 4U72A 2CA5A 4A5XA 3UULA 2IAKA 4O8SA 1ZHCA 4HEAA 5FNVE 1OWAA 3HR0A 5J0ZA 1OXZA 3AXJB 2FUPA 4AQFC 2JQQA 5CJ5A 5DQWA 3P4WA 3HKBE 5HEOA 2VURA 3K8PC 2JMKA 3ZMSB 2X9YA 4Z91A 4IL4A 1WRDA 4UF0B 2WB5A 4B6XA 4C91A 2NW9A 4IE5A 5LBQB 4ISTA 2BS3A 2H89A 4IDZA 4NUUA 3UUMA 1KK7A 1FMVA 5CA0E 2X51A 2CEAA 3RIFA 4UEMA 5AQKB 5TAOA 5ADXL 4IGUA 1YKEB 2CXDA 2A3DA 2FJBA 1HG5A 3C4XA 3ZSTA 4KMCA 4NXNT 4LMJA 4UIGA 2YDSA 5HXRA 2WMNA 4PK6A 3MACA 5DJQC 5FMNA 2MBGA 4UR9A 5HEUA 1QLBA 2IC9A 1HX1B 3F57A 3N9OA 1QUUA 2D2SA 5J2TE 3OJAA 5FY7A 3CQGB 4YT0A 4ZI3C 3FBLA 1R8IA 2NTYA 3IEEA 2WU2A 2GK9A 2E9XA 5JDHA 3J9X1 3K3OA 1YKHB 2VQET 2WS3A 2X9XA 2BG9E 2V6XA 5AQLB 2J47A 2JJ9A 4XAXB 4MHCA 2V6YA 3JCFA 2OA5A 3NVOA 2QRXA 4HWDA 3L8RA 3AECA 3TKLB 5AQQB 4ILAA 4HFDA 4TX5A 2K5BB 1HFAA 3RIAA 1DU2A 2KWIB 2KWHA 2LEHA 3UTKA 4Z90A 4QX8B 2XZEA 5LA6E 4BA9A 3M3ZB 3P50A 1E7PA 4IE6A 1T7SA 2C5IT 4HFVA 2KNDA 4I50E 4AISA 4YHJA 2XQ5A 3DP7A 3AXJA 4IE0A 2LT3A 5FXZA 3ONXA 2ZM2A 1WCRA 4ZS3A 4P1NA 4X1IE 5AQVB 1I94T 1W0AA 2VL8A 3Q5EA 2ACXA 4NUVA 1WFDA 1N34T 4DR1T 5F8PA 4G63A 2WU5A 3KBTA 5JDQA 2M6BA 3ANWB 1HR0T 3ZYMA 3FZHB 2ODVA 2C5KT 2DWGA 4JLEA 3QB5K 2QA7A 3N9QA 3C51A 3QOFA 4KX6A 4C90A 4AKLA 2SPCA 1VOMA 3I0OA 4U74A 2XUEA 3C98B 3AEEA 5AQNB 4DV7T 3RH3A 5HXCA 4UVCB 3GWHA 4LMKA 3UQ4A 1FEWA 3UU3A 1IBKT 3RPUA 2JQ9A 1J5WA 5F3JA 4LF6T 1IJ6A 3RYCE 4JI0T 3NKZA 5LBMA 2BDEA 1E2AA 2PJQA 2A72A 5IYZE 4ZHQE 3CX6B 4IDNA 3NRXA 4DR5T 4E7ZA 2V1DB 2DL1A 3NBXX 3M65A 4HKAA 4YHHT 3RHWA 3ZSSA 3T8OA 2LJLA 4OYJA 5LB7B 3RRWA 1OEDE 1KEYA 4AKRB 2FJDA 4H9RC 4HN9A 4U2ZA 1L0VA 1D1AA 5KDMC 3MK7C 2L8KA 3F2EA 3AE3A 2H3RA 4DBQA 2K48A 3TLVA 2CXLA 5KXJA 1YQ4A 4HE8A 2BKOA 3F31A 5JRCB 3PUVF 4QH5A 2LLYA 4DNDA 1NWMX 1NAFA 3V5UA 3MKDA 1XMOT 3KVAA 2UXBT 2FJAA 4I0UA 4YXDA 5FXXA 5M4YA 3P7IA 4ZI7E 3CKDA 3UU8A 4O2BE 3EI0A 2LOPA 2Y6XA 3BK9A 3TLUA 3WAJA 2NP9A 3SFDA 1YXRA 1QSDA 4ZOLE 3ANWA 3W15B 2WQYA 2CBJA 2WDQA 3GMIA 3NZQA 3K3NA 2CHOA 3I9YA 5FL1A 3B13A 2VQFT 2YU2A 3RQWA 4ASKA 3EUHA 3SRZA 2WSSV 1US7B 2XASB 1CUNA 3PUYF 4MBQA 1VCSA 4DO0A 3UQ7A 2I0MA 3AEBA 4F8HA 4HWIB 4ZI2D 1UURA 3AA1B 4WNKA 2CRBA 3L09A 1YW0A 3AEFA 4TV8E 1HF8A 3ONJA 4JI1T 4CN4A 2X0YA 2KLQA 3RIUC 2MAWA 3ZN1B 5FL0A 4EEDA 3AVRA 4TWDA 2AE9A 3KDSE 2VKJA 2M67A 2IC6A 2Q9QD 3PUAA 5C3JA 4ADZA 4PJLA 3OVUA 3O1HA 3LK2B 3FXEB 3ABVA 4UV9B 4NIQA 2VKOA 4WBOA 1MMAA 2HHHT 5AQFB 3AE5A 2WZIA 5HCMA 2LKHA 5ABFB 3UU5A 3FZLB 4L0RA 2XSAA 3MA9A 2KXPB 3CK6A 2XQ7A 2RPAA 2KSRA 2ODUA 4CI3B 2E9XD 3AA7B 1T72A 3TLSA 3VR9A 4OFZA 4KP3C 3UUXB 2OLTA 3N5LA 3JC6C 4L9IA 2XQ8A 3T1HT 2X9WA 4LF8T 4CN1A 1M62A 4JI3T 1G8XA 3QB5A 4IHJE 4ISSA 5AQGB 2ZLYA 1IAPA 2CXFA 2XQYA 4F6RC 4EGWA 2HN2A 4CXYA 4K0UA 4OK0A 4K0KT 3DTOA 2BG9C 4EV6A 3NZPA 3R6NA 2BG9B 2WDRA 4U7YA 3FHNA 2F4VT 1ZOYA 3I9WA 2KZ7B 5LXTE 2YEVC 2CWOA 3H37A 4ZS2A 3IF8B 3ZEFB 2X0HA 5HXHA 1D0ZA 4AXPA 4HTEA 4QXBB 2XAQB 2IMLA 2L3LA 2V8SV 4YFSA 4A98A 4E7SA 2PFVA 2UUBT 4AI6A 2CLYC 2MOZA 5LYJE 3PUZF 2Q9QA 3GN5B 5E0OA 2WDVA 5ABEA 4QKNA 4JI7T 3SOLA 5FVKA 2CLYB 3CWZB 5FY0A 3RI5A 3AE1A 1VRBA 3RC3A 2VL0A 2X66A 2B76A 2LRLA 2W63A 4TZ4C 2C0SA 2XY8B 2EHOC 1WYBA 1XDOA 3RKOA 1HG2A 5HXSA 5CB4E 5JR9A 3BQIA 4DR7T 2EHOB 2CPTA 2IHR1 1BR4A 3RLFF 5AQIB 5ABGA 4O4HE 1IBLT 4X5TA 2C5JA 3K1SA 4XBFB 2WP9A 5ABFA 4U31A 3PUGA 3QK6A 3RYFE 4CZZB 2N9DA 3N2GE 4EZ4A 3B57A 3CQCB 3SS1A 2W66A 2YINA 4LF9T 3PU8A 3P8CD 2CHNA 4ZZBA 3UT5E 2YN6A 3AEAA 5AQTB 2HPJA 2XJ7A 2XAHB 1FJGT 3AE8A 4XZCA 2DHRA 3CQXC 4JUYA 2V5CA 3RF1A 4DV3T 3ETUA 3P4PA 4O2AE 1X79A 3C4ZA 4IT4A 4CXXA 2XAJB 5JDMA 1JNRA 4WBNE 2LSJA 5L3FB 1D1CA 4H9NC 4MFRA 1X9BA 2I6HA 3RYHE 5ETWA 4TWFA 2IDOB 3O1IA 3ZN0B 3CIRA 5HCJA 4LFBT 4PK5A 5LHIB 5DQVA 2BVMA 4AQFA 4UF0A 5FYMA 3LG7A 2MYSA 2W0GA 3HL6A 1KFYA 5J1GA 2N2NA 3AVSA 5FP3A 5AQRB 2FBWA 5DABA 4G2AA 2YU1A 4CI2B 1OEDB 3GN5A 1WLXA 2P9BA 3OKQA 3ZJ2A 2I59A 4IIJE 3VKHA 5LCYA 1MIWA 2XPKA 2X9HA 4TWHA 3Q5DA 4DIDB 3VHLA 2E8IA 2NW7A 4GKKT 5JDFA 4ILCA 4FJOA 2X67A 3NRYA 5EK3A 5FVLA 3N2KE 4U33A 2YKSA 4QWNB 1XDPA 4DR3T 4PW8A 2XAGB 5CGMA 2EHOA 3E0ZA 4I55E 2WMOA 4QX7B 3IA3A 3VU7H 4NXMT 4AQYT 3EAMA 4AKHA 4B3TT 4QXCB 3L39A 4ZXLA 4J2CA 2A2FX 4UXNB 2ZMAA 4TV9E 3HKDE 4O4JE 4X65T 5BMVE 4HWCA 3UFEA 2XQ6A 3IHRA 2V5DA 2CM0A 2W67A 2KT9A 1MNEA 3O4XE 2JQKA 2UUAT 2ES0A 2BS4A 2VK9A 4JI2T 5AQJB 3P4QA 3FZFB 2VVSA 2IUBA 4O4LE 2VB6A 4MALA 2CE7A 3AAEB 2XM1A 2AXDS 3OPCA 4DR2T 3FXDB 4UELA 5JVDE 3LK3B 4GK0E 3UU6A 2WBLA 5H6QB 3OBVE 2H7OA 3UUBA 3AAIA 2UXXB 5LG3A 2WWUA 2XQ3A 4YTNA 4AQGA 2LSYA 2JIWA 3PV0F 3JADA 3PURA 4X1YE 4HFHA 5JREA 1SE7A 3N9PA 3CX8B 2HN1A 2H88A 3T1YT 5LHHB 2BBHA 2XQ9A 2LSIA 3AE2A 1HNXT 2K3WA 4KI0F 4PJMA 5HYAA 1ZV4X 4PFOA 5H6RB 4YSZA 3ZYKA 4TNVA 3PUQA 4X66T 1LKXA 5LGUB 3AB3B 4QXHB 2E2AA 2LRKA 3H3MA 3RQUA 3KV4A 2RP4A 5AQHB 4P0AA 1U5PA 2V7JA 3DJBA 2OV9A 1EZ3A 1T8BA 3CPZA 3ZMTB 2VKDA 1CHUA 2LM2A 3OYZA 4H9OC 1MIYA 2IIUA 2LHRA 2WCAA 2BS2A 4X62T 5JTGA 5IHYA 1MMDA 1D1BA 2J62A 4ZZCA 2A9UA 3HI2A 4HFEA 2LSKA 4DVDA 1KNPA 2V7IA 3Q5XA 3EDVA 1IZNB 4DMWA 5BR8T 1HTJF 2FJEA 3BQKA 3KVBA 3RYIE 3ZC0A 5JDGA 3OTOT 4YLHA 2WZHA 4ILUA 3D0TA 3Q5WA 2E9XC 5IUXA 2NOXA 4TUYE 1W0BA 1J5ET 3B5MA 1XZYA 2LOSA 5AFUL 3ONLC 5LHGB 2E9XB 1I6ZA 2WAUA 4CN6A 3N2OA 2E5VA 2XHEB 4Z8XA 1LVKA 4Q25A 4ZEYA 1N33T 2MTQA
chains in the Genus database with same CATH topology
1M7KA 3FZFB 5AQUB 1UK5A 3LDQB 4HWDA 5AQNB 5AQFB 3FZHB 4HWCA 5AQKB 5AQTB 5AQMB 4HWIB 5AQOB 1HX1B 5AQHB 3FZMB 1I6ZA 3FZKB 3FZLB 4HWHA 3M3ZB 5AQQB 4HWFA 5AQIB 1UGOA 2D9DA 5AQLB 5AQVB 1T7SA 1M62A 5AQRB 5AQSB 5AQGB 3A8YC 5AQPB 5AQJB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M7K A;  3FZF B;  5AQU B;  1UK5 A;  3LDQ B;  4HWD A;  5AQN B;  5AQF B;  3FZH B;  4HWC A;  5AQK B;  5AQT B;  5AQM B;  4HWI B;  5AQO B;  1HX1 B;  5AQH B;  3FZM B;  1I6Z A;  3FZK B;  3FZL B;  4HWH A;  3M3Z B;  5AQQ B;  4HWF A;  5AQI B;  1UGO A;  2D9D A;  5AQL B;  5AQV B;  1T7S A;  1M62 A;  5AQR B;  5AQS B;  5AQG B;  3A8Y C;  5AQP B;  5AQJ B; 
#chains in the Genus database with same CATH topology
 3C50 A;  1ZKE A;  2Y8D A;  2WM9 A;  2YK0 A;  3K3Q C;  3RKG A;  2VKH A;  5LJM A;  3EVY A;  5JRC A;  3PDY A;  4ILB A;  5JQG E;  2D9D A;  4FI5 A;  3PUX F;  4IE4 A;  3MZK B;  3QUJ A;  4DV4 T;  2V7K A;  3EHZ A;  3I1A A;  3NWI A;  2H7V C;  3X1D A;  3A5X A;  2JPF A;  3PJA J;  4BJN A;  3TLT A;  3A7M A;  4H9S E;  2VAS A;  2BBJ A;  2B1E A;  2UXN B;  5LP6 E;  3JAF A;  3L3P A;  1XMQ T;  3ZT5 A;  1UCU A;  3LDQ B;  2QGS A;  5F5W A;  1O3X A;  2KMF A;  1WR0 A;  4YJ3 E;  3CVR A;  4HFB A;  4OX9 T;  3JC6 D;  4KBM B;  5L47 A;  3AE9 A;  4B3M T;  4CI1 B;  4M1P A;  1Y64 B;  2W61 A;  4PAG A;  1IBM T;  4EYU A;  3AEG A;  3I0Q A;  1FMW A;  3GA8 A;  2MPK A;  4HWH A;  5EK4 A;  2LM9 A;  1S94 A;  3U78 A;  4OHF A;  4X64 T;  4EIW A;  2WY2 A;  3UFG A;  2J1D G;  3RC8 A;  2NTX A;  5KMG P;  3N9M A;  4EYY R;  2E5L T;  3LJC A;  4DV6 T;  4PJN A;  1UUS A;  2NR4 A;  1UX4 A;  1UGO A;  4B3S T;  2HH7 A;  2YDR A;  5HAX A;  3R84 B;  3PUS A;  4HFI A;  2Z6E A;  3QNU A;  3KFW X;  5EZY E;  5LJN A;  4X20 E;  4IDO A;  5GON E;  1LVF A;  3RIU A;  3AED A;  4AKI A;  5AQM B;  2DCF A;  3LBX B;  4N78 D;  1WR6 A;  3PU3 A;  3CML A;  3ZT6 A;  3KV6 A;  4EEB A;  2W4X A;  3LK4 2;  2JMH A;  1B7T A;  5FXW A;  3LFM A;  2BZB A;  1J1J A;  4JI4 T;  4YJ2 E;  2VWA A;  1W09 A;  3O9X A;  4P09 A;  3RGL A;  4U3C A;  3AA0 B;  1Z0P A;  4UVB B;  4BAY B;  2EHO D;  1YD8 G;  4ZI3 D;  5IWA T;  3UUN A;  4EZH A;  2PBI A;  3KV9 A;  1N32 T;  5AQO B;  4EB6 E;  4IE7 A;  4I4T E;  2V26 A;  5LNK A;  1BR0 A;  3WI3 A;  4YSX A;  4EXT A;  4NPP A;  1LRZ A;  3AAA B;  4ANJ A;  3KIN B;  4IRE A;  3SWH A;  4LF5 T;  1BR1 A;  3TLW A;  4GKJ T;  2K9A A;  2XM2 A;  3ZMZ B;  4DV2 T;  5J2U E;  1AJ3 A;  5JDL A;  2CBI A;  2BG9 A;  4OYK A;  4YSY A;  3N9N A;  3AE6 A;  5LMU T;  1BR2 A;  5HWY A;  1U4Q A;  5LOV E;  4ERR A;  4DV0 T;  4PNI A;  1SHZ C;  3FZM B;  3ZCI A;  3ZKR A;  4V1A v;  3BQL A;  4GOU A;  5FXV A;  3S4U A;  4QH4 A;  3ZMU B;  1OED C;  5LGT B;  4JBW F;  2JRK A;  2QYW A;  5L4E A;  3C4W A;  5L3D B;  4BJM A;  5LG4 A;  4O4I E;  4I43 B;  3IBP A;  3PUW F;  3ZYL A;  1HS7 A;  2LHN A;  4JI6 T;  3ZT7 A;  4B3R T;  5HXE A;  3AE4 A;  2X68 A;  5AQU B;  2NWB A;  2CWY A;  3PTR B;  3ESL A;  5C8Y E;  4JEU B;  5HEG A;  4QH1 A;  3EDU A;  3V5S A;  4IDQ A;  3FZK B;  3LSV A;  3VR8 A;  4EAH A;  3JAE A;  2QVA A;  4DV5 T;  3HKE E;  1KNR A;  3LBX A;  4L5G A;  2V7L A;  4A56 A;  2J4G A;  2G0U A;  1GQE A;  1Y01 A;  5KX5 E;  1ZEE A;  4PFP A;  4U7I A;  1G73 A;  3AA6 B;  3EAB A;  2PTF A;  3C64 A;  3A8Y C;  4DBR A;  5LGN B;  4UVA B;  3P4R A;  2KIN B;  2LKG A;  2ZM6 T;  3KV5 A;  1MND A;  5LMN T;  3PJA A;  3E22 E;  4CXW A;  3PE0 A;  1FIO A;  5HEJ A;  2CMR A;  2D5U A;  2D0U A;  4JI5 T;  2XTL A;  4LF7 T;  4DV1 T;  4YTP A;  5CA1 E;  2LSG A;  1UX5 A;  3UU4 A;  5L4H A;  4AKG A;  2XQ4 A;  3ZCJ A;  4HFC A;  3ZLI A;  2X0L B;  3RX6 A;  4DUY T;  1D0X A;  3QC9 A;  5ABH A;  2Y48 B;  3KBU A;  4IDP A;  4GYR A;  3HA4 A;  5FKY A;  4LFA T;  5A1L A;  3SFE A;  1HNZ T;  2HPL A;  2VVN A;  1IJ5 A;  3ZMV B;  4DMV A;  3Q2M A;  2R6G F;  2W00 A;  2M6I A;  3HKC E;  4DR6 T;  1T98 A;  3WAK A;  5EK2 A;  3FB2 A;  5C2T A;  3CX7 B;  4COF A;  2DI4 A;  2CCQ A;  5FY1 A;  4KUM B;  2DNX A;  3J7Y q;  1D0Y A;  4LML A;  3ZC1 A;  3RRC A;  3Q9D A;  4LFC T;  4KHZ F;  4UV8 B;  4P0B A;  1OED A;  5AQP B;  4GYS A;  1WYC A;  2IW5 B;  3U3I A;  2NW8 A;  3P4S A;  3VRA A;  2W62 A;  4ZI2 C;  2PG8 A;  4DUZ T;  3E08 A;  1S35 A;  2XQA A;  4TNW A;  4KHP T;  1HCI A;  4X1K E;  3ZPO A;  4YTM A;  5HWX A;  1JNZ A;  5JDN A;  1XWM A;  1M7K A;  4JV5 T;  1ZP0 A;  1NEN A;  2L9Q A;  2Q9Q C;  4CQI A;  4EOZ B;  2UXC T;  2LE8 A;  1E1H B;  2D0T A;  1XNR T;  2YDQ A;  5L2L A;  4H9Q C;  2Q9Q B;  2UU9 T;  1W9R A;  3FBZ A;  4GK5 E;  2DWK A;  2ZM0 A;  3VRB A;  4PK4 A;  4H63 H;  1YQ3 A;  1N36 T;  1XNQ T;  3MXZ A;  4HWF A;  2K24 A;  2YOE A;  5L3B B;  2DLR A;  1MIV A;  3AE7 A;  4JEH B;  4WYV A;  1Z8U A;  5AQS B;  5JR9 C;  2XAF B;  4DR4 T;  1UK5 A;  4YY3 T;  1HNW T;  3ZJ1 A;  4HGA A;  1KF6 A;  4WZX A;  3O1J A;  4JYA T;  2BKP A;  4A97 A;  3G06 A;  5JR9 B;  2BKN A;  4AIU A;  4GIW A;  4MLK A;  4IL9 A;  5CFB A;  4PJJ A;  1MMN A;  1HX8 A;  2ACZ A;  2ZM8 A;  5JH7 E;  3MJX A;  2V6Y B;  5L3E B;  3VKG A;  1SA0 E;  4WW0 A;  2N1G A;  3N9L A;  2V7M A;  2RA1 A;  3H3A A;  1V9D A;  2UUC T;  1MMG A;  3OYX A;  4U2Y A;  2BVL A;  5L3G B;  2W2U A;  2JQH A;  4LF4 T;  2WWV A;  1KNZ A;  1SUM B;  4JI8 T;  4H63 V;  1H7C A;  2XSB A;  1NEK A;  4H9P C;  3ETV A;  2UXD T;  1VCT A;  4QHO A;  4TN7 B;  5L3C B;  5HEH A;  4U72 A;  2CA5 A;  4A5X A;  3UUL A;  2IAK A;  4O8S A;  1ZHC A;  4HEA A;  5FNV E;  1OWA A;  3HR0 A;  5J0Z A;  1OXZ A;  3AXJ B;  2FUP A;  4AQF C;  2JQQ A;  5CJ5 A;  5DQW A;  3P4W A;  3HKB E;  5HEO A;  2VUR A;  3K8P C;  2JMK A;  3ZMS B;  2X9Y A;  4Z91 A;  4IL4 A;  1WRD A;  4UF0 B;  2WB5 A;  4B6X A;  4C91 A;  2NW9 A;  4IE5 A;  5LBQ B;  4IST A;  2BS3 A;  2H89 A;  4IDZ A;  4NUU A;  3UUM A;  1KK7 A;  1FMV A;  5CA0 E;  2X51 A;  2CEA A;  3RIF A;  4UEM A;  5AQK B;  5TAO A;  5ADX L;  4IGU A;  1YKE B;  2CXD A;  2A3D A;  2FJB A;  1HG5 A;  3C4X A;  3ZST A;  4KMC A;  4NXN T;  4LMJ A;  4UIG A;  2YDS A;  5HXR A;  2WMN A;  4PK6 A;  3MAC A;  5DJQ C;  5FMN A;  2MBG A;  4UR9 A;  5HEU A;  1QLB A;  2IC9 A;  1HX1 B;  3F57 A;  3N9O A;  1QUU A;  2D2S A;  5J2T E;  3OJA A;  5FY7 A;  3CQG B;  4YT0 A;  4ZI3 C;  3FBL A;  1R8I A;  2NTY A;  3IEE A;  2WU2 A;  2GK9 A;  2E9X A;  5JDH A;  3J9X 1;  3K3O A;  1YKH B;  2VQE T;  2WS3 A;  2X9X A;  2BG9 E;  2V6X A;  5AQL B;  2J47 A;  2JJ9 A;  4XAX B;  4MHC A;  2V6Y A;  3JCF A;  2OA5 A;  3NVO A;  2QRX A;  4HWD A;  3L8R A;  3AEC A;  3TKL B;  5AQQ B;  4ILA A;  4HFD A;  4TX5 A;  2K5B B;  1HFA A;  3RIA A;  1DU2 A;  2KWI B;  2KWH A;  2LEH A;  3UTK A;  4Z90 A;  4QX8 B;  2XZE A;  5LA6 E;  4BA9 A;  3M3Z B;  3P50 A;  1E7P A;  4IE6 A;  1T7S A;  2C5I T;  4HFV A;  2KND A;  4I50 E;  4AIS A;  4YHJ A;  2XQ5 A;  3DP7 A;  3AXJ A;  4IE0 A;  2LT3 A;  5FXZ A;  3ONX A;  2ZM2 A;  1WCR A;  4ZS3 A;  4P1N A;  4X1I E;  5AQV B;  1I94 T;  1W0A A;  2VL8 A;  3Q5E A;  2ACX A;  4NUV A;  1WFD A;  1N34 T;  4DR1 T;  5F8P A;  4G63 A;  2WU5 A;  3KBT A;  5JDQ A;  2M6B A;  3ANW B;  1HR0 T;  3ZYM A;  3FZH B;  2ODV A;  2C5K T;  2DWG A;  4JLE A;  3QB5 K;  2QA7 A;  3N9Q A;  3C51 A;  3QOF A;  4KX6 A;  4C90 A;  4AKL A;  2SPC A;  1VOM A;  3I0O A;  4U74 A;  2XUE A;  3C98 B;  3AEE A;  5AQN B;  4DV7 T;  3RH3 A;  5HXC A;  4UVC B;  3GWH A;  4LMK A;  3UQ4 A;  1FEW A;  3UU3 A;  1IBK T;  3RPU A;  2JQ9 A;  1J5W A;  5F3J A;  4LF6 T;  1IJ6 A;  3RYC E;  4JI0 T;  3NKZ A;  5LBM A;  2BDE A;  1E2A A;  2PJQ A;  2A72 A;  5IYZ E;  4ZHQ E;  3CX6 B;  4IDN A;  3NRX A;  4DR5 T;  4E7Z A;  2V1D B;  2DL1 A;  3NBX X;  3M65 A;  4HKA A;  4YHH T;  3RHW A;  3ZSS A;  3T8O A;  2LJL A;  4OYJ A;  5LB7 B;  3RRW A;  1OED E;  1KEY A;  4AKR B;  2FJD A;  4H9R C;  4HN9 A;  4U2Z A;  1L0V A;  1D1A A;  5KDM C;  3MK7 C;  2L8K A;  3F2E A;  3AE3 A;  2H3R A;  4DBQ A;  2K48 A;  3TLV A;  2CXL A;  5KXJ A;  1YQ4 A;  4HE8 A;  2BKO A;  3F31 A;  5JRC B;  3PUV F;  4QH5 A;  2LLY A;  4DND A;  1NWM X;  1NAF A;  3V5U A;  3MKD A;  1XMO T;  3KVA A;  2UXB T;  2FJA A;  4I0U A;  4YXD A;  5FXX A;  5M4Y A;  3P7I A;  4ZI7 E;  3CKD A;  3UU8 A;  4O2B E;  3EI0 A;  2LOP A;  2Y6X A;  3BK9 A;  3TLU A;  3WAJ A;  2NP9 A;  3SFD A;  1YXR A;  1QSD A;  4ZOL E;  3ANW A;  3W15 B;  2WQY A;  2CBJ A;  2WDQ A;  3GMI A;  3NZQ A;  3K3N A;  2CHO A;  3I9Y A;  5FL1 A;  3B13 A;  2VQF T;  2YU2 A;  3RQW A;  4ASK A;  3EUH A;  3SRZ A;  2WSS V;  1US7 B;  2XAS B;  1CUN A;  3PUY F;  4MBQ A;  1VCS A;  4DO0 A;  3UQ7 A;  2I0M A;  3AEB A;  4F8H A;  4HWI B;  4ZI2 D;  1UUR A;  3AA1 B;  4WNK A;  2CRB A;  3L09 A;  1YW0 A;  3AEF A;  4TV8 E;  1HF8 A;  3ONJ A;  4JI1 T;  4CN4 A;  2X0Y A;  2KLQ A;  3RIU C;  2MAW A;  3ZN1 B;  5FL0 A;  4EED A;  3AVR A;  4TWD A;  2AE9 A;  3KDS E;  2VKJ A;  2M67 A;  2IC6 A;  2Q9Q D;  3PUA A;  5C3J A;  4ADZ A;  4PJL A;  3OVU A;  3O1H A;  3LK2 B;  3FXE B;  3ABV A;  4UV9 B;  4NIQ A;  2VKO A;  4WBO A;  1MMA A;  2HHH T;  5AQF B;  3AE5 A;  2WZI A;  5HCM A;  2LKH A;  5ABF B;  3UU5 A;  3FZL B;  4L0R A;  2XSA A;  3MA9 A;  2KXP B;  3CK6 A;  2XQ7 A;  2RPA A;  2KSR A;  2ODU A;  4CI3 B;  2E9X D;  3AA7 B;  1T72 A;  3TLS A;  3VR9 A;  4OFZ A;  4KP3 C;  3UUX B;  2OLT A;  3N5L A;  3JC6 C;  4L9I A;  2XQ8 A;  3T1H T;  2X9W A;  4LF8 T;  4CN1 A;  1M62 A;  4JI3 T;  1G8X A;  3QB5 A;  4IHJ E;  4ISS A;  5AQG B;  2ZLY A;  1IAP A;  2CXF A;  2XQY A;  4F6R C;  4EGW A;  2HN2 A;  4CXY A;  4K0U A;  4OK0 A;  4K0K T;  3DTO A;  2BG9 C;  4EV6 A;  3NZP A;  3R6N A;  2BG9 B;  2WDR A;  4U7Y A;  3FHN A;  2F4V T;  1ZOY A;  3I9W A;  2KZ7 B;  5LXT E;  2YEV C;  2CWO A;  3H37 A;  4ZS2 A;  3IF8 B;  3ZEF B;  2X0H A;  5HXH A;  1D0Z A;  4AXP A;  4HTE A;  4QXB B;  2XAQ B;  2IML A;  2L3L A;  2V8S V;  4YFS A;  4A98 A;  4E7S A;  2PFV A;  2UUB T;  4AI6 A;  2CLY C;  2MOZ A;  5LYJ E;  3PUZ F;  2Q9Q A;  3GN5 B;  5E0O A;  2WDV A;  5ABE A;  4QKN A;  4JI7 T;  3SOL A;  5FVK A;  2CLY B;  3CWZ B;  5FY0 A;  3RI5 A;  3AE1 A;  1VRB A;  3RC3 A;  2VL0 A;  2X66 A;  2B76 A;  2LRL A;  2W63 A;  4TZ4 C;  2C0S A;  2XY8 B;  2EHO C;  1WYB A;  1XDO A;  3RKO A;  1HG2 A;  5HXS A;  5CB4 E;  5JR9 A;  3BQI A;  4DR7 T;  2EHO B;  2CPT A;  2IHR 1;  1BR4 A;  3RLF F;  5AQI B;  5ABG A;  4O4H E;  1IBL T;  4X5T A;  2C5J A;  3K1S A;  4XBF B;  2WP9 A;  5ABF A;  4U31 A;  3PUG A;  3QK6 A;  3RYF E;  4CZZ B;  2N9D A;  3N2G E;  4EZ4 A;  3B57 A;  3CQC B;  3SS1 A;  2W66 A;  2YIN A;  4LF9 T;  3PU8 A;  3P8C D;  2CHN A;  4ZZB A;  3UT5 E;  2YN6 A;  3AEA A;  5AQT B;  2HPJ A;  2XJ7 A;  2XAH B;  1FJG T;  3AE8 A;  4XZC A;  2DHR A;  3CQX C;  4JUY A;  2V5C A;  3RF1 A;  4DV3 T;  3ETU A;  3P4P A;  4O2A E;  1X79 A;  3C4Z A;  4IT4 A;  4CXX A;  2XAJ B;  5JDM A;  1JNR A;  4WBN E;  2LSJ A;  5L3F B;  1D1C A;  4H9N C;  4MFR A;  1X9B A;  2I6H A;  3RYH E;  5ETW A;  4TWF A;  2IDO B;  3O1I A;  3ZN0 B;  3CIR A;  5HCJ A;  4LFB T;  4PK5 A;  5LHI B;  5DQV A;  2BVM A;  4AQF A;  4UF0 A;  5FYM A;  3LG7 A;  2MYS A;  2W0G A;  3HL6 A;  1KFY A;  5J1G A;  2N2N A;  3AVS A;  5FP3 A;  5AQR B;  2FBW A;  5DAB A;  4G2A A;  2YU1 A;  4CI2 B;  1OED B;  3GN5 A;  1WLX A;  2P9B A;  3OKQ A;  3ZJ2 A;  2I59 A;  4IIJ E;  3VKH A;  5LCY A;  1MIW A;  2XPK A;  2X9H A;  4TWH A;  3Q5D A;  4DID B;  3VHL A;  2E8I A;  2NW7 A;  4GKK T;  5JDF A;  4ILC A;  4FJO A;  2X67 A;  3NRY A;  5EK3 A;  5FVL A;  3N2K E;  4U33 A;  2YKS A;  4QWN B;  1XDP A;  4DR3 T;  4PW8 A;  2XAG B;  5CGM A;  2EHO A;  3E0Z A;  4I55 E;  2WMO A;  4QX7 B;  3IA3 A;  3VU7 H;  4NXM T;  4AQY T;  3EAM A;  4AKH A;  4B3T T;  4QXC B;  3L39 A;  4ZXL A;  4J2C A;  2A2F X;  4UXN B;  2ZMA A;  4TV9 E;  3HKD E;  4O4J E;  4X65 T;  5BMV E;  4HWC A;  3UFE A;  2XQ6 A;  3IHR A;  2V5D A;  2CM0 A;  2W67 A;  2KT9 A;  1MNE A;  3O4X E;  2JQK A;  2UUA T;  2ES0 A;  2BS4 A;  2VK9 A;  4JI2 T;  5AQJ B;  3P4Q A;  3FZF B;  2VVS A;  2IUB A;  4O4L E;  2VB6 A;  4MAL A;  2CE7 A;  3AAE B;  2XM1 A;  2AXD S;  3OPC A;  4DR2 T;  3FXD B;  4UEL A;  5JVD E;  3LK3 B;  4GK0 E;  3UU6 A;  2WBL A;  5H6Q B;  3OBV E;  2H7O A;  3UUB A;  3AAI A;  2UXX B;  5LG3 A;  2WWU A;  2XQ3 A;  4YTN A;  4AQG A;  2LSY A;  2JIW A;  3PV0 F;  3JAD A;  3PUR A;  4X1Y E;  4HFH A;  5JRE A;  1SE7 A;  3N9P A;  3CX8 B;  2HN1 A;  2H88 A;  3T1Y T;  5LHH B;  2BBH A;  2XQ9 A;  2LSI A;  3AE2 A;  1HNX T;  2K3W A;  4KI0 F;  4PJM A;  5HYA A;  1ZV4 X;  4PFO A;  5H6R B;  4YSZ A;  3ZYK A;  4TNV A;  3PUQ A;  4X66 T;  1LKX A;  5LGU B;  3AB3 B;  4QXH B;  2E2A A;  2LRK A;  3H3M A;  3RQU A;  3KV4 A;  2RP4 A;  5AQH B;  4P0A A;  1U5P A;  2V7J A;  3DJB A;  2OV9 A;  1EZ3 A;  1T8B A;  3CPZ A;  3ZMT B;  2VKD A;  1CHU A;  2LM2 A;  3OYZ A;  4H9O C;  1MIY A;  2IIU A;  2LHR A;  2WCA A;  2BS2 A;  4X62 T;  5JTG A;  5IHY A;  1MMD A;  1D1B A;  2J62 A;  4ZZC A;  2A9U A;  3HI2 A;  4HFE A;  2LSK A;  4DVD A;  1KNP A;  2V7I A;  3Q5X A;  3EDV A;  1IZN B;  4DMW A;  5BR8 T;  1HTJ F;  2FJE A;  3BQK A;  3KVB A;  3RYI E;  3ZC0 A;  5JDG A;  3OTO T;  4YLH A;  2WZH A;  4ILU A;  3D0T A;  3Q5W A;  2E9X C;  5IUX A;  2NOX A;  4TUY E;  1W0B A;  1J5E T;  3B5M A;  1XZY A;  2LOS A;  5AFU L;  3ONL C;  5LHG B;  2E9X B;  1I6Z A;  2WAU A;  4CN6 A;  3N2O A;  2E5V A;  2XHE B;  4Z8X A;  1LVK A;  4Q25 A;  4ZEY A;  1N33 T;  2MTQ A; 
#chains in the Genus database with same CATH homology
 1M7K A;  3FZF B;  5AQU B;  1UK5 A;  3LDQ B;  4HWD A;  5AQN B;  5AQF B;  3FZH B;  4HWC A;  5AQK B;  5AQT B;  5AQM B;  4HWI B;  5AQO B;  1HX1 B;  5AQH B;  3FZM B;  1I6Z A;  3FZK B;  3FZL B;  4HWH A;  3M3Z B;  5AQQ B;  4HWF A;  5AQI B;  1UGO A;  2D9D A;  5AQL B;  5AQV B;  1T7S A;  1M62 A;  5AQR B;  5AQS B;  5AQG B;  3A8Y C;  5AQP B;  5AQJ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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