5AQQB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
111
structure length
106
Chain Sequence
SNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 44
structure length 106
sequence length 111
chains with identical sequence D, F
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqqB00
4HWHA 5AQHB 1UGOA 4HWDA 3FZKB 5AQKB 5AQUB 1M62A 5AQGB 3FZMB 1HX1B 2D9DA 1T7SA 3LDQB 5AQSB 4HWFA 1I6ZA 4HWIB 5AQIB 5AQOB 5AQPB 5AQTB 1M7KA 3FZLB 4HWCA 5AQNB 3FZFB 3A8YC 5AQQB 1UK5A 5AQRB 5AQMB 5AQVB 5AQLB 5AQJB 3M3ZB 5AQFB 3FZHB
chains in the Genus database with same CATH superfamily
4L0RA 1UGOA 2Z6EA 1HX1B 2IHR1 4ZOLE 3N9OA 2CXDA 2LM2A 4UV9B 3Q5XA 3FBZA 3WAKA 2FJBA 4YFSA 5FXWA 5CA0E 2IC6A 2LOSA 3CPZA 4YHJA 5JRCB 2CBJA 4J2CA 1XWMA 4AIUA 3UULA 4HKAA 2WQYA 4ZHQE 3ZCJA 2LOPA 2VKHA 2LHRA 1J5ET 3EVYA 2Q9QB 4A5XA 1FJGT 2WCAA 2PG8A 3I1AA 5BMVE 2KZ7B 2XHEB 3LFMA 2XASB 5LG3A 5FY7A 1IZNB 2VKDA 3AA7B 4DV5T 4KUMB 1CUNA 1IAPA 2XQ9A 4AXPA 3PU8A 1MIYA 5HWYA 1KFYA 1KNRA 2IAKA 1N36T 1MMNA 2EHOD 3ESLA 2QRXA 4HFDA 1HFAA 1WCRA 2Y48B 3RYFE 1FEWA 1OEDB 3O1HA 2E8IA 3FB2A 2UUBT 3UUNA 2JJ9A 5L3FB 2NW7A 2CA5A 2ODUA 4HWCA 1YW0A 2YU2A 5AQQB 3KVBA 2I6HA 3O1JA 1YKEB 4TNVA 1SUMB 3EUHA 3HKCE 3RYCE 3T8OA 4I4TE 4NPPA 4KX6A 4PK5A 4C90A 2IUBA 4E7SA 4OX9T 1IJ6A 1LVKA 1XMOT 3HKDE 3ZYMA 2KSRA 5JR9C 4PK4A 4GKJT 2V6YB 4HFIA 1YQ4A 3N5LA 3ZT5A 5L2LA 3OBVE 3ONJA 1ZKEA 1NAFA 1LKXA 4DV0T 4P09A 3OJAA 3I0OA 4QX8B 3FXEB 2VB6A 4IDPA 4UF0A 1VCTA 5LNKA 1FIOA 5H6RB 1KNPA 2H89A 4DR4T 1I6ZA 4LMLA 4XZCA 4FJOA 4ADZA 3AE8A 2W66A 1EZ3A 3JC6C 2WB5A 4YJ2E 2L8KA 4PJLA 2UXXB 4X1IE 3RLFF 3L8RA 4JI7T 2PFVA 3FZMB 3SFEA 5J2TE 2ODVA 1D0YA 1NENA 2QA7A 4DMVA 2A3DA 5FY1A 3QK6A 3KINB 5FL1A 4OYKA 4WBOA 2XTLA 3IHRA 4U33A 2EHOB 2PBIA 4YTMA 1W9RA 1M62A 4DUYT 3CQXC 4H9NC 2FJDA 4JI4T 5IWAT 1XMQT 1KNZA 2D5UA 2E9XA 4IDNA 3TLUA 2CEAA 1WR6A 2VURA 5FXXA 5KXJA 5ABGA 5L4HA 3ZMTB 4AI6A 3P4PA 3FHNA 4LF8T 4BAYB 3UT5E 2XQ3A 4BA9A 2CE7A 2XQ8A 3JC6D 2FBWA 4TWFA 3UFEA 2YDQA 5JDGA 4H9PC 5FKYA 4HFCA 1ZP0A 3PUWF 1Y01A 5AQTB 5DQVA 4CZZB 3P7IA 1S94A 3HI2A 2OA5A 5LGTB 3ZN1B 4IL4A 5JDMA 5IUXA 2D2SA 2LHNA 4GK5E 4YSXA 4H63H 2ACXA 4UIGA 3E08A 3AVRA 3C64A 3UU4A 5AQNB 1BR1A 2Q9QC 4ZI7E 2FJAA 4X65T 2ZM2A 3ZLIA 3ZMSB 4Q25A 2VVSA 3NZPA 4AKLA 3HR0A 3QNUA 2X68A 3KFWX 3NVOA 3PUVF 4KP3C 5FYMA 2LRKA 2D0UA 1US7B 2WP9A 4HTEA 4TV8E 4AKIA 3RIAA 3ZT6A 1L0VA 1T98A 5CJ5A 4X64T 2XQ4A 4E7ZA 4AQFA 2QVAA 3PUQA 2VL8A 3P4RA 3NBXX 4X1KE 2M67A 5FP3A 4DR3T 4ILCA 3K3OA 1GQEA 4U72A 4EYUA 1OEDC 3LSVA 5BR8T 3KBUA 4U2ZA 3PDYA 1VOMA 2BVLA 2XPKA 1LVFA 5FMNA 3AEEA 1MNDA 2M6IA 3UFGA 2BBHA 1B7TA 2XUEA 4KHPT 3JCFA 1KEYA 3B5MA 4JI3T 2DL1A 5LXTE 3KDSE 4U7YA 4JEHB 3JAEA 4LFCT 1WYCA 4ASKA 1V9DA 5FVLA 1VRBA 4G63A 3BQIA 3AB3B 5ABEA 2KWHA 2C0SA 5LBQB 2UUCT 4UVAB 4NIQA 1CHUA 1T8BA 2CPTA 4UVBB 5HEOA 3RYIE 1QLBA 1NEKA 3Q5WA 2WM9A 2YU1A 3AE7A 1T72A 4X62T 2BS3A 2P9BA 3ZJ1A 4AKHA 4EGWA 1H7CA 2V5CA 2CRBA 2LRLA 1G8XA 5CA1E 5LA6E 3NZQA 3UUXB 4QXHB 2DWKA 4JI6T 4ZXLA 4DMWA 2WU5A 5AQUB 3AXJA 4LF4T 4IE4A 3I9WA 2V7JA 3LBXA 2VWAA 1KF6A 1D0ZA 3RKOA 2X9XA 3C98B 5JQGE 2NP9A 5DABA 4ANJA 5AQHB 2W00A 4YHHT 3ZC1A 4NUUA 2LSJA 3ETUA 3SRZA 3AAEB 4I55E 2EHOC 1ZEEA 1WYBA 1N32T 5FY0A 1HNXT 1W0AA 3NKZA 5C2TA 4KMCA 1J5WA 5JDQA 5L3EB 2YINA 2ZMAA 2A72A 2K24A 4M1PA 2KLQA 3UTKA 5LJMA 3S4UA 2IC9A 4LF7T 2WZHA 3VR9A 5LGUB 5LYJE 4IHJE 3PJAJ 4X1YE 4JYAT 4EB6E 4GK0E 5JR9A 4DV7T 2A9UA 1Z8UA 1I94T 2C5JA 2MTQA 1D1BA 3TLTA 2X9WA 3ONLC 2C5KT 4MBQA 2LSIA 5DJQC 4JUYA 2V7KA 3GN5A 2Y8DA 1VCSA 4IE6A 4EAHA 4EOZB 1W09A 3OYZA 3UU6A 4YT0A 5E0OA 1YKHB 5L3BB 5EK4A 3ZMZB 3H3MA 3W15B 4DIDB 2ZM6T 3ANWA 4O4IE 2HPJA 5FVKA 3QB5K 2CHNA 5JH7E 4F8HA 2BBJA 4U7IA 3N9QA 4Z90A 4HFVA 2H7VC 2W2UA 3FBLA 3RQUA 2W67A 2J62A 1D1CA 2YN6A 4DV4T 4H9OC 2BG9B 5LHGB 3OKQA 2UXCT 1XDPA 2JQQA 1HNZT 2Y6XA 3CWZB 5A1LA 1Z0PA 4XBFB 3RIUC 2LKGA 5HEHA 3R84B 4L5GA 2XAJB 4PJMA 4YLHA 4DUZT 4UELA 5EK2A 4B3RT 2J1DG 5LMNT 1BR0A 2LLYA 4TZ4C 3V5UA 3ZYKA 1IBLT 2DLRA 4GIWA 5TAOA 5ABFB 4ILAA 2WDVA 3RRWA 3M65A 3O4XE 2F4VT 1O3XA 2L3LA 2CWOA 3E0ZA 3TLVA 3R6NA 2XQAA 1QUUA 2I0MA 2LJLA 5HCMA 3VHLA 2V26A 2XSBA 4HEAA 2XAGB 2R6GF 4HWFA 2K5BB 2WMNA 4NUVA 2X67A 4QXBB 5L3GB 2AE9A 3IA3A 1UX5A 2LSYA 1E1HB 2XAQB 4IL9A 2NW8A 4QKNA 3U3IA 4DV2T 1UX4A 3G06A 3MXZA 5HXHA 5HCJA 2CBIA 4U31A 4KHZF 3FZLB 3AA6B 2VASA 1OXZA 4A98A 4AKGA 3DP7A 5JRCA 4L9IA 4CN4A 3OPCA 1D1AA 4IDQA 2V5DA 3LJCA 5AQKB 3AEBA 2BKPA 3MA9A 4IDZA 5HEJA 3N9PA 4MHCA 4P0BA 4YXDA 3BK9A 4JBWF 4HFBA 4LF9T 4K0UA 4EZ4A 2B1EA 2Q9QA 5LBMA 5LB7B 2BS4A 3Q2MA 4GYRA 3CQCB 4DO0A 4ERRA 2XQ6A 4U2YA 1W0BA 3CMLA 2LT3A 3MK7C 1WR0A 4TX5A 3ZJ2A 4HWDA 4I0UA 3DJBA 4Z8XA 3P8CD 3AECA 5KDMC 1HTJF 1MIVA 4TWDA 3RF1A 3ZT7A 1HS7A 4LMJA 1UURA 4BJNA 5L4EA 1U5PA 2BG9E 1OEDA 1XNQT 5AFUL 2X9HA 5FXVA 5CB4E 3NRXA 4CXWA 3H3AA 1WRDA 4LFBT 2YDRA 2A2FX 4H9SE 3UU3A 4COFA 1HNWT 2W63A 4HGAA 4IE7A 2WU2A 3AEFA 3EHZA 3NWIA 4ZS3A 4F6RC 2UXNB 5JDHA 5DQWA 3SOLA 5LJNA 4BJMA 3AXJB 2QYWA 4TWHA 2CMRA 4O4HE 4C91A 4O4JE 3PE0A 4DR6T 3TKLB 3SWHA 4EYYR 2PTFA 1X9BA 3ZC0A 2UUAT 4CI1B 2SPCA 5F5WA 2V6YA 2V7LA 2CXLA 4PFPA 4XAXB 4JI0T 3O1IA 4U74A 3AA1B 2PJQA 2LE8A 1JNRA 3L39A 3LG7A 4HN9A 3VU7H 2K48A 3ZMVB 2YOEA 2AXDS 4DV6T 2LKHA 5C8YE 3UUBA 5C3JA 2DNXA 4MLKA 5HXRA 1WFDA 3PTRB 5AQJB 2XQ5A 3UQ4A 4DV3T 2MAWA 3ABVA 3I0QA 1MMAA 3T1HT 1XNRT 3AEDA 3PUSA 3N9NA 1AJ3A 2N1GA 2VQFT 3EDVA 5AQOB 2BG9C 3PUYF 2ZM0A 4LMKA 4IE0A 3VKHA 3C50A 3CK6A 2DHRA 3HKEE 2BVMA 3GN5B 4ZZBA 5H6QB 5AQIB 4AKRB 1M7KA 3QB5A 2WAUA 2JQ9A 2EHOA 1BR4A 1SA0E 4ZEYA 3L3PA 3L09A 5HEGA 1G73A 5AQFB 2J47A 4WW0A 4B3ST 1YD8G 4V1Av 2VKOA 3K3QC 5CGMA 3F31A 1LRZA 2VKJA 2HPLA 2WY2A 4DVDA 3PUZF 2IW5B 4JEUB 3C4ZA 5HYAA 4FI5A 3Q9DA 3AE6A 2V1DB 3RC3A 1MIWA 3P4WA 4NXNT 2KT9A 3E22E 2UXDT 2KMFA 2H3RA 4YY3T 4ILBA 4DNDA 4HFEA 4B3TT 4ZZCA 3GA8A 2QGSA 1UUSA 2LSKA 4CXXA 3OYXA 3EAMA 2DWGA 2C5IT 5LHIB 2V7IA 1YXRA 3K3NA 4PW8A 3O9XA 2UU9T 3T1YT 2DCFA 4JLEA 1HCIA 2JPFA 5FL0A 2WBLA 5GONE 2E5LT 2X0LB 3D0TA 2OLTA 4UEMA 3AAAB 4IIJE 2IDOB 3KV4A 2JQKA 4IGUA 5LCYA 5JDFA 4EV6A 3GWHA 2MOZA 3DTOA 3F57A 3AAIA 1UK5A 4PK6A 2XAFB 4OHFA 2KINB 2NR4A 3AE3A 2X9YA 3FZKB 4IREA 4AQYT 3RIUA 2MPKA 2OV9A 3OVUA 1DU2A 4UF0B 3PUAA 4PAGA 2W4XA 3MACA 2XSAA 2CM0A 5JVDE 2WMOA 4DBRA 4Z91A 5JTGA 3A5XA 5ADXL 5AQVB 4N78D 1HX8A 2JMHA 3IF8B 2W62A 3RIFA 2DI4A 4NXMT 5LG4A 4TN7B 4X66T 3CKDA 2X51A 3KVAA 1T7SA 3LDQB 5AQSB 1Y64B 2MYSA 3PU3A 2XJ7A 3ZN0B 2BDEA 2XY8B 2LSGA 2ES0A 4QH4A 3RGLA 5LOVE 4ZI3C 2KNDA 4I50E 1IJ5A 3OTOT 1D0XA 5FNVE 3LK2B 4EIWA 2XZEA 5AQGB 4JV5T 3LK3B 5HXSA 4CN1A 1U4QA 1IBMT 2XQ7A 3P50A 3RX6A 2E5VA 3N2GE 4G2AA 2RPAA 3IBPA 2E9XB 5L3CB 4GYSA 1E2AA 1MMGA 2XM1A 1XDOA 4QWNB 4O2AE 4DR7T 2KWIB 4OFZA 2WS3A 4YTNA 3C51A 4ISSA 2YEVC 3J9X1 3CVRA 2UXBT 3VRBA 1SE7A 2NTYA 3C4WA 4ZS2A 4ZI2C 1N34T 4JI8T 2FJEA 2G0UA 2WDRA 4HE8A 3K1SA 1N33T 3N2KE 3RH3A 4ZI3D 2BKOA 4I43B 2ZM8A 1ZOYA 2D9DA 5HXEA 5J1GA 4MFRA 4K0KT 4JI5T 4UXNB 2CXFA 3AEAA 3ONXA 3RRCA 2J4GA 2VL0A 3BQKA 2WWVA 3RYHE 3P4SA 3ZSTA 4UV8B 5KMGP 2NTXA 2GK9A 4HWIB 3V5SA 4QXCB 4JI2T 4B6XA 4KBMB 3AE2A 2WSSV 1HG5A 2HHHT 3ZMUB 5EZYE 3EDUA 4P0AA 1XZYA 3VRAA 4ZI2D 3AE1A 3AEGA 4CN6A 5CFBA 5ETWA 3P4QA 3VKGA 2YDSA 1ZV4X 4O2BE 2D0TA 4TNWA 3NRYA 5JREA 4QHOA 4YSZA 3HA4A 4YSYA 1UCUA 2L9QA 3VR8A 2VVNA 2XQYA 5LP6E 2CLYB 2N2NA 2CCQA 5EK3A 4HWHA 4PNIA 3RPUA 4PJNA 2KXPB 1X79A 1HF8A 3HKBE 4A56A 2LM9A 3ZYLA 2K9AA 3Q5DA 2IIUA 4ISTA 2VQET 4CI3B 3RKGA 3UQ7A 4H63V 3FZHB 5HAXA 1R8IA 3B57A 3KV6A 4OYJA 4IT4A 4CQIA 4YJ3E 3ZEFB 5AQRB 4LF6T 3PJAA 1OEDE 3ZKRA 1NWMX 2FUPA 5LGNB 4O8SA 1BR2A 3N9MA 5ABHA 3WAJA 3H37A 2BG9A 5AQPB 1WLXA 2RA1A 4OK0A 3SFDA 2HH7A 3A7MA 3JAFA 2RP4A 2W61A 2BKNA 4UR9A 4AQGA 3C4XA 2V6XA 3TLWA 3KV9A 2VK9A 2N9DA 5F8PA 3LBXB 3AA0B 4JI1T 2JIWA 5ABFA 4PFOA 3ZCIA 4IDOA 2JRKA 5J2UE 2H7OA 1MMDA 4YTPA 4WBNE 2WZIA 3FXDB 1YQ3A 3J7Yq 3KBTA 3F2EA 1HG2A 2XAHB 3ZPOA 5LHHB 4KI0F 4DR2T 3MKDA 2BS2A 3N9LA 4UVCB 4LFAT 2YKSA 2JMKA 5LMUT 4HFHA 5M4YA 4MALA 1E7PA 1OWAA 3MZKB 2E9XC 3RI5A 1JNZA 1HR0T 4TV9E 3X1DA 3M3ZB 2B76A 2BZBA 4PJJA 2V7MA 4DV1T 5HWXA 2ZLYA 4EXTA 5HXCA 4CXYA 3CIRA 2WDQA 4QH5A 4H9RC 3ZSSA 5JR9B 1QSDA 4B3MT 4AISA 2H88A 3PV0F 5AQLB 1KK7A 3PUXF 4DBQA 2E2AA 3CQGB 3ETVA 3AE5A 2HN1A 3I9YA 2NW9A 4EEBA 2M6BA 3WI3A 3EI0A 4U3CA 4GKKT 3QC9A 2Q9QD 3A8YC 3LK42 1S35A 3UUMA 4LF5T 5AQMB 4H9QC 2XM2A 3SS1A 2ACZA 2V8SV 5HEUA 2X0YA 3ANWB 1ZHCA 4EZHA 1MNEA 3QUJA 4QH1A 5J0ZA 5JDLA 5KX5E 3IEEA 1SHZC 2HN2A 3K8PC 3PURA 2E9XD 3RHWA 2IMLA 4WZXA 1FMVA 3CX7B 3BQLA 4DR5T 3KV5A 3AE4A 3RQWA 3Q5EA 3EABA 2X66A 4P1NA 3UU5A 3AE9A 5IHYA 5JDNA 4TUYE 2CHOA 3FZFB 3CX8B 3AVSA 4WNKA 5L3DB 4GOUA 5IYZE 2MBGA 2X0HA 5L47A 3GMIA 3TLSA 4CI2B 3MJXA 3UU8A 4IE5A 5FXZA 3RC8A 3HL6A 4QX7B 2JQHA 4WYVA 4AQFC 1IBKT 2NWBA 2WWUA 2K3WA 1FMWA 3PUGA 2YK0A 1J1JA 3N2OA 3QOFA 4X20E 4X5TA 3B13A 4A97A 4EEDA 2CWYA 2W0GA 4DR1T 4O4LE 3CX6B 2CLYC 2LEHA 2I59A 3U78A 2NOXA 5F3JA 4ILUA 3JADA
chains in the Genus database with same CATH topology
4HWHA 5AQHB 1UGOA 4HWDA 3FZKB 5AQKB 5AQUB 1M62A 5AQGB 3FZMB 1HX1B 2D9DA 1T7SA 3LDQB 5AQSB 4HWFA 1I6ZA 4HWIB 5AQIB 5AQOB 5AQPB 5AQTB 1M7KA 3FZLB 4HWCA 5AQNB 3FZFB 3A8YC 5AQQB 1UK5A 5AQRB 5AQMB 5AQVB 5AQLB 5AQJB 3M3ZB 5AQFB 3FZHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HWH A;  5AQH B;  1UGO A;  4HWD A;  3FZK B;  5AQK B;  5AQU B;  1M62 A;  5AQG B;  3FZM B;  1HX1 B;  2D9D A;  1T7S A;  3LDQ B;  5AQS B;  4HWF A;  1I6Z A;  4HWI B;  5AQI B;  5AQO B;  5AQP B;  5AQT B;  1M7K A;  3FZL B;  4HWC A;  5AQN B;  3FZF B;  3A8Y C;  5AQQ B;  1UK5 A;  5AQR B;  5AQM B;  5AQV B;  5AQL B;  5AQJ B;  3M3Z B;  5AQF B;  3FZH B; 
#chains in the Genus database with same CATH topology
 4L0R A;  1UGO A;  2Z6E A;  1HX1 B;  2IHR 1;  4ZOL E;  3N9O A;  2CXD A;  2LM2 A;  4UV9 B;  3Q5X A;  3FBZ A;  3WAK A;  2FJB A;  4YFS A;  5FXW A;  5CA0 E;  2IC6 A;  2LOS A;  3CPZ A;  4YHJ A;  5JRC B;  2CBJ A;  4J2C A;  1XWM A;  4AIU A;  3UUL A;  4HKA A;  2WQY A;  4ZHQ E;  3ZCJ A;  2LOP A;  2VKH A;  2LHR A;  1J5E T;  3EVY A;  2Q9Q B;  4A5X A;  1FJG T;  2WCA A;  2PG8 A;  3I1A A;  5BMV E;  2KZ7 B;  2XHE B;  3LFM A;  2XAS B;  5LG3 A;  5FY7 A;  1IZN B;  2VKD A;  3AA7 B;  4DV5 T;  4KUM B;  1CUN A;  1IAP A;  2XQ9 A;  4AXP A;  3PU8 A;  1MIY A;  5HWY A;  1KFY A;  1KNR A;  2IAK A;  1N36 T;  1MMN A;  2EHO D;  3ESL A;  2QRX A;  4HFD A;  1HFA A;  1WCR A;  2Y48 B;  3RYF E;  1FEW A;  1OED B;  3O1H A;  2E8I A;  3FB2 A;  2UUB T;  3UUN A;  2JJ9 A;  5L3F B;  2NW7 A;  2CA5 A;  2ODU A;  4HWC A;  1YW0 A;  2YU2 A;  5AQQ B;  3KVB A;  2I6H A;  3O1J A;  1YKE B;  4TNV A;  1SUM B;  3EUH A;  3HKC E;  3RYC E;  3T8O A;  4I4T E;  4NPP A;  4KX6 A;  4PK5 A;  4C90 A;  2IUB A;  4E7S A;  4OX9 T;  1IJ6 A;  1LVK A;  1XMO T;  3HKD E;  3ZYM A;  2KSR A;  5JR9 C;  4PK4 A;  4GKJ T;  2V6Y B;  4HFI A;  1YQ4 A;  3N5L A;  3ZT5 A;  5L2L A;  3OBV E;  3ONJ A;  1ZKE A;  1NAF A;  1LKX A;  4DV0 T;  4P09 A;  3OJA A;  3I0O A;  4QX8 B;  3FXE B;  2VB6 A;  4IDP A;  4UF0 A;  1VCT A;  5LNK A;  1FIO A;  5H6R B;  1KNP A;  2H89 A;  4DR4 T;  1I6Z A;  4LML A;  4XZC A;  4FJO A;  4ADZ A;  3AE8 A;  2W66 A;  1EZ3 A;  3JC6 C;  2WB5 A;  4YJ2 E;  2L8K A;  4PJL A;  2UXX B;  4X1I E;  3RLF F;  3L8R A;  4JI7 T;  2PFV A;  3FZM B;  3SFE A;  5J2T E;  2ODV A;  1D0Y A;  1NEN A;  2QA7 A;  4DMV A;  2A3D A;  5FY1 A;  3QK6 A;  3KIN B;  5FL1 A;  4OYK A;  4WBO A;  2XTL A;  3IHR A;  4U33 A;  2EHO B;  2PBI A;  4YTM A;  1W9R A;  1M62 A;  4DUY T;  3CQX C;  4H9N C;  2FJD A;  4JI4 T;  5IWA T;  1XMQ T;  1KNZ A;  2D5U A;  2E9X A;  4IDN A;  3TLU A;  2CEA A;  1WR6 A;  2VUR A;  5FXX A;  5KXJ A;  5ABG A;  5L4H A;  3ZMT B;  4AI6 A;  3P4P A;  3FHN A;  4LF8 T;  4BAY B;  3UT5 E;  2XQ3 A;  4BA9 A;  2CE7 A;  2XQ8 A;  3JC6 D;  2FBW A;  4TWF A;  3UFE A;  2YDQ A;  5JDG A;  4H9P C;  5FKY A;  4HFC A;  1ZP0 A;  3PUW F;  1Y01 A;  5AQT B;  5DQV A;  4CZZ B;  3P7I A;  1S94 A;  3HI2 A;  2OA5 A;  5LGT B;  3ZN1 B;  4IL4 A;  5JDM A;  5IUX A;  2D2S A;  2LHN A;  4GK5 E;  4YSX A;  4H63 H;  2ACX A;  4UIG A;  3E08 A;  3AVR A;  3C64 A;  3UU4 A;  5AQN B;  1BR1 A;  2Q9Q C;  4ZI7 E;  2FJA A;  4X65 T;  2ZM2 A;  3ZLI A;  3ZMS B;  4Q25 A;  2VVS A;  3NZP A;  4AKL A;  3HR0 A;  3QNU A;  2X68 A;  3KFW X;  3NVO A;  3PUV F;  4KP3 C;  5FYM A;  2LRK A;  2D0U A;  1US7 B;  2WP9 A;  4HTE A;  4TV8 E;  4AKI A;  3RIA A;  3ZT6 A;  1L0V A;  1T98 A;  5CJ5 A;  4X64 T;  2XQ4 A;  4E7Z A;  4AQF A;  2QVA A;  3PUQ A;  2VL8 A;  3P4R A;  3NBX X;  4X1K E;  2M67 A;  5FP3 A;  4DR3 T;  4ILC A;  3K3O A;  1GQE A;  4U72 A;  4EYU A;  1OED C;  3LSV A;  5BR8 T;  3KBU A;  4U2Z A;  3PDY A;  1VOM A;  2BVL A;  2XPK A;  1LVF A;  5FMN A;  3AEE A;  1MND A;  2M6I A;  3UFG A;  2BBH A;  1B7T A;  2XUE A;  4KHP T;  3JCF A;  1KEY A;  3B5M A;  4JI3 T;  2DL1 A;  5LXT E;  3KDS E;  4U7Y A;  4JEH B;  3JAE A;  4LFC T;  1WYC A;  4ASK A;  1V9D A;  5FVL A;  1VRB A;  4G63 A;  3BQI A;  3AB3 B;  5ABE A;  2KWH A;  2C0S A;  5LBQ B;  2UUC T;  4UVA B;  4NIQ A;  1CHU A;  1T8B A;  2CPT A;  4UVB B;  5HEO A;  3RYI E;  1QLB A;  1NEK A;  3Q5W A;  2WM9 A;  2YU1 A;  3AE7 A;  1T72 A;  4X62 T;  2BS3 A;  2P9B A;  3ZJ1 A;  4AKH A;  4EGW A;  1H7C A;  2V5C A;  2CRB A;  2LRL A;  1G8X A;  5CA1 E;  5LA6 E;  3NZQ A;  3UUX B;  4QXH B;  2DWK A;  4JI6 T;  4ZXL A;  4DMW A;  2WU5 A;  5AQU B;  3AXJ A;  4LF4 T;  4IE4 A;  3I9W A;  2V7J A;  3LBX A;  2VWA A;  1KF6 A;  1D0Z A;  3RKO A;  2X9X A;  3C98 B;  5JQG E;  2NP9 A;  5DAB A;  4ANJ A;  5AQH B;  2W00 A;  4YHH T;  3ZC1 A;  4NUU A;  2LSJ A;  3ETU A;  3SRZ A;  3AAE B;  4I55 E;  2EHO C;  1ZEE A;  1WYB A;  1N32 T;  5FY0 A;  1HNX T;  1W0A A;  3NKZ A;  5C2T A;  4KMC A;  1J5W A;  5JDQ A;  5L3E B;  2YIN A;  2ZMA A;  2A72 A;  2K24 A;  4M1P A;  2KLQ A;  3UTK A;  5LJM A;  3S4U A;  2IC9 A;  4LF7 T;  2WZH A;  3VR9 A;  5LGU B;  5LYJ E;  4IHJ E;  3PJA J;  4X1Y E;  4JYA T;  4EB6 E;  4GK0 E;  5JR9 A;  4DV7 T;  2A9U A;  1Z8U A;  1I94 T;  2C5J A;  2MTQ A;  1D1B A;  3TLT A;  2X9W A;  3ONL C;  2C5K T;  4MBQ A;  2LSI A;  5DJQ C;  4JUY A;  2V7K A;  3GN5 A;  2Y8D A;  1VCS A;  4IE6 A;  4EAH A;  4EOZ B;  1W09 A;  3OYZ A;  3UU6 A;  4YT0 A;  5E0O A;  1YKH B;  5L3B B;  5EK4 A;  3ZMZ B;  3H3M A;  3W15 B;  4DID B;  2ZM6 T;  3ANW A;  4O4I E;  2HPJ A;  5FVK A;  3QB5 K;  2CHN A;  5JH7 E;  4F8H A;  2BBJ A;  4U7I A;  3N9Q A;  4Z90 A;  4HFV A;  2H7V C;  2W2U A;  3FBL A;  3RQU A;  2W67 A;  2J62 A;  1D1C A;  2YN6 A;  4DV4 T;  4H9O C;  2BG9 B;  5LHG B;  3OKQ A;  2UXC T;  1XDP A;  2JQQ A;  1HNZ T;  2Y6X A;  3CWZ B;  5A1L A;  1Z0P A;  4XBF B;  3RIU C;  2LKG A;  5HEH A;  3R84 B;  4L5G A;  2XAJ B;  4PJM A;  4YLH A;  4DUZ T;  4UEL A;  5EK2 A;  4B3R T;  2J1D G;  5LMN T;  1BR0 A;  2LLY A;  4TZ4 C;  3V5U A;  3ZYK A;  1IBL T;  2DLR A;  4GIW A;  5TAO A;  5ABF B;  4ILA A;  2WDV A;  3RRW A;  3M65 A;  3O4X E;  2F4V T;  1O3X A;  2L3L A;  2CWO A;  3E0Z A;  3TLV A;  3R6N A;  2XQA A;  1QUU A;  2I0M A;  2LJL A;  5HCM A;  3VHL A;  2V26 A;  2XSB A;  4HEA A;  2XAG B;  2R6G F;  4HWF A;  2K5B B;  2WMN A;  4NUV A;  2X67 A;  4QXB B;  5L3G B;  2AE9 A;  3IA3 A;  1UX5 A;  2LSY A;  1E1H B;  2XAQ B;  4IL9 A;  2NW8 A;  4QKN A;  3U3I A;  4DV2 T;  1UX4 A;  3G06 A;  3MXZ A;  5HXH A;  5HCJ A;  2CBI A;  4U31 A;  4KHZ F;  3FZL B;  3AA6 B;  2VAS A;  1OXZ A;  4A98 A;  4AKG A;  3DP7 A;  5JRC A;  4L9I A;  4CN4 A;  3OPC A;  1D1A A;  4IDQ A;  2V5D A;  3LJC A;  5AQK B;  3AEB A;  2BKP A;  3MA9 A;  4IDZ A;  5HEJ A;  3N9P A;  4MHC A;  4P0B A;  4YXD A;  3BK9 A;  4JBW F;  4HFB A;  4LF9 T;  4K0U A;  4EZ4 A;  2B1E A;  2Q9Q A;  5LBM A;  5LB7 B;  2BS4 A;  3Q2M A;  4GYR A;  3CQC B;  4DO0 A;  4ERR A;  2XQ6 A;  4U2Y A;  1W0B A;  3CML A;  2LT3 A;  3MK7 C;  1WR0 A;  4TX5 A;  3ZJ2 A;  4HWD A;  4I0U A;  3DJB A;  4Z8X A;  3P8C D;  3AEC A;  5KDM C;  1HTJ F;  1MIV A;  4TWD A;  3RF1 A;  3ZT7 A;  1HS7 A;  4LMJ A;  1UUR A;  4BJN A;  5L4E A;  1U5P A;  2BG9 E;  1OED A;  1XNQ T;  5AFU L;  2X9H A;  5FXV A;  5CB4 E;  3NRX A;  4CXW A;  3H3A A;  1WRD A;  4LFB T;  2YDR A;  2A2F X;  4H9S E;  3UU3 A;  4COF A;  1HNW T;  2W63 A;  4HGA A;  4IE7 A;  2WU2 A;  3AEF A;  3EHZ A;  3NWI A;  4ZS3 A;  4F6R C;  2UXN B;  5JDH A;  5DQW A;  3SOL A;  5LJN A;  4BJM A;  3AXJ B;  2QYW A;  4TWH A;  2CMR A;  4O4H E;  4C91 A;  4O4J E;  3PE0 A;  4DR6 T;  3TKL B;  3SWH A;  4EYY R;  2PTF A;  1X9B A;  3ZC0 A;  2UUA T;  4CI1 B;  2SPC A;  5F5W A;  2V6Y A;  2V7L A;  2CXL A;  4PFP A;  4XAX B;  4JI0 T;  3O1I A;  4U74 A;  3AA1 B;  2PJQ A;  2LE8 A;  1JNR A;  3L39 A;  3LG7 A;  4HN9 A;  3VU7 H;  2K48 A;  3ZMV B;  2YOE A;  2AXD S;  4DV6 T;  2LKH A;  5C8Y E;  3UUB A;  5C3J A;  2DNX A;  4MLK A;  5HXR A;  1WFD A;  3PTR B;  5AQJ B;  2XQ5 A;  3UQ4 A;  4DV3 T;  2MAW A;  3ABV A;  3I0Q A;  1MMA A;  3T1H T;  1XNR T;  3AED A;  3PUS A;  3N9N A;  1AJ3 A;  2N1G A;  2VQF T;  3EDV A;  5AQO B;  2BG9 C;  3PUY F;  2ZM0 A;  4LMK A;  4IE0 A;  3VKH A;  3C50 A;  3CK6 A;  2DHR A;  3HKE E;  2BVM A;  3GN5 B;  4ZZB A;  5H6Q B;  5AQI B;  4AKR B;  1M7K A;  3QB5 A;  2WAU A;  2JQ9 A;  2EHO A;  1BR4 A;  1SA0 E;  4ZEY A;  3L3P A;  3L09 A;  5HEG A;  1G73 A;  5AQF B;  2J47 A;  4WW0 A;  4B3S T;  1YD8 G;  4V1A v;  2VKO A;  3K3Q C;  5CGM A;  3F31 A;  1LRZ A;  2VKJ A;  2HPL A;  2WY2 A;  4DVD A;  3PUZ F;  2IW5 B;  4JEU B;  3C4Z A;  5HYA A;  4FI5 A;  3Q9D A;  3AE6 A;  2V1D B;  3RC3 A;  1MIW A;  3P4W A;  4NXN T;  2KT9 A;  3E22 E;  2UXD T;  2KMF A;  2H3R A;  4YY3 T;  4ILB A;  4DND A;  4HFE A;  4B3T T;  4ZZC A;  3GA8 A;  2QGS A;  1UUS A;  2LSK A;  4CXX A;  3OYX A;  3EAM A;  2DWG A;  2C5I T;  5LHI B;  2V7I A;  1YXR A;  3K3N A;  4PW8 A;  3O9X A;  2UU9 T;  3T1Y T;  2DCF A;  4JLE A;  1HCI A;  2JPF A;  5FL0 A;  2WBL A;  5GON E;  2E5L T;  2X0L B;  3D0T A;  2OLT A;  4UEM A;  3AAA B;  4IIJ E;  2IDO B;  3KV4 A;  2JQK A;  4IGU A;  5LCY A;  5JDF A;  4EV6 A;  3GWH A;  2MOZ A;  3DTO A;  3F57 A;  3AAI A;  1UK5 A;  4PK6 A;  2XAF B;  4OHF A;  2KIN B;  2NR4 A;  3AE3 A;  2X9Y A;  3FZK B;  4IRE A;  4AQY T;  3RIU A;  2MPK A;  2OV9 A;  3OVU A;  1DU2 A;  4UF0 B;  3PUA A;  4PAG A;  2W4X A;  3MAC A;  2XSA A;  2CM0 A;  5JVD E;  2WMO A;  4DBR A;  4Z91 A;  5JTG A;  3A5X A;  5ADX L;  5AQV B;  4N78 D;  1HX8 A;  2JMH A;  3IF8 B;  2W62 A;  3RIF A;  2DI4 A;  4NXM T;  5LG4 A;  4TN7 B;  4X66 T;  3CKD A;  2X51 A;  3KVA A;  1T7S A;  3LDQ B;  5AQS B;  1Y64 B;  2MYS A;  3PU3 A;  2XJ7 A;  3ZN0 B;  2BDE A;  2XY8 B;  2LSG A;  2ES0 A;  4QH4 A;  3RGL A;  5LOV E;  4ZI3 C;  2KND A;  4I50 E;  1IJ5 A;  3OTO T;  1D0X A;  5FNV E;  3LK2 B;  4EIW A;  2XZE A;  5AQG B;  4JV5 T;  3LK3 B;  5HXS A;  4CN1 A;  1U4Q A;  1IBM T;  2XQ7 A;  3P50 A;  3RX6 A;  2E5V A;  3N2G E;  4G2A A;  2RPA A;  3IBP A;  2E9X B;  5L3C B;  4GYS A;  1E2A A;  1MMG A;  2XM1 A;  1XDO A;  4QWN B;  4O2A E;  4DR7 T;  2KWI B;  4OFZ A;  2WS3 A;  4YTN A;  3C51 A;  4ISS A;  2YEV C;  3J9X 1;  3CVR A;  2UXB T;  3VRB A;  1SE7 A;  2NTY A;  3C4W A;  4ZS2 A;  4ZI2 C;  1N34 T;  4JI8 T;  2FJE A;  2G0U A;  2WDR A;  4HE8 A;  3K1S A;  1N33 T;  3N2K E;  3RH3 A;  4ZI3 D;  2BKO A;  4I43 B;  2ZM8 A;  1ZOY A;  2D9D A;  5HXE A;  5J1G A;  4MFR A;  4K0K T;  4JI5 T;  4UXN B;  2CXF A;  3AEA A;  3ONX A;  3RRC A;  2J4G A;  2VL0 A;  3BQK A;  2WWV A;  3RYH E;  3P4S A;  3ZST A;  4UV8 B;  5KMG P;  2NTX A;  2GK9 A;  4HWI B;  3V5S A;  4QXC B;  4JI2 T;  4B6X A;  4KBM B;  3AE2 A;  2WSS V;  1HG5 A;  2HHH T;  3ZMU B;  5EZY E;  3EDU A;  4P0A A;  1XZY A;  3VRA A;  4ZI2 D;  3AE1 A;  3AEG A;  4CN6 A;  5CFB A;  5ETW A;  3P4Q A;  3VKG A;  2YDS A;  1ZV4 X;  4O2B E;  2D0T A;  4TNW A;  3NRY A;  5JRE A;  4QHO A;  4YSZ A;  3HA4 A;  4YSY A;  1UCU A;  2L9Q A;  3VR8 A;  2VVN A;  2XQY A;  5LP6 E;  2CLY B;  2N2N A;  2CCQ A;  5EK3 A;  4HWH A;  4PNI A;  3RPU A;  4PJN A;  2KXP B;  1X79 A;  1HF8 A;  3HKB E;  4A56 A;  2LM9 A;  3ZYL A;  2K9A A;  3Q5D A;  2IIU A;  4IST A;  2VQE T;  4CI3 B;  3RKG A;  3UQ7 A;  4H63 V;  3FZH B;  5HAX A;  1R8I A;  3B57 A;  3KV6 A;  4OYJ A;  4IT4 A;  4CQI A;  4YJ3 E;  3ZEF B;  5AQR B;  4LF6 T;  3PJA A;  1OED E;  3ZKR A;  1NWM X;  2FUP A;  5LGN B;  4O8S A;  1BR2 A;  3N9M A;  5ABH A;  3WAJ A;  3H37 A;  2BG9 A;  5AQP B;  1WLX A;  2RA1 A;  4OK0 A;  3SFD A;  2HH7 A;  3A7M A;  3JAF A;  2RP4 A;  2W61 A;  2BKN A;  4UR9 A;  4AQG A;  3C4X A;  2V6X A;  3TLW A;  3KV9 A;  2VK9 A;  2N9D A;  5F8P A;  3LBX B;  3AA0 B;  4JI1 T;  2JIW A;  5ABF A;  4PFO A;  3ZCI A;  4IDO A;  2JRK A;  5J2U E;  2H7O A;  1MMD A;  4YTP A;  4WBN E;  2WZI A;  3FXD B;  1YQ3 A;  3J7Y q;  3KBT A;  3F2E A;  1HG2 A;  2XAH B;  3ZPO A;  5LHH B;  4KI0 F;  4DR2 T;  3MKD A;  2BS2 A;  3N9L A;  4UVC B;  4LFA T;  2YKS A;  2JMK A;  5LMU T;  4HFH A;  5M4Y A;  4MAL A;  1E7P A;  1OWA A;  3MZK B;  2E9X C;  3RI5 A;  1JNZ A;  1HR0 T;  4TV9 E;  3X1D A;  3M3Z B;  2B76 A;  2BZB A;  4PJJ A;  2V7M A;  4DV1 T;  5HWX A;  2ZLY A;  4EXT A;  5HXC A;  4CXY A;  3CIR A;  2WDQ A;  4QH5 A;  4H9R C;  3ZSS A;  5JR9 B;  1QSD A;  4B3M T;  4AIS A;  2H88 A;  3PV0 F;  5AQL B;  1KK7 A;  3PUX F;  4DBQ A;  2E2A A;  3CQG B;  3ETV A;  3AE5 A;  2HN1 A;  3I9Y A;  2NW9 A;  4EEB A;  2M6B A;  3WI3 A;  3EI0 A;  4U3C A;  4GKK T;  3QC9 A;  2Q9Q D;  3A8Y C;  3LK4 2;  1S35 A;  3UUM A;  4LF5 T;  5AQM B;  4H9Q C;  2XM2 A;  3SS1 A;  2ACZ A;  2V8S V;  5HEU A;  2X0Y A;  3ANW B;  1ZHC A;  4EZH A;  1MNE A;  3QUJ A;  4QH1 A;  5J0Z A;  5JDL A;  5KX5 E;  3IEE A;  1SHZ C;  2HN2 A;  3K8P C;  3PUR A;  2E9X D;  3RHW A;  2IML A;  4WZX A;  1FMV A;  3CX7 B;  3BQL A;  4DR5 T;  3KV5 A;  3AE4 A;  3RQW A;  3Q5E A;  3EAB A;  2X66 A;  4P1N A;  3UU5 A;  3AE9 A;  5IHY A;  5JDN A;  4TUY E;  2CHO A;  3FZF B;  3CX8 B;  3AVS A;  4WNK A;  5L3D B;  4GOU A;  5IYZ E;  2MBG A;  2X0H A;  5L47 A;  3GMI A;  3TLS A;  4CI2 B;  3MJX A;  3UU8 A;  4IE5 A;  5FXZ A;  3RC8 A;  3HL6 A;  4QX7 B;  2JQH A;  4WYV A;  4AQF C;  1IBK T;  2NWB A;  2WWU A;  2K3W A;  1FMW A;  3PUG A;  2YK0 A;  1J1J A;  3N2O A;  3QOF A;  4X20 E;  4X5T A;  3B13 A;  4A97 A;  4EED A;  2CWY A;  2W0G A;  4DR1 T;  4O4L E;  3CX6 B;  2CLY C;  2LEH A;  2I59 A;  3U78 A;  2NOX A;  5F3J A;  4ILU A;  3JAD A; 
#chains in the Genus database with same CATH homology
 4HWH A;  5AQH B;  1UGO A;  4HWD A;  3FZK B;  5AQK B;  5AQU B;  1M62 A;  5AQG B;  3FZM B;  1HX1 B;  2D9D A;  1T7S A;  3LDQ B;  5AQS B;  4HWF A;  1I6Z A;  4HWI B;  5AQI B;  5AQO B;  5AQP B;  5AQT B;  1M7K A;  3FZL B;  4HWC A;  5AQN B;  3FZF B;  3A8Y C;  5AQQ B;  1UK5 A;  5AQR B;  5AQM B;  5AQV B;  5AQL B;  5AQJ B;  3M3Z B;  5AQF B;  3FZH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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