5AQSB

Fragment-based screening of hsp70 sheds light on the functional role of atp-binding site residues
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
113
structure length
113
Chain Sequence
LGSNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
pubmed doi rcsb
molecule tags Chaperone
source organism Homo sapiens
molecule keywords HEAT SHOCK COGNATE 71 KDA PROTEIN
total genus 44
structure length 113
sequence length 113
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02179 BAG BAG domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.120 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 BAG domain 5aqsB00
5AQGB 1UGOA 3FZLB 3LDQB 3FZHB 5AQMB 3FZKB 1HX1B 3A8YC 1I6ZA 5AQQB 1T7SA 4HWDA 4HWHA 5AQOB 5AQVB 5AQNB 3M3ZB 5AQFB 5AQLB 5AQUB 4HWIB 5AQTB 4HWCA 5AQHB 2D9DA 4HWFA 5AQJB 5AQKB 1M62A 5AQIB 5AQSB 3FZFB 3FZMB 1M7KA 1UK5A 5AQRB 5AQPB
chains in the Genus database with same CATH superfamily
3J7Yq 2NR4A 4AQGA 4ASKA 5J1GA 3VR9A 2IC6A 5LJNA 3BQIA 5JRCA 1MIVA 3ZJ1A 4ZS3A 2VL0A 4HKAA 5L4HA 3OYZA 2XQ7A 1LKXA 5L3DB 3OYXA 2X9YA 2NW7A 2DNXA 4ISSA 2MOZA 5FXWA 2D5UA 4BAYB 3SFEA 3HL6A 4YSYA 1XNRT 1Y64B 1UCUA 4PAGA 5AQVB 1SE7A 1HCIA 5LBQB 5JDQA 4G63A 4AXPA 2ACXA 1OXZA 3RRWA 2UXBT 1HNXT 2Z6EA 3RRCA 2W63A 4JI7T 4DNDA 3C51A 4X64T 3RIUA 4V1Av 2L3LA 3UFGA 2VKJA 3NRYA 3ZYMA 4ZXLA 5HXSA 1BR0A 3N9QA 4IREA 5AQUB 4XAXB 3C64A 3PJAJ 5J2TE 4NUVA 5CB4E 4A56A 3UU3A 2MAWA 4B6XA 4PJLA 2I6HA 4I4TE 1I6ZA 2XZEA 2E9XB 4AKLA 4AQFA 2WQYA 5L3BB 1E1HB 2LKHA 3LG7A 5AQKB 3I0OA 2X9WA 2VWAA 4DBRA 4QWNB 5L2LA 2VASA 3PUSA 3PUGA 1Z0PA 3JC6D 2WZIA 1T8BA 3V5SA 2WAUA 4ZI3C 4IDOA 3WI3A 2OA5A 4IT4A 4LMJA 1D0ZA 3EHZA 5C8YE 4OFZA 4U33A 4YHJA 3BQKA 3AAAB 3AA7B 5LGTB 1NEKA 4TZ4C 1FEWA 3KVAA 1WR6A 3K1SA 2X66A 4U31A 3I1AA 4NPPA 5AQTB 3ZYKA 2X51A 2YU1A 3PE0A 4U7IA 4IE4A 5M4YA 5LNKA 5LP6E 4JI5T 3ZMZB 3T1YT 3FZKB 3UU8A 1MMDA 4JV5T 3AE2A 1LVFA 2W66A 4M1PA 4AIUA 3QOFA 4H9NC 2JRKA 5LBMA 3O4XE 4X65T 3H3MA 4L0RA 5KDMC 4IE0A 2RA1A 5HEGA 1US7B 2XQAA 4JI1T 4LF9T 2LKGA 3RLFF 1HNWT 4NXMT 3D0TA 2NW9A 2Y8DA 2NWBA 4DBQA 4EB6E 2YDQA 2CM0A 2D0TA 3TKLB 2QGSA 3CQCB 2XSBA 4JI8T 2CXFA 3RKGA 5HEOA 2LSGA 2W00A 1KNZA 2Y48B 2A3DA 3AAEB 1MMNA 1W09A 1HF8A 2XQYA 3GN5A 4X20E 4EZ4A 4BJMA 2PFVA 2XSAA 1FMVA 5LA6E 4OYKA 5LGUB 1J5WA 3QUJA 4G2AA 2LSKA 3SRZA 2DWGA 4EGWA 1U4QA 3UU5A 4HFBA 2ACZA 3P4SA 4LF8T 1VRBA 2LM9A 2AE9A 1IZNB 2KWHA 5HEHA 3ZN0B 2EHOB 4COFA 4JEUB 2XY8B 3JADA 4FI5A 3JC6C 2E9XD 4QH5A 4HWHA 3IEEA 4QX8B 5HAXA 4ILAA 2BS4A 2W61A 1YQ4A 4PK5A 1XMQT 3O1IA 4GKJT 3UT5E 3F57A 3PUXF 3FZLB 4DR5T 4OYJA 4DV7T 3KV6A 4F6RC 3AECA 2C0SA 4C91A 1CUNA 2V6YA 4YTPA 1IBKT 4HWIB 3C4ZA 2NTYA 4DR2T 1VOMA 2M6IA 1D1AA 3KV4A 1MMGA 2WMOA 2LJLA 2N2NA 5L4EA 3CMLA 1LVKA 3X1DA 2NTXA 1N33T 5FY0A 4GK5E 4DUZT 3RC3A 5C3JA 2Q9QA 2XUEA 3NWIA 3QK6A 5FL1A 2XASB 5HXCA 4KX6A 5LHIB 1D0YA 3U3IA 3UTKA 3EDVA 2BG9A 3AEDA 4MFRA 2KNDA 4HEAA 3Q5WA 4ADZA 3CK6A 3G06A 4NIQA 2BKPA 1FMWA 2N1GA 4I43B 1UK5A 4YFSA 5L3EB 1I94T 4KHPT 4UF0B 1YKEB 2PG8A 4QXHB 3ZEFB 3P50A 1FIOA 2BBHA 4TWHA 3AE6A 4JI6T 4F8HA 2J1DG 3LK2B 2V7KA 2D0UA 2ODVA 2CMRA 5AQSB 3PTRB 2LHRA 1UGOA 3EAMA 2LSIA 4PW8A 3P7IA 5E0OA 4DUYT 3GA8A 4Q25A 3PUWF 3AAIA 3AE3A 1O3XA 3V5UA 2KZ7B 4UEMA 5DJQC 4JUYA 2KLQA 1UURA 4TUYE 2X0YA 4NUUA 1FJGT 1HNZT 2VVNA 2XAJB 2E9XC 2G0UA 2VB6A 2W67A 3GMIA 3ONLC 4P09A 4IDPA 4MLKA 3FBZA 5ABFB 2FUPA 2HPLA 2EHOD 5CFBA 2YN6A 2J62A 5LHGB 2DCFA 4CQIA 4WNKA 1UX4A 3N9OA 3ZMSB 2SPCA 2OV9A 2JMHA 2LSJA 3CVRA 3MZKB 1M62A 5HXHA 4MHCA 1XDOA 1NWMX 2XAGB 1WCRA 4YT0A 1IJ6A 3RQWA 4H9QC 3O1JA 3HKEE 4JI2T 3N2KE 2CE7A 5F8PA 2FJAA 5FL0A 4X66T 2WM9A 3PDYA 4KP3C 2VURA 5FP3A 2JJ9A 3VRAA 3RI5A 4YTMA 3ESLA 4IHJE 3OJAA 3QC9A 4YTNA 3SWHA 1WYBA 2VKDA 3ZYLA 2UXNB 3IBPA 2H7VC 2X9HA 2Y6XA 5IUXA 5A1LA 2KMFA 4H9PC 4AI6A 3ANWA 1QSDA 1MNDA 3HA4A 2XAQB 1DU2A 2UUBT 2IMLA 3I0QA 2CCQA 2KINB 4B3TT 3N2GE 4JI4T 5JRCB 4X5TA 3CPZA 1N32T 4OHFA 1V9DA 4YSXA 3PUYF 1WLXA 2X9XA 4UVBB 5FXXA 4B3RT 4A97A 4P0AA 4GKKT 1ZHCA 2V5CA 4EZHA 2HN2A 3CQGB 3RH3A 2B1EA 2KWIB 2H3RA 4DR1T 2K5BB 3RPUA 2MYSA 3LJCA 2BZBA 2JQ9A 3FHNA 4O8SA 2VL8A 3KBTA 3Q5DA 2DWKA 3RF1A 2WU5A 2WU2A 1SUMB 1QUUA 5FXVA 5FYMA 3QNUA 3M65A 2VQET 4HWFA 5H6QB 4YSZA 4LF6T 2EHOC 3HKCE 1WFDA 4YJ2E 4YXDA 2YINA 2V1DB 3VHLA 3Q2MA 5JH7E 1HG2A 3ZSSA 4E7ZA 3AXJA 2WMNA 4UELA 2JMKA 4AQYT 1W0AA 2DL1A 4EOZB 3Q9DA 3ZLIA 1OEDA 4O4IE 2WBLA 5JDMA 3AEGA 4CI1B 3QB5A 4JI3T 1ZKEA 4LMLA 2WWUA 4QH1A 1HFAA 3W15B 3RKOA 4LF4T 4WW0A 5AQNB 3C50A 1YXRA 3AEBA 4ZOLE 4OX9T 2MPKA 1ZEEA 4MBQA 4KUMB 1YQ3A 2I0MA 5LJMA 2ZM8A 3NZPA 4HFCA 3RIFA 3E08A 2XQ3A 1S35A 4JEHB 2H7OA 3SS1A 1E2AA 3F2EA 4ILUA 1D1BA 4U2ZA 1N36T 3UFEA 4GOUA 1MNEA 3AE5A 1M7KA 2GK9A 2FJBA 4XZCA 3CIRA 4CZZB 4EEBA 5AQMB 4DO0A 3A8YC 3LBXA 1UUSA 3EABA 3NBXX 4UV9B 1YKHB 1EZ3A 2HHHT 2CWYA 3CX6B 4I0UA 1GQEA 3AEFA 4QX7B 2WDVA 3PURA 3NVOA 3LK3B 2BVLA 4CI3B 4EXTA 5KMGP 3VKGA 4UR9A 3MK7C 3RQUA 4KMCA 1QLBA 2LE8A 4TNVA 3KFWX 5HYAA 4IL4A 2MTQA 2DLRA 3S4UA 3N9LA 4BJNA 4Z91A 1ZOYA 2WY2A 4QHOA 3F31A 2F4VT 2D9DA 5CGMA 1W0BA 3MA9A 4DVDA 3ZMTB 2A72A 5JR9A 1HG5A 3GN5B 4H9OC 5HXEA 4AKGA 3EI0A 3OPCA 2HPJA 1X9BA 2C5IT 2ODUA 5L47A 5ABGA 5AQHB 2B76A 4PK4A 2P9BA 2V6XA 3IF8B 3K8PC 4B3MT 3AE9A 3FBLA 2UUAT 3N9NA 5HCJA 4HFHA 2BKOA 4U3CA 2KXPB 5JTGA 3B57A 3WAJA 3NZQA 3B5MA 3ONJA 4UVCB 2XJ7A 2FJEA 4DV0T 2W62A 3EDUA 3MXZA 1IBMT 2X0LB 1XNQT 2BDEA 2LT3A 2K48A 2XQ5A 3A5XA 5L3CB 2JIWA 4UV8B 2CXLA 3L3PA 2UUCT 1L0VA 2V6YB 5HEUA 2W4XA 2LRLA 5CA1E 2BS3A 3ZT7A 4U7YA 4ZZCA 5ABEA 4H9SE 2CHOA 1ZP0A 2WP9A 2CEAA 2C5KT 2KSRA 2WZHA 4IGUA 2Q9QB 4U2YA 1XDPA 4LF7T 3P8CD 1G73A 4GIWA 1R8IA 3KDSE 5HEJA 4DV1T 2V7MA 2IC9A 5ABHA 3ZKRA 2BG9B 4MALA 3FXEB 3UUXB 2YDRA 4X1YE 1XZYA 4HWDA 2XM1A 3L09A 3P4RA 2M67A 2XQ4A 2YU2A 2E5VA 1HTJF 2LHNA 3RIUC 1IBLT 5EZYE 3B13A 4JBWF 4DV4T 4PJJA 3Q5EA 1T7SA 1KF6A 3L8RA 1NENA 2JPFA 4TV8E 3JCFA 3PUZF 5AQPB 3TLSA 1KNPA 2LM2A 3ONXA 5KX5E 3RIAA 3PU3A 2WCAA 5AQLB 2ZLYA 5CJ5A 5F5WA 4NXNT 3ZCIA 3CX8B 3GWHA 4AQFC 4PNIA 1S94A 4DV6T 4X62T 5LMUT 3JAEA 4EYUA 2L8KA 2WWVA 3I9WA 2YOEA 2XPKA 1B7TA 2CHNA 5J0ZA 4WBOA 3VR8A 3UQ7A 5FVKA 4GYRA 4L5GA 1MMAA 2OLTA 5F3JA 5HWYA 3PV0F 3CWZB 1BR2A 3AB3B 3RHWA 5LOVE 3TLTA 3J9X1 2V7LA 2NP9A 3DTOA 2J47A 3ZC1A 2CWOA 3OKQA 2UXDT 4E7SA 2VVSA 5LG4A 1U5PA 2I59A 2WS3A 4O4HE 4N78D 5HXRA 4QXBB 3RYHE 1WRDA 5JDGA 2UU9T 2LEHA 4XBFB 5TAOA 5JQGE 2C5JA 2PBIA 2Q9QD 4PJMA 3AVRA 2V5DA 4CXYA 3PUAA 2LOSA 4KI0F 3P4QA 5ETWA 1D1CA 1AJ3A 1JNRA 3ANWB 3ZJ2A 5AQJB 3N2OA 1Z8UA 3A7MA 3IA3A 3HKDE 3SFDA 4U72A 2CXDA 3RC8A 4ILBA 2W0GA 3RYIE 2V26A 5L3GB 2LOPA 1Y01A 4BA9A 2V7IA 4IIJE 3R6NA 3EUHA 4DV5T 2IAKA 2UXXB 3PJAA 5JDNA 3DP7A 2A2FX 4EYYR 4PFPA 5JR9C 4IDNA 5H6RB 2QA7A 2K9AA 3TLUA 3ZCJA 3TLVA 3KVBA 2PJQA 5EK3A 4O2BE 3H37A 2AXDS 1IAPA 3ETVA 4TWFA 1HX8A 5ADXL 4PFOA 2VQFT 3ETUA 2IDOB 2K3WA 4ISTA 2RP4A 2BG9E 1XMOT 3R84B 5EK2A 5LG3A 3AXJB 3AE7A 1WR0A 3FB2A 3C4WA 4AKHA 5JREA 3ZT6A 5JDHA 2XAHB 1OWAA 2ZMAA 2VK9A 5LB7B 1YW0A 3TLWA 2D2SA 3AEEA 4HN9A 4IE6A 2E9XA 1OEDB 3UU4A 5L3FB 3T8OA 4QH4A 3QB5K 3AVSA 1J1JA 3UUMA 2HN1A 3ZC0A 2FBWA 2IUBA 4TX5A 5FY1A 4YHHT 3Q5XA 1LRZA 4LMKA 3ZPOA 3AEAA 4B3ST 2IIUA 2Q9QC 2R6GF 2YKSA 4YY3T 1VCSA 2NOXA 2M6BA 4CN1A 2JQKA 4O2AE 4U74A 4CN4A 4IDZA 1NAFA 4KBMB 2BG9C 3LFMA 5LMNT 3HKBE 1BR4A 3HR0A 4HE8A 3UU6A 2BKNA 5DABA 4EIWA 2IHR1 1KNRA 4LFCT 3KINB 4CN6A 4H63H 1ZV4X 3BQLA 2H89A 4DR7T 4YJ3E 2L9QA 2DHRA 4YLHA 3LBXB 4GYSA 2LSYA 3P4PA 3E22E 4X1IE 3K3QC 2XQ8A 5C2TA 2JQHA 3N9PA 5HWXA 4P0BA 5AQQB 3M3ZB 5DQVA 1KEYA 3N5LA 2YK0A 4JYAT 5LCYA 2QVAA 2CBIA 3HI2A 3UULA 2LLYA 1D0XA 3AA1B 4AKIA 2ZM0A 3MJXA 3H3AA 4AKRB 4ANJA 4K0KT 5FKYA 3ZT5A 3ABVA 3WAKA 2A9UA 5JDFA 3FZMB 3KBUA 2HH7A 3RYFE 3C98B 3NRXA 1J5ET 2E8IA 3UQ4A 4O4LE 2V8SV 5JR9B 3FXDB 5AFUL 4H63V 1IJ5A 4KHZF 5IYZE 4DR3T 5JVDE 1XWMA 4P1NA 1G8XA 1N34T 4J2CA 4QXCB 5FXZA 2X0HA 5GONE 4PK6A 4PJNA 3C4XA 2EHOA 5FY7A 3OVUA 3N9MA 3E0ZA 2WB5A 5KXJA 3FZFB 5BR8T 4X1KE 4HFVA 3PU8A 3PUQA 2RPAA 2BS2A 3MKDA 4EEDA 4UIGA 4IL9A 4ZS2A 2CA5A 2E5LT 3AE4A 4HGAA 4JI0T 3RGLA 3I9YA 4A5XA 4TN7B 2ZM2A 5AQFB 2XM2A 3K3OA 2JQQA 4ZI2D 1KK7A 2CPTA 1JNZA 2CLYC 2YEVC 3MACA 4CXXA 1SA0E 3VRBA 1HX1B 3DJBA 2BVMA 2XTLA 2LRKA 5AQOB 4HFIA 3NKZA 2CRBA 1H7CA 4IDQA 2WDQA 2XHEB 5LGNB 3LK42 4ZEYA 2H88A 4O4JE 3ZMUB 1MIWA 2IW5B 4WZXA 3OTOT 5LYJE 5HCMA 4I50E 4ZHQE 1KFYA 1WYCA 3ZSTA 4C90A 1OEDE 3VKHA 2WSSV 4LFBT 1W9RA 4H9RC 3FZHB 3VU7H 2KT9A 2FJDA 4ILCA 2ZM6T 1HS7A 5FNVE 4Z8XA 4QKNA 4CI2B 3CX7B 4WYVA 3BK9A 4UF0A 4DMWA 4HFEA 2MBGA 4AISA 4HFDA 4K0UA 3EVYA 3P4WA 2NW8A 3AE1A 3PUVF 5DQWA 4UVAB 3SOLA 2WDRA 4IE7A 4TNWA 3AA0B 4DV2T 4LF5T 3U78A 4LFAT 3CKDA 3LSVA 4WBNE 4ZI7E 4DIDB 2ES0A 3ZMVB 2N9DA 2X68A 5LHHB 1OEDC 3KV9A 3ZN1B 3RYCE 4DR6T 1VCTA 2DI4A 2PTFA 4JLEA 2QRXA 4IE5A 5ABFA 4I55E 4UXNB 5FMNA 3RX6A 5IWAT 4DV3T 1CHUA 4ZI2C 4OK0A 2VKOA 3AA6B 3JAFA 2BBJA 3O9XA 4TWDA 4A98A 3UUBA 3LDQB 1YD8G 2QYWA 2X67A 5J2UE 4TV9E 1MIYA 2J4GA 1BR1A 5CA0E 5JDLA 5BMVE 5EK4A 4L9IA 4DR4T 2XQ6A 3CQXC 3L39A 2V7JA 2XQ9A 1E7PA 3T1HT 5FVLA 4GK0E 2K24A 5IHYA 3IHRA 3AE8A 4EAHA 2XAFB 1HR0T 4ZZBA 5AQIB 2YDSA 5AQGB 1UX5A 4CXWA 3OBVE 4EV6A 1T98A 3UUNA 3K3NA 2CLYB 5LXTE 4FJOA 2W2UA 2E2AA 2UXCT 4ZI3D 4DMVA 1SHZC 4ERRA 4HWCA 3O1HA 1X79A 3KV5A 4HTEA 4Z90A 1T72A 2VKHA 2CBJA 5AQRB
chains in the Genus database with same CATH topology
5AQGB 1UGOA 3FZLB 3LDQB 3FZHB 5AQMB 3FZKB 1HX1B 3A8YC 1I6ZA 5AQQB 1T7SA 4HWDA 4HWHA 5AQOB 5AQVB 5AQNB 3M3ZB 5AQFB 5AQLB 5AQUB 4HWIB 5AQTB 4HWCA 5AQHB 2D9DA 4HWFA 5AQJB 5AQKB 1M62A 5AQIB 5AQSB 3FZFB 3FZMB 1M7KA 1UK5A 5AQRB 5AQPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AQG B;  1UGO A;  3FZL B;  3LDQ B;  3FZH B;  5AQM B;  3FZK B;  1HX1 B;  3A8Y C;  1I6Z A;  5AQQ B;  1T7S A;  4HWD A;  4HWH A;  5AQO B;  5AQV B;  5AQN B;  3M3Z B;  5AQF B;  5AQL B;  5AQU B;  4HWI B;  5AQT B;  4HWC A;  5AQH B;  2D9D A;  4HWF A;  5AQJ B;  5AQK B;  1M62 A;  5AQI B;  5AQS B;  3FZF B;  3FZM B;  1M7K A;  1UK5 A;  5AQR B;  5AQP B; 
#chains in the Genus database with same CATH topology
 3J7Y q;  2NR4 A;  4AQG A;  4ASK A;  5J1G A;  3VR9 A;  2IC6 A;  5LJN A;  3BQI A;  5JRC A;  1MIV A;  3ZJ1 A;  4ZS3 A;  2VL0 A;  4HKA A;  5L4H A;  3OYZ A;  2XQ7 A;  1LKX A;  5L3D B;  3OYX A;  2X9Y A;  2NW7 A;  2DNX A;  4ISS A;  2MOZ A;  5FXW A;  2D5U A;  4BAY B;  3SFE A;  3HL6 A;  4YSY A;  1XNR T;  1Y64 B;  1UCU A;  4PAG A;  5AQV B;  1SE7 A;  1HCI A;  5LBQ B;  5JDQ A;  4G63 A;  4AXP A;  2ACX A;  1OXZ A;  3RRW A;  2UXB T;  1HNX T;  2Z6E A;  3RRC A;  2W63 A;  4JI7 T;  4DND A;  3C51 A;  4X64 T;  3RIU A;  4V1A v;  2L3L A;  3UFG A;  2VKJ A;  3NRY A;  3ZYM A;  4ZXL A;  5HXS A;  1BR0 A;  3N9Q A;  4IRE A;  5AQU B;  4XAX B;  3C64 A;  3PJA J;  5J2T E;  4NUV A;  5CB4 E;  4A56 A;  3UU3 A;  2MAW A;  4B6X A;  4PJL A;  2I6H A;  4I4T E;  1I6Z A;  2XZE A;  2E9X B;  4AKL A;  4AQF A;  2WQY A;  5L3B B;  1E1H B;  2LKH A;  3LG7 A;  5AQK B;  3I0O A;  2X9W A;  2VWA A;  4DBR A;  4QWN B;  5L2L A;  2VAS A;  3PUS A;  3PUG A;  1Z0P A;  3JC6 D;  2WZI A;  1T8B A;  3V5S A;  2WAU A;  4ZI3 C;  4IDO A;  3WI3 A;  2OA5 A;  4IT4 A;  4LMJ A;  1D0Z A;  3EHZ A;  5C8Y E;  4OFZ A;  4U33 A;  4YHJ A;  3BQK A;  3AAA B;  3AA7 B;  5LGT B;  1NEK A;  4TZ4 C;  1FEW A;  3KVA A;  1WR6 A;  3K1S A;  2X66 A;  4U31 A;  3I1A A;  4NPP A;  5AQT B;  3ZYK A;  2X51 A;  2YU1 A;  3PE0 A;  4U7I A;  4IE4 A;  5M4Y A;  5LNK A;  5LP6 E;  4JI5 T;  3ZMZ B;  3T1Y T;  3FZK B;  3UU8 A;  1MMD A;  4JV5 T;  3AE2 A;  1LVF A;  2W66 A;  4M1P A;  4AIU A;  3QOF A;  4H9N C;  2JRK A;  5LBM A;  3O4X E;  4X65 T;  3H3M A;  4L0R A;  5KDM C;  4IE0 A;  2RA1 A;  5HEG A;  1US7 B;  2XQA A;  4JI1 T;  4LF9 T;  2LKG A;  3RLF F;  1HNW T;  4NXM T;  3D0T A;  2NW9 A;  2Y8D A;  2NWB A;  4DBQ A;  4EB6 E;  2YDQ A;  2CM0 A;  2D0T A;  3TKL B;  2QGS A;  3CQC B;  2XSB A;  4JI8 T;  2CXF A;  3RKG A;  5HEO A;  2LSG A;  2W00 A;  1KNZ A;  2Y48 B;  2A3D A;  3AAE B;  1MMN A;  1W09 A;  1HF8 A;  2XQY A;  3GN5 A;  4X20 E;  4EZ4 A;  4BJM A;  2PFV A;  2XSA A;  1FMV A;  5LA6 E;  4OYK A;  5LGU B;  1J5W A;  3QUJ A;  4G2A A;  2LSK A;  3SRZ A;  2DWG A;  4EGW A;  1U4Q A;  3UU5 A;  4HFB A;  2ACZ A;  3P4S A;  4LF8 T;  1VRB A;  2LM9 A;  2AE9 A;  1IZN B;  2KWH A;  5HEH A;  3ZN0 B;  2EHO B;  4COF A;  4JEU B;  2XY8 B;  3JAD A;  4FI5 A;  3JC6 C;  2E9X D;  4QH5 A;  4HWH A;  3IEE A;  4QX8 B;  5HAX A;  4ILA A;  2BS4 A;  2W61 A;  1YQ4 A;  4PK5 A;  1XMQ T;  3O1I A;  4GKJ T;  3UT5 E;  3F57 A;  3PUX F;  3FZL B;  4DR5 T;  4OYJ A;  4DV7 T;  3KV6 A;  4F6R C;  3AEC A;  2C0S A;  4C91 A;  1CUN A;  2V6Y A;  4YTP A;  1IBK T;  4HWI B;  3C4Z A;  2NTY A;  4DR2 T;  1VOM A;  2M6I A;  1D1A A;  3KV4 A;  1MMG A;  2WMO A;  2LJL A;  2N2N A;  5L4E A;  3CML A;  1LVK A;  3X1D A;  2NTX A;  1N33 T;  5FY0 A;  4GK5 E;  4DUZ T;  3RC3 A;  5C3J A;  2Q9Q A;  2XUE A;  3NWI A;  3QK6 A;  5FL1 A;  2XAS B;  5HXC A;  4KX6 A;  5LHI B;  1D0Y A;  3U3I A;  3UTK A;  3EDV A;  2BG9 A;  3AED A;  4MFR A;  2KND A;  4HEA A;  3Q5W A;  4ADZ A;  3CK6 A;  3G06 A;  4NIQ A;  2BKP A;  1FMW A;  2N1G A;  4I43 B;  1UK5 A;  4YFS A;  5L3E B;  1I94 T;  4KHP T;  4UF0 B;  1YKE B;  2PG8 A;  4QXH B;  3ZEF B;  3P50 A;  1FIO A;  2BBH A;  4TWH A;  3AE6 A;  4JI6 T;  4F8H A;  2J1D G;  3LK2 B;  2V7K A;  2D0U A;  2ODV A;  2CMR A;  5AQS B;  3PTR B;  2LHR A;  1UGO A;  3EAM A;  2LSI A;  4PW8 A;  3P7I A;  5E0O A;  4DUY T;  3GA8 A;  4Q25 A;  3PUW F;  3AAI A;  3AE3 A;  1O3X A;  3V5U A;  2KZ7 B;  4UEM A;  5DJQ C;  4JUY A;  2KLQ A;  1UUR A;  4TUY E;  2X0Y A;  4NUU A;  1FJG T;  1HNZ T;  2VVN A;  2XAJ B;  2E9X C;  2G0U A;  2VB6 A;  2W67 A;  3GMI A;  3ONL C;  4P09 A;  4IDP A;  4MLK A;  3FBZ A;  5ABF B;  2FUP A;  2HPL A;  2EHO D;  5CFB A;  2YN6 A;  2J62 A;  5LHG B;  2DCF A;  4CQI A;  4WNK A;  1UX4 A;  3N9O A;  3ZMS B;  2SPC A;  2OV9 A;  2JMH A;  2LSJ A;  3CVR A;  3MZK B;  1M62 A;  5HXH A;  4MHC A;  1XDO A;  1NWM X;  2XAG B;  1WCR A;  4YT0 A;  1IJ6 A;  3RQW A;  4H9Q C;  3O1J A;  3HKE E;  4JI2 T;  3N2K E;  2CE7 A;  5F8P A;  2FJA A;  5FL0 A;  4X66 T;  2WM9 A;  3PDY A;  4KP3 C;  2VUR A;  5FP3 A;  2JJ9 A;  3VRA A;  3RI5 A;  4YTM A;  3ESL A;  4IHJ E;  3OJA A;  3QC9 A;  4YTN A;  3SWH A;  1WYB A;  2VKD A;  3ZYL A;  2UXN B;  3IBP A;  2H7V C;  2X9H A;  2Y6X A;  5IUX A;  5A1L A;  2KMF A;  4H9P C;  4AI6 A;  3ANW A;  1QSD A;  1MND A;  3HA4 A;  2XAQ B;  1DU2 A;  2UUB T;  2IML A;  3I0Q A;  2CCQ A;  2KIN B;  4B3T T;  3N2G E;  4JI4 T;  5JRC B;  4X5T A;  3CPZ A;  1N32 T;  4OHF A;  1V9D A;  4YSX A;  3PUY F;  1WLX A;  2X9X A;  4UVB B;  5FXX A;  4B3R T;  4A97 A;  4P0A A;  4GKK T;  1ZHC A;  2V5C A;  4EZH A;  2HN2 A;  3CQG B;  3RH3 A;  2B1E A;  2KWI B;  2H3R A;  4DR1 T;  2K5B B;  3RPU A;  2MYS A;  3LJC A;  2BZB A;  2JQ9 A;  3FHN A;  4O8S A;  2VL8 A;  3KBT A;  3Q5D A;  2DWK A;  3RF1 A;  2WU5 A;  2WU2 A;  1SUM B;  1QUU A;  5FXV A;  5FYM A;  3QNU A;  3M65 A;  2VQE T;  4HWF A;  5H6Q B;  4YSZ A;  4LF6 T;  2EHO C;  3HKC E;  1WFD A;  4YJ2 E;  4YXD A;  2YIN A;  2V1D B;  3VHL A;  3Q2M A;  5JH7 E;  1HG2 A;  3ZSS A;  4E7Z A;  3AXJ A;  2WMN A;  4UEL A;  2JMK A;  4AQY T;  1W0A A;  2DL1 A;  4EOZ B;  3Q9D A;  3ZLI A;  1OED A;  4O4I E;  2WBL A;  5JDM A;  3AEG A;  4CI1 B;  3QB5 A;  4JI3 T;  1ZKE A;  4LML A;  2WWU A;  4QH1 A;  1HFA A;  3W15 B;  3RKO A;  4LF4 T;  4WW0 A;  5AQN B;  3C50 A;  1YXR A;  3AEB A;  4ZOL E;  4OX9 T;  2MPK A;  1ZEE A;  4MBQ A;  4KUM B;  1YQ3 A;  2I0M A;  5LJM A;  2ZM8 A;  3NZP A;  4HFC A;  3RIF A;  3E08 A;  2XQ3 A;  1S35 A;  4JEH B;  2H7O A;  3SS1 A;  1E2A A;  3F2E A;  4ILU A;  1D1B A;  4U2Z A;  1N36 T;  3UFE A;  4GOU A;  1MNE A;  3AE5 A;  1M7K A;  2GK9 A;  2FJB A;  4XZC A;  3CIR A;  4CZZ B;  4EEB A;  5AQM B;  4DO0 A;  3A8Y C;  3LBX A;  1UUS A;  3EAB A;  3NBX X;  4UV9 B;  1YKH B;  1EZ3 A;  2HHH T;  2CWY A;  3CX6 B;  4I0U A;  1GQE A;  3AEF A;  4QX7 B;  2WDV A;  3PUR A;  3NVO A;  3LK3 B;  2BVL A;  4CI3 B;  4EXT A;  5KMG P;  3VKG A;  4UR9 A;  3MK7 C;  3RQU A;  4KMC A;  1QLB A;  2LE8 A;  4TNV A;  3KFW X;  5HYA A;  4IL4 A;  2MTQ A;  2DLR A;  3S4U A;  3N9L A;  4BJN A;  4Z91 A;  1ZOY A;  2WY2 A;  4QHO A;  3F31 A;  2F4V T;  2D9D A;  5CGM A;  1W0B A;  3MA9 A;  4DVD A;  3ZMT B;  2A72 A;  5JR9 A;  1HG5 A;  3GN5 B;  4H9O C;  5HXE A;  4AKG A;  3EI0 A;  3OPC A;  2HPJ A;  1X9B A;  2C5I T;  2ODU A;  5L47 A;  5ABG A;  5AQH B;  2B76 A;  4PK4 A;  2P9B A;  2V6X A;  3IF8 B;  3K8P C;  4B3M T;  3AE9 A;  3FBL A;  2UUA T;  3N9N A;  5HCJ A;  4HFH A;  2BKO A;  4U3C A;  2KXP B;  5JTG A;  3B57 A;  3WAJ A;  3NZQ A;  3B5M A;  3ONJ A;  4UVC B;  2XJ7 A;  2FJE A;  4DV0 T;  2W62 A;  3EDU A;  3MXZ A;  1IBM T;  2X0L B;  1XNQ T;  2BDE A;  2LT3 A;  2K48 A;  2XQ5 A;  3A5X A;  5L3C B;  2JIW A;  4UV8 B;  2CXL A;  3L3P A;  2UUC T;  1L0V A;  2V6Y B;  5HEU A;  2W4X A;  2LRL A;  5CA1 E;  2BS3 A;  3ZT7 A;  4U7Y A;  4ZZC A;  5ABE A;  4H9S E;  2CHO A;  1ZP0 A;  2WP9 A;  2CEA A;  2C5K T;  2KSR A;  2WZH A;  4IGU A;  2Q9Q B;  4U2Y A;  1XDP A;  4LF7 T;  3P8C D;  1G73 A;  4GIW A;  1R8I A;  3KDS E;  5HEJ A;  4DV1 T;  2V7M A;  2IC9 A;  5ABH A;  3ZKR A;  2BG9 B;  4MAL A;  3FXE B;  3UUX B;  2YDR A;  4X1Y E;  1XZY A;  4HWD A;  2XM1 A;  3L09 A;  3P4R A;  2M67 A;  2XQ4 A;  2YU2 A;  2E5V A;  1HTJ F;  2LHN A;  3RIU C;  1IBL T;  5EZY E;  3B13 A;  4JBW F;  4DV4 T;  4PJJ A;  3Q5E A;  1T7S A;  1KF6 A;  3L8R A;  1NEN A;  2JPF A;  4TV8 E;  3JCF A;  3PUZ F;  5AQP B;  3TLS A;  1KNP A;  2LM2 A;  3ONX A;  5KX5 E;  3RIA A;  3PU3 A;  2WCA A;  5AQL B;  2ZLY A;  5CJ5 A;  5F5W A;  4NXN T;  3ZCI A;  3CX8 B;  3GWH A;  4AQF C;  4PNI A;  1S94 A;  4DV6 T;  4X62 T;  5LMU T;  3JAE A;  4EYU A;  2L8K A;  2WWV A;  3I9W A;  2YOE A;  2XPK A;  1B7T A;  2CHN A;  5J0Z A;  4WBO A;  3VR8 A;  3UQ7 A;  5FVK A;  4GYR A;  4L5G A;  1MMA A;  2OLT A;  5F3J A;  5HWY A;  3PV0 F;  3CWZ B;  1BR2 A;  3AB3 B;  3RHW A;  5LOV E;  3TLT A;  3J9X 1;  2V7L A;  2NP9 A;  3DTO A;  2J47 A;  3ZC1 A;  2CWO A;  3OKQ A;  2UXD T;  4E7S A;  2VVS A;  5LG4 A;  1U5P A;  2I59 A;  2WS3 A;  4O4H E;  4N78 D;  5HXR A;  4QXB B;  3RYH E;  1WRD A;  5JDG A;  2UU9 T;  2LEH A;  4XBF B;  5TAO A;  5JQG E;  2C5J A;  2PBI A;  2Q9Q D;  4PJM A;  3AVR A;  2V5D A;  4CXY A;  3PUA A;  2LOS A;  4KI0 F;  3P4Q A;  5ETW A;  1D1C A;  1AJ3 A;  1JNR A;  3ANW B;  3ZJ2 A;  5AQJ B;  3N2O A;  1Z8U A;  3A7M A;  3IA3 A;  3HKD E;  3SFD A;  4U72 A;  2CXD A;  3RC8 A;  4ILB A;  2W0G A;  3RYI E;  2V26 A;  5L3G B;  2LOP A;  1Y01 A;  4BA9 A;  2V7I A;  4IIJ E;  3R6N A;  3EUH A;  4DV5 T;  2IAK A;  2UXX B;  3PJA A;  5JDN A;  3DP7 A;  2A2F X;  4EYY R;  4PFP A;  5JR9 C;  4IDN A;  5H6R B;  2QA7 A;  2K9A A;  3TLU A;  3ZCJ A;  3TLV A;  3KVB A;  2PJQ A;  5EK3 A;  4O2B E;  3H37 A;  2AXD S;  1IAP A;  3ETV A;  4TWF A;  1HX8 A;  5ADX L;  4PFO A;  2VQF T;  3ETU A;  2IDO B;  2K3W A;  4IST A;  2RP4 A;  2BG9 E;  1XMO T;  3R84 B;  5EK2 A;  5LG3 A;  3AXJ B;  3AE7 A;  1WR0 A;  3FB2 A;  3C4W A;  4AKH A;  5JRE A;  3ZT6 A;  5JDH A;  2XAH B;  1OWA A;  2ZMA A;  2VK9 A;  5LB7 B;  1YW0 A;  3TLW A;  2D2S A;  3AEE A;  4HN9 A;  4IE6 A;  2E9X A;  1OED B;  3UU4 A;  5L3F B;  3T8O A;  4QH4 A;  3QB5 K;  3AVS A;  1J1J A;  3UUM A;  2HN1 A;  3ZC0 A;  2FBW A;  2IUB A;  4TX5 A;  5FY1 A;  4YHH T;  3Q5X A;  1LRZ A;  4LMK A;  3ZPO A;  3AEA A;  4B3S T;  2IIU A;  2Q9Q C;  2R6G F;  2YKS A;  4YY3 T;  1VCS A;  2NOX A;  2M6B A;  4CN1 A;  2JQK A;  4O2A E;  4U74 A;  4CN4 A;  4IDZ A;  1NAF A;  4KBM B;  2BG9 C;  3LFM A;  5LMN T;  3HKB E;  1BR4 A;  3HR0 A;  4HE8 A;  3UU6 A;  2BKN A;  5DAB A;  4EIW A;  2IHR 1;  1KNR A;  4LFC T;  3KIN B;  4CN6 A;  4H63 H;  1ZV4 X;  3BQL A;  2H89 A;  4DR7 T;  4YJ3 E;  2L9Q A;  2DHR A;  4YLH A;  3LBX B;  4GYS A;  2LSY A;  3P4P A;  3E22 E;  4X1I E;  3K3Q C;  2XQ8 A;  5C2T A;  2JQH A;  3N9P A;  5HWX A;  4P0B A;  5AQQ B;  3M3Z B;  5DQV A;  1KEY A;  3N5L A;  2YK0 A;  4JYA T;  5LCY A;  2QVA A;  2CBI A;  3HI2 A;  3UUL A;  2LLY A;  1D0X A;  3AA1 B;  4AKI A;  2ZM0 A;  3MJX A;  3H3A A;  4AKR B;  4ANJ A;  4K0K T;  5FKY A;  3ZT5 A;  3ABV A;  3WAK A;  2A9U A;  5JDF A;  3FZM B;  3KBU A;  2HH7 A;  3RYF E;  3C98 B;  3NRX A;  1J5E T;  2E8I A;  3UQ4 A;  4O4L E;  2V8S V;  5JR9 B;  3FXD B;  5AFU L;  4H63 V;  1IJ5 A;  4KHZ F;  5IYZ E;  4DR3 T;  5JVD E;  1XWM A;  4P1N A;  1G8X A;  1N34 T;  4J2C A;  4QXC B;  5FXZ A;  2X0H A;  5GON E;  4PK6 A;  4PJN A;  3C4X A;  2EHO A;  5FY7 A;  3OVU A;  3N9M A;  3E0Z A;  2WB5 A;  5KXJ A;  3FZF B;  5BR8 T;  4X1K E;  4HFV A;  3PU8 A;  3PUQ A;  2RPA A;  2BS2 A;  3MKD A;  4EED A;  4UIG A;  4IL9 A;  4ZS2 A;  2CA5 A;  2E5L T;  3AE4 A;  4HGA A;  4JI0 T;  3RGL A;  3I9Y A;  4A5X A;  4TN7 B;  2ZM2 A;  5AQF B;  2XM2 A;  3K3O A;  2JQQ A;  4ZI2 D;  1KK7 A;  2CPT A;  1JNZ A;  2CLY C;  2YEV C;  3MAC A;  4CXX A;  1SA0 E;  3VRB A;  1HX1 B;  3DJB A;  2BVM A;  2XTL A;  2LRK A;  5AQO B;  4HFI A;  3NKZ A;  2CRB A;  1H7C A;  4IDQ A;  2WDQ A;  2XHE B;  5LGN B;  3LK4 2;  4ZEY A;  2H88 A;  4O4J E;  3ZMU B;  1MIW A;  2IW5 B;  4WZX A;  3OTO T;  5LYJ E;  5HCM A;  4I50 E;  4ZHQ E;  1KFY A;  1WYC A;  3ZST A;  4C90 A;  1OED E;  3VKH A;  2WSS V;  4LFB T;  1W9R A;  4H9R C;  3FZH B;  3VU7 H;  2KT9 A;  2FJD A;  4ILC A;  2ZM6 T;  1HS7 A;  5FNV E;  4Z8X A;  4QKN A;  4CI2 B;  3CX7 B;  4WYV A;  3BK9 A;  4UF0 A;  4DMW A;  4HFE A;  2MBG A;  4AIS A;  4HFD A;  4K0U A;  3EVY A;  3P4W A;  2NW8 A;  3AE1 A;  3PUV F;  5DQW A;  4UVA B;  3SOL A;  2WDR A;  4IE7 A;  4TNW A;  3AA0 B;  4DV2 T;  4LF5 T;  3U78 A;  4LFA T;  3CKD A;  3LSV A;  4WBN E;  4ZI7 E;  4DID B;  2ES0 A;  3ZMV B;  2N9D A;  2X68 A;  5LHH B;  1OED C;  3KV9 A;  3ZN1 B;  3RYC E;  4DR6 T;  1VCT A;  2DI4 A;  2PTF A;  4JLE A;  2QRX A;  4IE5 A;  5ABF A;  4I55 E;  4UXN B;  5FMN A;  3RX6 A;  5IWA T;  4DV3 T;  1CHU A;  4ZI2 C;  4OK0 A;  2VKO A;  3AA6 B;  3JAF A;  2BBJ A;  3O9X A;  4TWD A;  4A98 A;  3UUB A;  3LDQ B;  1YD8 G;  2QYW A;  2X67 A;  5J2U E;  4TV9 E;  1MIY A;  2J4G A;  1BR1 A;  5CA0 E;  5JDL A;  5BMV E;  5EK4 A;  4L9I A;  4DR4 T;  2XQ6 A;  3CQX C;  3L39 A;  2V7J A;  2XQ9 A;  1E7P A;  3T1H T;  5FVL A;  4GK0 E;  2K24 A;  5IHY A;  3IHR A;  3AE8 A;  4EAH A;  2XAF B;  1HR0 T;  4ZZB A;  5AQI B;  2YDS A;  5AQG B;  1UX5 A;  4CXW A;  3OBV E;  4EV6 A;  1T98 A;  3UUN A;  3K3N A;  2CLY B;  5LXT E;  4FJO A;  2W2U A;  2E2A A;  2UXC T;  4ZI3 D;  4DMV A;  1SHZ C;  4ERR A;  4HWC A;  3O1H A;  1X79 A;  3KV5 A;  4HTE A;  4Z90 A;  1T72 A;  2VKH A;  2CBJ A;  5AQR B; 
#chains in the Genus database with same CATH homology
 5AQG B;  1UGO A;  3FZL B;  3LDQ B;  3FZH B;  5AQM B;  3FZK B;  1HX1 B;  3A8Y C;  1I6Z A;  5AQQ B;  1T7S A;  4HWD A;  4HWH A;  5AQO B;  5AQV B;  5AQN B;  3M3Z B;  5AQF B;  5AQL B;  5AQU B;  4HWI B;  5AQT B;  4HWC A;  5AQH B;  2D9D A;  4HWF A;  5AQJ B;  5AQK B;  1M62 A;  5AQI B;  5AQS B;  3FZF B;  3FZM B;  1M7K A;  1UK5 A;  5AQR B;  5AQP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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