3L8IA

Crystal structure of ccm3, a cerebral cavernous malformation protein critical for vascular integrity
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
198
structure length
198
Chain Sequence
TSMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFVSANRLIHQTNLILQTFKTVA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Programmed cell death protein 10
total genus 74
structure length 198
sequence length 198
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2009-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06840 DUF1241 Protein of unknown function (DUF1241)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 3l8iA01
1.20.120.330 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Nucleotidyltransferases domain 2 3l8iA02
3MFNA 5F28E 1KTMA 3L8JA 3TULA 1OW7A 1O3UA 3K7DA 1QVXA 1JOGA 4XEKA 4NQFA 1WWPA 3W8IB 2L6HA 2LK4A 3RQFA 3BRJA 1K04A 3GM2A 3JYYA 4XEFA 1UFBA 3GM1A 3O10A 3JZ0A 2JPUA 3C8GD 1WOLA 3B71A 4EBKA 3L8IA 3AJMA 2L6FA 2L6GA 4R32A 4XEVA 4GEHB 3C18A 4EBJA 2KK1A 2YWAA 3C8GB 3U3FA 1OW8A 2Q00A 3S9OA 1K40A 1PV3A 3W8HB 3RQGA 1V4AA 1KNYA 1WTYA 2PBEA 1OW6A 2JX0A 3U0CA 3C8GA 2HSBA 1K05A 3GM3A 3RQEA 1ZZPA
chains in the Genus database with same CATH superfamily
3OEOA 4DBRA 2CYDA 3S29A 5A69A 2CNWD 1MQVA 4IRUA 3ABKC 3EG9A 4DOZA 1OQCA 2P6VA 1AVOB 4I3MA 1Z3IX 2WZFA 3DE9A 2ZQQA 2X51A 5JS5A 5EHHA 4MW3A 4U9DA 3AG2C 4IAQA 5L3VA 3NYLA 2EPOA 4QI2A 2YLIA 2WB7A 4F47A 2M4EA 3AM1A 5T3WA 2NG1A 2YWAA 1Z63A 1VTMP 2TMVP 3T88A 3RQEA 2V3CC 2FFHA 3TD7A 4K2NA 3NYJA 4BJTA 4BEMJ 4P9FA 3PZKA 2ZXPA 4OINF 3GEHA 3S0XA 2PPYA 4YN0B 3OC7A 5AGFA 3EGDA 1Z5ZA 3PHF2 1VOMA 2EILC 2R7OA 1RKEA 3ZVRA 3FAPB 2J9UA 2WZLA 4IGGA 3UMIA 4EKWA 2QY9A 3DAFA 4Q4ZF 2XLMA 3C8GD 2D4UA 4CBEA 2NSFA 2IOQA 4MW8A 3EZHA 4U5BE 2I8BA 1LS1A 3T9OA 4IARA 1PD1A 4OIPF 4MTGA 3FOOA 3ZTZA 1L7CA 2R25A 1LKXA 4NY3A 3DMDA 2WVNA 3ZG1A 3UR3C 3HNIA 4OIOF 2LCHA 2P0NA 1H9GA 1DOVA 4BJ1A 1TR2A 4WJ0A 4I4ZA 3TULA 1UX4A 2MWQA 1T9KA 4WGYA 5FCLA 4JYLA 4JFCA 5F5FA 4HE8D 2GTRA 1FFTC 3U9JA 4LLEA 1E86A 1L3PA 4JW1A 4N6CA 3L8JA 4U5GA 2W45A 4G7OF 4MVQA 2L6FA 5EK0A 4CJOA 3PDMP 1OXKA 4JEBA 4U5CE 1CGOA 3LUTB 4GYTA 3DM5A 3T6GB 2HV6A 1ZHWA 4A2NB 5DQZA 1G8XA 2I15A 3C8ZA 1H7IA 3RYLA 4P6IC 2A6EF 3C8GB 1HE1A 3FVYA 1A7VA 3EPVA 3V5XA 2XLDA 3K1IC 2RSEB 3SXZA 1YAUO 3LNMB 5E2QA 3AQBA 1A7EA 3RQFA 5EGYA 3ZIBA 3VF0A 4H54A 1PV3A 4YL1A 5KYXA 2Q7RA 1OXBA 4ONSA 4QI0A 4XLPF 4W8KA 3SEOA 1O3UA 2YEVA 1UG7A 3N0TA 4G78A 1VLTA 5COGA 4JCSA 3ITFA 1M2OA 2MYSA 2YLDA 4I42A 2XXAB 4JIOA 2R7UA 2J0WA 4Q5SF 4PJNA 1O5HA 2W4BA 2IYLD 4BJ6C 5F5HA 2ETSA 4X0RA 4ZLCA 4C3DA 2GWWA 3U0CA 3V5YA 2CGEA 3JTLO 1D1AA 1J8MF 3MOYA 4E0HA 4AL1A 2JPUA 4OLQA 2QE9A 3Q7LA 1XZQA 4MS2A 4ANJA 4JEAA 2L9JA 2QTVA 4U1AA 1EF9A 1T5OA 2UZFA 1NFNA 2L81A 4CDVA 2KYHA 3SWXA 4JTAB 1OKKA 5B3IA 2EPMX 1YARO 1Y6DA 3ZTMA 1I4YA 1WOLA 5L0CA 3NMKA 2A6HF 4K7BA 3I5QA 3MYIA 1Q0DA 3SP1A 2J7PA 1JXZA 2ASRA 4DJ9A 2QUPA 3QTHA 5JLIA 4XPYA 4JRZA 3EFOA 3ADBA 1TWCA 1WGWA 5C9GA 2A0UA 2J9VA 4H4KC 1LI7A 1T6QA 1QPUA 3MBGA 1WTYA 5AC5A 1QQ3A 2P63A 4QIIA 2Y3DA 3B0VC 2OU6A 2X0CA 2ZQRA 4EUKB 1UFBA 3UGOA 2PF4E 2DYRC 1BR4A 3G50A 4N6HA 1CPQA 5KYYA 2HS5A 3I5PA 2ICWG 3GWLA 1SF8A 3KQFA 4PJMA 1T01A 2VX2A 4CIPA 1Q0MA 2AWYA 1ZU5A 3RQGA 3O4XE 3N24A 1EQ1A 2NUTB 2OEXA 3TQOA 3G4XA 4BEJA 2YKZA 1M2VB 4NC3A 4CJGA 4N4WA 1IZMA 3QMKA 2LSEA 4E18A 3W8HB 1V4AA 3IEEA 1FFHA 1R4TA 1KNYA 2ZPAA 4FAPB 1J8YF 1ORJA 2IM8A 5BQIA 2ZD9A 3FHDA 4DRHB 1C17M 1O87A 2PX3A 3FOPA 2YL3A 3X1OA 2NUPA 3ZDLA 3P5MA 2HW5A 3ADDA 3EH2A 4I1MA 2XM4A 1UX5A 4XQ1A 4PJLA 3JRMO 4YT5A 3U3FA 3FXHA 3H02A 4O6MA 2YLGA 2YRFA 4FZWC 5BQGA 2Y3GA 4RD9A 3K33A 2IEXA 1Y64B 4YT2A 3LS0A 4J7TA 4BJ5A 1Q52A 1OW8A 5KYUA 2IBFA 1G4WR 2YQYA 4G7HF 3UNGC 1SR2A 1E2XA 2VH3A 3KYIA 3WODF 2EIMC 3T4RA 4NCQA 4JVSA 5IY5C 5COMA 4AK9A 5B1AC 3NG1A 1NU7D 3ASNC 3MLGA 1GGQA 3MX3A 5DLJA 2B0HA 4AE4A 2KC3A 3W8IB 1E83A 1K04A 2C04A 3C18A 1NZYB 3U5SA 3A4LA 1M57C 3GEIA 4JCHA 4N06A 1RJ9A 1ZW2A 1XWJA 4MVMA 5GPGB 5JVEA 2XS8A 4GEHB 1ZHTA 3AOUA 3M4BA 3RW0A 3IQCA 5A6BD 3R0OA 3AG1C 2VREA 3J06A 2GDCA 3ABMC 1QVXA 4WCZA 4XEFA 3ZC4A 3TOMA 2Q9AA 1VB5A 3DAGA 4O6YA 1HW1A 5D92A 4PACA 4FWVA 1NG1A 2XM0A 2R05A 1V54C 3S28A 3AQCA 4OIQF 4NEKA 2LIGA 4LDRA 1U89A 2ZXOA 4MTOA 3QW0A 3HLZA 4OG1A 1WN0A 4BJ5C 1BZ4A 3DKAA 3ZQVA 2HJMA 5D91A 2GAQA 4EBKA 3R2PA 3LEOA 3SZRA 4OD4A 3US6A 2R7XA 3U8VA 5CIVA 5HV9A 3HNLA 1BR1A 1WZ8A 4GQHA 3GM2A 1QLEC 3CAXA 4U9EA 1EKYA 1NSGB 3I47A 2D5RB 2L7AA 1YLMA 4C3BA 5A6KA 2YL1A 3K7DA 3N2ZB 2L6HA 3IQ5A 3SLLA 3NMIA 3MYBA 2YZSA 1ZHZA 4MVOA 1B68A 3SXKA 5A6JA 5E33A 5CI8A 1D0XA 2OCCC 3W2VA 4YWQA 4LERA 4K0DA 5DS5A 3RVYA 4KI2A 2DUBA 3OA1A 1VMAA 3HKKA 1G5ZA 4EIYA 3E9VA 3K66A 3GWNA 1Z7Qc 2CNWA 2LFDA 5L0GA 1I4ZA 2YL0A 1ZVZA 2XRHA 2BE5F 4KC9A 1RCPA 4CS9A 4UDVA 1NFOA 3ZQYA 5E3AA 5KYWB 1Y4CA 3EHNA 4JTDB 3R7CA 4KBLA 2IXPA 1T6IA 2XSEA 3DWWA 2J0XA 3FDQA 4OIRF 5JT4A 1MJ3A 5JP7A 2NPUA 4U19A 4IWBA 3QVYA 5KJPA 2A68F 2PNOA 3RIPA 5JBXA 2OJED 4K1OA 2VC9A 1WWPA 3H2UA 4JTCB 3B71A 2G3VA 3POVA 3O39A 3X2QC 3JYHA 3QW1A 4CS8A 2HMZA 3Q6MA 1GS9A 2HMQA 1QSPA 1EI7A 4I52A 2Y39A 4K3WA 3DM9B 3Q0JA 2BC5A 4HFKB 2WVOA 2YHSA 1NU9C 2VB6A 3DZAA 1I5NA 2H7BA 1VLSA 2DGJA 2R02A 3RSIA 4WABA 3C8GA 3DXJF 2G3KA 2P61A 3EFOB 3HNKA 1ZZPA 5F28E 2QNLA 4CDAA 1YJGA 4Q7CA 5CI9A 2XL8A 1MNDA 3EHMA 3Q6NA 4C7OA 1K40A 3DD7A 4U5EE 3ABLC 3LAYA 2A0BA 2LD6A 1YYXA 1KTMA 4JJFA 3CZ6A 5DS4A 1Q0KA 1TWHA 3JZ0A 3KH2A 3C62A 4ULWA 2QLAA 2EIKC 2O9XA 4U5DE 4CS9C 2HFIA 2JX0A 1BR2A 2XXAA 2A69F 1YVIA 5BUOA 3ATPA 3M15A 3IQTA 4KNPA 3QXZA 4ZLDA 3V5ZA 5T1DB 4ER9A 3RVZA 2F22A 3TJ6A 3A4NA 3T89A 3C63A 4ELWA 5KYNA 4U18A 3R9SA 3GM1A 4MI2A 3LJBA 4PFOA 2J45A 3TJ5A 3B9QA 3NMJA 3R9TA 2G62A 1MMNA 3DJUB 3ADCA 4YT4A 1OCOC 3VYWA 3KYJA 3JSEO 3EQLF 4YK5A 5AC4A 1QKRA 2A1DD 4IZDA 1JPNA 3JT1A 1A0BA 1HMOA 4LACB 2KGOA 4C3EA 3NKEA 4Z9IA 2EINC 5E3CA 5KYUB 5L0FA 1OCZC 2KK1A 2LFFA 1C02A 2HUJA 4ELSA 4W8PA 1NBBA 3GM3A 4J30B 3EGXA 2VCAA 3S84A 1E84A 3U8PA 5B1BC 4JWVA 3Q1TA 4OD5A 4AE4B 3TRRA 3NKDA 2OG2A 2H7VC 2HSBA 4EWCA 3EG9B 4JJGA 4PR9A 2YL7A 3C7JA 4MTFA 1YZCA 3JCUQ 2XS1A 5JSLA 3IQ6A 4Z9HA 3NDBB 2LQGA 2PBEA 2AWCA 2EJ5A 3A11A 2ZXWC 3UGPA 2XL6A 1JAFA 4DXWA 2NUTA 4JZAA 3QXIA 4ELXA 3VM6A 1JRAA 3U3BA 3L8IA 3U2LA 4G0HA 2J46A 4FESA 4ULVA 1RMVA 4MVSA 3GANA 5L0HA 1E85A 1ORYA 3FMSA 4M63A 4JE9A 4EBBA 1IW7F 4MVUA 3GORA 1V55C 3ASOC 4HFFB 1K05A 3W8HA 4FX5A 1LIHA 3W2WA 3H65A 2V26A 1APCA 3AJMA 2L6GA 2HZ8A 2FBMA 2HJ3A 1EF8A 2M64A 1FR0A 4YL0A 1OW6A 3EGDB 1JPJA 4JOTA 1LI5A 3LS1A 3Q0GA 1JOGA 2W9YA 2KW3C 3O6XA 1RKEB 2R7SA 4LDKA 1LM3B 3HTKC 5JRAA 3JRTA 2R9RB 2PX0A 4P9TA 2DYSC 1HMDA 1JMWA 1ZHXA 1TFKB 1LVKA 2KJGA 3JYYA 1ZYRF 2MHRA 4RBNA 4MVRA 2HSQA 2IXOA 4PJJA 1AUEA 4D4XA 4IB4A 3F46A 1TWGA 2Y69C 3CSKA 1AEPA 2KQ9A 1GQAA 3IRBA 1ZHYA 2OOCA 3ZSUA 3T8AA 2DI3A 2Q9CA 2HV7A 3W8IA 4J7YA 5JBWA 3LNRA 2F6QA 1FTSA 2OJQA 1HZDA 3QZCA 4XWJA 1NZYA 4XLNF 2J9WA 2E87A 4YT8A 2UUHA 1DOWA 4NTBA 2P1AA 5L0IA 3K1IA 3Q7GA 2IXMA 4JURI 1RKCA 1QZXA 1XZPA 1TWAA 4XPXA 2R03A 4IAOA 4EHPA 1RJNA 2GFHA 4BPMA 4GEHA 4PFPA 3UMHA 3TK0A 1OCCC 1TFOB 3FAJA 2DB4A 3AGUA 4IJJA 4RDAA 1ZU4A 3LESA 4DRJB 1JR8A 3WAQA 3BEHA 2XLHA 3EZIA 2XL4A 2CCYA 3RFYA 1ORSC 3S90A 4XEVA 2EPNA 2VASA 2R7TA 1RXQA 2W4MA 2NSGA 3OWTA 4LDQA 1OKKD 2Q4FA 5JUAA 4NTFA 2XLWA 2HKVA 2IXNA 5L0JA 4YL3A 3V7OA 1PCXA 4FJWD 3IHUA 3AGTA 4BJ6A 2R7QA 3CEXA 3K1HA 1UIYA 4NTAA 3E70C 3BRJA 3G64A 3W4YA 1FNTc 1LE4A 2J7PD 3U2MA 2JD3A 1KU2A 3M4CA 5L0DA 3AG4C 5KYXB 5B3SC 2R7WA 3SXYA 2Q3TA 1BBHA 1HW2A 4U5FE 1T6UA 2KSFA 2Z15A 3EJNA 4MQ9F 2LK4A 4Z9JA 3T6JA 3TLFA 1VYIA 4IZCA 3HINA 1PD0A 4I44A 2XLVA 1H6GA 1LPEA 3G4ZA 3WHNA 4F4BA 5HSWA 2EPKX 5A6BA 2AU5A 2FGYA 1CGME 1WASA 3SXMA 4CS7A 3S9OA 1FAPB 1TQGA 2H7OA 4E17A 3M79A 2J8WA 3TOLA 4C7OB 3A4MA 1NZEA 4L6RA 3AG3C 3UMKA 3GODA 2H8AA 4PK4A 3HRXA 1VYKA 4U5HA 2R7VA 1Q51A 3HNJA 1CGNA 1LE2A 2R7RA 3WG7C 2XLEA 3H2VA 1S05A 3DE8A 1RJMA 1Q0FA 3NRHA 3QK8A 1MMAA 3PMRA 4HEAJ 2Q00A 1F1MA 3L34A 4B6IA 4BG0A 2Q9BA 3DI5A 4DRIB 1HE9A 4O79A 5KYWA 4MNDA 4JKVA 4NQFA 1A41A 3IPMO 4D4NA 1YA9A 2RD9A 2EIJC 3LLKA 2PFDA 4CSAA 3KMIA 1VK5A 1OW7A 4NNQA 3ZWIA 3VRCA 1OR3A 4I1OB 5KYYB 4AX2A 2FW2A 3FDUA 3HJCA 4KNWA 3NYMA 3DJNB 4G7ZF 4IZBA 4DBQA 1R5ID 2LP4A 3F47A 1SYQA 2XLOA 1MMGA 1SMYF 4FZWA 1WATA 3M1CB 4CX9A 3SNHA 4DVZA 256BA 3GEEA 2PBPA 2Y3HA 2YVKA 2FAPB 1U6HA 3H81A 3L1MA 1A7DA 1D0YA 3O10A 3EH1A 2OEVA 5FZTA 3VAYA 1N1CA 3K6BA 1S7ZA 4XTKA 3EGXB 1M6TA 2NUPB 4CS8C 2UUIA 3MFNA 3RKOF 3RH3A 4MOUA 1C03A 4E7ZA 1M56C 4AL0A 1GM5A 1ZW3A 4E7SA 4ZU2A 4MVZA 5DS6A 1OR2A 1U0BB 2AP3A 1D1CA 1D1BA 2J9BA 3MYFA 4CIHA 2GA0A 3PCVA 1YYJA 4XEKA 1DCIA 1ST6A 2EPLX 2WVQA 3SYNA 3KL4A 3I4UA 2Y3BA 4EMLA 5BQHA 2OKUA 2VCBA 3L0IA 3LLIA 1YZAA 1SZIA 3JSZA 3T6BA 3U9MA 2ZXRA 1Q0GA 1H9TA 1G4US 5L3QA 2VCCA 5TJ5E 3RF3A 4KNVA 5COFA 1MNEA 4CSAC 2AVKA 2PP4A 4JCZA 4JC7A 4LLCA 2BL2A 5DVWA 1OCRC 5T3TA 5K0IA 2CDQA 3B0UX 3KPHA 5A6AA 4A4AA 1V74B 3CQZA 4O6NA 1D0ZA 4R32A 4QIJA 1W2WA 1YA7O 1Z23A 1RJ9B 1FMWA 3QVZA 1NLXA 1Z6AA 3O55A 1DUBA 1FMVA 2C03A 2WL8A 4QDLA 4DVYP 2CW0F 4CDYA 1CPRA 1EA8A 3LEVA 3KKBA 1YDIA 4O7GA 4EBJA 2B0JA 1M2VA 4WGZA 3S27A 1EY3A 1LS4A 3B0PA 1MMDA 2OQMA 1TKNA 2KNHA 3B29A 3A9CA 4E0IA 4XPWA 4YJWA 5DQTA 2QQ3A 2P7VA 1HY5A 3ECSA 4J32B 1BDJB 2WZGA
chains in the Genus database with same CATH topology
3A4MA 3JYYA 3GM1A 2JPUA 3C8GD 3C8GB 3RQGA 3O4XE 3ADCA 2PBEA 3C8GA 1ZZPA 5F28E 3IRBA 3BRJA 3W8IB 3RQFA 1K04A 3O10A 1RJMA 1WOLA 4EBKA 3L8IA 4R32A 3AM1A 3C18A 2YWAA 2Q00A 1K40A 1PV3A 3W8HB 3A4LA 1V4AA 1KNYA 1K05A 3RQEA 3MFNA 1KTMA 3TULA 1UX4A 1O3UA 4NQFA 2LK4A 3GM2A 3ADBA 3ADDA 3JZ0A 3AJMA 2L6GA 4GEHB 4EBJA 1UX5A 2KK1A 3U3FA 1WTYA 1OW6A 2JX0A 3GM3A 2P63A 3L8JA 1OW7A 3K7DA 1QVXA 1JOGA 4XEKA 1WWPA 2L6HA 4XEFA 4NNQA 1Y64B 1UFBA 3B71A 2L6FA 1OW8A 3S9OA 3A4NA 3U0CA 2HSBA 4XEVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MFN A;  5F28 E;  1KTM A;  3L8J A;  3TUL A;  1OW7 A;  1O3U A;  3K7D A;  1QVX A;  1JOG A;  4XEK A;  4NQF A;  1WWP A;  3W8I B;  2L6H A;  2LK4 A;  3RQF A;  3BRJ A;  1K04 A;  3GM2 A;  3JYY A;  4XEF A;  1UFB A;  3GM1 A;  3O10 A;  3JZ0 A;  2JPU A;  3C8G D;  1WOL A;  3B71 A;  4EBK A;  3L8I A;  3AJM A;  2L6F A;  2L6G A;  4R32 A;  4XEV A;  4GEH B;  3C18 A;  4EBJ A;  2KK1 A;  2YWA A;  3C8G B;  3U3F A;  1OW8 A;  2Q00 A;  3S9O A;  1K40 A;  1PV3 A;  3W8H B;  3RQG A;  1V4A A;  1KNY A;  1WTY A;  2PBE A;  1OW6 A;  2JX0 A;  3U0C A;  3C8G A;  2HSB A;  1K05 A;  3GM3 A;  3RQE A;  1ZZP A; 
#chains in the Genus database with same CATH topology
 3OEO A;  4DBR A;  2CYD A;  3S29 A;  5A69 A;  2CNW D;  1MQV A;  4IRU A;  3ABK C;  3EG9 A;  4DOZ A;  1OQC A;  2P6V A;  1AVO B;  4I3M A;  1Z3I X;  2WZF A;  3DE9 A;  2ZQQ A;  2X51 A;  5JS5 A;  5EHH A;  4MW3 A;  4U9D A;  3AG2 C;  4IAQ A;  5L3V A;  3NYL A;  2EPO A;  4QI2 A;  2YLI A;  2WB7 A;  4F47 A;  2M4E A;  3AM1 A;  5T3W A;  2NG1 A;  2YWA A;  1Z63 A;  1VTM P;  2TMV P;  3T88 A;  3RQE A;  2V3C C;  2FFH A;  3TD7 A;  4K2N A;  3NYJ A;  4BJT A;  4BEM J;  4P9F A;  3PZK A;  2ZXP A;  4OIN F;  3GEH A;  3S0X A;  2PPY A;  4YN0 B;  3OC7 A;  5AGF A;  3EGD A;  1Z5Z A;  3PHF 2;  1VOM A;  2EIL C;  2R7O A;  1RKE A;  3ZVR A;  3FAP B;  2J9U A;  2WZL A;  4IGG A;  3UMI A;  4EKW A;  2QY9 A;  3DAF A;  4Q4Z F;  2XLM A;  3C8G D;  2D4U A;  4CBE A;  2NSF A;  2IOQ A;  4MW8 A;  3EZH A;  4U5B E;  2I8B A;  1LS1 A;  3T9O A;  4IAR A;  1PD1 A;  4OIP F;  4MTG A;  3FOO A;  3ZTZ A;  1L7C A;  2R25 A;  1LKX A;  4NY3 A;  3DMD A;  2WVN A;  3ZG1 A;  3UR3 C;  3HNI A;  4OIO F;  2LCH A;  2P0N A;  1H9G A;  1DOV A;  4BJ1 A;  1TR2 A;  4WJ0 A;  4I4Z A;  3TUL A;  1UX4 A;  2MWQ A;  1T9K A;  4WGY A;  5FCL A;  4JYL A;  4JFC A;  5F5F A;  4HE8 D;  2GTR A;  1FFT C;  3U9J A;  4LLE A;  1E86 A;  1L3P A;  4JW1 A;  4N6C A;  3L8J A;  4U5G A;  2W45 A;  4G7O F;  4MVQ A;  2L6F A;  5EK0 A;  4CJO A;  3PDM P;  1OXK A;  4JEB A;  4U5C E;  1CGO A;  3LUT B;  4GYT A;  3DM5 A;  3T6G B;  2HV6 A;  1ZHW A;  4A2N B;  5DQZ A;  1G8X A;  2I15 A;  3C8Z A;  1H7I A;  3RYL A;  4P6I C;  2A6E F;  3C8G B;  1HE1 A;  3FVY A;  1A7V A;  3EPV A;  3V5X A;  2XLD A;  3K1I C;  2RSE B;  3SXZ A;  1YAU O;  3LNM B;  5E2Q A;  3AQB A;  1A7E A;  3RQF A;  5EGY A;  3ZIB A;  3VF0 A;  4H54 A;  1PV3 A;  4YL1 A;  5KYX A;  2Q7R A;  1OXB A;  4ONS A;  4QI0 A;  4XLP F;  4W8K A;  3SEO A;  1O3U A;  2YEV A;  1UG7 A;  3N0T A;  4G78 A;  1VLT A;  5COG A;  4JCS A;  3ITF A;  1M2O A;  2MYS A;  2YLD A;  4I42 A;  2XXA B;  4JIO A;  2R7U A;  2J0W A;  4Q5S F;  4PJN A;  1O5H A;  2W4B A;  2IYL D;  4BJ6 C;  5F5H A;  2ETS A;  4X0R A;  4ZLC A;  4C3D A;  2GWW A;  3U0C A;  3V5Y A;  2CGE A;  3JTL O;  1D1A A;  1J8M F;  3MOY A;  4E0H A;  4AL1 A;  2JPU A;  4OLQ A;  2QE9 A;  3Q7L A;  1XZQ A;  4MS2 A;  4ANJ A;  4JEA A;  2L9J A;  2QTV A;  4U1A A;  1EF9 A;  1T5O A;  2UZF A;  1NFN A;  2L81 A;  4CDV A;  2KYH A;  3SWX A;  4JTA B;  1OKK A;  5B3I A;  2EPM X;  1YAR O;  1Y6D A;  3ZTM A;  1I4Y A;  1WOL A;  5L0C A;  3NMK A;  2A6H F;  4K7B A;  3I5Q A;  3MYI A;  1Q0D A;  3SP1 A;  2J7P A;  1JXZ A;  2ASR A;  4DJ9 A;  2QUP A;  3QTH A;  5JLI A;  4XPY A;  4JRZ A;  3EFO A;  3ADB A;  1TWC A;  1WGW A;  5C9G A;  2A0U A;  2J9V A;  4H4K C;  1LI7 A;  1T6Q A;  1QPU A;  3MBG A;  1WTY A;  5AC5 A;  1QQ3 A;  2P63 A;  4QII A;  2Y3D A;  3B0V C;  2OU6 A;  2X0C A;  2ZQR A;  4EUK B;  1UFB A;  3UGO A;  2PF4 E;  2DYR C;  1BR4 A;  3G50 A;  4N6H A;  1CPQ A;  5KYY A;  2HS5 A;  3I5P A;  2ICW G;  3GWL A;  1SF8 A;  3KQF A;  4PJM A;  1T01 A;  2VX2 A;  4CIP A;  1Q0M A;  2AWY A;  1ZU5 A;  3RQG A;  3O4X E;  3N24 A;  1EQ1 A;  2NUT B;  2OEX A;  3TQO A;  3G4X A;  4BEJ A;  2YKZ A;  1M2V B;  4NC3 A;  4CJG A;  4N4W A;  1IZM A;  3QMK A;  2LSE A;  4E18 A;  3W8H B;  1V4A A;  3IEE A;  1FFH A;  1R4T A;  1KNY A;  2ZPA A;  4FAP B;  1J8Y F;  1ORJ A;  2IM8 A;  5BQI A;  2ZD9 A;  3FHD A;  4DRH B;  1C17 M;  1O87 A;  2PX3 A;  3FOP A;  2YL3 A;  3X1O A;  2NUP A;  3ZDL A;  3P5M A;  2HW5 A;  3ADD A;  3EH2 A;  4I1M A;  2XM4 A;  1UX5 A;  4XQ1 A;  4PJL A;  3JRM O;  4YT5 A;  3U3F A;  3FXH A;  3H02 A;  4O6M A;  2YLG A;  2YRF A;  4FZW C;  5BQG A;  2Y3G A;  4RD9 A;  3K33 A;  2IEX A;  1Y64 B;  4YT2 A;  3LS0 A;  4J7T A;  4BJ5 A;  1Q52 A;  1OW8 A;  5KYU A;  2IBF A;  1G4W R;  2YQY A;  4G7H F;  3UNG C;  1SR2 A;  1E2X A;  2VH3 A;  3KYI A;  3WOD F;  2EIM C;  3T4R A;  4NCQ A;  4JVS A;  5IY5 C;  5COM A;  4AK9 A;  5B1A C;  3NG1 A;  1NU7 D;  3ASN C;  3MLG A;  1GGQ A;  3MX3 A;  5DLJ A;  2B0H A;  4AE4 A;  2KC3 A;  3W8I B;  1E83 A;  1K04 A;  2C04 A;  3C18 A;  1NZY B;  3U5S A;  3A4L A;  1M57 C;  3GEI A;  4JCH A;  4N06 A;  1RJ9 A;  1ZW2 A;  1XWJ A;  4MVM A;  5GPG B;  5JVE A;  2XS8 A;  4GEH B;  1ZHT A;  3AOU A;  3M4B A;  3RW0 A;  3IQC A;  5A6B D;  3R0O A;  3AG1 C;  2VRE A;  3J06 A;  2GDC A;  3ABM C;  1QVX A;  4WCZ A;  4XEF A;  3ZC4 A;  3TOM A;  2Q9A A;  1VB5 A;  3DAG A;  4O6Y A;  1HW1 A;  5D92 A;  4PAC A;  4FWV A;  1NG1 A;  2XM0 A;  2R05 A;  1V54 C;  3S28 A;  3AQC A;  4OIQ F;  4NEK A;  2LIG A;  4LDR A;  1U89 A;  2ZXO A;  4MTO A;  3QW0 A;  3HLZ A;  4OG1 A;  1WN0 A;  4BJ5 C;  1BZ4 A;  3DKA A;  3ZQV A;  2HJM A;  5D91 A;  2GAQ A;  4EBK A;  3R2P A;  3LEO A;  3SZR A;  4OD4 A;  3US6 A;  2R7X A;  3U8V A;  5CIV A;  5HV9 A;  3HNL A;  1BR1 A;  1WZ8 A;  4GQH A;  3GM2 A;  1QLE C;  3CAX A;  4U9E A;  1EKY A;  1NSG B;  3I47 A;  2D5R B;  2L7A A;  1YLM A;  4C3B A;  5A6K A;  2YL1 A;  3K7D A;  3N2Z B;  2L6H A;  3IQ5 A;  3SLL A;  3NMI A;  3MYB A;  2YZS A;  1ZHZ A;  4MVO A;  1B68 A;  3SXK A;  5A6J A;  5E33 A;  5CI8 A;  1D0X A;  2OCC C;  3W2V A;  4YWQ A;  4LER A;  4K0D A;  5DS5 A;  3RVY A;  4KI2 A;  2DUB A;  3OA1 A;  1VMA A;  3HKK A;  1G5Z A;  4EIY A;  3E9V A;  3K66 A;  3GWN A;  1Z7Q c;  2CNW A;  2LFD A;  5L0G A;  1I4Z A;  2YL0 A;  1ZVZ A;  2XRH A;  2BE5 F;  4KC9 A;  1RCP A;  4CS9 A;  4UDV A;  1NFO A;  3ZQY A;  5E3A A;  5KYW B;  1Y4C A;  3EHN A;  4JTD B;  3R7C A;  4KBL A;  2IXP A;  1T6I A;  2XSE A;  3DWW A;  2J0X A;  3FDQ A;  4OIR F;  5JT4 A;  1MJ3 A;  5JP7 A;  2NPU A;  4U19 A;  4IWB A;  3QVY A;  5KJP A;  2A68 F;  2PNO A;  3RIP A;  5JBX A;  2OJE D;  4K1O A;  2VC9 A;  1WWP A;  3H2U A;  4JTC B;  3B71 A;  2G3V A;  3POV A;  3O39 A;  3X2Q C;  3JYH A;  3QW1 A;  4CS8 A;  2HMZ A;  3Q6M A;  1GS9 A;  2HMQ A;  1QSP A;  1EI7 A;  4I52 A;  2Y39 A;  4K3W A;  3DM9 B;  3Q0J A;  2BC5 A;  4HFK B;  2WVO A;  2YHS A;  1NU9 C;  2VB6 A;  3DZA A;  1I5N A;  2H7B A;  1VLS A;  2DGJ A;  2R02 A;  3RSI A;  4WAB A;  3C8G A;  3DXJ F;  2G3K A;  2P61 A;  3EFO B;  3HNK A;  1ZZP A;  5F28 E;  2QNL A;  4CDA A;  1YJG A;  4Q7C A;  5CI9 A;  2XL8 A;  1MND A;  3EHM A;  3Q6N A;  4C7O A;  1K40 A;  3DD7 A;  4U5E E;  3ABL C;  3LAY A;  2A0B A;  2LD6 A;  1YYX A;  1KTM A;  4JJF A;  3CZ6 A;  5DS4 A;  1Q0K A;  1TWH A;  3JZ0 A;  3KH2 A;  3C62 A;  4ULW A;  2QLA A;  2EIK C;  2O9X A;  4U5D E;  4CS9 C;  2HFI A;  2JX0 A;  1BR2 A;  2XXA A;  2A69 F;  1YVI A;  5BUO A;  3ATP A;  3M15 A;  3IQT A;  4KNP A;  3QXZ A;  4ZLD A;  3V5Z A;  5T1D B;  4ER9 A;  3RVZ A;  2F22 A;  3TJ6 A;  3A4N A;  3T89 A;  3C63 A;  4ELW A;  5KYN A;  4U18 A;  3R9S A;  3GM1 A;  4MI2 A;  3LJB A;  4PFO A;  2J45 A;  3TJ5 A;  3B9Q A;  3NMJ A;  3R9T A;  2G62 A;  1MMN A;  3DJU B;  3ADC A;  4YT4 A;  1OCO C;  3VYW A;  3KYJ A;  3JSE O;  3EQL F;  4YK5 A;  5AC4 A;  1QKR A;  2A1D D;  4IZD A;  1JPN A;  3JT1 A;  1A0B A;  1HMO A;  4LAC B;  2KGO A;  4C3E A;  3NKE A;  4Z9I A;  2EIN C;  5E3C A;  5KYU B;  5L0F A;  1OCZ C;  2KK1 A;  2LFF A;  1C02 A;  2HUJ A;  4ELS A;  4W8P A;  1NBB A;  3GM3 A;  4J30 B;  3EGX A;  2VCA A;  3S84 A;  1E84 A;  3U8P A;  5B1B C;  4JWV A;  3Q1T A;  4OD5 A;  4AE4 B;  3TRR A;  3NKD A;  2OG2 A;  2H7V C;  2HSB A;  4EWC A;  3EG9 B;  4JJG A;  4PR9 A;  2YL7 A;  3C7J A;  4MTF A;  1YZC A;  3JCU Q;  2XS1 A;  5JSL A;  3IQ6 A;  4Z9H A;  3NDB B;  2LQG A;  2PBE A;  2AWC A;  2EJ5 A;  3A11 A;  2ZXW C;  3UGP A;  2XL6 A;  1JAF A;  4DXW A;  2NUT A;  4JZA A;  3QXI A;  4ELX A;  3VM6 A;  1JRA A;  3U3B A;  3L8I A;  3U2L A;  4G0H A;  2J46 A;  4FES A;  4ULV A;  1RMV A;  4MVS A;  3GAN A;  5L0H A;  1E85 A;  1ORY A;  3FMS A;  4M63 A;  4JE9 A;  4EBB A;  1IW7 F;  4MVU A;  3GOR A;  1V55 C;  3ASO C;  4HFF B;  1K05 A;  3W8H A;  4FX5 A;  1LIH A;  3W2W A;  3H65 A;  2V26 A;  1APC A;  3AJM A;  2L6G A;  2HZ8 A;  2FBM A;  2HJ3 A;  1EF8 A;  2M64 A;  1FR0 A;  4YL0 A;  1OW6 A;  3EGD B;  1JPJ A;  4JOT A;  1LI5 A;  3LS1 A;  3Q0G A;  1JOG A;  2W9Y A;  2KW3 C;  3O6X A;  1RKE B;  2R7S A;  4LDK A;  1LM3 B;  3HTK C;  5JRA A;  3JRT A;  2R9R B;  2PX0 A;  4P9T A;  2DYS C;  1HMD A;  1JMW A;  1ZHX A;  1TFK B;  1LVK A;  2KJG A;  3JYY A;  1ZYR F;  2MHR A;  4RBN A;  4MVR A;  2HSQ A;  2IXO A;  4PJJ A;  1AUE A;  4D4X A;  4IB4 A;  3F46 A;  1TWG A;  2Y69 C;  3CSK A;  1AEP A;  2KQ9 A;  1GQA A;  3IRB A;  1ZHY A;  2OOC A;  3ZSU A;  3T8A A;  2DI3 A;  2Q9C A;  2HV7 A;  3W8I A;  4J7Y A;  5JBW A;  3LNR A;  2F6Q A;  1FTS A;  2OJQ A;  1HZD A;  3QZC A;  4XWJ A;  1NZY A;  4XLN F;  2J9W A;  2E87 A;  4YT8 A;  2UUH A;  1DOW A;  4NTB A;  2P1A A;  5L0I A;  3K1I A;  3Q7G A;  2IXM A;  4JUR I;  1RKC A;  1QZX A;  1XZP A;  1TWA A;  4XPX A;  2R03 A;  4IAO A;  4EHP A;  1RJN A;  2GFH A;  4BPM A;  4GEH A;  4PFP A;  3UMH A;  3TK0 A;  1OCC C;  1TFO B;  3FAJ A;  2DB4 A;  3AGU A;  4IJJ A;  4RDA A;  1ZU4 A;  3LES A;  4DRJ B;  1JR8 A;  3WAQ A;  3BEH A;  2XLH A;  3EZI A;  2XL4 A;  2CCY A;  3RFY A;  1ORS C;  3S90 A;  4XEV A;  2EPN A;  2VAS A;  2R7T A;  1RXQ A;  2W4M A;  2NSG A;  3OWT A;  4LDQ A;  1OKK D;  2Q4F A;  5JUA A;  4NTF A;  2XLW A;  2HKV A;  2IXN A;  5L0J A;  4YL3 A;  3V7O A;  1PCX A;  4FJW D;  3IHU A;  3AGT A;  4BJ6 A;  2R7Q A;  3CEX A;  3K1H A;  1UIY A;  4NTA A;  3E70 C;  3BRJ A;  3G64 A;  3W4Y A;  1FNT c;  1LE4 A;  2J7P D;  3U2M A;  2JD3 A;  1KU2 A;  3M4C A;  5L0D A;  3AG4 C;  5KYX B;  5B3S C;  2R7W A;  3SXY A;  2Q3T A;  1BBH A;  1HW2 A;  4U5F E;  1T6U A;  2KSF A;  2Z15 A;  3EJN A;  4MQ9 F;  2LK4 A;  4Z9J A;  3T6J A;  3TLF A;  1VYI A;  4IZC A;  3HIN A;  1PD0 A;  4I44 A;  2XLV A;  1H6G A;  1LPE A;  3G4Z A;  3WHN A;  4F4B A;  5HSW A;  2EPK X;  5A6B A;  2AU5 A;  2FGY A;  1CGM E;  1WAS A;  3SXM A;  4CS7 A;  3S9O A;  1FAP B;  1TQG A;  2H7O A;  4E17 A;  3M79 A;  2J8W A;  3TOL A;  4C7O B;  3A4M A;  1NZE A;  4L6R A;  3AG3 C;  3UMK A;  3GOD A;  2H8A A;  4PK4 A;  3HRX A;  1VYK A;  4U5H A;  2R7V A;  1Q51 A;  3HNJ A;  1CGN A;  1LE2 A;  2R7R A;  3WG7 C;  2XLE A;  3H2V A;  1S05 A;  3DE8 A;  1RJM A;  1Q0F A;  3NRH A;  3QK8 A;  1MMA A;  3PMR A;  4HEA J;  2Q00 A;  1F1M A;  3L34 A;  4B6I A;  4BG0 A;  2Q9B A;  3DI5 A;  4DRI B;  1HE9 A;  4O79 A;  5KYW A;  4MND A;  4JKV A;  4NQF A;  1A41 A;  3IPM O;  4D4N A;  1YA9 A;  2RD9 A;  2EIJ C;  3LLK A;  2PFD A;  4CSA A;  3KMI A;  1VK5 A;  1OW7 A;  4NNQ A;  3ZWI A;  3VRC A;  1OR3 A;  4I1O B;  5KYY B;  4AX2 A;  2FW2 A;  3FDU A;  3HJC A;  4KNW A;  3NYM A;  3DJN B;  4G7Z F;  4IZB A;  4DBQ A;  1R5I D;  2LP4 A;  3F47 A;  1SYQ A;  2XLO A;  1MMG A;  1SMY F;  4FZW A;  1WAT A;  3M1C B;  4CX9 A;  3SNH A;  4DVZ A;  256B A;  3GEE A;  2PBP A;  2Y3H A;  2YVK A;  2FAP B;  1U6H A;  3H81 A;  3L1M A;  1A7D A;  1D0Y A;  3O10 A;  3EH1 A;  2OEV A;  5FZT A;  3VAY A;  1N1C A;  3K6B A;  1S7Z A;  4XTK A;  3EGX B;  1M6T A;  2NUP B;  4CS8 C;  2UUI A;  3MFN A;  3RKO F;  3RH3 A;  4MOU A;  1C03 A;  4E7Z A;  1M56 C;  4AL0 A;  1GM5 A;  1ZW3 A;  4E7S A;  4ZU2 A;  4MVZ A;  5DS6 A;  1OR2 A;  1U0B B;  2AP3 A;  1D1C A;  1D1B A;  2J9B A;  3MYF A;  4CIH A;  2GA0 A;  3PCV A;  1YYJ A;  4XEK A;  1DCI A;  1ST6 A;  2EPL X;  2WVQ A;  3SYN A;  3KL4 A;  3I4U A;  2Y3B A;  4EML A;  5BQH A;  2OKU A;  2VCB A;  3L0I A;  3LLI A;  1YZA A;  1SZI A;  3JSZ A;  3T6B A;  3U9M A;  2ZXR A;  1Q0G A;  1H9T A;  1G4U S;  5L3Q A;  2VCC A;  5TJ5 E;  3RF3 A;  4KNV A;  5COF A;  1MNE A;  4CSA C;  2AVK A;  2PP4 A;  4JCZ A;  4JC7 A;  4LLC A;  2BL2 A;  5DVW A;  1OCR C;  5T3T A;  5K0I A;  2CDQ A;  3B0U X;  3KPH A;  5A6A A;  4A4A A;  1V74 B;  3CQZ A;  4O6N A;  1D0Z A;  4R32 A;  4QIJ A;  1W2W A;  1YA7 O;  1Z23 A;  1RJ9 B;  1FMW A;  3QVZ A;  1NLX A;  1Z6A A;  3O55 A;  1DUB A;  1FMV A;  2C03 A;  2WL8 A;  4QDL A;  4DVY P;  2CW0 F;  4CDY A;  1CPR A;  1EA8 A;  3LEV A;  3KKB A;  1YDI A;  4O7G A;  4EBJ A;  2B0J A;  1M2V A;  4WGZ A;  3S27 A;  1EY3 A;  1LS4 A;  3B0P A;  1MMD A;  2OQM A;  1TKN A;  2KNH A;  3B29 A;  3A9C A;  4E0I A;  4XPW A;  4YJW A;  5DQT A;  2QQ3 A;  2P7V A;  1HY5 A;  3ECS A;  4J32 B;  1BDJ B;  2WZG A; 
#chains in the Genus database with same CATH homology
 3A4M A;  3JYY A;  3GM1 A;  2JPU A;  3C8G D;  3C8G B;  3RQG A;  3O4X E;  3ADC A;  2PBE A;  3C8G A;  1ZZP A;  5F28 E;  3IRB A;  3BRJ A;  3W8I B;  3RQF A;  1K04 A;  3O10 A;  1RJM A;  1WOL A;  4EBK A;  3L8I A;  4R32 A;  3AM1 A;  3C18 A;  2YWA A;  2Q00 A;  1K40 A;  1PV3 A;  3W8H B;  3A4L A;  1V4A A;  1KNY A;  1K05 A;  3RQE A;  3MFN A;  1KTM A;  3TUL A;  1UX4 A;  1O3U A;  4NQF A;  2LK4 A;  3GM2 A;  3ADB A;  3ADD A;  3JZ0 A;  3AJM A;  2L6G A;  4GEH B;  4EBJ A;  1UX5 A;  2KK1 A;  3U3F A;  1WTY A;  1OW6 A;  2JX0 A;  3GM3 A;  2P63 A;  3L8J A;  1OW7 A;  3K7D A;  1QVX A;  1JOG A;  4XEK A;  1WWP A;  2L6H A;  4XEF A;  4NNQ A;  1Y64 B;  1UFB A;  3B71 A;  2L6F A;  1OW8 A;  3S9O A;  3A4N A;  3U0C A;  2HSB A;  4XEV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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