3L8IA

Crystal structure of ccm3, a cerebral cavernous malformation protein critical for vascular integrity
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
198
structure length
198
Chain Sequence
TSMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFVSANRLIHQTNLILQTFKTVA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Programmed cell death protein 10
total genus 74
structure length 198
sequence length 198
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2009-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06840 DUF1241 Protein of unknown function (DUF1241)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 3l8iA01
1.20.120.330 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Nucleotidyltransferases domain 2 3l8iA02
2Q00A 2HSBA 3B71A 3S9OA 1WOLA 1WWPA 2L6FA 3GM2A 3L8IA 2KK1A 5F28E 3TULA 3W8HB 4XEFA 1KTMA 2YWAA 3C18A 3RQGA 4R32A 3O10A 3L8JA 3JZ0A 1OW6A 3U0CA 4EBJA 1K40A 3BRJA 4XEKA 3GM1A 1PV3A 4EBKA 3W8IB 3U3FA 1KNYA 1V4AA 4NQFA 2L6GA 1K04A 3GM3A 4XEVA 2L6HA 3AJMA 2JX0A 2PBEA 3C8GD 1K05A 1UFBA 1QVXA 1ZZPA 2LK4A 3JYYA 1OW8A 3K7DA 3MFNA 3RQEA 1JOGA 1WTYA 3C8GA 3RQFA 2JPUA 4GEHB 3C8GB 1OW7A 1O3UA
chains in the Genus database with same CATH superfamily
1F1MA 2BL2A 3DM9B 3WG7C 2G62A 3C18A 2QTVA 4YK5A 3HINA 3NKEA 2HSQA 3SYNA 3TRRA 2EIKC 5HV9A 3OA1A 4G0HA 2LK4A 1TWHA 4D4NA 1C17M 1C02A 4J7TA 2F22A 3U2LA 3T89A 2KW3C 1JAFA 4MVRA 4DBQA 1E85A 2A6HF 1VK5A 4OD5A 3JSZA 2IEXA 4JURI 2XLDA 2P6VA 2G3KA 1G4WR 5AGFA 1ZU4A 3B0VC 2DGJA 1Q0GA 3H65A 5GPGB 2M4EA 2UUHA 1ORYA 2XLOA 3FOOA 2XM0A 1GQAA 2X0CA 5KYUA 4ULWA 1Z5ZA 5AC5A 1O87A 1TFOB 2L6HA 3FDUA 5JBWA 4YT4A 5KJPA 3MBGA 4J30B 4JOTA 2EINC 4NY3A 1YARO 1FAPB 4R32A 4K3WA 3U0CA 2Q9CA 2HMQA 2YL1A 3DI5A 1RKEA 3GWLA 4U5FE 4BEMJ 4FJWD 4N6HA 3V5XA 3R2PA 5A6BA 1LE2A 1U0BB 2MWQA 2H7OA 1K05A 1AVOB 5DQTA 1NFNA 3H81A 4O6YA 4MVMA 5COMA 3W2VA 1V55C 3IQ5A 2FAPB 2IXMA 2I15A 3EGXA 2VCAA 3U8PA 3B29A 5FZTA 5K0IA 4YT5A 3G4XA 4XWJA 4YT8A 4P9TA 4ONSA 5IY5C 2LSEA 2IXNA 4JRZA 3UR3C 5JS5A 2ZXPA 3I5PA 3W8IA 1D1BA 3P5MA 4G7HF 1H6GA 1KNYA 3A4NA 3AJMA 2WZFA 3K7DA 2P63A 3HNJA 4JZAA 3TJ5A 1AEPA 3IEEA 1NFOA 4FESA 3EGXB 3MYBA 3T6JA 4I52A 1OKKD 2IOQA 5E2QA 3GEIA 2IXPA 2VCCA 3K1IA 2M64A 1WTYA 1YJGA 4AE4B 3X2QC 1Z6AA 1RJNA 2EPMX 1Z3IX 2NUPA 4RBNA 5C9GA 4E7ZA 4EHPA 4XPXA 1YLMA 2AP3A 2H7BA 3SEOA 3MOYA 4EKWA 5BQGA 3DD7A 1K04A 2FGYA 1HY5A 2VASA 5KYWB 4XQ1A 3ZC4A 3L1MA 2WZGA 1SYQA 1GM5A 2VREA 3U2MA 3G64A 3S0XA 3T8AA 5DVWA 4YL1A 3KQFA 3T6BA 3U5SA 2NUTA 4BJTA 2Q9BA 2HW5A 3PZKA 3A9CA 4JEBA 4WGYA 2EPOA 4JCHA 4O6MA 1A0BA 3RVZA 2A1DD 3QMKA 1BDJB 2VC9A 1EY3A 4JWVA 1WASA 4K1OA 4YT2A 3B71A 3R0OA 3SXMA 2E87A 1ZU5A 1ZHTA 4OD4A 4CSAA 4BEJA 4QIIA 3KL4A 4BPMA 4ELWA 3QVYA 3JRMO 4LDKA 2LFFA 2EPLX 1HE1A 1O5HA 3M15A 4MVZA 3PDMP 4G7OF 2H8AA 5L0GA 3ZSUA 2QY9A 3DAFA 4EBBA 3EZHA 4IJJA 4BJ5A 3OWTA 1CPRA 2FBMA 4P9FA 2L6GA 1H9GA 3ITFA 4AL0A 3PMRA 2XL4A 5BQIA 4X0RA 4JTAB 1ZYRF 2YL3A 3H02A 3EPVA 2J0XA 2Q3TA 5HSWA 2XL6A 3ATPA 2KGOA 3L8JA 3A11A 2YL7A 4JYLA 4IAQA 1YVIA 1M2VB 4YL0A 1FFTC 4N06A 3KKBA 4KBLA 2IXOA 4XTKA 1BBHA 1SF8A 4YWQA 3NYJA 1M56C 3U9MA 3V5YA 2CDQA 5JP7A 1M2OA 1QLEC 3WHNA 1OCRC 2EIJC 1HZDA 2OJQA 2VB6A 2VX2A 3RQFA 2EILC 1E86A 1WWPA 4PR9A 1T01A 2P7VA 2R7UA 5EGYA 1JRAA 1MNDA 3ABLC 2LIGA 3RVYA 5FCLA 2HV6A 3RQEA 1RCPA 2MYSA 2JPUA 2OCCC 4GYTA 3VM6A 3NG1A 4PFOA 1BR4A 3LEVA 3TULA 1I4YA 3ZQYA 3AQCA 3UMIA 1V74B 5F5FA 3IPMO 3GM1A 3TOLA 4C7OB 5A6JA 3SXZA 3EHNA 1MNEA 1EI7A 5T3WA 4C3BA 1OW8A 256BA 3I47A 4O7GA 5JBXA 3ZTZA 2OG2A 4W8PA 1AUEA 1U89A 1NG1A 2A68F 1GGQA 2J9WA 4NEKA 4LDRA 4XEVA 2YLDA 3HNIA 4A4AA 4QI2A 2CGEA 2CCYA 5DS6A 2WB7A 1XWJA 2V3CC 2IM8A 5JSLA 2ZQRA 2L7AA 3GEEA 2R7SA 2F6QA 4CDVA 5EHHA 1OW6A 3C7JA 3DJNB 4LLEA 4MVSA 1UX4A 3LEOA 3JTLO 1JOGA 2QQ3A 1E2XA 2I8BA 4KI2A 2XLHA 3M4CA 2L6FA 3B0UX 1VTMP 2ETSA 4BJ6A 3A4LA 3LJBA 1PD0A 2L9JA 3I5QA 3JCUQ 4OIOF 5L0CA 2JD3A 1B68A 4LLCA 1D1CA 4MTFA 3R9TA 1N1CA 2CW0F 3K33A 1LVKA 3CQZA 1E84A 1FFHA 4Q5SF 4U5CE 2O9XA 5L0FA 1Z63A 3M4BA 4GEHB 3RYLA 4CS9C 3L8IA 4PACA 2HUJA 3KPHA 1H7IA 2NG1A 2W45A 4UDVA 3QXIA 2B0JA 5KYYA 2GDCA 2X51A 4XPWA 2A0UA 4U5BE 4F4BA 4YL3A 3SWXA 3C8GA 3U8VA 1EKYA 2FFHA 2V26A 3CAXA 3N24A 3JZ0A 2XRHA 1Q0FA 1YA9A 4ELXA 3EGDA 3PHF2 3US6A 4WABA 3AG3C 2MHRA 1WGWA 1A7VA 1YYXA 2ZPAA 2YWAA 2J7PA 2G3VA 3KYJA 4CS8A 4RD9A 3LAYA 4E0IA 4EIYA 2R7RA 4N6CA 2YZSA 5L3QA 2D4UA 4MVUA 4C3EA 5B1AC 3EJNA 3GORA 3POVA 3UGPA 3GANA 2HMZA 2PNOA 4CDYA 5KYUB 1MMGA 3IRBA 1A41A 1TWGA 3ZTMA 2LD6A 4KNPA 4Z9IA 3O6XA 2J9VA 2R02A 3SP1A 4GQHA 3QXZA 3J06A 4D4XA 2CNWD 1WZ8A 1OR3A 1J8MF 1TFKB 3ADCA 4E18A 5CIVA 2L81A 1KU2A 4FZWC 4DVYP 4JCSA 4FX5A 2GAQA 4Z9JA 5B3IA 1RKEB 2RSEB 5JUAA 1QSPA 1Y64B 3ECSA 4O79A 3SXYA 2QUPA 3RSIA 4EBJA 3K1HA 2Q4FA 2XS1A 4JTCB 4MNDA 3R7CA 4U18A 2NSFA 2R25A 1WOLA 3DE8A 5BQHA 4IZBA 4OINF 1L7CA 3ZQVA 4KNVA 2ZXOA 3B0PA 1G4US 1HMDA 2XLMA 2KQ9A 2ZXRA 3T9OA 3FVYA 3M1CB 1VYKA 3CZ6A 5T1DB 4IZDA 3IQ6A 3WODF 4XEFA 1HW1A 3ABKC 4FWVA 2W9YA 3RKOF 3V5ZA 1YZCA 5JT4A 3W8IB 1T6IA 3TLFA 1FNTc 1U6HA 3QW1A 4H54A 1M6TA 1ST6A 5L0JA 3LLIA 3PCVA 3G4ZA 4NC3A 3S27A 3U3FA 1ZW3A 4JIOA 4QIJA 1VMAA 2JX0A 3JYYA 2J8WA 4PJNA 4AX2A 1O3UA 4ELSA 2HSBA 3DXJF 1Q0MA 1EA8A 2DYRC 4IAOA 4MW8A 2NUPB 1Q0DA 2OJED 3V7OA 1UFBA 5KYXA 1PCXA 5A6KA 3T88A 2C03A 1TWCA 2XXAA 1APCA 4I4ZA 4K0DA 1JPNA 2WZLA 4FAPB 3W2WA 2P1AA 3I4UA 2ICWG 4I42A 3VF0A 1NZYA 3W4YA 3AQBA 3LLKA 1LI7A 3S9OA 2NUTB 2Y3DA 2EPKX 3SXKA 4G7ZF 2QE9A 3EFOA 2Y39A 1ZW2A 1JR8A 4U5EE 1D0ZA 1FTSA 1OKKA 3JSEO 1ZZPA 5B3SC 1PD1A 3SLLA 4JFCA 2WVNA 3EH2A 1RXQA 1CPQA 3ADBA 3QK8A 3DM5A 3RF3A 2R7OA 4MTOA 1D0YA 4DRHB 1LS4A 3R9SA 4PJLA 1VLTA 2XLVA 4CBEA 4U9EA 1ZVZA 3EFOB 2YKZA 1I5NA 1BR1A 2GFHA 4DRJB 3AG4C 5L3VA 2PBEA 1UX5A 1HW2A 3EG9A 4JKVA 3VAYA 3H2VA 4CS9A 2KK1A 2A0BA 2LQGA 3HNLA 3BRJA 2KNHA 4MOUA 1C03A 4DRIB 3FMSA 3GWNA 3K1IC 5T3TA 2W4BA 5TJ5E 4MVQA 1T5OA 5E3CA 2QNLA 1CGME 3ADDA 1QKRA 3Q6NA 1ZHXA 3VYWA 4IWBA 4OIQF 2B0HA 3Q0GA 3L34A 5DQZA 2YLIA 2J45A 4JJGA 3NYLA 2PBPA 3AOUA 4JJFA 3DZAA 2R7TA 1Q52A 3OC7A 3MFNA 1LPEA 2OKUA 3IHUA 1WN0A 3O39A 1EF9A 4U9DA 1RKCA 3CEXA 3X1OA 3DE9A 1G5ZA 4U19A 3TJ6A 2DB4A 5BUOA 4DVZA 2LP4A 4YN0B 2KC3A 2Y3BA 2HKVA 3NKDA 3KYIA 1JMWA 4G78A 2EIMC 2UUIA 5EK0A 1ORJA 1FMVA 4CSAC 4NNQA 1OCCC 4I44A 3DAGA 1EF8A 4EBKA 1NSGB 1V4AA 3K6BA 5DS5A 3S29A 3FAJA 3QZCA 4OLQA 3IQTA 4ULVA 1NU7D 3Q6MA 1QZXA 3QW0A 3A4MA 1IZMA 1MMAA 2PFDA 1UG7A 4XEKA 3ZDLA 1IW7F 4CIHA 4JTDB 1OXKA 4JVSA 3GEHA 2OQMA 4NTFA 2A69F 2HS5A 4ZU2A 3HLZA 2R7XA 1H9TA 4BJ5C 1E83A 4O6NA 3AM1A 3O10A 5A6BD 3S28A 1S05A 4NCQA 1T9KA 2HJMA 3EH1A 3N2ZB 3QVZA 3TOMA 2IYLD 4PJJA 1VLSA 1MMNA 4U5GA 4ZLDA 4QDLA 4IGGA 3S84A 3B9QA 4U5HA 4CDAA 4YJWA 1CGOA 2GA0A 4NQFA 4E0HA 2DI3A 1QPUA 3WAQA 5CI8A 1SR2A 4Q4ZF 5KYNA 2P0NA 1TKNA 3OEOA 3LS1A 1TWAA 2EPNA 2XLEA 3E70C 1J8YF 4RDAA 4HEAJ 1T6UA 4DXWA 4AK9A 3GODA 3VRCA 1SZIA 1Z23A 4U1AA 1Y6DA 1D1AA 4CJOA 5D92A 1LS1A 3DJUB 3FOPA 5KYYB 3EZIA 2NPUA 4KNWA 3T6GB 2QLAA 4PJMA 2LFDA 1LM3B 1NZEA 1MJ3A 2FW2A 3NYMA 1OCZC 3NRHA 3C8ZA 3C8GB 1OW7A 2PF4E 4CIPA 2BE5F 3NMIA 3EQLF 2YHSA 3U9JA 1DOWA 4DBRA 3EGDB 1QQ3A 5F5HA 4AL1A 1TQGA 2Q00A 2XL8A 4L6RA 3JRTA 2HFIA 1XZPA 1MMDA 3O55A 1LI5A 5L0HA 1BR2A 1LKXA 4ZLCA 2PX3A 3KH2A 2WVOA 3UMKA 1ZHWA 3L0IA 3KMIA 2Y69C 3MYIA 4J32B 4JCZA 2J9BA 1OR2A 3ZVRA 3CSKA 4OIPF 2XS8A 3AG2C 4AE4A 3ABMC 2YQYA 1D0XA 4MQ9F 3ZG1A 4DJ9A 2ASRA 3W8HA 4BJ6C 3DKAA 2HJ3A 1I4ZA 3LNRA 3HRXA 1FR0A 3ZWIA 4I3MA 3MX3A 3UNGC 4K2NA 4OG1A 1YZAA 1WATA 5JLIA 5COFA 5KYWA 1Q0KA 1W2WA 5CI9A 1OCOC 4DOZA 1BZ4A 2XSEA 2OOCA 2EJ5A 4PK4A 1XZQA 2H7VC 1RJMA 5L0DA 3K66A 4E17A 5F28E 3W8HB 5E33A 1ZHZA 2R9RB 3RH3A 2KYHA 4KC9A 1PV3A 3DMDA 3JT1A 2J9UA 5B1BC 4HFFB 2WVQA 4LACB 3ASNC 3TQOA 2R03A 3C62A 1EQ1A 4Q7CA 4C3DA 1VB5A 5JRAA 4JC7A 2CNWA 3S90A 1A7DA 2PX0A 3SNHA 2Y3GA 2CYDA 4MW3A 4MVOA 4H4KC 1DCIA 3Q0JA 2R7VA 4IRUA 3JYHA 4CS8C 2D5RB 4CJGA 1NU9C 3HKKA 1OXBA 2VCBA 3HNKA 4ER9A 3M79A 4E7SA 3NDBB 3C63A 4BJ1A 2OEVA 4BG0A 4P6IC 2YRFA 2C04A 3LUTB 3NMKA 4N4WA 4IARA 5A69A 4LDQA 3F46A 4K7BA 1RMVA 5DLJA 1V54C 3SZRA 2UZFA 3G50A 3MYFA 4IB4A 5KYXB 1M57C 1K40A 4WJ0A 4QI0A 2XM4A 2ZD9A 1ZHYA 3ASOC 2XXAB 1G8XA 2R05A 2ZQQA 2PPYA 1M2VA 3AG1C 5AC4A 4WGZA 3LS0A 5JVEA 3TD7A 1NZYB 1Q51A 2W4MA 1DUBA 2KJGA 1YA7O 2XLWA 2NSGA 2ZXWC 2Z15A 4ANJA 4HFKB 3LESA 5E3AA 4XPYA 1YAUO 1R5ID 2AU5A 3HJCA 2OEXA 4MI2A 3MLGA 4B6IA 2AVKA 2HV7A 3O4XE 3UGOA 3EHMA 4J7YA 1TR2A 5COGA 2GWWA 3FDQA 2IBFA 1YYJA 1QVXA 1HMOA 1HE9A 2Q9AA 2YEVA 2WL8A 1OQCA 4W8KA 4HE8D 4PFPA 2Y3HA 3Q1TA 4M63A 1DOVA 1LE4A 4C7OA 3U3BA 3GM3A 1UIYA 1R4TA 4MS2A 4JE9A 4CS7A 3EG9B 2HZ8A 2RD9A 4OIRF 1LIHA 2Q7RA 3QTHA 2TMVP 1A7EA 3ZIBA 1GS9A 3RQGA 2DYSC 4WCZA 2LCHA 3HTKC 3RFYA 5A6AA 5D91A 4Z9HA 2GTRA 2OU6A 1MQVA 2R7QA 4F47A 2A6EF 5L0IA 3H2UA 4LERA 4JEAA 4CX9A 3UMHA 3AGTA 3N0TA 1L3PA 1RJ9A 2AWYA 2DUBA 1JPJA 4EMLA 3C8GD 3DWWA 3NMJA 2YLGA 4I1OB 1NLXA 3LNMB 4NTBA 2BC5A 3FAPB 1FMWA 2KSFA 4JW1A 1KTMA 2J46A 4I1MA 3F47A 1YDIA 1ORSC 3T4RA 4EUKB 4FZWA 3AGUA 2J7PD 1Z7Qc 5DS4A 3GM2A 2PP4A 4A2NB 4U5DE 1Y4CA 2R7WA 1RJ9B 3FXHA 2J0WA 4XLPF 4IZCA 1VYIA 1T6QA 2AWCA 4GEHA 4XLNF 3IQCA 3RIPA 4MTGA 4NTAA 2YVKA 1CGNA 3FHDA 1NBBA 2YL0A 3RW0A 1S7ZA 4EWCA 1JXZA 3E9VA 2P61A 3TK0A 1VOMA 2VH3A 3Q7LA 1SMYF 3Q7GA 3BEHA
chains in the Genus database with same CATH topology
1WOLA 1WWPA 2L6FA 2KK1A 2YWAA 3C18A 4NNQA 3BRJA 4EBKA 1V4AA 3A4LA 1K04A 3C8GD 1K05A 2LK4A 3RQEA 2JPUA 3S9OA 3O4XE 3A4MA 3TULA 1KTMA 4XEFA 3ADDA 4XEKA 3GM1A 3W8IB 2L6GA 3IRBA 1ZZPA 1QVXA 1OW8A 4GEHB 3C8GB 1OW7A 3GM2A 3L8IA 3AM1A 3ADBA 3O10A 3L8JA 3ADCA 3U3FA 1KNYA 3A4NA 3GM3A 4XEVA 2L6HA 3AJMA 2JX0A 1RJMA 3JYYA 3K7DA 3MFNA 2P63A 3C8GA 1K40A 1O3UA 2Q00A 2HSBA 3B71A 5F28E 3W8HB 1Y64B 3RQGA 4R32A 3JZ0A 1OW6A 3U0CA 4EBJA 1PV3A 4NQFA 2PBEA 1UX5A 1UFBA 1UX4A 1JOGA 1WTYA 3RQFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q00 A;  2HSB A;  3B71 A;  3S9O A;  1WOL A;  1WWP A;  2L6F A;  3GM2 A;  3L8I A;  2KK1 A;  5F28 E;  3TUL A;  3W8H B;  4XEF A;  1KTM A;  2YWA A;  3C18 A;  3RQG A;  4R32 A;  3O10 A;  3L8J A;  3JZ0 A;  1OW6 A;  3U0C A;  4EBJ A;  1K40 A;  3BRJ A;  4XEK A;  3GM1 A;  1PV3 A;  4EBK A;  3W8I B;  3U3F A;  1KNY A;  1V4A A;  4NQF A;  2L6G A;  1K04 A;  3GM3 A;  4XEV A;  2L6H A;  3AJM A;  2JX0 A;  2PBE A;  3C8G D;  1K05 A;  1UFB A;  1QVX A;  1ZZP A;  2LK4 A;  3JYY A;  1OW8 A;  3K7D A;  3MFN A;  3RQE A;  1JOG A;  1WTY A;  3C8G A;  3RQF A;  2JPU A;  4GEH B;  3C8G B;  1OW7 A;  1O3U A; 
#chains in the Genus database with same CATH topology
 1F1M A;  2BL2 A;  3DM9 B;  3WG7 C;  2G62 A;  3C18 A;  2QTV A;  4YK5 A;  3HIN A;  3NKE A;  2HSQ A;  3SYN A;  3TRR A;  2EIK C;  5HV9 A;  3OA1 A;  4G0H A;  2LK4 A;  1TWH A;  4D4N A;  1C17 M;  1C02 A;  4J7T A;  2F22 A;  3U2L A;  3T89 A;  2KW3 C;  1JAF A;  4MVR A;  4DBQ A;  1E85 A;  2A6H F;  1VK5 A;  4OD5 A;  3JSZ A;  2IEX A;  4JUR I;  2XLD A;  2P6V A;  2G3K A;  1G4W R;  5AGF A;  1ZU4 A;  3B0V C;  2DGJ A;  1Q0G A;  3H65 A;  5GPG B;  2M4E A;  2UUH A;  1ORY A;  2XLO A;  3FOO A;  2XM0 A;  1GQA A;  2X0C A;  5KYU A;  4ULW A;  1Z5Z A;  5AC5 A;  1O87 A;  1TFO B;  2L6H A;  3FDU A;  5JBW A;  4YT4 A;  5KJP A;  3MBG A;  4J30 B;  4JOT A;  2EIN C;  4NY3 A;  1YAR O;  1FAP B;  4R32 A;  4K3W A;  3U0C A;  2Q9C A;  2HMQ A;  2YL1 A;  3DI5 A;  1RKE A;  3GWL A;  4U5F E;  4BEM J;  4FJW D;  4N6H A;  3V5X A;  3R2P A;  5A6B A;  1LE2 A;  1U0B B;  2MWQ A;  2H7O A;  1K05 A;  1AVO B;  5DQT A;  1NFN A;  3H81 A;  4O6Y A;  4MVM A;  5COM A;  3W2V A;  1V55 C;  3IQ5 A;  2FAP B;  2IXM A;  2I15 A;  3EGX A;  2VCA A;  3U8P A;  3B29 A;  5FZT A;  5K0I A;  4YT5 A;  3G4X A;  4XWJ A;  4YT8 A;  4P9T A;  4ONS A;  5IY5 C;  2LSE A;  2IXN A;  4JRZ A;  3UR3 C;  5JS5 A;  2ZXP A;  3I5P A;  3W8I A;  1D1B A;  3P5M A;  4G7H F;  1H6G A;  1KNY A;  3A4N A;  3AJM A;  2WZF A;  3K7D A;  2P63 A;  3HNJ A;  4JZA A;  3TJ5 A;  1AEP A;  3IEE A;  1NFO A;  4FES A;  3EGX B;  3MYB A;  3T6J A;  4I52 A;  1OKK D;  2IOQ A;  5E2Q A;  3GEI A;  2IXP A;  2VCC A;  3K1I A;  2M64 A;  1WTY A;  1YJG A;  4AE4 B;  3X2Q C;  1Z6A A;  1RJN A;  2EPM X;  1Z3I X;  2NUP A;  4RBN A;  5C9G A;  4E7Z A;  4EHP A;  4XPX A;  1YLM A;  2AP3 A;  2H7B A;  3SEO A;  3MOY A;  4EKW A;  5BQG A;  3DD7 A;  1K04 A;  2FGY A;  1HY5 A;  2VAS A;  5KYW B;  4XQ1 A;  3ZC4 A;  3L1M A;  2WZG A;  1SYQ A;  1GM5 A;  2VRE A;  3U2M A;  3G64 A;  3S0X A;  3T8A A;  5DVW A;  4YL1 A;  3KQF A;  3T6B A;  3U5S A;  2NUT A;  4BJT A;  2Q9B A;  2HW5 A;  3PZK A;  3A9C A;  4JEB A;  4WGY A;  2EPO A;  4JCH A;  4O6M A;  1A0B A;  3RVZ A;  2A1D D;  3QMK A;  1BDJ B;  2VC9 A;  1EY3 A;  4JWV A;  1WAS A;  4K1O A;  4YT2 A;  3B71 A;  3R0O A;  3SXM A;  2E87 A;  1ZU5 A;  1ZHT A;  4OD4 A;  4CSA A;  4BEJ A;  4QII A;  3KL4 A;  4BPM A;  4ELW A;  3QVY A;  3JRM O;  4LDK A;  2LFF A;  2EPL X;  1HE1 A;  1O5H A;  3M15 A;  4MVZ A;  3PDM P;  4G7O F;  2H8A A;  5L0G A;  3ZSU A;  2QY9 A;  3DAF A;  4EBB A;  3EZH A;  4IJJ A;  4BJ5 A;  3OWT A;  1CPR A;  2FBM A;  4P9F A;  2L6G A;  1H9G A;  3ITF A;  4AL0 A;  3PMR A;  2XL4 A;  5BQI A;  4X0R A;  4JTA B;  1ZYR F;  2YL3 A;  3H02 A;  3EPV A;  2J0X A;  2Q3T A;  5HSW A;  2XL6 A;  3ATP A;  2KGO A;  3L8J A;  3A11 A;  2YL7 A;  4JYL A;  4IAQ A;  1YVI A;  1M2V B;  4YL0 A;  1FFT C;  4N06 A;  3KKB A;  4KBL A;  2IXO A;  4XTK A;  1BBH A;  1SF8 A;  4YWQ A;  3NYJ A;  1M56 C;  3U9M A;  3V5Y A;  2CDQ A;  5JP7 A;  1M2O A;  1QLE C;  3WHN A;  1OCR C;  2EIJ C;  1HZD A;  2OJQ A;  2VB6 A;  2VX2 A;  3RQF A;  2EIL C;  1E86 A;  1WWP A;  4PR9 A;  1T01 A;  2P7V A;  2R7U A;  5EGY A;  1JRA A;  1MND A;  3ABL C;  2LIG A;  3RVY A;  5FCL A;  2HV6 A;  3RQE A;  1RCP A;  2MYS A;  2JPU A;  2OCC C;  4GYT A;  3VM6 A;  3NG1 A;  4PFO A;  1BR4 A;  3LEV A;  3TUL A;  1I4Y A;  3ZQY A;  3AQC A;  3UMI A;  1V74 B;  5F5F A;  3IPM O;  3GM1 A;  3TOL A;  4C7O B;  5A6J A;  3SXZ A;  3EHN A;  1MNE A;  1EI7 A;  5T3W A;  4C3B A;  1OW8 A;  256B A;  3I47 A;  4O7G A;  5JBX A;  3ZTZ A;  2OG2 A;  4W8P A;  1AUE A;  1U89 A;  1NG1 A;  2A68 F;  1GGQ A;  2J9W A;  4NEK A;  4LDR A;  4XEV A;  2YLD A;  3HNI A;  4A4A A;  4QI2 A;  2CGE A;  2CCY A;  5DS6 A;  2WB7 A;  1XWJ A;  2V3C C;  2IM8 A;  5JSL A;  2ZQR A;  2L7A A;  3GEE A;  2R7S A;  2F6Q A;  4CDV A;  5EHH A;  1OW6 A;  3C7J A;  3DJN B;  4LLE A;  4MVS A;  1UX4 A;  3LEO A;  3JTL O;  1JOG A;  2QQ3 A;  1E2X A;  2I8B A;  4KI2 A;  2XLH A;  3M4C A;  2L6F A;  3B0U X;  1VTM P;  2ETS A;  4BJ6 A;  3A4L A;  3LJB A;  1PD0 A;  2L9J A;  3I5Q A;  3JCU Q;  4OIO F;  5L0C A;  2JD3 A;  1B68 A;  4LLC A;  1D1C A;  4MTF A;  3R9T A;  1N1C A;  2CW0 F;  3K33 A;  1LVK A;  3CQZ A;  1E84 A;  1FFH A;  4Q5S F;  4U5C E;  2O9X A;  5L0F A;  1Z63 A;  3M4B A;  4GEH B;  3RYL A;  4CS9 C;  3L8I A;  4PAC A;  2HUJ A;  3KPH A;  1H7I A;  2NG1 A;  2W45 A;  4UDV A;  3QXI A;  2B0J A;  5KYY A;  2GDC A;  2X51 A;  4XPW A;  2A0U A;  4U5B E;  4F4B A;  4YL3 A;  3SWX A;  3C8G A;  3U8V A;  1EKY A;  2FFH A;  2V26 A;  3CAX A;  3N24 A;  3JZ0 A;  2XRH A;  1Q0F A;  1YA9 A;  4ELX A;  3EGD A;  3PHF 2;  3US6 A;  4WAB A;  3AG3 C;  2MHR A;  1WGW A;  1A7V A;  1YYX A;  2ZPA A;  2YWA A;  2J7P A;  2G3V A;  3KYJ A;  4CS8 A;  4RD9 A;  3LAY A;  4E0I A;  4EIY A;  2R7R A;  4N6C A;  2YZS A;  5L3Q A;  2D4U A;  4MVU A;  4C3E A;  5B1A C;  3EJN A;  3GOR A;  3POV A;  3UGP A;  3GAN A;  2HMZ A;  2PNO A;  4CDY A;  5KYU B;  1MMG A;  3IRB A;  1A41 A;  1TWG A;  3ZTM A;  2LD6 A;  4KNP A;  4Z9I A;  3O6X A;  2J9V A;  2R02 A;  3SP1 A;  4GQH A;  3QXZ A;  3J06 A;  4D4X A;  2CNW D;  1WZ8 A;  1OR3 A;  1J8M F;  1TFK B;  3ADC A;  4E18 A;  5CIV A;  2L81 A;  1KU2 A;  4FZW C;  4DVY P;  4JCS A;  4FX5 A;  2GAQ A;  4Z9J A;  5B3I A;  1RKE B;  2RSE B;  5JUA A;  1QSP A;  1Y64 B;  3ECS A;  4O79 A;  3SXY A;  2QUP A;  3RSI A;  4EBJ A;  3K1H A;  2Q4F A;  2XS1 A;  4JTC B;  4MND A;  3R7C A;  4U18 A;  2NSF A;  2R25 A;  1WOL A;  3DE8 A;  5BQH A;  4IZB A;  4OIN F;  1L7C A;  3ZQV A;  4KNV A;  2ZXO A;  3B0P A;  1G4U S;  1HMD A;  2XLM A;  2KQ9 A;  2ZXR A;  3T9O A;  3FVY A;  3M1C B;  1VYK A;  3CZ6 A;  5T1D B;  4IZD A;  3IQ6 A;  3WOD F;  4XEF A;  1HW1 A;  3ABK C;  4FWV A;  2W9Y A;  3RKO F;  3V5Z A;  1YZC A;  5JT4 A;  3W8I B;  1T6I A;  3TLF A;  1FNT c;  1U6H A;  3QW1 A;  4H54 A;  1M6T A;  1ST6 A;  5L0J A;  3LLI A;  3PCV A;  3G4Z A;  4NC3 A;  3S27 A;  3U3F A;  1ZW3 A;  4JIO A;  4QIJ A;  1VMA A;  2JX0 A;  3JYY A;  2J8W A;  4PJN A;  4AX2 A;  1O3U A;  4ELS A;  2HSB A;  3DXJ F;  1Q0M A;  1EA8 A;  2DYR C;  4IAO A;  4MW8 A;  2NUP B;  1Q0D A;  2OJE D;  3V7O A;  1UFB A;  5KYX A;  1PCX A;  5A6K A;  3T88 A;  2C03 A;  1TWC A;  2XXA A;  1APC A;  4I4Z A;  4K0D A;  1JPN A;  2WZL A;  4FAP B;  3W2W A;  2P1A A;  3I4U A;  2ICW G;  4I42 A;  3VF0 A;  1NZY A;  3W4Y A;  3AQB A;  3LLK A;  1LI7 A;  3S9O A;  2NUT B;  2Y3D A;  2EPK X;  3SXK A;  4G7Z F;  2QE9 A;  3EFO A;  2Y39 A;  1ZW2 A;  1JR8 A;  4U5E E;  1D0Z A;  1FTS A;  1OKK A;  3JSE O;  1ZZP A;  5B3S C;  1PD1 A;  3SLL A;  4JFC A;  2WVN A;  3EH2 A;  1RXQ A;  1CPQ A;  3ADB A;  3QK8 A;  3DM5 A;  3RF3 A;  2R7O A;  4MTO A;  1D0Y A;  4DRH B;  1LS4 A;  3R9S A;  4PJL A;  1VLT A;  2XLV A;  4CBE A;  4U9E A;  1ZVZ A;  3EFO B;  2YKZ A;  1I5N A;  1BR1 A;  2GFH A;  4DRJ B;  3AG4 C;  5L3V A;  2PBE A;  1UX5 A;  1HW2 A;  3EG9 A;  4JKV A;  3VAY A;  3H2V A;  4CS9 A;  2KK1 A;  2A0B A;  2LQG A;  3HNL A;  3BRJ A;  2KNH A;  4MOU A;  1C03 A;  4DRI B;  3FMS A;  3GWN A;  3K1I C;  5T3T A;  2W4B A;  5TJ5 E;  4MVQ A;  1T5O A;  5E3C A;  2QNL A;  1CGM E;  3ADD A;  1QKR A;  3Q6N A;  1ZHX A;  3VYW A;  4IWB A;  4OIQ F;  2B0H A;  3Q0G A;  3L34 A;  5DQZ A;  2YLI A;  2J45 A;  4JJG A;  3NYL A;  2PBP A;  3AOU A;  4JJF A;  3DZA A;  2R7T A;  1Q52 A;  3OC7 A;  3MFN A;  1LPE A;  2OKU A;  3IHU A;  1WN0 A;  3O39 A;  1EF9 A;  4U9D A;  1RKC A;  3CEX A;  3X1O A;  3DE9 A;  1G5Z A;  4U19 A;  3TJ6 A;  2DB4 A;  5BUO A;  4DVZ A;  2LP4 A;  4YN0 B;  2KC3 A;  2Y3B A;  2HKV A;  3NKD A;  3KYI A;  1JMW A;  4G78 A;  2EIM C;  2UUI A;  5EK0 A;  1ORJ A;  1FMV A;  4CSA C;  4NNQ A;  1OCC C;  4I44 A;  3DAG A;  1EF8 A;  4EBK A;  1NSG B;  1V4A A;  3K6B A;  5DS5 A;  3S29 A;  3FAJ A;  3QZC A;  4OLQ A;  3IQT A;  4ULV A;  1NU7 D;  3Q6M A;  1QZX A;  3QW0 A;  3A4M A;  1IZM A;  1MMA A;  2PFD A;  1UG7 A;  4XEK A;  3ZDL A;  1IW7 F;  4CIH A;  4JTD B;  1OXK A;  4JVS A;  3GEH A;  2OQM A;  4NTF A;  2A69 F;  2HS5 A;  4ZU2 A;  3HLZ A;  2R7X A;  1H9T A;  4BJ5 C;  1E83 A;  4O6N A;  3AM1 A;  3O10 A;  5A6B D;  3S28 A;  1S05 A;  4NCQ A;  1T9K A;  2HJM A;  3EH1 A;  3N2Z B;  3QVZ A;  3TOM A;  2IYL D;  4PJJ A;  1VLS A;  1MMN A;  4U5G A;  4ZLD A;  4QDL A;  4IGG A;  3S84 A;  3B9Q A;  4U5H A;  4CDA A;  4YJW A;  1CGO A;  2GA0 A;  4NQF A;  4E0H A;  2DI3 A;  1QPU A;  3WAQ A;  5CI8 A;  1SR2 A;  4Q4Z F;  5KYN A;  2P0N A;  1TKN A;  3OEO A;  3LS1 A;  1TWA A;  2EPN A;  2XLE A;  3E70 C;  1J8Y F;  4RDA A;  4HEA J;  1T6U A;  4DXW A;  4AK9 A;  3GOD A;  3VRC A;  1SZI A;  1Z23 A;  4U1A A;  1Y6D A;  1D1A A;  4CJO A;  5D92 A;  1LS1 A;  3DJU B;  3FOP A;  5KYY B;  3EZI A;  2NPU A;  4KNW A;  3T6G B;  2QLA A;  4PJM A;  2LFD A;  1LM3 B;  1NZE A;  1MJ3 A;  2FW2 A;  3NYM A;  1OCZ C;  3NRH A;  3C8Z A;  3C8G B;  1OW7 A;  2PF4 E;  4CIP A;  2BE5 F;  3NMI A;  3EQL F;  2YHS A;  3U9J A;  1DOW A;  4DBR A;  3EGD B;  1QQ3 A;  5F5H A;  4AL1 A;  1TQG A;  2Q00 A;  2XL8 A;  4L6R A;  3JRT A;  2HFI A;  1XZP A;  1MMD A;  3O55 A;  1LI5 A;  5L0H A;  1BR2 A;  1LKX A;  4ZLC A;  2PX3 A;  3KH2 A;  2WVO A;  3UMK A;  1ZHW A;  3L0I A;  3KMI A;  2Y69 C;  3MYI A;  4J32 B;  4JCZ A;  2J9B A;  1OR2 A;  3ZVR A;  3CSK A;  4OIP F;  2XS8 A;  3AG2 C;  4AE4 A;  3ABM C;  2YQY A;  1D0X A;  4MQ9 F;  3ZG1 A;  4DJ9 A;  2ASR A;  3W8H A;  4BJ6 C;  3DKA A;  2HJ3 A;  1I4Z A;  3LNR A;  3HRX A;  1FR0 A;  3ZWI A;  4I3M A;  3MX3 A;  3UNG C;  4K2N A;  4OG1 A;  1YZA A;  1WAT A;  5JLI A;  5COF A;  5KYW A;  1Q0K A;  1W2W A;  5CI9 A;  1OCO C;  4DOZ A;  1BZ4 A;  2XSE A;  2OOC A;  2EJ5 A;  4PK4 A;  1XZQ A;  2H7V C;  1RJM A;  5L0D A;  3K66 A;  4E17 A;  5F28 E;  3W8H B;  5E33 A;  1ZHZ A;  2R9R B;  3RH3 A;  2KYH A;  4KC9 A;  1PV3 A;  3DMD A;  3JT1 A;  2J9U A;  5B1B C;  4HFF B;  2WVQ A;  4LAC B;  3ASN C;  3TQO A;  2R03 A;  3C62 A;  1EQ1 A;  4Q7C A;  4C3D A;  1VB5 A;  5JRA A;  4JC7 A;  2CNW A;  3S90 A;  1A7D A;  2PX0 A;  3SNH A;  2Y3G A;  2CYD A;  4MW3 A;  4MVO A;  4H4K C;  1DCI A;  3Q0J A;  2R7V A;  4IRU A;  3JYH A;  4CS8 C;  2D5R B;  4CJG A;  1NU9 C;  3HKK A;  1OXB A;  2VCB A;  3HNK A;  4ER9 A;  3M79 A;  4E7S A;  3NDB B;  3C63 A;  4BJ1 A;  2OEV A;  4BG0 A;  4P6I C;  2YRF A;  2C04 A;  3LUT B;  3NMK A;  4N4W A;  4IAR A;  5A69 A;  4LDQ A;  3F46 A;  4K7B A;  1RMV A;  5DLJ A;  1V54 C;  3SZR A;  2UZF A;  3G50 A;  3MYF A;  4IB4 A;  5KYX B;  1M57 C;  1K40 A;  4WJ0 A;  4QI0 A;  2XM4 A;  2ZD9 A;  1ZHY A;  3ASO C;  2XXA B;  1G8X A;  2R05 A;  2ZQQ A;  2PPY A;  1M2V A;  3AG1 C;  5AC4 A;  4WGZ A;  3LS0 A;  5JVE A;  3TD7 A;  1NZY B;  1Q51 A;  2W4M A;  1DUB A;  2KJG A;  1YA7 O;  2XLW A;  2NSG A;  2ZXW C;  2Z15 A;  4ANJ A;  4HFK B;  3LES A;  5E3A A;  4XPY A;  1YAU O;  1R5I D;  2AU5 A;  3HJC A;  2OEX A;  4MI2 A;  3MLG A;  4B6I A;  2AVK A;  2HV7 A;  3O4X E;  3UGO A;  3EHM A;  4J7Y A;  1TR2 A;  5COG A;  2GWW A;  3FDQ A;  2IBF A;  1YYJ A;  1QVX A;  1HMO A;  1HE9 A;  2Q9A A;  2YEV A;  2WL8 A;  1OQC A;  4W8K A;  4HE8 D;  4PFP A;  2Y3H A;  3Q1T A;  4M63 A;  1DOV A;  1LE4 A;  4C7O A;  3U3B A;  3GM3 A;  1UIY A;  1R4T A;  4MS2 A;  4JE9 A;  4CS7 A;  3EG9 B;  2HZ8 A;  2RD9 A;  4OIR F;  1LIH A;  2Q7R A;  3QTH A;  2TMV P;  1A7E A;  3ZIB A;  1GS9 A;  3RQG A;  2DYS C;  4WCZ A;  2LCH A;  3HTK C;  3RFY A;  5A6A A;  5D91 A;  4Z9H A;  2GTR A;  2OU6 A;  1MQV A;  2R7Q A;  4F47 A;  2A6E F;  5L0I A;  3H2U A;  4LER A;  4JEA A;  4CX9 A;  3UMH A;  3AGT A;  3N0T A;  1L3P A;  1RJ9 A;  2AWY A;  2DUB A;  1JPJ A;  4EML A;  3C8G D;  3DWW A;  3NMJ A;  2YLG A;  4I1O B;  1NLX A;  3LNM B;  4NTB A;  2BC5 A;  3FAP B;  1FMW A;  2KSF A;  4JW1 A;  1KTM A;  2J46 A;  4I1M A;  3F47 A;  1YDI A;  1ORS C;  3T4R A;  4EUK B;  4FZW A;  3AGU A;  2J7P D;  1Z7Q c;  5DS4 A;  3GM2 A;  2PP4 A;  4A2N B;  4U5D E;  1Y4C A;  2R7W A;  1RJ9 B;  3FXH A;  2J0W A;  4XLP F;  4IZC A;  1VYI A;  1T6Q A;  2AWC A;  4GEH A;  4XLN F;  3IQC A;  3RIP A;  4MTG A;  4NTA A;  2YVK A;  1CGN A;  3FHD A;  1NBB A;  2YL0 A;  3RW0 A;  1S7Z A;  4EWC A;  1JXZ A;  3E9V A;  2P61 A;  3TK0 A;  1VOM A;  2VH3 A;  3Q7L A;  1SMY F;  3Q7G A;  3BEH A; 
#chains in the Genus database with same CATH homology
 1WOL A;  1WWP A;  2L6F A;  2KK1 A;  2YWA A;  3C18 A;  4NNQ A;  3BRJ A;  4EBK A;  1V4A A;  3A4L A;  1K04 A;  3C8G D;  1K05 A;  2LK4 A;  3RQE A;  2JPU A;  3S9O A;  3O4X E;  3A4M A;  3TUL A;  1KTM A;  4XEF A;  3ADD A;  4XEK A;  3GM1 A;  3W8I B;  2L6G A;  3IRB A;  1ZZP A;  1QVX A;  1OW8 A;  4GEH B;  3C8G B;  1OW7 A;  3GM2 A;  3L8I A;  3AM1 A;  3ADB A;  3O10 A;  3L8J A;  3ADC A;  3U3F A;  1KNY A;  3A4N A;  3GM3 A;  4XEV A;  2L6H A;  3AJM A;  2JX0 A;  1RJM A;  3JYY A;  3K7D A;  3MFN A;  2P63 A;  3C8G A;  1K40 A;  1O3U A;  2Q00 A;  2HSB A;  3B71 A;  5F28 E;  3W8H B;  1Y64 B;  3RQG A;  4R32 A;  3JZ0 A;  1OW6 A;  3U0C A;  4EBJ A;  1PV3 A;  4NQF A;  2PBE A;  1UX5 A;  1UFB A;  1UX4 A;  1JOG A;  1WTY A;  3RQF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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