3L8IA

Crystal structure of ccm3, a cerebral cavernous malformation protein critical for vascular integrity
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
198
structure length
198
Chain Sequence
TSMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFVSANRLIHQTNLILQTFKTVA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Homo sapiens
publication title Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.
pubmed doi rcsb
molecule keywords Programmed cell death protein 10
total genus 74
structure length 198
sequence length 198
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2009-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06840 DUF1241 Protein of unknown function (DUF1241)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 3l8iA01
1.20.120.330 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Nucleotidyltransferases domain 2 3l8iA02
1WWPA 3JYYA 2Q00A 3AJMA 1QVXA 1KNYA 1WOLA 3W8IB 3MFNA 1KTMA 3C8GA 2JX0A 4EBJA 4R32A 2L6FA 2KK1A 3K7DA 3L8JA 2PBEA 3RQGA 1WTYA 3S9OA 4EBKA 3GM1A 2LK4A 1JOGA 1OW7A 2JPUA 1PV3A 1OW6A 3C18A 4NQFA 3TULA 1V4AA 1O3UA 1K05A 3U0CA 2L6GA 3C8GB 3RQFA 4GEHB 2HSBA 4XEFA 3BRJA 3C8GD 3W8HB 5F28E 3O10A 1K40A 3L8IA 1K04A 1OW8A 3GM2A 4XEVA 2YWAA 3GM3A 4XEKA 3JZ0A 3RQEA 3U3FA 3B71A 1UFBA 1ZZPA 2L6HA
chains in the Genus database with same CATH superfamily
4E0IA 4WJ0A 4AE4B 3GEHA 2NSFA 2J9WA 3FMSA 3TOMA 1OXKA 1ZU4A 5BQIA 3OA1A 5JT4A 2RSEB 5FCLA 2LCHA 4NCQA 3ZTZA 4M63A 1UX4A 2BE5F 4LLCA 1YA7O 3B29A 1NSGB 3T89A 1NBBA 1Y64B 4OIOF 4GQHA 3WG7C 2WZLA 3KMIA 2ICWG 2TMVP 1GS9A 3A4MA 2VCCA 3KL4A 2R7RA 1U89A 1MMDA 3JZ0A 2R7WA 3IQCA 2NUTB 4CIPA 2PBEA 4E0HA 1T5OA 2R7QA 1HY5A 4P9TA 2W4BA 2Y69C 1YA9A 1T9KA 2ZXWC 2Q00A 4XPYA 3MOYA 5AC4A 3IQ5A 2MHRA 4O6MA 2GFHA 4ULVA 3LJBA 1LS4A 4JCSA 2PP4A 2ZQRA 3JT1A 3LLIA 1OR2A 4U5EE 3SNHA 4JZAA 3HNKA 3DAGA 2HJ3A 3K1IA 2OKUA 4IRUA 3B0PA 2YL0A 3NRHA 3NMIA 1M2VA 3A9CA 4ONSA 3H65A 2A6HF 1OR3A 2HKVA 3IQTA 2GA0A 3OEOA 1K40A 2Q9BA 5F5FA 4PK4A 2NUPA 2VX2A 1KNYA 1W2WA 4G7ZF 3EHNA 3HNIA 1YAUO 2J7PD 4C3BA 3HKKA 2IOQA 2ZXRA 2Q7RA 3CSKA 1JRAA 1JPNA 2J0XA 3L1MA 2QY9A 4XWJA 4U5CE 2WZFA 1QSPA 3JYYA 1NZYA 3NKDA 3G4XA 1A41A 4LERA 3FDUA 2OG2A 5DS5A 3K7DA 5KYXB 2H7OA 1G4US 3ZIBA 5CI9A 1TWHA 3DWWA 3CEXA 3VRCA 3TOLA 3T6GB 3K33A 3O55A 3DAFA 4YL0A 4AL1A 3N2ZB 2H8AA 1QPUA 1M2OA 4UDVA 4ZLCA 1OCCC 1D0ZA 1J8MF 1SMYF 2ZQQA 3L0IA 2UUHA 1RMVA 5KJPA 2Q3TA 1I5NA 1D1AA 3AQCA 3PDMP 1E86A 3US6A 5D91A 2UZFA 2L7AA 3FOOA 1E2XA 3M79A 4BJ5C 1CPQA 2WB7A 4FWVA 2D4UA 4OINF 4KNVA 1Q52A 3E70C 5AC5A 4U9DA 1YLMA 5KYYA 2XL6A 2XXAA 1D0XA 4CSAC 4O7GA 1D1CA 4BG0A 1BBHA 4C7OB 3SXZA 3ZWIA 2OQMA 5JS5A 3K6BA 1V74B 5L0GA 2F22A 1TWGA 3TJ6A 1QQ3A 4OD5A 1YDIA 2FGYA 4NC3A 1GQAA 4JOTA 3LESA 3KYJA 4CIHA 2Z15A 1VYKA 2VCAA 1TKNA 3BEHA 2YL7A 4LDKA 3EGDA 2MWQA 5FZTA 5A6BD 1ZYRF 4NTBA 1A0BA 3WODF 3HRXA 1Q0FA 2VREA 2AWCA 2YLIA 4ANJA 3FAPB 3R9TA 4BJ6A 1Y6DA 2IXOA 5JRAA 3DE8A 5KYWB 2EIKC 1ZW3A 4N06A 1T6UA 4YWQA 5COMA 3F47A 3TD7A 4NTAA 256BA 2DYRC 2XSEA 3MX3A 3BRJA 3S27A 3GM3A 2PNOA 3EPVA 1E83A 3IEEA 1OQCA 2XLWA 1YJGA 1ZU5A 3SXMA 4ZLDA 2WVQA 1CPRA 4YT4A 3U2LA 3O10A 3KPHA 3LAYA 4K7BA 4WGYA 3TK0A 3G50A 5BQGA 1Z23A 3O39A 3U3BA 4CX9A 3LNMB 5L0DA 1LI5A 3FAJA 3S29A 4MVSA 1MNDA 2OOCA 4XTKA 3H02A 5JSLA 1OCZC 4E7SA 5JLIA 2MYSA 1UIYA 3SP1A 1LE2A 3DXJF 2RD9A 4U5GA 2P0NA 3M4CA 2GWWA 1Y4CA 1RJMA 5JBXA 2J9VA 4MQ9F 3T6JA 5DVWA 4DVZA 2KNHA 2OJQA 3SZRA 1PCXA 3A4LA 4MW3A 3EGXB 4CS8A 2OCCC 2OEXA 3JRTA 2PBPA 1GM5A 3IQ6A 2YEVA 2NG1A 5F5HA 1HE1A 1ORJA 1XZPA 2JD3A 2Y3BA 1LE4A 1H6GA 2OJED 3F46A 4MTOA 4XEFA 3C8GD 1RKEB 3NMJA 2OU6A 1YYJA 3O4XE 2Y3GA 3GANA 2L6HA 1B68A 3VYWA 1S7ZA 1RCPA 4EBBA 2KQ9A 4RBNA 3LLKA 3T9OA 3DZAA 4JVSA 3S90A 4GEHB 2G62A 2LD6A 2Y3HA 4PJLA 3U2MA 2X0CA 1E84A 4OIRF 2P7VA 4NTFA 3DM5A 4P6IC 2YLDA 4JEAA 3HINA 2V26A 2XLOA 3AQBA 3JCUQ 1Z63A 3C8GB 1FTSA 1RJ9B 2XLEA 3I47A 3IPMO 1ST6A 4I4ZA 2C04A 3RQGA 4YJWA 2XM0A 5COFA 1Z7Qc 2LQGA 1TWCA 3FVYA 1VMAA 2XLMA 5IY5C 3ABMC 3AOUA 5T3WA 4PACA 2UUIA 3MYFA 3DI5A 2YHSA 1K05A 3UMIA 2I8BA 4OIQF 5KYXA 2J46A 3NYMA 2R7VA 1V55C 2HJMA 2A68F 2AWYA 4YL3A 4JCZA 2R9RB 4WCZA 1T01A 3AGTA 1GGQA 1OW8A 3PZKA 1FMWA 1RXQA 3K66A 4G7HF 1WN0A 2L6FA 4EBKA 3QVYA 2H7VC 2GTRA 2CDQA 3KKBA 2QQ3A 3GORA 2BL2A 1HW2A 1WASA 3RQEA 4BJTA 3RYLA 4G78A 3ATPA 4JWVA 1NZEA 2EJ5A 5L0HA 2YL1A 3Q1TA 2KSFA 1JOGA 1OXBA 1OW6A 2LSEA 3A11A 4IAQA 2P1AA 5DS4A 4WABA 2WL8A 3U3FA 2J9BA 4MTGA 4PR9A 1QKRA 3PCVA 3VAYA 3L8JA 4I44A 1FFHA 3UGPA 1JMWA 1ORSC 1PV3A 2EINC 3VM6A 1C02A 2L6GA 4A2NB 2ZPAA 3W8HB 2HV6A 2A0UA 4QIJA 1J8YF 2CNWD 4I3MA 1OKKA 1FR0A 4CDYA 3JRMO 4Z9IA 5GPGB 5C9GA 5T1DB 3WHNA 1R4TA 2LIGA 4KNWA 2YKZA 3J06A 3Q0GA 1WGWA 1CGOA 4EWCA 2R05A 2JX0A 4P9FA 4N4WA 4D4NA 3FXHA 5DLJA 4I52A 4RD9A 3FDQA 4ELWA 4BEJA 1CGME 3SYNA 2R7SA 3P5MA 4MVMA 3G64A 1ZHXA 2A69F 3S0XA 2KYHA 3EFOA 2Q4FA 3U8VA 3JYHA 4FZWA 1EI7A 2AVKA 1IZMA 2HUJA 4PJJA 4FAPB 1NU9C 3K1IC 5KYNA 1UFBA 1LIHA 1C03A 1JXZA 5L0IA 4I1OB 2X51A 4BJ1A 3EHMA 1FNTc 3EJNA 2QLAA 2B0JA 1RJNA 4CDAA 1JPJA 5BUOA 5L0CA 3I5QA 1LVKA 3ITFA 1M57C 1MQVA 2KGOA 1TQGA 3Q0JA 3UR3C 1MMAA 5L3QA 3C18A 2JPUA 1L3PA 4B6IA 2LP4A 4CS7A 4MI2A 3L8IA 5DQZA 1WWPA 2HZ8A 3HLZA 1BZ4A 1A7DA 1G8XA 1NFNA 4YT2A 1QLEC 4JC7A 1EQ1A 2WZGA 5KYUB 2XL4A 1VYIA 2QNLA 3IRBA 3W8IA 4U1AA 3RQFA 3ABKC 2IXPA 3A4NA 1H9TA 1FMVA 4LDRA 4JE9A 4J32B 2D5RB 2HW5A 4ZU2A 3U8PA 3RSIA 3R7CA 3RKOF 2W4MA 2XLDA 5JP7A 4XPWA 2YRFA 1UG7A 3DJUB 4MS2A 4OD4A 2Q9CA 1PD0A 2IEXA 3W2WA 4K1OA 4IJJA 2L81A 1E85A 4G0HA 3KQFA 3C63A 3H81A 2WVNA 4AL0A 1M2VB 3DE9A 5T3TA 2EPLX 2HSBA 1R5ID 5AGFA 5B3IA 4NQFA 2IBFA 3S28A 4U5FE 3LUTB 2XS1A 1U6HA 2AP3A 1VB5A 3AG3C 2NUPB 4FESA 3R0OA 3RVYA 5HV9A 2VCBA 1I4YA 4XPXA 3AG4C 4U5DE 4DRIB 5BQHA 3EZIA 5JUAA 2CGEA 3MBGA 2P61A 2FBMA 3H2UA 4JIOA 4Z9HA 1Z3IX 3RVZA 1NZYB 1AUEA 2HS5A 2IXMA 5EK0A 2PX3A 3W4YA 1WATA 2YQYA 5E2QA 2ZXPA 3RIPA 2F6QA 2EPOA 1YZAA 3QW1A 1A7VA 3UGOA 4BPMA 2CW0F 4AE4A 3M15A 1LPEA 4CS9A 4JYLA 4U19A 1TR2A 3GM2A 4BJ6C 3AJMA 2Q9AA 3EZHA 1ZHYA 2EPMX 3UNGC 2I15A 2OEVA 3EQLF 4IAOA 4E17A 3DD7A 5EHHA 5HSWA 5L3VA 1SF8A 1EKYA 2W45A 2XRHA 4E7ZA 5A6AA 4OLQA 1VLTA 2FFHA 1CGNA 3B71A 1SYQA 3TRRA 1DOWA 3LEVA 4MOUA 4O6NA 2LFFA 4RDAA 5KYYB 2NUTA 2XXAB 1HW1A 1D0YA 1AVOB 2YL3A 1U0BB 1D1BA 3HJCA 4QI2A 3QTHA 2EIMC 1LM3B 2VH3A 2DGJA 3RH3A 4Q7CA 4HFKB 4MTFA 3QW0A 3FHDA 3U9MA 2R7UA 1VOMA 5L0JA 5CI8A 4EHPA 3EG9B 2FW2A 1BDJB 4XLPF 4PJMA 3SWXA 4XEVA 1V54C 3EGDB 5JBWA 2W9YA 2GAQA 4JEBA 4FJWD 3I4UA 5DS6A 1BR2A 2DUBA 5B1BC 2AU5A 3NMKA 3ECSA 3LEOA 2J9UA 4DVYP 1RKCA 3R2PA 2EILC 1G4WR 4JTDB 4CS8C 2QE9A 3ADDA 3DM9B 2YVKA 3Q7GA 2GDCA 3QK8A 2E87A 3ZC4A 4IGGA 4ELSA 3NKEA 2M64A 3TJ5A 4EUKB 3TLFA 1JR8A 2IYLD 1H7IA 4NNQA 2DB4A 3EH1A 3X1OA 4EBJA 3EH2A 4YT5A 4BEMJ 1ZVZA 3NG1A 1MJ3A 2QUPA 3AGUA 1G5ZA 2PX0A 4U5BE 4KI2A 1EF8A 1SR2A 3C8ZA 4IB4A 3S9OA 1OCOC 4KNPA 4F4BA 3QXIA 2CYDA 2PF4E 2J7PA 4IARA 1YARO 3CQZA 2QTVA 1TWAA 4HE8D 4R32A 3M4BA 2J45A 4D4XA 4MVZA 4HFFB 4YT8A 2Y39A 3I5PA 3PMRA 4LACB 4XEKA 4ELXA 3NYLA 2EPKX 3HNJA 3ZG1A 5CIVA 2PPYA 2HFIA 4MW8A 3GODA 3GWLA 4Z9JA 4U18A 3ZQVA 3UMHA 4C7OA 4XLNF 5KYUA 1Q51A 1L7CA 1APCA 1H9GA 3O6XA 1I4ZA 4LLEA 3RF3A 1DOVA 1V4AA 4CBEA 2DI3A 3H2VA 3ZQYA 1Z5ZA 3ZVRA 3RW0A 3UMKA 1LS1A 1O87A 1VLSA 1ZHZA 3CZ6A 2P6VA 2BC5A 2XM4A 1NG1A 4N6HA 4KC9A 2R02A 4MVQA 4QI0A 4EMLA 4H54A 3Q7LA 3AG1C 3TQOA 2J0WA 1KU2A 3LS0A 1LKXA 3GEEA 5KYWA 2PFDA 4L6RA 3N24A 4IWBA 5F28E 2CCYA 2G3VA 4JCHA 5A6BA 3ADBA 3MFNA 3T88A 4CDVA 1FAPB 4W8PA 3PHF2 3OWTA 3SEOA 4BJ5A 4E18A 4O79A 5A69A 3QVZA 1MMGA 4CSAA 5A6KA 1KTMA 3RFYA 3U9JA 2KK1A 1WTYA 1Q0GA 2VB6A 4EIYA 3N0TA 1YYXA 4JTAB 4DBQA 3U0CA 1DCIA 1T6IA 2VC9A 3QMKA 2ETSA 4J30B 1DUBA 4MNDA 2R7OA 1N1CA 1JAFA 3S84A 4J7TA 2B0HA 4MVUA 2YZSA 2FAPB 3W2VA 3MYBA 1UX5A 5B3SC 1PD1A 1XWJA 2YWAA 2HMZA 3E9VA 2DYSC 3CAXA 4PFPA 1ZZPA 4J7YA 4I42A 1MNEA 3LS1A 4YN0B 3V5YA 3Q6MA 5COGA 4MVOA 4I1MA 1EY3A 3EGXA 5E33A 4FZWC 1Z6AA 1ZHWA 2Y3DA 1NFOA 4A4AA 1OKKD 3ASOC 3B0VC 3ZDLA 5A6JA 1LI7A 2WVOA 3ZTMA 3DJNB 1RKEA 1MMNA 4YL1A 1HMOA 4YK5A 2ZXOA 2KW3C 4F47A 2L9JA 3MYIA 4Q5SF 1HMDA 1TFKB 3VF0A 3V7OA 3K1HA 3EG9A 4GEHA 1C17M 1NU7D 1HZDA 5DQTA 3JSZA 3L34A 1OW7A 4NY3A 2XLVA 2C03A 2EPNA 3ADCA 4C3DA 1VK5A 2A6EF 4Q4ZF 2HV7A 3JSEO 1S05A 4HEAJ 1HE9A 4CJGA 4K3WA 1WOLA 3C8GA 1FFTC 1T6QA 4PJNA 4DXWA 1RJ9A 3X2QC 4W8KA 3DKAA 4G7OF 3R9SA 4U5HA 5E3CA 4IZDA 1M56C 4ULWA 3U5SA 2LK4A 2EIJC 4DBRA 4GYTA 3FOPA 2IXNA 2NPUA 3WAQA 2LFDA 5E3AA 3EFOB 4DRHB 3M1CB 1YVIA 3GWNA 4JFCA 2J8WA 2R7TA 1AEPA 3AG2C 3KYIA 4O6YA 2H7BA 3SXYA 4X0RA 3G4ZA 3B0UX 1BR4A 4DRJB 4JJFA 4EKWA 5K0IA 3QXZA 3B9QA 3SLLA 1F1MA 1OCRC 4JURI 1QZXA 2KJGA 3HNLA 2XL8A 4AX2A 3DMDA 3GEIA 4OG1A 4IZBA 1BR1A 4FX5A 1SZIA 2M4EA 2ASRA 4CJOA 5D92A 4JKVA 1YZCA 2R25A 2V3CC 1IW7F 2XLHA 3W8IB 2HSQA 4KBLA 1WZ8A 2NSGA 3IHUA 3Q6NA 3OC7A 4JW1A 3T8AA 1NLXA 4QDLA 2VASA 3C62A 2ZD9A 1ORYA 4CS9C 2P63A 4H4KC 2A1DD 3JTLO 1QVXA 4K0DA 4ER9A 3LNRA 1ZW2A 3W8HA 3GM1A 5TJ5E 2XS8A 4U9EA 3QZCA 3KH2A 4C3EA 4DOZA 5JVEA 4WGZA 4K2NA 1K04A 3C7JA 3ABLC 4JJGA 2R7XA 3AM1A 4JTCB 1XZQA 1EA8A 1EF9A 3V5XA 2G3KA 3T6BA 2YLGA 5EGYA 3HTKC 1Q0MA 4LDQA 3TULA 1Q0DA 1ZHTA 2HMQA 2IM8A 4JRZA 5B1AC 2A0BA 3SXKA 4NEKA 3NDBB 1Q0KA 3POVA 1A7EA 4IZCA 4N6CA 2CNWA 3ZSUA 2R03A 1O3UA 3T4RA 1M6TA 1TFOB 3NYJA 3MLGA 1O5HA 2KC3A 3V5ZA 4XQ1A 2O9XA 4AK9A 4OIPF 4MVRA 4PFOA 3ASNC 1VTMP 5L0FA 4QIIA 4DJ9A
chains in the Genus database with same CATH topology
3AJMA 1QVXA 3ADBA 3MFNA 3ADDA 3L8JA 3GM1A 1PV3A 1K05A 2L6GA 2HSBA 4XEFA 3BRJA 3C8GD 3W8HB 1UX4A 1K40A 1K04A 3O4XE 3GM3A 3B71A 3AM1A 4NQFA 2L6HA 1KNYA 4NNQA 1KTMA 4EBJA 1Y64B 2KK1A 1WTYA 1OW7A 2JPUA 3C18A 3TULA 1V4AA 3U0CA 3A4MA 4GEHB 3ADCA 3O10A 3L8IA 1OW8A 3JZ0A 1WWPA 3JYYA 1WOLA 3C8GA 2JX0A 2L6FA 3K7DA 2PBEA 4EBKA 3S9OA 1UX5A 3IRBA 1O3UA 3C8GB 3RQFA 4XEVA 2YWAA 3A4NA 3RQEA 4R32A 2Q00A 1ZZPA 3W8IB 3RQGA 1RJMA 2LK4A 1JOGA 1OW6A 5F28E 2P63A 4XEKA 3GM2A 3A4LA 3U3FA 1UFBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WWP A;  3JYY A;  2Q00 A;  3AJM A;  1QVX A;  1KNY A;  1WOL A;  3W8I B;  3MFN A;  1KTM A;  3C8G A;  2JX0 A;  4EBJ A;  4R32 A;  2L6F A;  2KK1 A;  3K7D A;  3L8J A;  2PBE A;  3RQG A;  1WTY A;  3S9O A;  4EBK A;  3GM1 A;  2LK4 A;  1JOG A;  1OW7 A;  2JPU A;  1PV3 A;  1OW6 A;  3C18 A;  4NQF A;  3TUL A;  1V4A A;  1O3U A;  1K05 A;  3U0C A;  2L6G A;  3C8G B;  3RQF A;  4GEH B;  2HSB A;  4XEF A;  3BRJ A;  3C8G D;  3W8H B;  5F28 E;  3O10 A;  1K40 A;  3L8I A;  1K04 A;  1OW8 A;  3GM2 A;  4XEV A;  2YWA A;  3GM3 A;  4XEK A;  3JZ0 A;  3RQE A;  3U3F A;  3B71 A;  1UFB A;  1ZZP A;  2L6H A; 
#chains in the Genus database with same CATH topology
 4E0I A;  4WJ0 A;  4AE4 B;  3GEH A;  2NSF A;  2J9W A;  3FMS A;  3TOM A;  1OXK A;  1ZU4 A;  5BQI A;  3OA1 A;  5JT4 A;  2RSE B;  5FCL A;  2LCH A;  4NCQ A;  3ZTZ A;  4M63 A;  1UX4 A;  2BE5 F;  4LLC A;  1YA7 O;  3B29 A;  1NSG B;  3T89 A;  1NBB A;  1Y64 B;  4OIO F;  4GQH A;  3WG7 C;  2WZL A;  3KMI A;  2ICW G;  2TMV P;  1GS9 A;  3A4M A;  2VCC A;  3KL4 A;  2R7R A;  1U89 A;  1MMD A;  3JZ0 A;  2R7W A;  3IQC A;  2NUT B;  4CIP A;  2PBE A;  4E0H A;  1T5O A;  2R7Q A;  1HY5 A;  4P9T A;  2W4B A;  2Y69 C;  1YA9 A;  1T9K A;  2ZXW C;  2Q00 A;  4XPY A;  3MOY A;  5AC4 A;  3IQ5 A;  2MHR A;  4O6M A;  2GFH A;  4ULV A;  3LJB A;  1LS4 A;  4JCS A;  2PP4 A;  2ZQR A;  3JT1 A;  3LLI A;  1OR2 A;  4U5E E;  3SNH A;  4JZA A;  3HNK A;  3DAG A;  2HJ3 A;  3K1I A;  2OKU A;  4IRU A;  3B0P A;  2YL0 A;  3NRH A;  3NMI A;  1M2V A;  3A9C A;  4ONS A;  3H65 A;  2A6H F;  1OR3 A;  2HKV A;  3IQT A;  2GA0 A;  3OEO A;  1K40 A;  2Q9B A;  5F5F A;  4PK4 A;  2NUP A;  2VX2 A;  1KNY A;  1W2W A;  4G7Z F;  3EHN A;  3HNI A;  1YAU O;  2J7P D;  4C3B A;  3HKK A;  2IOQ A;  2ZXR A;  2Q7R A;  3CSK A;  1JRA A;  1JPN A;  2J0X A;  3L1M A;  2QY9 A;  4XWJ A;  4U5C E;  2WZF A;  1QSP A;  3JYY A;  1NZY A;  3NKD A;  3G4X A;  1A41 A;  4LER A;  3FDU A;  2OG2 A;  5DS5 A;  3K7D A;  5KYX B;  2H7O A;  1G4U S;  3ZIB A;  5CI9 A;  1TWH A;  3DWW A;  3CEX A;  3VRC A;  3TOL A;  3T6G B;  3K33 A;  3O55 A;  3DAF A;  4YL0 A;  4AL1 A;  3N2Z B;  2H8A A;  1QPU A;  1M2O A;  4UDV A;  4ZLC A;  1OCC C;  1D0Z A;  1J8M F;  1SMY F;  2ZQQ A;  3L0I A;  2UUH A;  1RMV A;  5KJP A;  2Q3T A;  1I5N A;  1D1A A;  3AQC A;  3PDM P;  1E86 A;  3US6 A;  5D91 A;  2UZF A;  2L7A A;  3FOO A;  1E2X A;  3M79 A;  4BJ5 C;  1CPQ A;  2WB7 A;  4FWV A;  2D4U A;  4OIN F;  4KNV A;  1Q52 A;  3E70 C;  5AC5 A;  4U9D A;  1YLM A;  5KYY A;  2XL6 A;  2XXA A;  1D0X A;  4CSA C;  4O7G A;  1D1C A;  4BG0 A;  1BBH A;  4C7O B;  3SXZ A;  3ZWI A;  2OQM A;  5JS5 A;  3K6B A;  1V74 B;  5L0G A;  2F22 A;  1TWG A;  3TJ6 A;  1QQ3 A;  4OD5 A;  1YDI A;  2FGY A;  4NC3 A;  1GQA A;  4JOT A;  3LES A;  3KYJ A;  4CIH A;  2Z15 A;  1VYK A;  2VCA A;  1TKN A;  3BEH A;  2YL7 A;  4LDK A;  3EGD A;  2MWQ A;  5FZT A;  5A6B D;  1ZYR F;  4NTB A;  1A0B A;  3WOD F;  3HRX A;  1Q0F A;  2VRE A;  2AWC A;  2YLI A;  4ANJ A;  3FAP B;  3R9T A;  4BJ6 A;  1Y6D A;  2IXO A;  5JRA A;  3DE8 A;  5KYW B;  2EIK C;  1ZW3 A;  4N06 A;  1T6U A;  4YWQ A;  5COM A;  3F47 A;  3TD7 A;  4NTA A;  256B A;  2DYR C;  2XSE A;  3MX3 A;  3BRJ A;  3S27 A;  3GM3 A;  2PNO A;  3EPV A;  1E83 A;  3IEE A;  1OQC A;  2XLW A;  1YJG A;  1ZU5 A;  3SXM A;  4ZLD A;  2WVQ A;  1CPR A;  4YT4 A;  3U2L A;  3O10 A;  3KPH A;  3LAY A;  4K7B A;  4WGY A;  3TK0 A;  3G50 A;  5BQG A;  1Z23 A;  3O39 A;  3U3B A;  4CX9 A;  3LNM B;  5L0D A;  1LI5 A;  3FAJ A;  3S29 A;  4MVS A;  1MND A;  2OOC A;  4XTK A;  3H02 A;  5JSL A;  1OCZ C;  4E7S A;  5JLI A;  2MYS A;  1UIY A;  3SP1 A;  1LE2 A;  3DXJ F;  2RD9 A;  4U5G A;  2P0N A;  3M4C A;  2GWW A;  1Y4C A;  1RJM A;  5JBX A;  2J9V A;  4MQ9 F;  3T6J A;  5DVW A;  4DVZ A;  2KNH A;  2OJQ A;  3SZR A;  1PCX A;  3A4L A;  4MW3 A;  3EGX B;  4CS8 A;  2OCC C;  2OEX A;  3JRT A;  2PBP A;  1GM5 A;  3IQ6 A;  2YEV A;  2NG1 A;  5F5H A;  1HE1 A;  1ORJ A;  1XZP A;  2JD3 A;  2Y3B A;  1LE4 A;  1H6G A;  2OJE D;  3F46 A;  4MTO A;  4XEF A;  3C8G D;  1RKE B;  3NMJ A;  2OU6 A;  1YYJ A;  3O4X E;  2Y3G A;  3GAN A;  2L6H A;  1B68 A;  3VYW A;  1S7Z A;  1RCP A;  4EBB A;  2KQ9 A;  4RBN A;  3LLK A;  3T9O A;  3DZA A;  4JVS A;  3S90 A;  4GEH B;  2G62 A;  2LD6 A;  2Y3H A;  4PJL A;  3U2M A;  2X0C A;  1E84 A;  4OIR F;  2P7V A;  4NTF A;  3DM5 A;  4P6I C;  2YLD A;  4JEA A;  3HIN A;  2V26 A;  2XLO A;  3AQB A;  3JCU Q;  1Z63 A;  3C8G B;  1FTS A;  1RJ9 B;  2XLE A;  3I47 A;  3IPM O;  1ST6 A;  4I4Z A;  2C04 A;  3RQG A;  4YJW A;  2XM0 A;  5COF A;  1Z7Q c;  2LQG A;  1TWC A;  3FVY A;  1VMA A;  2XLM A;  5IY5 C;  3ABM C;  3AOU A;  5T3W A;  4PAC A;  2UUI A;  3MYF A;  3DI5 A;  2YHS A;  1K05 A;  3UMI A;  2I8B A;  4OIQ F;  5KYX A;  2J46 A;  3NYM A;  2R7V A;  1V55 C;  2HJM A;  2A68 F;  2AWY A;  4YL3 A;  4JCZ A;  2R9R B;  4WCZ A;  1T01 A;  3AGT A;  1GGQ A;  1OW8 A;  3PZK A;  1FMW A;  1RXQ A;  3K66 A;  4G7H F;  1WN0 A;  2L6F A;  4EBK A;  3QVY A;  2H7V C;  2GTR A;  2CDQ A;  3KKB A;  2QQ3 A;  3GOR A;  2BL2 A;  1HW2 A;  1WAS A;  3RQE A;  4BJT A;  3RYL A;  4G78 A;  3ATP A;  4JWV A;  1NZE A;  2EJ5 A;  5L0H A;  2YL1 A;  3Q1T A;  2KSF A;  1JOG A;  1OXB A;  1OW6 A;  2LSE A;  3A11 A;  4IAQ A;  2P1A A;  5DS4 A;  4WAB A;  2WL8 A;  3U3F A;  2J9B A;  4MTG A;  4PR9 A;  1QKR A;  3PCV A;  3VAY A;  3L8J A;  4I44 A;  1FFH A;  3UGP A;  1JMW A;  1ORS C;  1PV3 A;  2EIN C;  3VM6 A;  1C02 A;  2L6G A;  4A2N B;  2ZPA A;  3W8H B;  2HV6 A;  2A0U A;  4QIJ A;  1J8Y F;  2CNW D;  4I3M A;  1OKK A;  1FR0 A;  4CDY A;  3JRM O;  4Z9I A;  5GPG B;  5C9G A;  5T1D B;  3WHN A;  1R4T A;  2LIG A;  4KNW A;  2YKZ A;  3J06 A;  3Q0G A;  1WGW A;  1CGO A;  4EWC A;  2R05 A;  2JX0 A;  4P9F A;  4N4W A;  4D4N A;  3FXH A;  5DLJ A;  4I52 A;  4RD9 A;  3FDQ A;  4ELW A;  4BEJ A;  1CGM E;  3SYN A;  2R7S A;  3P5M A;  4MVM A;  3G64 A;  1ZHX A;  2A69 F;  3S0X A;  2KYH A;  3EFO A;  2Q4F A;  3U8V A;  3JYH A;  4FZW A;  1EI7 A;  2AVK A;  1IZM A;  2HUJ A;  4PJJ A;  4FAP B;  1NU9 C;  3K1I C;  5KYN A;  1UFB A;  1LIH A;  1C03 A;  1JXZ A;  5L0I A;  4I1O B;  2X51 A;  4BJ1 A;  3EHM A;  1FNT c;  3EJN A;  2QLA A;  2B0J A;  1RJN A;  4CDA A;  1JPJ A;  5BUO A;  5L0C A;  3I5Q A;  1LVK A;  3ITF A;  1M57 C;  1MQV A;  2KGO A;  1TQG A;  3Q0J A;  3UR3 C;  1MMA A;  5L3Q A;  3C18 A;  2JPU A;  1L3P A;  4B6I A;  2LP4 A;  4CS7 A;  4MI2 A;  3L8I A;  5DQZ A;  1WWP A;  2HZ8 A;  3HLZ A;  1BZ4 A;  1A7D A;  1G8X A;  1NFN A;  4YT2 A;  1QLE C;  4JC7 A;  1EQ1 A;  2WZG A;  5KYU B;  2XL4 A;  1VYI A;  2QNL A;  3IRB A;  3W8I A;  4U1A A;  3RQF A;  3ABK C;  2IXP A;  3A4N A;  1H9T A;  1FMV A;  4LDR A;  4JE9 A;  4J32 B;  2D5R B;  2HW5 A;  4ZU2 A;  3U8P A;  3RSI A;  3R7C A;  3RKO F;  2W4M A;  2XLD A;  5JP7 A;  4XPW A;  2YRF A;  1UG7 A;  3DJU B;  4MS2 A;  4OD4 A;  2Q9C A;  1PD0 A;  2IEX A;  3W2W A;  4K1O A;  4IJJ A;  2L81 A;  1E85 A;  4G0H A;  3KQF A;  3C63 A;  3H81 A;  2WVN A;  4AL0 A;  1M2V B;  3DE9 A;  5T3T A;  2EPL X;  2HSB A;  1R5I D;  5AGF A;  5B3I A;  4NQF A;  2IBF A;  3S28 A;  4U5F E;  3LUT B;  2XS1 A;  1U6H A;  2AP3 A;  1VB5 A;  3AG3 C;  2NUP B;  4FES A;  3R0O A;  3RVY A;  5HV9 A;  2VCB A;  1I4Y A;  4XPX A;  3AG4 C;  4U5D E;  4DRI B;  5BQH A;  3EZI A;  5JUA A;  2CGE A;  3MBG A;  2P61 A;  2FBM A;  3H2U A;  4JIO A;  4Z9H A;  1Z3I X;  3RVZ A;  1NZY B;  1AUE A;  2HS5 A;  2IXM A;  5EK0 A;  2PX3 A;  3W4Y A;  1WAT A;  2YQY A;  5E2Q A;  2ZXP A;  3RIP A;  2F6Q A;  2EPO A;  1YZA A;  3QW1 A;  1A7V A;  3UGO A;  4BPM A;  2CW0 F;  4AE4 A;  3M15 A;  1LPE A;  4CS9 A;  4JYL A;  4U19 A;  1TR2 A;  3GM2 A;  4BJ6 C;  3AJM A;  2Q9A A;  3EZH A;  1ZHY A;  2EPM X;  3UNG C;  2I15 A;  2OEV A;  3EQL F;  4IAO A;  4E17 A;  3DD7 A;  5EHH A;  5HSW A;  5L3V A;  1SF8 A;  1EKY A;  2W45 A;  2XRH A;  4E7Z A;  5A6A A;  4OLQ A;  1VLT A;  2FFH A;  1CGN A;  3B71 A;  1SYQ A;  3TRR A;  1DOW A;  3LEV A;  4MOU A;  4O6N A;  2LFF A;  4RDA A;  5KYY B;  2NUT A;  2XXA B;  1HW1 A;  1D0Y A;  1AVO B;  2YL3 A;  1U0B B;  1D1B A;  3HJC A;  4QI2 A;  3QTH A;  2EIM C;  1LM3 B;  2VH3 A;  2DGJ A;  3RH3 A;  4Q7C A;  4HFK B;  4MTF A;  3QW0 A;  3FHD A;  3U9M A;  2R7U A;  1VOM A;  5L0J A;  5CI8 A;  4EHP A;  3EG9 B;  2FW2 A;  1BDJ B;  4XLP F;  4PJM A;  3SWX A;  4XEV A;  1V54 C;  3EGD B;  5JBW A;  2W9Y A;  2GAQ A;  4JEB A;  4FJW D;  3I4U A;  5DS6 A;  1BR2 A;  2DUB A;  5B1B C;  2AU5 A;  3NMK A;  3ECS A;  3LEO A;  2J9U A;  4DVY P;  1RKC A;  3R2P A;  2EIL C;  1G4W R;  4JTD B;  4CS8 C;  2QE9 A;  3ADD A;  3DM9 B;  2YVK A;  3Q7G A;  2GDC A;  3QK8 A;  2E87 A;  3ZC4 A;  4IGG A;  4ELS A;  3NKE A;  2M64 A;  3TJ5 A;  4EUK B;  3TLF A;  1JR8 A;  2IYL D;  1H7I A;  4NNQ A;  2DB4 A;  3EH1 A;  3X1O A;  4EBJ A;  3EH2 A;  4YT5 A;  4BEM J;  1ZVZ A;  3NG1 A;  1MJ3 A;  2QUP A;  3AGU A;  1G5Z A;  2PX0 A;  4U5B E;  4KI2 A;  1EF8 A;  1SR2 A;  3C8Z A;  4IB4 A;  3S9O A;  1OCO C;  4KNP A;  4F4B A;  3QXI A;  2CYD A;  2PF4 E;  2J7P A;  4IAR A;  1YAR O;  3CQZ A;  2QTV A;  1TWA A;  4HE8 D;  4R32 A;  3M4B A;  2J45 A;  4D4X A;  4MVZ A;  4HFF B;  4YT8 A;  2Y39 A;  3I5P A;  3PMR A;  4LAC B;  4XEK A;  4ELX A;  3NYL A;  2EPK X;  3HNJ A;  3ZG1 A;  5CIV A;  2PPY A;  2HFI A;  4MW8 A;  3GOD A;  3GWL A;  4Z9J A;  4U18 A;  3ZQV A;  3UMH A;  4C7O A;  4XLN F;  5KYU A;  1Q51 A;  1L7C A;  1APC A;  1H9G A;  3O6X A;  1I4Z A;  4LLE A;  3RF3 A;  1DOV A;  1V4A A;  4CBE A;  2DI3 A;  3H2V A;  3ZQY A;  1Z5Z A;  3ZVR A;  3RW0 A;  3UMK A;  1LS1 A;  1O87 A;  1VLS A;  1ZHZ A;  3CZ6 A;  2P6V A;  2BC5 A;  2XM4 A;  1NG1 A;  4N6H A;  4KC9 A;  2R02 A;  4MVQ A;  4QI0 A;  4EML A;  4H54 A;  3Q7L A;  3AG1 C;  3TQO A;  2J0W A;  1KU2 A;  3LS0 A;  1LKX A;  3GEE A;  5KYW A;  2PFD A;  4L6R A;  3N24 A;  4IWB A;  5F28 E;  2CCY A;  2G3V A;  4JCH A;  5A6B A;  3ADB A;  3MFN A;  3T88 A;  4CDV A;  1FAP B;  4W8P A;  3PHF 2;  3OWT A;  3SEO A;  4BJ5 A;  4E18 A;  4O79 A;  5A69 A;  3QVZ A;  1MMG A;  4CSA A;  5A6K A;  1KTM A;  3RFY A;  3U9J A;  2KK1 A;  1WTY A;  1Q0G A;  2VB6 A;  4EIY A;  3N0T A;  1YYX A;  4JTA B;  4DBQ A;  3U0C A;  1DCI A;  1T6I A;  2VC9 A;  3QMK A;  2ETS A;  4J30 B;  1DUB A;  4MND A;  2R7O A;  1N1C A;  1JAF A;  3S84 A;  4J7T A;  2B0H A;  4MVU A;  2YZS A;  2FAP B;  3W2V A;  3MYB A;  1UX5 A;  5B3S C;  1PD1 A;  1XWJ A;  2YWA A;  2HMZ A;  3E9V A;  2DYS C;  3CAX A;  4PFP A;  1ZZP A;  4J7Y A;  4I42 A;  1MNE A;  3LS1 A;  4YN0 B;  3V5Y A;  3Q6M A;  5COG A;  4MVO A;  4I1M A;  1EY3 A;  3EGX A;  5E33 A;  4FZW C;  1Z6A A;  1ZHW A;  2Y3D A;  1NFO A;  4A4A A;  1OKK D;  3ASO C;  3B0V C;  3ZDL A;  5A6J A;  1LI7 A;  2WVO A;  3ZTM A;  3DJN B;  1RKE A;  1MMN A;  4YL1 A;  1HMO A;  4YK5 A;  2ZXO A;  2KW3 C;  4F47 A;  2L9J A;  3MYI A;  4Q5S F;  1HMD A;  1TFK B;  3VF0 A;  3V7O A;  3K1H A;  3EG9 A;  4GEH A;  1C17 M;  1NU7 D;  1HZD A;  5DQT A;  3JSZ A;  3L34 A;  1OW7 A;  4NY3 A;  2XLV A;  2C03 A;  2EPN A;  3ADC A;  4C3D A;  1VK5 A;  2A6E F;  4Q4Z F;  2HV7 A;  3JSE O;  1S05 A;  4HEA J;  1HE9 A;  4CJG A;  4K3W A;  1WOL A;  3C8G A;  1FFT C;  1T6Q A;  4PJN A;  4DXW A;  1RJ9 A;  3X2Q C;  4W8K A;  3DKA A;  4G7O F;  3R9S A;  4U5H A;  5E3C A;  4IZD A;  1M56 C;  4ULW A;  3U5S A;  2LK4 A;  2EIJ C;  4DBR A;  4GYT A;  3FOP A;  2IXN A;  2NPU A;  3WAQ A;  2LFD A;  5E3A A;  3EFO B;  4DRH B;  3M1C B;  1YVI A;  3GWN A;  4JFC A;  2J8W A;  2R7T A;  1AEP A;  3AG2 C;  3KYI A;  4O6Y A;  2H7B A;  3SXY A;  4X0R A;  3G4Z A;  3B0U X;  1BR4 A;  4DRJ B;  4JJF A;  4EKW A;  5K0I A;  3QXZ A;  3B9Q A;  3SLL A;  1F1M A;  1OCR C;  4JUR I;  1QZX A;  2KJG A;  3HNL A;  2XL8 A;  4AX2 A;  3DMD A;  3GEI A;  4OG1 A;  4IZB A;  1BR1 A;  4FX5 A;  1SZI A;  2M4E A;  2ASR A;  4CJO A;  5D92 A;  4JKV A;  1YZC A;  2R25 A;  2V3C C;  1IW7 F;  2XLH A;  3W8I B;  2HSQ A;  4KBL A;  1WZ8 A;  2NSG A;  3IHU A;  3Q6N A;  3OC7 A;  4JW1 A;  3T8A A;  1NLX A;  4QDL A;  2VAS A;  3C62 A;  2ZD9 A;  1ORY A;  4CS9 C;  2P63 A;  4H4K C;  2A1D D;  3JTL O;  1QVX A;  4K0D A;  4ER9 A;  3LNR A;  1ZW2 A;  3W8H A;  3GM1 A;  5TJ5 E;  2XS8 A;  4U9E A;  3QZC A;  3KH2 A;  4C3E A;  4DOZ A;  5JVE A;  4WGZ A;  4K2N A;  1K04 A;  3C7J A;  3ABL C;  4JJG A;  2R7X A;  3AM1 A;  4JTC B;  1XZQ A;  1EA8 A;  1EF9 A;  3V5X A;  2G3K A;  3T6B A;  2YLG A;  5EGY A;  3HTK C;  1Q0M A;  4LDQ A;  3TUL A;  1Q0D A;  1ZHT A;  2HMQ A;  2IM8 A;  4JRZ A;  5B1A C;  2A0B A;  3SXK A;  4NEK A;  3NDB B;  1Q0K A;  3POV A;  1A7E A;  4IZC A;  4N6C A;  2CNW A;  3ZSU A;  2R03 A;  1O3U A;  3T4R A;  1M6T A;  1TFO B;  3NYJ A;  3MLG A;  1O5H A;  2KC3 A;  3V5Z A;  4XQ1 A;  2O9X A;  4AK9 A;  4OIP F;  4MVR A;  4PFO A;  3ASN C;  1VTM P;  5L0F A;  4QII A;  4DJ9 A; 
#chains in the Genus database with same CATH homology
 3AJM A;  1QVX A;  3ADB A;  3MFN A;  3ADD A;  3L8J A;  3GM1 A;  1PV3 A;  1K05 A;  2L6G A;  2HSB A;  4XEF A;  3BRJ A;  3C8G D;  3W8H B;  1UX4 A;  1K40 A;  1K04 A;  3O4X E;  3GM3 A;  3B71 A;  3AM1 A;  4NQF A;  2L6H A;  1KNY A;  4NNQ A;  1KTM A;  4EBJ A;  1Y64 B;  2KK1 A;  1WTY A;  1OW7 A;  2JPU A;  3C18 A;  3TUL A;  1V4A A;  3U0C A;  3A4M A;  4GEH B;  3ADC A;  3O10 A;  3L8I A;  1OW8 A;  3JZ0 A;  1WWP A;  3JYY A;  1WOL A;  3C8G A;  2JX0 A;  2L6F A;  3K7D A;  2PBE A;  4EBK A;  3S9O A;  1UX5 A;  3IRB A;  1O3U A;  3C8G B;  3RQF A;  4XEV A;  2YWA A;  3A4N A;  3RQE A;  4R32 A;  2Q00 A;  1ZZP A;  3W8I B;  3RQG A;  1RJM A;  2LK4 A;  1JOG A;  1OW6 A;  5F28 E;  2P63 A;  4XEK A;  3GM2 A;  3A4L A;  3U3F A;  1UFB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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