3L8JA

Crystal structure of ccm3, a cerebral cavernous malformation protein critical for vascular integrity
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
200
structure length
200
Chain Sequence
XXXTTSMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFVSANRLIHQTNLILQTFKT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Programmed cell death protein 10
total genus 75
structure length 200
sequence length 200
ec nomenclature
pdb deposition date 2009-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06840 DUF1241 Protein of unknown function (DUF1241)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 3l8jA01
1.20.120.330 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Nucleotidyltransferases domain 2 3l8jA02
3W8HB 4XEVA 3K7DA 2YWAA 1V4AA 3C18A 3RQGA 2KK1A 3BRJA 2L6GA 2PBEA 1WTYA 3U3FA 2JPUA 1PV3A 2HSBA 1WWPA 4NQFA 2LK4A 3GM3A 1KTMA 5F28E 1K40A 3B71A 1K05A 2Q00A 3GM2A 3O10A 4XEFA 3U0CA 3C8GB 3L8JA 3S9OA 1KNYA 3JYYA 4R32A 1QVXA 3L8IA 2JX0A 1JOGA 3RQFA 3C8GD 1OW8A 1UFBA 1ZZPA 3GM1A 3JZ0A 4EBJA 3TULA 1K04A 2L6FA 2L6HA 1O3UA 1WOLA 4GEHB 4XEKA 1OW6A 3AJMA 1OW7A 3MFNA 3RQEA 3W8IB 3C8GA 4EBKA
chains in the Genus database with same CATH superfamily
2YKZA 3V7OA 4BJ6C 3F46A 3QVYA 5E33A 5JSLA 4AE4B 3L8JA 3SNHA 1V54C 4JW1A 3TOMA 1YYJA 4RBNA 3C62A 2RSEB 4PJNA 2YHSA 2Y39A 1RJ9A 5K0IA 2W45A 4JIOA 1WWPA 3ABLC 1Q0KA 3NDBB 1TWHA 3ECSA 2GDCA 5DS5A 4FZWA 4CS9A 2TMVP 1MMGA 3FDUA 4EWCA 1E85A 1VOMA 5AGFA 4NY3A 4DVZA 4JZAA 3SXMA 3ABKC 4A4AA 2EPMX 4AL1A 3RFYA 1KNYA 2L81A 4I42A 4DBQA 5KYWA 2DYSC 4JJFA 3S90A 3DAFA 4ULVA 1NZEA 1ZU5A 3ATPA 3TQOA 2G3VA 3A4NA 1SZIA 3NRHA 1FTSA 5T1DB 1ORJA 4PR9A 1YJGA 5L0CA 5JBWA 3RYLA 3L1MA 3M1CB 3L0IA 3U8VA 1NBBA 1VYIA 2EPLX 3ASNC 2OCCC 4RDAA 1FAPB 5COGA 3ZQYA 2R7XA 2Q9CA 2L6FA 2YL1A 2OOCA 2AWYA 2FFHA 4LDQA 4MVQA 4BPMA 1CGOA 3UMIA 3E9VA 4U5HA 2CDQA 2J8WA 4U18A 1WOLA 2PX0A 3KQFA 5B1AC 2IBFA 4MW3A 4I4ZA 2CGEA 3SXZA 3LLIA 2Q7RA 3KPHA 3QTHA 2LK4A 1OKKA 4JC7A 2B0HA 1C03A 3B0PA 2J46A 3W2VA 3OC7A 4PJJA 2B0JA 1PV3A 4U19A 2XLDA 3CSKA 3DE9A 2HZ8A 1VK5A 1AVOB 1UX4A 2YVKA 3X1OA 4DRIB 2FAPB 1LPEA 1T6QA 4MVRA 1RKEB 1CGME 2W4MA 3IPMO 2JD3A 5JT4A 3EPVA 2XRHA 1EF9A 2H7VC 2R7UA 3VRCA 1FNTc 5JRAA 3L34A 4XEKA 4PK4A 1A7DA 3DWWA 1OQCA 1V4AA 2XLEA 5JUAA 1C02A 2LFFA 3KYIA 3A9CA 2J9WA 1TFKB 4GQHA 3DJNB 3PDMP 2NUPB 4EHPA 4G7ZF 2YL0A 4ONSA 2P1AA 1O3UA 3FAJA 1MNEA 2VCAA 4G0HA 4IJJA 1NFOA 3ITFA 1TR2A 2CNWA 1H6GA 4NQFA 1OR3A 2P7VA 4OG1A 3QW0A 4AX2A 1VB5A 1APCA 4N6CA 3K7DA 3N0TA 1DOVA 1I4ZA 2OJQA 4BJ5A 3LAYA 3QMKA 2P0NA 4B6IA 4C7OB 1BDJB 4I44A 3GEEA 1NFNA 4YL0A 2YEVA 2H7OA 2GFHA 4FWVA 2HS5A 4IGGA 4U5CE 3LS1A 1Q0FA 3HNKA 4DBRA 4N6HA 1TFOB 3EZIA 3V5ZA 1WN0A 3U5SA 3M15A 1E86A 256BA 3R7CA 1O87A 2OEVA 3IQTA 3A4LA 3JZ0A 4CDAA 1K04A 3QK8A 1YARO 4MVZA 2R7QA 3N2ZB 1OCOC 3RQGA 3P5MA 2C03A 3ABMC 1HZDA 4L6RA 2QY9A 3EHNA 2GTRA 4DVYP 3K1HA 3ADCA 4JTAB 4C3EA 5TJ5E 1KU2A 5JLIA 2XL8A 4C7OA 5JVEA 4OIRF 4XPYA 3K6BA 1KTMA 1EKYA 3EQLF 1FMVA 1E84A 3SEOA 2CCYA 1OCCC 1S7ZA 3B29A 4YL3A 3T6BA 3PCVA 2J0WA 1Y64B 3A11A 3MYIA 3V5XA 2NUTB 5L0JA 2XLOA 3G4XA 3AM1A 5DQTA 2E87A 1D0XA 2XM0A 2HV6A 3ADDA 1M56C 2OG2A 4ULWA 3C8GA 2R7VA 3T9OA 2R02A 2M64A 4EIYA 2HV7A 2M4EA 2KC3A 1H7IA 1W2WA 2Q9AA 2R7SA 3NG1A 4E0IA 4LLEA 1XWJA 5CI9A 2R7OA 5CIVA 1Z23A 4GYTA 1LVKA 4XPXA 4BG0A 2HKVA 1NZYA 5L0FA 5KYYB 2LFDA 2A0UA 4AL0A 4I1MA 4MTGA 3MX3A 3UMKA 2KK1A 3VAYA 1RKCA 3TD7A 2VCCA 3T6JA 4HEAJ 4J30B 2W4BA 1SMYF 4BJTA 4G7OF 1YZAA 5CI8A 3TULA 4K7BA 4F47A 3CEXA 3AG2C 1MJ3A 1Q52A 3IQ6A 4U5EE 3TOLA 2YLGA 4NC3A 4JKVA 3US6A 4G78A 5D91A 1DCIA 3Q6MA 1RJ9B 2H7BA 2IYLD 4U9DA 3LUTB 3R9SA 1ZW3A 2AWCA 1SYQA 1JAFA 1YA9A 2J0XA 2HSQA 1D0ZA 2KYHA 5KYYA 4H4KC 2R05A 1OKKD 2CYDA 5A6BD 3GM3A 1O5HA 3I5PA 3NMJA 1DUBA 4CDYA 3ZQVA 2IXNA 2L9JA 3T8AA 4OD4A 4BJ1A 1D0YA 2AP3A 4JRZA 1GM5A 5KYWB 1OXBA 2GAQA 3CQZA 2ZQRA 1MNDA 2PFDA 1AUEA 4I3MA 1RJMA 1HY5A 1M2OA 5HSWA 1GGQA 1QZXA 1PD0A 3SXKA 2PP4A 4XLNF 2ZD9A 4E0HA 3AGTA 3GODA 4CS7A 5KYXA 2XLWA 3FHDA 4MVOA 4EBBA 4E7SA 2IXOA 2A68F 3N24A 1OW7A 4FESA 2H8AA 3HTKC 4FZWC 1A0BA 5KYUA 4CS9C 5BQHA 1J8YF 3K66A 4ZLDA 2V26A 1Y4CA 2Q00A 3DZAA 3L8IA 1T6UA 3QW1A 1FFHA 2LSEA 4JCHA 1B68A 1IW7F 4NNQA 2J7PD 2CNWD 2VREA 4IZCA 4NCQA 1M2VA 1VYKA 5B1BC 2IEXA 3LNMB 2WVOA 5BQIA 4DXWA 3QXIA 2XS1A 4CDVA 4K1OA 1LIHA 1ZHWA 3SLLA 1M57C 2VASA 4MNDA 2OEXA 2W9YA 2PNOA 3AG3C 4O6MA 5EHHA 5FCLA 1JPJA 4JEBA 1YA7O 3GEHA 3LJBA 1ZHXA 2LP4A 1ZHTA 4N4WA 3F47A 4JURI 1CPRA 4AK9A 5DS6A 1LE4A 1OW6A 2Y3DA 3H65A 3FDQA 2L6GA 2YZSA 5L3VA 3EZHA 1FR0A 1ZW2A 1XZPA 2HJMA 3V5YA 2XS8A 2P6VA 1YZCA 3PMRA 2BE5F 3DXJF 3SYNA 1NLXA 2UUIA 1G4WR 5DLJA 3Q0GA 2ASRA 3U9MA 1QPUA 5A6BA 4C3BA 2OQMA 2EJ5A 4YT2A 5E3AA 4LACB 3HNIA 1LKXA 1PCXA 2FW2A 3Q1TA 3A4MA 2WVQA 4OLQA 4QI2A 4LDKA 1G5ZA 3U0CA 2HUJA 4ELWA 3JSZA 1E83A 2ZXWC 4JTCB 1OW8A 2A1DD 1VLTA 4JVSA 4NTFA 3RVZA 3KYJA 2EPOA 3TRRA 1OCZC 3HNLA 4HFFB 3LLKA 3ZIBA 4C3DA 5KJPA 2A69F 4ER9A 3C8GD 2HW5A 4NTAA 2AVKA 3EGDB 2DGJA 1QQ3A 4OINF 4YK5A 1I4YA 4HE8D 2YLIA 2LD6A 3M4CA 3RKOF 1E2XA 2F22A 5JP7A 2OKUA 3UMHA 5B3SC 2QUPA 1BR4A 2P61A 4U5BE 2J7PA 2R9RB 4Z9HA 1LM3B 3W8HA 4JFCA 4I1OB 4MVSA 3Q7GA 3UGOA 2PF4E 4EBJA 3AJMA 2R25A 3TJ5A 2VX2A 1HMOA 1U6HA 1U89A 3EGXA 4P9TA 2X0CA 2R7RA 1R4TA 3MYFA 1EF8A 1S05A 3Q7LA 3B0VC 3C7JA 4BJ5C 3HJCA 3EFOB 3EGDA 1JRAA 1YYXA 1UIYA 4DJ9A 4DRHB 2OJED 1RMVA 4XLPF 3CAXA 3DE8A 2WZFA 4MTOA 4XEFA 1XZQA 3WHNA 1FMWA 4WGYA 2VB6A 4W8KA 4JCZA 1ZZPA 4BEMJ 1Y6DA 4IAQA 4FJWD 2YL3A 4PFPA 4U1AA 3O6XA 4K3WA 3GEIA 2FGYA 3AG1C 4J7TA 1K40A 2P63A 2YLDA 3C8GB 2XL4A 4PJMA 4E18A 1NSGB 4U5GA 3O55A 3H81A 1Z5ZA 3QZCA 4EKWA 2Y3BA 2PBEA 2BL2A 3EFOA 1MMAA 1MMDA 3K1IA 4QDLA 3FOPA 3EJNA 3UR3C 1NZYB 4LLCA 4KC9A 1AEPA 2C04A 4XTKA 4CSAA 1C17M 3M4BA 5A6JA 3RQFA 4XQ1A 1A7EA 3ZVRA 3OEOA 1H9TA 5COFA 2WVNA 3W4YA 5COMA 3S27A 2FBMA 2WB7A 3ADBA 3DJUB 3JCUQ 3RH3A 3JYYA 4MTFA 3MYBA 3ZSUA 2Y3HA 3U2MA 3C63A 4U5FE 4I52A 2IOQA 4CS8A 3JSEO 2YRFA 2DUBA 3TLFA 2YWAA 1HW1A 4K0DA 3B0UX 3G64A 3JRMO 3JYHA 1WATA 3T6GB 2XLVA 1UFBA 3FOOA 4U9EA 3EH2A 2L6HA 3H2VA 3TJ6A 3EHMA 3JT1A 1EI7A 3ZTMA 1GQAA 1G8XA 2QLAA 1K05A 4KBLA 4QIJA 4JWVA 4HFKB 1R5ID 2NG1A 2BC5A 2KGOA 5D92A 3NKEA 5DS4A 4O7GA 4M63A 1Q0MA 4ZLCA 3ASOC 4P9FA 4YJWA 2J9UA 3OWTA 3OA1A 2KSFA 1HW2A 5KYXB 2DI3A 1MQVA 3S29A 3RF3A 4NEKA 3Q6NA 4CJGA 3VF0A 5KYUB 4CJOA 4G7HF 3NYMA 2R03A 3MOYA 3RVYA 5L0GA 4IAOA 1T01A 4KNWA 1M6TA 3TK0A 4D4XA 1TWGA 4WCZA 1TWCA 1OXKA 2UZFA 1BBHA 3T88A 2DYRC 1M2VB 1WASA 1Q51A 4BJ6A 2KJGA 4JTDB 3AG4C 3S84A 1PD1A 1H9GA 4D4NA 3NYLA 4Q4ZF 4YT5A 3RW0A 3IHUA 3BEHA 3SWXA 3AQCA 3EG9A 3ZWIA 4ELXA 2NSFA 1A7VA 3C8ZA 2HMZA 1D1BA 1ORYA 2HSBA 3FAPB 4WGZA 3WG7C 4KNVA 4Z9IA 3NKDA 2ZXRA 1T5OA 2NPUA 3GM1A 3GWLA 1EQ1A 1L7CA 3PHF2 3SP1A 2ZXPA 1GS9A 4XWJA 2A0BA 2WL8A 1V55C 3G50A 2EILC 2Q9BA 2UUHA 3S28A 4N06A 1BR2A 3ZTZA 4AE4A 3LEVA 1NU7D 2VC9A 5F5FA 4DOZA 2EIJC 3U3FA 1LS4A 2QNLA 2PPYA 3ZDLA 5GPGB 4JE9A 1YAUO 2F6QA 3I47A 5T3WA 5IY5C 1OCRC 4FX5A 3U3BA 1NU9C 1RXQA 1Z63A 1T9KA 1JMWA 1TKNA 4EUKB 2EPNA 2ZPAA 2LIGA 1OR2A 1WTYA 2L7AA 2QE9A 2EINC 4MS2A 4CIHA 4J32B 2OU6A 2XSEA 4KI2A 1Z6AA 3DKAA 1ZHYA 3KMIA 4JCSA 4PFOA 1YLMA 5JBXA 5B3IA 1WGWA 3FXHA 3DMDA 4IZBA 2ZXOA 3MLGA 5A69A 2VCBA 3R0OA 1MMNA 4JJGA 3RIPA 1FFTC 2J45A 3IQCA 4LDRA 4LERA 1V74B 3B71A 1EA8A 4O6YA 1JXZA 3U2LA 3KL4A 1VMAA 4EBKA 3W8HB 4ANJA 1HMDA 1LI5A 5BUOA 3HINA 2KQ9A 3O4XE 3HLZA 3GM2A 1G4US 3W2WA 1YDIA 3LNRA 3R2PA 4R32A 1WZ8A 2JX0A 4IB4A 1L3PA 2ETSA 1SF8A 4WABA 3EGXB 3W8IB 3HKKA 2WZLA 2MWQA 3JTLO 1Z3IX 3EH1A 1JR8A 4IZDA 2PBPA 4W8PA 5JS5A 3UGPA 4PJLA 1TWAA 3IEEA 3I5QA 1LI7A 3POVA 3DI5A 3LS0A 4JOTA 3GANA 1RJNA 5L3QA 1I5NA 2Q4FA 1QLEC 4ZU2A 2IXMA 2LQGA 2MHRA 1JOGA 2R7TA 5DQZA 2J9BA 1Z7Qc 3FMSA 2XLMA 3HNJA 3RQEA 2KW3C 4YWQA 5E2QA 4OIOF 1ST6A 3K33A 3NYJA 1SR2A 2XXAB 1VLSA 3SZRA 3GORA 1RCPA 5F28E 1ZHZA 3W8IA 2IM8A 2ICWG 1RKEA 4MOUA 4EMLA 1YVIA 3I4UA 3KH2A 3M79A 1F1MA 3MFNA 2QQ3A 5A6KA 3G4ZA 4JYLA 4YT8A 1QKRA 2JPUA 3S0XA 2G3KA 2NSGA 4JEAA 3Q0JA 5T3TA 3KKBA 2EPKX 4IRUA 2Q3TA 4MQ9F 1ORSC 3VYWA 4ELSA 2NUPA 4IARA 5KYNA 2J9VA 2Y69C 2XLHA 4YL1A 2LCHA 3SXYA 1D1CA 2KNHA 4Z9JA 2XXAA 4MW8A 2X51A 3DM9B 5L0DA 2R7WA 3JRTA 5C9GA 2I8BA 4CX9A 2CW0F 3R9TA 3WODF 3NMIA 4K2NA 3NMKA 1LS1A 1Q0DA 3X2QC 5AC4A 3RSIA 1Q0GA 4P6IC 2A6HF 2HJ3A 2WZGA 2Y3GA 1BR1A 1J8MF 3K1IC 5HV9A 2ZQQA 4QIIA 3E70C 3O39A 3C18A 4CIPA 3MBGA 4IWBA 4O79A 2HMQA 5BQGA 3O10A 4DRJB 5EGYA 3UNGC 3DAGA 1UX5A 2QTVA 3DM5A 4Q5SF 4GEHB 4CSAC 4A2NB 3AGUA 3AQBA 4J7YA 5E3CA 1U0BB 3WAQA 1TQGA 3S9OA 4FAPB 3T89A 2YQYA 4UDVA 1QVXA 1EY3A 2AU5A 2HFIA 2XL6A 1ZYRF 4CS8C 2D5RB 3LEOA 2I15A 2O9XA 1UG7A 4X0RA 2IXPA 3CZ6A 3B9QA 2EIMC 2MYSA 4MVMA 5FZTA 3FVYA 4O6NA 1QSPA 3HRXA 3H2UA 1N1CA 2VH3A 2G62A 3QVZA 2YL7A 4YT4A 4XEVA 3BRJA 4WJ0A 4GEHA 3U9JA 2D4UA 1VTMP 4Q7CA 3QXZA 4OD5A 2NUTA 3J06A 3ZG1A 5F5HA 3ZC4A 4NTBA 1NG1A 1CGNA 3H02A 5DVWA 3DD7A 5A6AA 4MVUA 1LE2A 2EIKC 1JPNA 2A6EF 3T4RA 3IRBA 5AC5A 1ZU4A 2GWWA 1T6IA 4PACA 4H54A 2PX3A 1IZMA 4RD9A 4YN0B 2V3CC 1DOWA 2RD9A 5L0IA 3PZKA 1A41A 4E7ZA 4E17A 4OIQF 5EK0A 3EG9B 1HE9A 2XM4A 4U5DE 4QI0A 2Z15A 3AOUA 4MI2A 3IQ5A 4CBEA 1D1AA 4BEJA 5L0HA 1HE1A 4KNPA 4OIPF 1BZ4A 3VM6A 3LESA 1CPQA 2GA0A 3U8PA 4F4BA 3GWNA 1ZVZA 4XPWA 2DB4A
chains in the Genus database with same CATH topology
4XEVA 3BRJA 3A4MA 2HSBA 3GM3A 3U0CA 3L8JA 1JOGA 3RQFA 1OW8A 3GM1A 3A4LA 3JZ0A 1K04A 2L6FA 4XEKA 3RQEA 1V4AA 3C18A 3RQGA 1RJMA 1WWPA 3ADBA 5F28E 3B71A 3O10A 4XEFA 3IRBA 3JYYA 3ADCA 3C8GD 1ZZPA 1UX5A 1O3UA 1WOLA 4GEHB 1OW6A 3MFNA 4EBKA 3W8HB 2YWAA 2KK1A 2L6GA 3U3FA 2JPUA 3O4XE 4NQFA 2LK4A 1KTMA 1K40A 2P63A 3GM2A 3C8GB 3S9OA 1KNYA 4R32A 1QVXA 2JX0A 1UFBA 3TULA 2L6HA 1OW7A 3W8IB 1Y64B 3K7DA 3A4NA 2PBEA 1WTYA 1PV3A 1K05A 2Q00A 3L8IA 3AM1A 1UX4A 3ADDA 4EBJA 3AJMA 4NNQA 3C8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W8H B;  4XEV A;  3K7D A;  2YWA A;  1V4A A;  3C18 A;  3RQG A;  2KK1 A;  3BRJ A;  2L6G A;  2PBE A;  1WTY A;  3U3F A;  2JPU A;  1PV3 A;  2HSB A;  1WWP A;  4NQF A;  2LK4 A;  3GM3 A;  1KTM A;  5F28 E;  1K40 A;  3B71 A;  1K05 A;  2Q00 A;  3GM2 A;  3O10 A;  4XEF A;  3U0C A;  3C8G B;  3L8J A;  3S9O A;  1KNY A;  3JYY A;  4R32 A;  1QVX A;  3L8I A;  2JX0 A;  1JOG A;  3RQF A;  3C8G D;  1OW8 A;  1UFB A;  1ZZP A;  3GM1 A;  3JZ0 A;  4EBJ A;  3TUL A;  1K04 A;  2L6F A;  2L6H A;  1O3U A;  1WOL A;  4GEH B;  4XEK A;  1OW6 A;  3AJM A;  1OW7 A;  3MFN A;  3RQE A;  3W8I B;  3C8G A;  4EBK A; 
#chains in the Genus database with same CATH topology
 2YKZ A;  3V7O A;  4BJ6 C;  3F46 A;  3QVY A;  5E33 A;  5JSL A;  4AE4 B;  3L8J A;  3SNH A;  1V54 C;  4JW1 A;  3TOM A;  1YYJ A;  4RBN A;  3C62 A;  2RSE B;  4PJN A;  2YHS A;  2Y39 A;  1RJ9 A;  5K0I A;  2W45 A;  4JIO A;  1WWP A;  3ABL C;  1Q0K A;  3NDB B;  1TWH A;  3ECS A;  2GDC A;  5DS5 A;  4FZW A;  4CS9 A;  2TMV P;  1MMG A;  3FDU A;  4EWC A;  1E85 A;  1VOM A;  5AGF A;  4NY3 A;  4DVZ A;  4JZA A;  3SXM A;  3ABK C;  4A4A A;  2EPM X;  4AL1 A;  3RFY A;  1KNY A;  2L81 A;  4I42 A;  4DBQ A;  5KYW A;  2DYS C;  4JJF A;  3S90 A;  3DAF A;  4ULV A;  1NZE A;  1ZU5 A;  3ATP A;  3TQO A;  2G3V A;  3A4N A;  1SZI A;  3NRH A;  1FTS A;  5T1D B;  1ORJ A;  4PR9 A;  1YJG A;  5L0C A;  5JBW A;  3RYL A;  3L1M A;  3M1C B;  3L0I A;  3U8V A;  1NBB A;  1VYI A;  2EPL X;  3ASN C;  2OCC C;  4RDA A;  1FAP B;  5COG A;  3ZQY A;  2R7X A;  2Q9C A;  2L6F A;  2YL1 A;  2OOC A;  2AWY A;  2FFH A;  4LDQ A;  4MVQ A;  4BPM A;  1CGO A;  3UMI A;  3E9V A;  4U5H A;  2CDQ A;  2J8W A;  4U18 A;  1WOL A;  2PX0 A;  3KQF A;  5B1A C;  2IBF A;  4MW3 A;  4I4Z A;  2CGE A;  3SXZ A;  3LLI A;  2Q7R A;  3KPH A;  3QTH A;  2LK4 A;  1OKK A;  4JC7 A;  2B0H A;  1C03 A;  3B0P A;  2J46 A;  3W2V A;  3OC7 A;  4PJJ A;  2B0J A;  1PV3 A;  4U19 A;  2XLD A;  3CSK A;  3DE9 A;  2HZ8 A;  1VK5 A;  1AVO B;  1UX4 A;  2YVK A;  3X1O A;  4DRI B;  2FAP B;  1LPE A;  1T6Q A;  4MVR A;  1RKE B;  1CGM E;  2W4M A;  3IPM O;  2JD3 A;  5JT4 A;  3EPV A;  2XRH A;  1EF9 A;  2H7V C;  2R7U A;  3VRC A;  1FNT c;  5JRA A;  3L34 A;  4XEK A;  4PK4 A;  1A7D A;  3DWW A;  1OQC A;  1V4A A;  2XLE A;  5JUA A;  1C02 A;  2LFF A;  3KYI A;  3A9C A;  2J9W A;  1TFK B;  4GQH A;  3DJN B;  3PDM P;  2NUP B;  4EHP A;  4G7Z F;  2YL0 A;  4ONS A;  2P1A A;  1O3U A;  3FAJ A;  1MNE A;  2VCA A;  4G0H A;  4IJJ A;  1NFO A;  3ITF A;  1TR2 A;  2CNW A;  1H6G A;  4NQF A;  1OR3 A;  2P7V A;  4OG1 A;  3QW0 A;  4AX2 A;  1VB5 A;  1APC A;  4N6C A;  3K7D A;  3N0T A;  1DOV A;  1I4Z A;  2OJQ A;  4BJ5 A;  3LAY A;  3QMK A;  2P0N A;  4B6I A;  4C7O B;  1BDJ B;  4I44 A;  3GEE A;  1NFN A;  4YL0 A;  2YEV A;  2H7O A;  2GFH A;  4FWV A;  2HS5 A;  4IGG A;  4U5C E;  3LS1 A;  1Q0F A;  3HNK A;  4DBR A;  4N6H A;  1TFO B;  3EZI A;  3V5Z A;  1WN0 A;  3U5S A;  3M15 A;  1E86 A;  256B A;  3R7C A;  1O87 A;  2OEV A;  3IQT A;  3A4L A;  3JZ0 A;  4CDA A;  1K04 A;  3QK8 A;  1YAR O;  4MVZ A;  2R7Q A;  3N2Z B;  1OCO C;  3RQG A;  3P5M A;  2C03 A;  3ABM C;  1HZD A;  4L6R A;  2QY9 A;  3EHN A;  2GTR A;  4DVY P;  3K1H A;  3ADC A;  4JTA B;  4C3E A;  5TJ5 E;  1KU2 A;  5JLI A;  2XL8 A;  4C7O A;  5JVE A;  4OIR F;  4XPY A;  3K6B A;  1KTM A;  1EKY A;  3EQL F;  1FMV A;  1E84 A;  3SEO A;  2CCY A;  1OCC C;  1S7Z A;  3B29 A;  4YL3 A;  3T6B A;  3PCV A;  2J0W A;  1Y64 B;  3A11 A;  3MYI A;  3V5X A;  2NUT B;  5L0J A;  2XLO A;  3G4X A;  3AM1 A;  5DQT A;  2E87 A;  1D0X A;  2XM0 A;  2HV6 A;  3ADD A;  1M56 C;  2OG2 A;  4ULW A;  3C8G A;  2R7V A;  3T9O A;  2R02 A;  2M64 A;  4EIY A;  2HV7 A;  2M4E A;  2KC3 A;  1H7I A;  1W2W A;  2Q9A A;  2R7S A;  3NG1 A;  4E0I A;  4LLE A;  1XWJ A;  5CI9 A;  2R7O A;  5CIV A;  1Z23 A;  4GYT A;  1LVK A;  4XPX A;  4BG0 A;  2HKV A;  1NZY A;  5L0F A;  5KYY B;  2LFD A;  2A0U A;  4AL0 A;  4I1M A;  4MTG A;  3MX3 A;  3UMK A;  2KK1 A;  3VAY A;  1RKC A;  3TD7 A;  2VCC A;  3T6J A;  4HEA J;  4J30 B;  2W4B A;  1SMY F;  4BJT A;  4G7O F;  1YZA A;  5CI8 A;  3TUL A;  4K7B A;  4F47 A;  3CEX A;  3AG2 C;  1MJ3 A;  1Q52 A;  3IQ6 A;  4U5E E;  3TOL A;  2YLG A;  4NC3 A;  4JKV A;  3US6 A;  4G78 A;  5D91 A;  1DCI A;  3Q6M A;  1RJ9 B;  2H7B A;  2IYL D;  4U9D A;  3LUT B;  3R9S A;  1ZW3 A;  2AWC A;  1SYQ A;  1JAF A;  1YA9 A;  2J0X A;  2HSQ A;  1D0Z A;  2KYH A;  5KYY A;  4H4K C;  2R05 A;  1OKK D;  2CYD A;  5A6B D;  3GM3 A;  1O5H A;  3I5P A;  3NMJ A;  1DUB A;  4CDY A;  3ZQV A;  2IXN A;  2L9J A;  3T8A A;  4OD4 A;  4BJ1 A;  1D0Y A;  2AP3 A;  4JRZ A;  1GM5 A;  5KYW B;  1OXB A;  2GAQ A;  3CQZ A;  2ZQR A;  1MND A;  2PFD A;  1AUE A;  4I3M A;  1RJM A;  1HY5 A;  1M2O A;  5HSW A;  1GGQ A;  1QZX A;  1PD0 A;  3SXK A;  2PP4 A;  4XLN F;  2ZD9 A;  4E0H A;  3AGT A;  3GOD A;  4CS7 A;  5KYX A;  2XLW A;  3FHD A;  4MVO A;  4EBB A;  4E7S A;  2IXO A;  2A68 F;  3N24 A;  1OW7 A;  4FES A;  2H8A A;  3HTK C;  4FZW C;  1A0B A;  5KYU A;  4CS9 C;  5BQH A;  1J8Y F;  3K66 A;  4ZLD A;  2V26 A;  1Y4C A;  2Q00 A;  3DZA A;  3L8I A;  1T6U A;  3QW1 A;  1FFH A;  2LSE A;  4JCH A;  1B68 A;  1IW7 F;  4NNQ A;  2J7P D;  2CNW D;  2VRE A;  4IZC A;  4NCQ A;  1M2V A;  1VYK A;  5B1B C;  2IEX A;  3LNM B;  2WVO A;  5BQI A;  4DXW A;  3QXI A;  2XS1 A;  4CDV A;  4K1O A;  1LIH A;  1ZHW A;  3SLL A;  1M57 C;  2VAS A;  4MND A;  2OEX A;  2W9Y A;  2PNO A;  3AG3 C;  4O6M A;  5EHH A;  5FCL A;  1JPJ A;  4JEB A;  1YA7 O;  3GEH A;  3LJB A;  1ZHX A;  2LP4 A;  1ZHT A;  4N4W A;  3F47 A;  4JUR I;  1CPR A;  4AK9 A;  5DS6 A;  1LE4 A;  1OW6 A;  2Y3D A;  3H65 A;  3FDQ A;  2L6G A;  2YZS A;  5L3V A;  3EZH A;  1FR0 A;  1ZW2 A;  1XZP A;  2HJM A;  3V5Y A;  2XS8 A;  2P6V A;  1YZC A;  3PMR A;  2BE5 F;  3DXJ F;  3SYN A;  1NLX A;  2UUI A;  1G4W R;  5DLJ A;  3Q0G A;  2ASR A;  3U9M A;  1QPU A;  5A6B A;  4C3B A;  2OQM A;  2EJ5 A;  4YT2 A;  5E3A A;  4LAC B;  3HNI A;  1LKX A;  1PCX A;  2FW2 A;  3Q1T A;  3A4M A;  2WVQ A;  4OLQ A;  4QI2 A;  4LDK A;  1G5Z A;  3U0C A;  2HUJ A;  4ELW A;  3JSZ A;  1E83 A;  2ZXW C;  4JTC B;  1OW8 A;  2A1D D;  1VLT A;  4JVS A;  4NTF A;  3RVZ A;  3KYJ A;  2EPO A;  3TRR A;  1OCZ C;  3HNL A;  4HFF B;  3LLK A;  3ZIB A;  4C3D A;  5KJP A;  2A69 F;  4ER9 A;  3C8G D;  2HW5 A;  4NTA A;  2AVK A;  3EGD B;  2DGJ A;  1QQ3 A;  4OIN F;  4YK5 A;  1I4Y A;  4HE8 D;  2YLI A;  2LD6 A;  3M4C A;  3RKO F;  1E2X A;  2F22 A;  5JP7 A;  2OKU A;  3UMH A;  5B3S C;  2QUP A;  1BR4 A;  2P61 A;  4U5B E;  2J7P A;  2R9R B;  4Z9H A;  1LM3 B;  3W8H A;  4JFC A;  4I1O B;  4MVS A;  3Q7G A;  3UGO A;  2PF4 E;  4EBJ A;  3AJM A;  2R25 A;  3TJ5 A;  2VX2 A;  1HMO A;  1U6H A;  1U89 A;  3EGX A;  4P9T A;  2X0C A;  2R7R A;  1R4T A;  3MYF A;  1EF8 A;  1S05 A;  3Q7L A;  3B0V C;  3C7J A;  4BJ5 C;  3HJC A;  3EFO B;  3EGD A;  1JRA A;  1YYX A;  1UIY A;  4DJ9 A;  4DRH B;  2OJE D;  1RMV A;  4XLP F;  3CAX A;  3DE8 A;  2WZF A;  4MTO A;  4XEF A;  1XZQ A;  3WHN A;  1FMW A;  4WGY A;  2VB6 A;  4W8K A;  4JCZ A;  1ZZP A;  4BEM J;  1Y6D A;  4IAQ A;  4FJW D;  2YL3 A;  4PFP A;  4U1A A;  3O6X A;  4K3W A;  3GEI A;  2FGY A;  3AG1 C;  4J7T A;  1K40 A;  2P63 A;  2YLD A;  3C8G B;  2XL4 A;  4PJM A;  4E18 A;  1NSG B;  4U5G A;  3O55 A;  3H81 A;  1Z5Z A;  3QZC A;  4EKW A;  2Y3B A;  2PBE A;  2BL2 A;  3EFO A;  1MMA A;  1MMD A;  3K1I A;  4QDL A;  3FOP A;  3EJN A;  3UR3 C;  1NZY B;  4LLC A;  4KC9 A;  1AEP A;  2C04 A;  4XTK A;  4CSA A;  1C17 M;  3M4B A;  5A6J A;  3RQF A;  4XQ1 A;  1A7E A;  3ZVR A;  3OEO A;  1H9T A;  5COF A;  2WVN A;  3W4Y A;  5COM A;  3S27 A;  2FBM A;  2WB7 A;  3ADB A;  3DJU B;  3JCU Q;  3RH3 A;  3JYY A;  4MTF A;  3MYB A;  3ZSU A;  2Y3H A;  3U2M A;  3C63 A;  4U5F E;  4I52 A;  2IOQ A;  4CS8 A;  3JSE O;  2YRF A;  2DUB A;  3TLF A;  2YWA A;  1HW1 A;  4K0D A;  3B0U X;  3G64 A;  3JRM O;  3JYH A;  1WAT A;  3T6G B;  2XLV A;  1UFB A;  3FOO A;  4U9E A;  3EH2 A;  2L6H A;  3H2V A;  3TJ6 A;  3EHM A;  3JT1 A;  1EI7 A;  3ZTM A;  1GQA A;  1G8X A;  2QLA A;  1K05 A;  4KBL A;  4QIJ A;  4JWV A;  4HFK B;  1R5I D;  2NG1 A;  2BC5 A;  2KGO A;  5D92 A;  3NKE A;  5DS4 A;  4O7G A;  4M63 A;  1Q0M A;  4ZLC A;  3ASO C;  4P9F A;  4YJW A;  2J9U A;  3OWT A;  3OA1 A;  2KSF A;  1HW2 A;  5KYX B;  2DI3 A;  1MQV A;  3S29 A;  3RF3 A;  4NEK A;  3Q6N A;  4CJG A;  3VF0 A;  5KYU B;  4CJO A;  4G7H F;  3NYM A;  2R03 A;  3MOY A;  3RVY A;  5L0G A;  4IAO A;  1T01 A;  4KNW A;  1M6T A;  3TK0 A;  4D4X A;  1TWG A;  4WCZ A;  1TWC A;  1OXK A;  2UZF A;  1BBH A;  3T88 A;  2DYR C;  1M2V B;  1WAS A;  1Q51 A;  4BJ6 A;  2KJG A;  4JTD B;  3AG4 C;  3S84 A;  1PD1 A;  1H9G A;  4D4N A;  3NYL A;  4Q4Z F;  4YT5 A;  3RW0 A;  3IHU A;  3BEH A;  3SWX A;  3AQC A;  3EG9 A;  3ZWI A;  4ELX A;  2NSF A;  1A7V A;  3C8Z A;  2HMZ A;  1D1B A;  1ORY A;  2HSB A;  3FAP B;  4WGZ A;  3WG7 C;  4KNV A;  4Z9I A;  3NKD A;  2ZXR A;  1T5O A;  2NPU A;  3GM1 A;  3GWL A;  1EQ1 A;  1L7C A;  3PHF 2;  3SP1 A;  2ZXP A;  1GS9 A;  4XWJ A;  2A0B A;  2WL8 A;  1V55 C;  3G50 A;  2EIL C;  2Q9B A;  2UUH A;  3S28 A;  4N06 A;  1BR2 A;  3ZTZ A;  4AE4 A;  3LEV A;  1NU7 D;  2VC9 A;  5F5F A;  4DOZ A;  2EIJ C;  3U3F A;  1LS4 A;  2QNL A;  2PPY A;  3ZDL A;  5GPG B;  4JE9 A;  1YAU O;  2F6Q A;  3I47 A;  5T3W A;  5IY5 C;  1OCR C;  4FX5 A;  3U3B A;  1NU9 C;  1RXQ A;  1Z63 A;  1T9K A;  1JMW A;  1TKN A;  4EUK B;  2EPN A;  2ZPA A;  2LIG A;  1OR2 A;  1WTY A;  2L7A A;  2QE9 A;  2EIN C;  4MS2 A;  4CIH A;  4J32 B;  2OU6 A;  2XSE A;  4KI2 A;  1Z6A A;  3DKA A;  1ZHY A;  3KMI A;  4JCS A;  4PFO A;  1YLM A;  5JBX A;  5B3I A;  1WGW A;  3FXH A;  3DMD A;  4IZB A;  2ZXO A;  3MLG A;  5A69 A;  2VCB A;  3R0O A;  1MMN A;  4JJG A;  3RIP A;  1FFT C;  2J45 A;  3IQC A;  4LDR A;  4LER A;  1V74 B;  3B71 A;  1EA8 A;  4O6Y A;  1JXZ A;  3U2L A;  3KL4 A;  1VMA A;  4EBK A;  3W8H B;  4ANJ A;  1HMD A;  1LI5 A;  5BUO A;  3HIN A;  2KQ9 A;  3O4X E;  3HLZ A;  3GM2 A;  1G4U S;  3W2W A;  1YDI A;  3LNR A;  3R2P A;  4R32 A;  1WZ8 A;  2JX0 A;  4IB4 A;  1L3P A;  2ETS A;  1SF8 A;  4WAB A;  3EGX B;  3W8I B;  3HKK A;  2WZL A;  2MWQ A;  3JTL O;  1Z3I X;  3EH1 A;  1JR8 A;  4IZD A;  2PBP A;  4W8P A;  5JS5 A;  3UGP A;  4PJL A;  1TWA A;  3IEE A;  3I5Q A;  1LI7 A;  3POV A;  3DI5 A;  3LS0 A;  4JOT A;  3GAN A;  1RJN A;  5L3Q A;  1I5N A;  2Q4F A;  1QLE C;  4ZU2 A;  2IXM A;  2LQG A;  2MHR A;  1JOG A;  2R7T A;  5DQZ A;  2J9B A;  1Z7Q c;  3FMS A;  2XLM A;  3HNJ A;  3RQE A;  2KW3 C;  4YWQ A;  5E2Q A;  4OIO F;  1ST6 A;  3K33 A;  3NYJ A;  1SR2 A;  2XXA B;  1VLS A;  3SZR A;  3GOR A;  1RCP A;  5F28 E;  1ZHZ A;  3W8I A;  2IM8 A;  2ICW G;  1RKE A;  4MOU A;  4EML A;  1YVI A;  3I4U A;  3KH2 A;  3M79 A;  1F1M A;  3MFN A;  2QQ3 A;  5A6K A;  3G4Z A;  4JYL A;  4YT8 A;  1QKR A;  2JPU A;  3S0X A;  2G3K A;  2NSG A;  4JEA A;  3Q0J A;  5T3T A;  3KKB A;  2EPK X;  4IRU A;  2Q3T A;  4MQ9 F;  1ORS C;  3VYW A;  4ELS A;  2NUP A;  4IAR A;  5KYN A;  2J9V A;  2Y69 C;  2XLH A;  4YL1 A;  2LCH A;  3SXY A;  1D1C A;  2KNH A;  4Z9J A;  2XXA A;  4MW8 A;  2X51 A;  3DM9 B;  5L0D A;  2R7W A;  3JRT A;  5C9G A;  2I8B A;  4CX9 A;  2CW0 F;  3R9T A;  3WOD F;  3NMI A;  4K2N A;  3NMK A;  1LS1 A;  1Q0D A;  3X2Q C;  5AC4 A;  3RSI A;  1Q0G A;  4P6I C;  2A6H F;  2HJ3 A;  2WZG A;  2Y3G A;  1BR1 A;  1J8M F;  3K1I C;  5HV9 A;  2ZQQ A;  4QII A;  3E70 C;  3O39 A;  3C18 A;  4CIP A;  3MBG A;  4IWB A;  4O79 A;  2HMQ A;  5BQG A;  3O10 A;  4DRJ B;  5EGY A;  3UNG C;  3DAG A;  1UX5 A;  2QTV A;  3DM5 A;  4Q5S F;  4GEH B;  4CSA C;  4A2N B;  3AGU A;  3AQB A;  4J7Y A;  5E3C A;  1U0B B;  3WAQ A;  1TQG A;  3S9O A;  4FAP B;  3T89 A;  2YQY A;  4UDV A;  1QVX A;  1EY3 A;  2AU5 A;  2HFI A;  2XL6 A;  1ZYR F;  4CS8 C;  2D5R B;  3LEO A;  2I15 A;  2O9X A;  1UG7 A;  4X0R A;  2IXP A;  3CZ6 A;  3B9Q A;  2EIM C;  2MYS A;  4MVM A;  5FZT A;  3FVY A;  4O6N A;  1QSP A;  3HRX A;  3H2U A;  1N1C A;  2VH3 A;  2G62 A;  3QVZ A;  2YL7 A;  4YT4 A;  4XEV A;  3BRJ A;  4WJ0 A;  4GEH A;  3U9J A;  2D4U A;  1VTM P;  4Q7C A;  3QXZ A;  4OD5 A;  2NUT A;  3J06 A;  3ZG1 A;  5F5H A;  3ZC4 A;  4NTB A;  1NG1 A;  1CGN A;  3H02 A;  5DVW A;  3DD7 A;  5A6A A;  4MVU A;  1LE2 A;  2EIK C;  1JPN A;  2A6E F;  3T4R A;  3IRB A;  5AC5 A;  1ZU4 A;  2GWW A;  1T6I A;  4PAC A;  4H54 A;  2PX3 A;  1IZM A;  4RD9 A;  4YN0 B;  2V3C C;  1DOW A;  2RD9 A;  5L0I A;  3PZK A;  1A41 A;  4E7Z A;  4E17 A;  4OIQ F;  5EK0 A;  3EG9 B;  1HE9 A;  2XM4 A;  4U5D E;  4QI0 A;  2Z15 A;  3AOU A;  4MI2 A;  3IQ5 A;  4CBE A;  1D1A A;  4BEJ A;  5L0H A;  1HE1 A;  4KNP A;  4OIP F;  1BZ4 A;  3VM6 A;  3LES A;  1CPQ A;  2GA0 A;  3U8P A;  4F4B A;  3GWN A;  1ZVZ A;  4XPW A;  2DB4 A; 
#chains in the Genus database with same CATH homology
 4XEV A;  3BRJ A;  3A4M A;  2HSB A;  3GM3 A;  3U0C A;  3L8J A;  1JOG A;  3RQF A;  1OW8 A;  3GM1 A;  3A4L A;  3JZ0 A;  1K04 A;  2L6F A;  4XEK A;  3RQE A;  1V4A A;  3C18 A;  3RQG A;  1RJM A;  1WWP A;  3ADB A;  5F28 E;  3B71 A;  3O10 A;  4XEF A;  3IRB A;  3JYY A;  3ADC A;  3C8G D;  1ZZP A;  1UX5 A;  1O3U A;  1WOL A;  4GEH B;  1OW6 A;  3MFN A;  4EBK A;  3W8H B;  2YWA A;  2KK1 A;  2L6G A;  3U3F A;  2JPU A;  3O4X E;  4NQF A;  2LK4 A;  1KTM A;  1K40 A;  2P63 A;  3GM2 A;  3C8G B;  3S9O A;  1KNY A;  4R32 A;  1QVX A;  2JX0 A;  1UFB A;  3TUL A;  2L6H A;  1OW7 A;  3W8I B;  1Y64 B;  3K7D A;  3A4N A;  2PBE A;  1WTY A;  1PV3 A;  1K05 A;  2Q00 A;  3L8I A;  3AM1 A;  1UX4 A;  3ADD A;  4EBJ A;  3AJM A;  4NNQ A;  3C8G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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