3L8JA

Crystal structure of ccm3, a cerebral cavernous malformation protein critical for vascular integrity
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
200
structure length
200
Chain Sequence
XXXTTSMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFVSANRLIHQTNLILQTFKT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Programmed cell death protein 10
total genus 75
structure length 200
sequence length 200
ec nomenclature
pdb deposition date 2009-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06840 DUF1241 Protein of unknown function (DUF1241)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 3l8jA01
1.20.120.330 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Nucleotidyltransferases domain 2 3l8jA02
3W8IB 3GM1A 3BRJA 4R32A 4XEKA 3U3FA 4XEFA 3U0CA 1K05A 2Q00A 1KNYA 3AJMA 2JX0A 1OW8A 1UFBA 1O3UA 3RQEA 3JYYA 1K40A 3L8JA 3C8GA 2L6GA 1WTYA 1PV3A 2L6FA 3MFNA 3RQFA 3TULA 2PBEA 3JZ0A 3C8GD 3W8HB 1QVXA 1WOLA 1ZZPA 5F28E 2HSBA 3GM3A 2L6HA 3K7DA 4EBKA 1KTMA 3L8IA 3RQGA 1OW6A 4GEHB 3C8GB 3S9OA 2KK1A 2JPUA 3GM2A 2LK4A 1WWPA 1V4AA 1K04A 3O10A 4NQFA 3C18A 4XEVA 4EBJA 3B71A 1JOGA 2YWAA 1OW7A
chains in the Genus database with same CATH superfamily
1YJGA 1Z23A 4JKVA 3FOOA 4GEHA 4WCZA 1PCXA 1T9KA 1VOMA 1Y4CA 1QVXA 3RW0A 1FR0A 1LS1A 4EMLA 3GANA 2R7SA 4FWVA 3QXIA 2HJMA 1GM5A 5B1BC 5KYNA 3RH3A 3KMIA 3V7OA 4U5GA 4MTOA 1HZDA 4YT8A 5BQIA 2M64A 1RKEB 2I8BA 1NSGB 1Q51A 1TWGA 1YZAA 3QW1A 1BR2A 1RKEA 2AWYA 3S0XA 4AE4B 3TULA 3AG2C 4YL3A 4CSAA 4EWCA 2R25A 3T6BA 4MNDA 2NUPB 1Z6AA 1OW7A 4AE4A 1ORSC 3HNIA 3CEXA 3U0CA 1AVOB 4RDAA 4CS8C 1O5HA 2VCBA 1HE9A 1MMAA 4MW8A 2NUPA 4E17A 2H7VC 3EQLF 1A7VA 3RSIA 1PD0A 3O39A 1QPUA 3NYMA 2KW3C 2WL8A 2VCAA 2HFIA 3Q6NA 3QXZA 2IEXA 4U5FE 1SZIA 3ITFA 4DRIB 1ZHWA 5T3WA 4H4KC 4Z9HA 1LVKA 3VAYA 1WATA 4EBKA 3EPVA 3SZRA 2QTVA 2VX2A 4G7HF 3HNKA 4IJJA 2TMVP 2A0BA 1JXZA 4OIQF 3V5ZA 4N4WA 3PZKA 4JYLA 2MWQA 5L0DA 1YA7O 5JP7A 3MFNA 4Q7CA 4DXWA 4O6MA 1ST6A 2J9WA 2EIMC 3K7DA 3NMKA 1U0BB 2A68F 1HMOA 5COGA 4D4NA 3CAXA 1NU9C 3R0OA 2R7RA 3LAYA 4D4XA 3ZTZA 5A6BD 4JOTA 1F1MA 5GPGB 1CPQA 4CIPA 1CGNA 4LDKA 3MYIA 5D91A 1L3PA 4U5HA 3GM3A 2HMQA 1UX4A 2HS5A 4K0DA 3WHNA 4K3WA 2J9BA 2IXNA 4CIHA 2H7OA 2XRHA 4BEMJ 3R9TA 5BQGA 3SEOA 2OJQA 4N6CA 1Q0MA 3VRCA 2CW0F 5L3VA 1DOWA 3O10A 1UG7A 3ADDA 1YARO 1D1CA 3T88A 3IQTA 1ORJA 3PHF2 2MHRA 3S27A 1AEPA 4W8PA 3A4NA 5DQZA 1LE2A 2IXOA 2YZSA 2R7XA 5A6KA 3TRRA 5KYUB 2R7VA 2RSEB 3NMJA 3NYLA 1RMVA 2HUJA 4ELWA 5KYUA 1LI7A 3EG9B 3W8HB 3F46A 2OJED 3M4BA 5B3SC 1TWCA 3JRMO 4JRZA 3NG1A 1NLXA 2F6QA 1WN0A 2HKVA 3L1MA 3EG9A 3W8HA 2ETSA 1H9TA 3TQOA 2Q00A 3ADCA 3MX3A 3NRHA 4QDLA 4GYTA 2J8WA 4HEAJ 4I44A 4KC9A 1T6IA 2A6HF 3C62A 5A69A 1BDJB 1S7ZA 1K04A 4K7BA 4G78A 4W8KA 1OCCC 1SF8A 2YLDA 4BJTA 3G50A 2B0JA 4NCQA 2ICWG 3CQZA 2Q4FA 3JCUQ 2CNWD 2LK4A 4JEBA 3C8ZA 2EJ5A 3KQFA 3AGTA 2EILC 2QNLA 3AOUA 3RYLA 4O7GA 5L0GA 1WTYA 1YA9A 1OCOC 2OEXA 3K1IA 3ABKC 3O4XE 2YL1A 2O9XA 1KU2A 2KC3A 2DI3A 3DE8A 3ECSA 5JLIA 1RJMA 3FAPB 3U3FA 4XEFA 2R7UA 1N1CA 1OKKD 5BUOA 3MYBA 3KH2A 4I1MA 2D5RB 1S05A 4P9TA 4ULWA 3EH1A 3T8AA 4OIPF 3X2QC 2M4EA 1TR2A 2BL2A 4MOUA 4OIOF 3RVYA 3BEHA 4FZWC 2UZFA 4I52A 2E87A 1U89A 2XLEA 1APCA 3GWLA 4YL1A 3M15A 3V5XA 3K1HA 3DM5A 4OIRF 1I5NA 1B68A 2G3VA 2PX0A 2XM4A 4JW1A 1OW6A 2R9RB 3NDBB 1CPRA 3HNLA 3UR3C 4JC7A 3JYHA 1MMNA 1LIHA 4XQ1A 1NFOA 3R2PA 2KJGA 4U5DE 3NYJA 2DYSC 2QY9A 3CZ6A 3TK0A 2JD3A 3UGOA 2EPNA 4JTCB 1FFHA 4CBEA 4C3DA 4RD9A 2YLGA 3AG1C 2XLDA 3DAGA 2EPKX 1LM3B 2DGJA 3ZQVA 4IZDA 3A4MA 2ASRA 4DBRA 3J06A 4G0HA 3KL4A 4HFKB 3TD7A 1SMYF 2HW5A 2XL6A 2P61A 4Z9JA 2NG1A 3U2LA 4N06A 4B6IA 3ZC4A 3GM1A 3AG4C 1ZU4A 3B0UX 3JYYA 1HE1A 3EGXB 4IAOA 5JS5A 3K66A 2QLAA 4BJ5A 3FVYA 5CIVA 3NKDA 1A7DA 4LACB 1M56C 3EGXA 3OC7A 2FGYA 2EIKC 5KYXB 5COMA 4CJGA 5E3AA 4JVSA 3U8PA 2WVNA 2YLIA 3TOMA 2VCCA 3HTKC 5JSLA 2XS1A 1GS9A 1U6HA 5KYXA 1I4ZA 3LS1A 4NTBA 1RKCA 1ZW2A 4DJ9A 1OCRC 1D0XA 1YAUO 2KGOA 5TJ5E 1M2OA 2ZXWC 2Y39A 1DOVA 1UFBA 3S29A 5FZTA 2VB6A 4N6HA 1TFKB 1Z3IX 3K6BA 2OKUA 4KNPA 2ZPAA 4ULVA 3AG3C 4XPYA 3LLKA 4E7SA 2Q9CA 3NKEA 3RVZA 4O6YA 5COFA 1D0ZA 2DYRC 4FAPB 3G64A 4DOZA 2P63A 3S84A 3US6A 4MW3A 4IGGA 2UUIA 2XLOA 3I4UA 4FZWA 3C8GB 4LDRA 2GTRA 2X51A 3RIPA 5A6BA 1JPNA 5F5FA 4MTFA 3U9MA 3V5YA 4DRJB 2XS8A 2JX0A 4J30B 4ER9A 4PACA 3C8GA 4GQHA 1C17M 4K2NA 1FNTc 3T89A 3DE9A 2LIGA 4CS9C 2R7WA 5L0JA 1A7EA 4C3BA 1NBBA 2P6VA 2J9UA 3AJMA 1OW8A 2ZXOA 3QVYA 1OXBA 2Y3HA 2NSGA 3S28A 4YN0B 1V55C 2WVOA 1LS4A 4UDVA 3B9QA 2AVKA 1D1BA 4OG1A 3W8IB 5JT4A 2BE5F 4IRUA 3QTHA 4HE8D 3H2UA 2A69F 2ZXPA 3I5QA 3W8IA 5F28E 2CCYA 3L8IA 2LCHA 2HV7A 3Q7LA 3ASNC 1OR2A 3JSEO 1JOGA 4AK9A 4NY3A 2Q9BA 4CDYA 3BRJA 5JBXA 2Y3DA 2G3KA 4CX9A 2LFDA 3DMDA 2PBEA 4NTAA 2PX3A 2L81A 1MNDA 4JCSA 2LQGA 2W4BA 3QVZA 1ZYRF 3DXJF 1OXKA 2WZLA 4A2NB 1YDIA 1K40A 1FTSA 2NSFA 4EUKB 4YL0A 1RXQA 3ZTMA 3W4YA 2Z15A 4IZBA 3HJCA 2XLWA 2VH3A 3LS0A 2FAPB 1G8XA 5BQHA 4PJJA 4ANJA 2LD6A 4IZCA 3S90A 2L6FA 5C9GA 3TJ5A 1ZZPA 5T3TA 3GM2A 3H02A 2EPLX 3SP1A 3U2MA 3B0VC 1EA8A 4MVZA 4KBLA 4FESA 4IARA 2IBFA 1D0YA 1VYIA 4JURI 4PFPA 1YLMA 3U3BA 5EHHA 3SXZA 1NFNA 1V4AA 2R7TA 1L7CA 4AL1A 1IZMA 4XEKA 3LNMB 2HMZA 1AUEA 2V3CC 2OG2A 4U9EA 1T6QA 1QKRA 1EF8A 2WZFA 2OEVA 3N2ZB 3Q1TA 1ZHXA 4WGYA 3ZVRA 4A4AA 5DLJA 3RKOF 3MBGA 3O55A 5L3QA 5JUAA 1G5ZA 4BG0A 4JCHA 2OU6A 3I47A 4BJ6C 3O6XA 4CS8A 1VK5A 2HZ8A 1V54C 4G7ZF 3SXKA 2YL0A 4ELSA 2MYSA 4ZLDA 1WZ8A 5A6AA 4KI2A 3L0IA 1J8MF 3FMSA 2PF4E 2HJ3A 3EJNA 4C7OB 3VM6A 3EZHA 5L0FA 2VC9A 3Q6MA 1MJ3A 3JSZA 4C7OA 3Q0GA 1MNEA 2KK1A 4YJWA 3UMHA 2W4MA 2EPMX 2FBMA 2Q9AA 1MMDA 2QUPA 5E2QA 3JT1A 4XWJA 3T6GB 5K0IA 1NG1A 4FJWD 3P5MA 3DM9B 5L0CA 4KNVA 4PJMA 3B71A 3FHDA 1GQAA 2YQYA 5DS4A 4RBNA 1ORYA 3OEOA 3G4ZA 2GWWA 5T1DB 1QSPA 2PFDA 3G4XA 4OD4A 2X0CA 2QQ3A 2AWCA 4E0HA 1JRAA 1ZHYA 2YVKA 4OLQA 4NTFA 4EKWA 4YT2A 4F47A 1E83A 1E86A 1CGOA 3ZG1A 3MYFA 3SNHA 1M57C 2L6GA 5KYYB 2LSEA 4U5CE 3QW0A 1ZHZA 3SLLA 3HRXA 2Q3TA 3KYJA 2CYDA 1LI5A 5KYYA 1VTMP 4ZLCA 3GODA 3IPMO 1NZEA 1E2XA 3U5SA 4ELXA 4CSAC 4J7TA 2V26A 3KYIA 3IEEA 2C04A 3F47A 3FOPA 1W2WA 1Q0KA 3H65A 256BA 4I3MA 4JIOA 3CSKA 4XPXA 4DRHB 2YEVA 1FMWA 1TKNA 4R32A 5KJPA 4QIJA 2XM0A 2OCCC 1VYKA 1Q0GA 2CDQA 2PBPA 1Z5ZA 1PV3A 4LLEA 5HV9A 3B0PA 1XWJA 4QI0A 2A0UA 2PP4A 4U19A 4XLPF 1VLSA 3C18A 4K1OA 3UGPA 1DUBA 2EPOA 3L34A 3AM1A 1TWHA 4U1AA 5CI8A 5CI9A 4E7ZA 4JEAA 3SXMA 1R5ID 4YT5A 2PNOA 1GGQA 1UIYA 4MVUA 2OOCA 3JTLO 2BC5A 4NEKA 2J0XA 4CS7A 3ATPA 3E70C 2IYLD 2KYHA 2WVQA 3L8JA 3ADBA 2KSFA 1H9GA 5F5HA 3H2VA 3A11A 3QK8A 2KNHA 2YL7A 2I15A 4IWBA 5AC5A 3U9JA 1QZXA 1G4US 3AQBA 4PFOA 3RQEA 3ASOC 4X0RA 3IHUA 3N0TA 2IXPA 4U5EE 5HSWA 1EKYA 4XLNF 4JFCA 4JWVA 3JRTA 1C02A 3LLIA 3OWTA 1VMAA 3HINA 4U9DA 4ZU2A 4WGZA 1JMWA 3FDQA 1OR3A 1HY5A 3W2VA 4IB4A 3N24A 2Y3GA 3TOLA 2ZQQA 3ZIBA 2JPUA 4EBJA 2XL4A 2PPYA 1ZVZA 1NZYB 1Q0DA 4CDVA 2ZQRA 3PDMP 4JZAA 1PD1A 1YYXA 2J7PD 1KTMA 3T6JA 1NZYA 3FDUA 4MS2A 4G7OF 4MI2A 3VYWA 4AX2A 2GAQA 1Z7Qc 1QLEC 4NC3A 2R02A 2P7VA 2AP3A 1LE4A 1O87A 3EZIA 3LESA 4QI2A 2XL8A 1ZU5A 5AGFA 1SR2A 1O3UA 1TWAA 1ZHTA 3ABLC 1DCIA 4M63A 4Z9IA 3WAQA 2A6EF 4J32B 4NQFA 1T5OA 2C03A 2XSEA 1K05A 1EY3A 2XLHA 2AU5A 3K1IC 2P0NA 3Q7GA 5KYWB 4MVOA 2L6HA 3R7CA 4EBBA 1BBHA 2W45A 4I4ZA 4JE9A 4LDQA 5E33A 4EIYA 3QZCA 3EH2A 2P1AA 2F22A 1BR1A 1FFTC 4XPWA 1R4TA 5KYWA 3ABMC 3M1CB 1ZW3A 2L7AA 3POVA 3DZAA 5D92A 1JR8A 2XXAB 3DJUB 4P9FA 1XZPA 3C8GD 5A6JA 4XTKA 2CNWA 4AL0A 1OCZC 2GFHA 2XXAA 5B1AC 4P6IC 2YRFA 3HNJA 2RD9A 1Q0FA 1G4WR 1RJ9B 4H54A 3IQCA 4YK5A 4FX5A 1WGWA 3GWNA 3LEVA 2EINC 3U8VA 1HMDA 3RF3A 1T6UA 2J46A 3H81A 2EIJC 2HSQA 1RJ9A 4JCZA 2DB4A 1OKKA 2H8AA 5AC4A 4IAQA 1C03A 4L6RA 2WB7A 4Q4ZF 1NU7D 1A0BA 3OA1A 3WG7C 3GEIA 3T4RA 3UMKA 4KNWA 2Y3BA 2B0HA 4JTAB 2J9VA 4DVZA 1I4YA 3ZDLA 1EQ1A 1V74B 1T01A 3B29A 1MMGA 3HLZA 1BR4A 1Y64B 4J7YA 4CS9A 1BZ4A 1FAPB 3ZSUA 4O79A 1VB5A 1IW7F 2R03A 3PMRA 3FXHA 4I42A 2IXMA 1Z63A 2J45A 2LFFA 4O6NA 5E3CA 3SXYA 2HV6A 2A1DD 2VASA 4MVRA 4BEJA 1WASA 3M79A 1YYJA 4MQ9F 4OD5A 2GA0A 3HKKA 1EF9A 4BJ5C 4JJFA 3S9OA 3A9CA 3UMIA 5L0HA 1JAFA 3IRBA 2Y69C 1MQVA 2XLMA 4EHPA 2QE9A 3FAJA 4MVMA 1M2VB 5IY5C 2GDCA 5JRAA 2R7OA 1Q52A 2NUTB 4PR9A 5DS6A 3X1OA 4I1OB 4XEVA 5DS5A 1M2VA 5FCLA 3EFOB 2VREA 1LPEA 2NUTA 3LNRA 3DWWA 5EK0A 2DUBA 2WZGA 3EGDB 1QQ3A 4JJGA 3KPHA 2HSBA 2OQMA 3EFOA 3M4CA 3EGDA 2J0WA 5DVWA 3WODF 4F4BA 1CGME 4C3EA 1H6GA 4HFFB 1JPJA 3NMIA 2IOQA 3LEOA 1M6TA 3DI5A 2R05A 3A4LA 3QMKA 1OQCA 1WWPA 3AGUA 3MLGA 2W9YA 2FFHA 3E9VA 1RCPA 3AQCA 4YT4A 4LERA 1LKXA 4WJ0A 2YHSA 4E0IA 5JBWA 4JTDB 1A41A 1KNYA 3LUTB 2R7QA 3MOYA 3KKBA 4MVSA 3I5PA 2D4UA 3R9SA 2L9JA 2LP4A 1E84A 1VLTA 1XZQA 1YVIA 1YZCA 5L0IA 4MTGA 4U18A 2NPUA 4PJNA 1E85A 2G62A 3IQ5A 3PCVA 4BJ1A 3DAFA 3IQ6A 4BPMA 1D1AA 4U5BE 4CJOA 4MVQA 1Y6DA 3RQGA 3TLFA 3GEHA 3DD7A 1HW1A 4ONSA 3UNGC 3TJ6A 1J8YF 4Q5SF 3T9OA 4CDAA 5EGYA 1HW2A 3RFYA 5DQTA 3GEEA 2ZD9A 3JZ0A 4WABA 1RJNA 4PK4A 1SYQA 2FW2A 3K33A 4DBQA 2YKZA 2ZXRA 4E18A 3C7JA 1H7IA 3EHNA 3EHMA 4BJ6A 2J7PA 1EI7A 2H7BA 2IM8A 3W2WA 3GORA 4PJLA 3VF0A 1TFOB 2XLVA 3DJNB 3Q0JA 1UX5A 4DVYP 3ZWIA 4LLCA 2CGEA 5JVEA 3ZQYA 3C63A 3LJBA 4YWQA 2KQ9A 5B3IA 4NNQA 2Q7RA 4QIIA 1TQGA 3SWXA 1FMVA 2UUHA 3RQFA 4OINF 3DKAA 1WOLA 4GEHB 3SYNA 2YL3A 2YWAA
chains in the Genus database with same CATH topology
3AJMA 1OW8A 3A4NA 3AM1A 2L6GA 1WTYA 2L6FA 3JZ0A 3O4XE 1QVXA 1ZZPA 2HSBA 4EBKA 1KTMA 3GM2A 1RJMA 1Y64B 3W8IB 3U3FA 4XEFA 1UFBA 3L8JA 3ADBA 3MFNA 3C8GD 3W8HB 3A4LA 5F28E 3K7DA 3L8IA 2KK1A 1WWPA 1V4AA 1JOGA 3A4MA 3BRJA 4XEKA 1UX5A 2Q00A 1KNYA 3ADCA 2P63A 3RQEA 1O3UA 3TULA 2PBEA 3GM3A 3S9OA 3C8GB 1UX4A 1K04A 4NQFA 3IRBA 3B71A 4NNQA 1OW7A 3GM1A 4R32A 3U0CA 1K05A 2JX0A 3JYYA 1K40A 3C8GA 1PV3A 3RQFA 1WOLA 2L6HA 3RQGA 4GEHB 1OW6A 2JPUA 2LK4A 3O10A 3C18A 4XEVA 4EBJA 2YWAA 3ADDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W8I B;  3GM1 A;  3BRJ A;  4R32 A;  4XEK A;  3U3F A;  4XEF A;  3U0C A;  1K05 A;  2Q00 A;  1KNY A;  3AJM A;  2JX0 A;  1OW8 A;  1UFB A;  1O3U A;  3RQE A;  3JYY A;  1K40 A;  3L8J A;  3C8G A;  2L6G A;  1WTY A;  1PV3 A;  2L6F A;  3MFN A;  3RQF A;  3TUL A;  2PBE A;  3JZ0 A;  3C8G D;  3W8H B;  1QVX A;  1WOL A;  1ZZP A;  5F28 E;  2HSB A;  3GM3 A;  2L6H A;  3K7D A;  4EBK A;  1KTM A;  3L8I A;  3RQG A;  1OW6 A;  4GEH B;  3C8G B;  3S9O A;  2KK1 A;  2JPU A;  3GM2 A;  2LK4 A;  1WWP A;  1V4A A;  1K04 A;  3O10 A;  4NQF A;  3C18 A;  4XEV A;  4EBJ A;  3B71 A;  1JOG A;  2YWA A;  1OW7 A; 
#chains in the Genus database with same CATH topology
 1YJG A;  1Z23 A;  4JKV A;  3FOO A;  4GEH A;  4WCZ A;  1PCX A;  1T9K A;  1VOM A;  1Y4C A;  1QVX A;  3RW0 A;  1FR0 A;  1LS1 A;  4EML A;  3GAN A;  2R7S A;  4FWV A;  3QXI A;  2HJM A;  1GM5 A;  5B1B C;  5KYN A;  3RH3 A;  3KMI A;  3V7O A;  4U5G A;  4MTO A;  1HZD A;  4YT8 A;  5BQI A;  2M64 A;  1RKE B;  2I8B A;  1NSG B;  1Q51 A;  1TWG A;  1YZA A;  3QW1 A;  1BR2 A;  1RKE A;  2AWY A;  3S0X A;  4AE4 B;  3TUL A;  3AG2 C;  4YL3 A;  4CSA A;  4EWC A;  2R25 A;  3T6B A;  4MND A;  2NUP B;  1Z6A A;  1OW7 A;  4AE4 A;  1ORS C;  3HNI A;  3CEX A;  3U0C A;  1AVO B;  4RDA A;  4CS8 C;  1O5H A;  2VCB A;  1HE9 A;  1MMA A;  4MW8 A;  2NUP A;  4E17 A;  2H7V C;  3EQL F;  1A7V A;  3RSI A;  1PD0 A;  3O39 A;  1QPU A;  3NYM A;  2KW3 C;  2WL8 A;  2VCA A;  2HFI A;  3Q6N A;  3QXZ A;  2IEX A;  4U5F E;  1SZI A;  3ITF A;  4DRI B;  1ZHW A;  5T3W A;  4H4K C;  4Z9H A;  1LVK A;  3VAY A;  1WAT A;  4EBK A;  3EPV A;  3SZR A;  2QTV A;  2VX2 A;  4G7H F;  3HNK A;  4IJJ A;  2TMV P;  2A0B A;  1JXZ A;  4OIQ F;  3V5Z A;  4N4W A;  3PZK A;  4JYL A;  2MWQ A;  5L0D A;  1YA7 O;  5JP7 A;  3MFN A;  4Q7C A;  4DXW A;  4O6M A;  1ST6 A;  2J9W A;  2EIM C;  3K7D A;  3NMK A;  1U0B B;  2A68 F;  1HMO A;  5COG A;  4D4N A;  3CAX A;  1NU9 C;  3R0O A;  2R7R A;  3LAY A;  4D4X A;  3ZTZ A;  5A6B D;  4JOT A;  1F1M A;  5GPG B;  1CPQ A;  4CIP A;  1CGN A;  4LDK A;  3MYI A;  5D91 A;  1L3P A;  4U5H A;  3GM3 A;  2HMQ A;  1UX4 A;  2HS5 A;  4K0D A;  3WHN A;  4K3W A;  2J9B A;  2IXN A;  4CIH A;  2H7O A;  2XRH A;  4BEM J;  3R9T A;  5BQG A;  3SEO A;  2OJQ A;  4N6C A;  1Q0M A;  3VRC A;  2CW0 F;  5L3V A;  1DOW A;  3O10 A;  1UG7 A;  3ADD A;  1YAR O;  1D1C A;  3T88 A;  3IQT A;  1ORJ A;  3PHF 2;  2MHR A;  3S27 A;  1AEP A;  4W8P A;  3A4N A;  5DQZ A;  1LE2 A;  2IXO A;  2YZS A;  2R7X A;  5A6K A;  3TRR A;  5KYU B;  2R7V A;  2RSE B;  3NMJ A;  3NYL A;  1RMV A;  2HUJ A;  4ELW A;  5KYU A;  1LI7 A;  3EG9 B;  3W8H B;  3F46 A;  2OJE D;  3M4B A;  5B3S C;  1TWC A;  3JRM O;  4JRZ A;  3NG1 A;  1NLX A;  2F6Q A;  1WN0 A;  2HKV A;  3L1M A;  3EG9 A;  3W8H A;  2ETS A;  1H9T A;  3TQO A;  2Q00 A;  3ADC A;  3MX3 A;  3NRH A;  4QDL A;  4GYT A;  2J8W A;  4HEA J;  4I44 A;  4KC9 A;  1T6I A;  2A6H F;  3C62 A;  5A69 A;  1BDJ B;  1S7Z A;  1K04 A;  4K7B A;  4G78 A;  4W8K A;  1OCC C;  1SF8 A;  2YLD A;  4BJT A;  3G50 A;  2B0J A;  4NCQ A;  2ICW G;  3CQZ A;  2Q4F A;  3JCU Q;  2CNW D;  2LK4 A;  4JEB A;  3C8Z A;  2EJ5 A;  3KQF A;  3AGT A;  2EIL C;  2QNL A;  3AOU A;  3RYL A;  4O7G A;  5L0G A;  1WTY A;  1YA9 A;  1OCO C;  2OEX A;  3K1I A;  3ABK C;  3O4X E;  2YL1 A;  2O9X A;  1KU2 A;  2KC3 A;  2DI3 A;  3DE8 A;  3ECS A;  5JLI A;  1RJM A;  3FAP B;  3U3F A;  4XEF A;  2R7U A;  1N1C A;  1OKK D;  5BUO A;  3MYB A;  3KH2 A;  4I1M A;  2D5R B;  1S05 A;  4P9T A;  4ULW A;  3EH1 A;  3T8A A;  4OIP F;  3X2Q C;  2M4E A;  1TR2 A;  2BL2 A;  4MOU A;  4OIO F;  3RVY A;  3BEH A;  4FZW C;  2UZF A;  4I52 A;  2E87 A;  1U89 A;  2XLE A;  1APC A;  3GWL A;  4YL1 A;  3M15 A;  3V5X A;  3K1H A;  3DM5 A;  4OIR F;  1I5N A;  1B68 A;  2G3V A;  2PX0 A;  2XM4 A;  4JW1 A;  1OW6 A;  2R9R B;  3NDB B;  1CPR A;  3HNL A;  3UR3 C;  4JC7 A;  3JYH A;  1MMN A;  1LIH A;  4XQ1 A;  1NFO A;  3R2P A;  2KJG A;  4U5D E;  3NYJ A;  2DYS C;  2QY9 A;  3CZ6 A;  3TK0 A;  2JD3 A;  3UGO A;  2EPN A;  4JTC B;  1FFH A;  4CBE A;  4C3D A;  4RD9 A;  2YLG A;  3AG1 C;  2XLD A;  3DAG A;  2EPK X;  1LM3 B;  2DGJ A;  3ZQV A;  4IZD A;  3A4M A;  2ASR A;  4DBR A;  3J06 A;  4G0H A;  3KL4 A;  4HFK B;  3TD7 A;  1SMY F;  2HW5 A;  2XL6 A;  2P61 A;  4Z9J A;  2NG1 A;  3U2L A;  4N06 A;  4B6I A;  3ZC4 A;  3GM1 A;  3AG4 C;  1ZU4 A;  3B0U X;  3JYY A;  1HE1 A;  3EGX B;  4IAO A;  5JS5 A;  3K66 A;  2QLA A;  4BJ5 A;  3FVY A;  5CIV A;  3NKD A;  1A7D A;  4LAC B;  1M56 C;  3EGX A;  3OC7 A;  2FGY A;  2EIK C;  5KYX B;  5COM A;  4CJG A;  5E3A A;  4JVS A;  3U8P A;  2WVN A;  2YLI A;  3TOM A;  2VCC A;  3HTK C;  5JSL A;  2XS1 A;  1GS9 A;  1U6H A;  5KYX A;  1I4Z A;  3LS1 A;  4NTB A;  1RKC A;  1ZW2 A;  4DJ9 A;  1OCR C;  1D0X A;  1YAU O;  2KGO A;  5TJ5 E;  1M2O A;  2ZXW C;  2Y39 A;  1DOV A;  1UFB A;  3S29 A;  5FZT A;  2VB6 A;  4N6H A;  1TFK B;  1Z3I X;  3K6B A;  2OKU A;  4KNP A;  2ZPA A;  4ULV A;  3AG3 C;  4XPY A;  3LLK A;  4E7S A;  2Q9C A;  3NKE A;  3RVZ A;  4O6Y A;  5COF A;  1D0Z A;  2DYR C;  4FAP B;  3G64 A;  4DOZ A;  2P63 A;  3S84 A;  3US6 A;  4MW3 A;  4IGG A;  2UUI A;  2XLO A;  3I4U A;  4FZW A;  3C8G B;  4LDR A;  2GTR A;  2X51 A;  3RIP A;  5A6B A;  1JPN A;  5F5F A;  4MTF A;  3U9M A;  3V5Y A;  4DRJ B;  2XS8 A;  2JX0 A;  4J30 B;  4ER9 A;  4PAC A;  3C8G A;  4GQH A;  1C17 M;  4K2N A;  1FNT c;  3T89 A;  3DE9 A;  2LIG A;  4CS9 C;  2R7W A;  5L0J A;  1A7E A;  4C3B A;  1NBB A;  2P6V A;  2J9U A;  3AJM A;  1OW8 A;  2ZXO A;  3QVY A;  1OXB A;  2Y3H A;  2NSG A;  3S28 A;  4YN0 B;  1V55 C;  2WVO A;  1LS4 A;  4UDV A;  3B9Q A;  2AVK A;  1D1B A;  4OG1 A;  3W8I B;  5JT4 A;  2BE5 F;  4IRU A;  3QTH A;  4HE8 D;  3H2U A;  2A69 F;  2ZXP A;  3I5Q A;  3W8I A;  5F28 E;  2CCY A;  3L8I A;  2LCH A;  2HV7 A;  3Q7L A;  3ASN C;  1OR2 A;  3JSE O;  1JOG A;  4AK9 A;  4NY3 A;  2Q9B A;  4CDY A;  3BRJ A;  5JBX A;  2Y3D A;  2G3K A;  4CX9 A;  2LFD A;  3DMD A;  2PBE A;  4NTA A;  2PX3 A;  2L81 A;  1MND A;  4JCS A;  2LQG A;  2W4B A;  3QVZ A;  1ZYR F;  3DXJ F;  1OXK A;  2WZL A;  4A2N B;  1YDI A;  1K40 A;  1FTS A;  2NSF A;  4EUK B;  4YL0 A;  1RXQ A;  3ZTM A;  3W4Y A;  2Z15 A;  4IZB A;  3HJC A;  2XLW A;  2VH3 A;  3LS0 A;  2FAP B;  1G8X A;  5BQH A;  4PJJ A;  4ANJ A;  2LD6 A;  4IZC A;  3S90 A;  2L6F A;  5C9G A;  3TJ5 A;  1ZZP A;  5T3T A;  3GM2 A;  3H02 A;  2EPL X;  3SP1 A;  3U2M A;  3B0V C;  1EA8 A;  4MVZ A;  4KBL A;  4FES A;  4IAR A;  2IBF A;  1D0Y A;  1VYI A;  4JUR I;  4PFP A;  1YLM A;  3U3B A;  5EHH A;  3SXZ A;  1NFN A;  1V4A A;  2R7T A;  1L7C A;  4AL1 A;  1IZM A;  4XEK A;  3LNM B;  2HMZ A;  1AUE A;  2V3C C;  2OG2 A;  4U9E A;  1T6Q A;  1QKR A;  1EF8 A;  2WZF A;  2OEV A;  3N2Z B;  3Q1T A;  1ZHX A;  4WGY A;  3ZVR A;  4A4A A;  5DLJ A;  3RKO F;  3MBG A;  3O55 A;  5L3Q A;  5JUA A;  1G5Z A;  4BG0 A;  4JCH A;  2OU6 A;  3I47 A;  4BJ6 C;  3O6X A;  4CS8 A;  1VK5 A;  2HZ8 A;  1V54 C;  4G7Z F;  3SXK A;  2YL0 A;  4ELS A;  2MYS A;  4ZLD A;  1WZ8 A;  5A6A A;  4KI2 A;  3L0I A;  1J8M F;  3FMS A;  2PF4 E;  2HJ3 A;  3EJN A;  4C7O B;  3VM6 A;  3EZH A;  5L0F A;  2VC9 A;  3Q6M A;  1MJ3 A;  3JSZ A;  4C7O A;  3Q0G A;  1MNE A;  2KK1 A;  4YJW A;  3UMH A;  2W4M A;  2EPM X;  2FBM A;  2Q9A A;  1MMD A;  2QUP A;  5E2Q A;  3JT1 A;  4XWJ A;  3T6G B;  5K0I A;  1NG1 A;  4FJW D;  3P5M A;  3DM9 B;  5L0C A;  4KNV A;  4PJM A;  3B71 A;  3FHD A;  1GQA A;  2YQY A;  5DS4 A;  4RBN A;  1ORY A;  3OEO A;  3G4Z A;  2GWW A;  5T1D B;  1QSP A;  2PFD A;  3G4X A;  4OD4 A;  2X0C A;  2QQ3 A;  2AWC A;  4E0H A;  1JRA A;  1ZHY A;  2YVK A;  4OLQ A;  4NTF A;  4EKW A;  4YT2 A;  4F47 A;  1E83 A;  1E86 A;  1CGO A;  3ZG1 A;  3MYF A;  3SNH A;  1M57 C;  2L6G A;  5KYY B;  2LSE A;  4U5C E;  3QW0 A;  1ZHZ A;  3SLL A;  3HRX A;  2Q3T A;  3KYJ A;  2CYD A;  1LI5 A;  5KYY A;  1VTM P;  4ZLC A;  3GOD A;  3IPM O;  1NZE A;  1E2X A;  3U5S A;  4ELX A;  4CSA C;  4J7T A;  2V26 A;  3KYI A;  3IEE A;  2C04 A;  3F47 A;  3FOP A;  1W2W A;  1Q0K A;  3H65 A;  256B A;  4I3M A;  4JIO A;  3CSK A;  4XPX A;  4DRH B;  2YEV A;  1FMW A;  1TKN A;  4R32 A;  5KJP A;  4QIJ A;  2XM0 A;  2OCC C;  1VYK A;  1Q0G A;  2CDQ A;  2PBP A;  1Z5Z A;  1PV3 A;  4LLE A;  5HV9 A;  3B0P A;  1XWJ A;  4QI0 A;  2A0U A;  2PP4 A;  4U19 A;  4XLP F;  1VLS A;  3C18 A;  4K1O A;  3UGP A;  1DUB A;  2EPO A;  3L34 A;  3AM1 A;  1TWH A;  4U1A A;  5CI8 A;  5CI9 A;  4E7Z A;  4JEA A;  3SXM A;  1R5I D;  4YT5 A;  2PNO A;  1GGQ A;  1UIY A;  4MVU A;  2OOC A;  3JTL O;  2BC5 A;  4NEK A;  2J0X A;  4CS7 A;  3ATP A;  3E70 C;  2IYL D;  2KYH A;  2WVQ A;  3L8J A;  3ADB A;  2KSF A;  1H9G A;  5F5H A;  3H2V A;  3A11 A;  3QK8 A;  2KNH A;  2YL7 A;  2I15 A;  4IWB A;  5AC5 A;  3U9J A;  1QZX A;  1G4U S;  3AQB A;  4PFO A;  3RQE A;  3ASO C;  4X0R A;  3IHU A;  3N0T A;  2IXP A;  4U5E E;  5HSW A;  1EKY A;  4XLN F;  4JFC A;  4JWV A;  3JRT A;  1C02 A;  3LLI A;  3OWT A;  1VMA A;  3HIN A;  4U9D A;  4ZU2 A;  4WGZ A;  1JMW A;  3FDQ A;  1OR3 A;  1HY5 A;  3W2V A;  4IB4 A;  3N24 A;  2Y3G A;  3TOL A;  2ZQQ A;  3ZIB A;  2JPU A;  4EBJ A;  2XL4 A;  2PPY A;  1ZVZ A;  1NZY B;  1Q0D A;  4CDV A;  2ZQR A;  3PDM P;  4JZA A;  1PD1 A;  1YYX A;  2J7P D;  1KTM A;  3T6J A;  1NZY A;  3FDU A;  4MS2 A;  4G7O F;  4MI2 A;  3VYW A;  4AX2 A;  2GAQ A;  1Z7Q c;  1QLE C;  4NC3 A;  2R02 A;  2P7V A;  2AP3 A;  1LE4 A;  1O87 A;  3EZI A;  3LES A;  4QI2 A;  2XL8 A;  1ZU5 A;  5AGF A;  1SR2 A;  1O3U A;  1TWA A;  1ZHT A;  3ABL C;  1DCI A;  4M63 A;  4Z9I A;  3WAQ A;  2A6E F;  4J32 B;  4NQF A;  1T5O A;  2C03 A;  2XSE A;  1K05 A;  1EY3 A;  2XLH A;  2AU5 A;  3K1I C;  2P0N A;  3Q7G A;  5KYW B;  4MVO A;  2L6H A;  3R7C A;  4EBB A;  1BBH A;  2W45 A;  4I4Z A;  4JE9 A;  4LDQ A;  5E33 A;  4EIY A;  3QZC A;  3EH2 A;  2P1A A;  2F22 A;  1BR1 A;  1FFT C;  4XPW A;  1R4T A;  5KYW A;  3ABM C;  3M1C B;  1ZW3 A;  2L7A A;  3POV A;  3DZA A;  5D92 A;  1JR8 A;  2XXA B;  3DJU B;  4P9F A;  1XZP A;  3C8G D;  5A6J A;  4XTK A;  2CNW A;  4AL0 A;  1OCZ C;  2GFH A;  2XXA A;  5B1A C;  4P6I C;  2YRF A;  3HNJ A;  2RD9 A;  1Q0F A;  1G4W R;  1RJ9 B;  4H54 A;  3IQC A;  4YK5 A;  4FX5 A;  1WGW A;  3GWN A;  3LEV A;  2EIN C;  3U8V A;  1HMD A;  3RF3 A;  1T6U A;  2J46 A;  3H81 A;  2EIJ C;  2HSQ A;  1RJ9 A;  4JCZ A;  2DB4 A;  1OKK A;  2H8A A;  5AC4 A;  4IAQ A;  1C03 A;  4L6R A;  2WB7 A;  4Q4Z F;  1NU7 D;  1A0B A;  3OA1 A;  3WG7 C;  3GEI A;  3T4R A;  3UMK A;  4KNW A;  2Y3B A;  2B0H A;  4JTA B;  2J9V A;  4DVZ A;  1I4Y A;  3ZDL A;  1EQ1 A;  1V74 B;  1T01 A;  3B29 A;  1MMG A;  3HLZ A;  1BR4 A;  1Y64 B;  4J7Y A;  4CS9 A;  1BZ4 A;  1FAP B;  3ZSU A;  4O79 A;  1VB5 A;  1IW7 F;  2R03 A;  3PMR A;  3FXH A;  4I42 A;  2IXM A;  1Z63 A;  2J45 A;  2LFF A;  4O6N A;  5E3C A;  3SXY A;  2HV6 A;  2A1D D;  2VAS A;  4MVR A;  4BEJ A;  1WAS A;  3M79 A;  1YYJ A;  4MQ9 F;  4OD5 A;  2GA0 A;  3HKK A;  1EF9 A;  4BJ5 C;  4JJF A;  3S9O A;  3A9C A;  3UMI A;  5L0H A;  1JAF A;  3IRB A;  2Y69 C;  1MQV A;  2XLM A;  4EHP A;  2QE9 A;  3FAJ A;  4MVM A;  1M2V B;  5IY5 C;  2GDC A;  5JRA A;  2R7O A;  1Q52 A;  2NUT B;  4PR9 A;  5DS6 A;  3X1O A;  4I1O B;  4XEV A;  5DS5 A;  1M2V A;  5FCL A;  3EFO B;  2VRE A;  1LPE A;  2NUT A;  3LNR A;  3DWW A;  5EK0 A;  2DUB A;  2WZG A;  3EGD B;  1QQ3 A;  4JJG A;  3KPH A;  2HSB A;  2OQM A;  3EFO A;  3M4C A;  3EGD A;  2J0W A;  5DVW A;  3WOD F;  4F4B A;  1CGM E;  4C3E A;  1H6G A;  4HFF B;  1JPJ A;  3NMI A;  2IOQ A;  3LEO A;  1M6T A;  3DI5 A;  2R05 A;  3A4L A;  3QMK A;  1OQC A;  1WWP A;  3AGU A;  3MLG A;  2W9Y A;  2FFH A;  3E9V A;  1RCP A;  3AQC A;  4YT4 A;  4LER A;  1LKX A;  4WJ0 A;  2YHS A;  4E0I A;  5JBW A;  4JTD B;  1A41 A;  1KNY A;  3LUT B;  2R7Q A;  3MOY A;  3KKB A;  4MVS A;  3I5P A;  2D4U A;  3R9S A;  2L9J A;  2LP4 A;  1E84 A;  1VLT A;  1XZQ A;  1YVI A;  1YZC A;  5L0I A;  4MTG A;  4U18 A;  2NPU A;  4PJN A;  1E85 A;  2G62 A;  3IQ5 A;  3PCV A;  4BJ1 A;  3DAF A;  3IQ6 A;  4BPM A;  1D1A A;  4U5B E;  4CJO A;  4MVQ A;  1Y6D A;  3RQG A;  3TLF A;  3GEH A;  3DD7 A;  1HW1 A;  4ONS A;  3UNG C;  3TJ6 A;  1J8Y F;  4Q5S F;  3T9O A;  4CDA A;  5EGY A;  1HW2 A;  3RFY A;  5DQT A;  3GEE A;  2ZD9 A;  3JZ0 A;  4WAB A;  1RJN A;  4PK4 A;  1SYQ A;  2FW2 A;  3K33 A;  4DBQ A;  2YKZ A;  2ZXR A;  4E18 A;  3C7J A;  1H7I A;  3EHN A;  3EHM A;  4BJ6 A;  2J7P A;  1EI7 A;  2H7B A;  2IM8 A;  3W2W A;  3GOR A;  4PJL A;  3VF0 A;  1TFO B;  2XLV A;  3DJN B;  3Q0J A;  1UX5 A;  4DVY P;  3ZWI A;  4LLC A;  2CGE A;  5JVE A;  3ZQY A;  3C63 A;  3LJB A;  4YWQ A;  2KQ9 A;  5B3I A;  4NNQ A;  2Q7R A;  4QII A;  1TQG A;  3SWX A;  1FMV A;  2UUH A;  3RQF A;  4OIN F;  3DKA A;  1WOL A;  4GEH B;  3SYN A;  2YL3 A;  2YWA A; 
#chains in the Genus database with same CATH homology
 3AJM A;  1OW8 A;  3A4N A;  3AM1 A;  2L6G A;  1WTY A;  2L6F A;  3JZ0 A;  3O4X E;  1QVX A;  1ZZP A;  2HSB A;  4EBK A;  1KTM A;  3GM2 A;  1RJM A;  1Y64 B;  3W8I B;  3U3F A;  4XEF A;  1UFB A;  3L8J A;  3ADB A;  3MFN A;  3C8G D;  3W8H B;  3A4L A;  5F28 E;  3K7D A;  3L8I A;  2KK1 A;  1WWP A;  1V4A A;  1JOG A;  3A4M A;  3BRJ A;  4XEK A;  1UX5 A;  2Q00 A;  1KNY A;  3ADC A;  2P63 A;  3RQE A;  1O3U A;  3TUL A;  2PBE A;  3GM3 A;  3S9O A;  3C8G B;  1UX4 A;  1K04 A;  4NQF A;  3IRB A;  3B71 A;  4NNQ A;  1OW7 A;  3GM1 A;  4R32 A;  3U0C A;  1K05 A;  2JX0 A;  3JYY A;  1K40 A;  3C8G A;  1PV3 A;  3RQF A;  1WOL A;  2L6H A;  3RQG A;  4GEH B;  1OW6 A;  2JPU A;  2LK4 A;  3O10 A;  3C18 A;  4XEV A;  4EBJ A;  2YWA A;  3ADD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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