The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
96
|
sequence length |
316
|
structure length |
307
|
Chain Sequence |
MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVVAIDAGYRHIDCAYVYQNEHEVGEAIQEIQEKAVKREDLFIVSKLWPTFFERPLVRKAFETLKDLKLSYLDVYLIHWPQGFKSGDDLFPRDDKGNAIGGKATFLDAWEAMEELVDEGLVALGVSNFSHFQIEKLLNKPGLYKPVTNQVECHPYLTQEKLIQYCHSGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHTAAQVLIRFHIQRNVIVIPSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNLLQSSHLEDYPFNAEY
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule keywords |
Aldo-keto reductase family 1 member B10
|
| publication title |
IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors.
pubmed doi rcsb |
| source organism |
Homo sapiens
|
| molecule tags |
Oxidoreductase
|
| total genus |
96
|
| structure length |
307
|
| sequence length |
316
|
| ec nomenclature |
ec
1.1.1.300: NADP-retinol dehydrogenase. |
| pdb deposition date | 2016-07-15 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| X | PF00248 | Aldo_ket_red | Aldo/keto reductase family |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Barrel | TIM Barrel | NADP-dependent oxidoreductase domain |
