The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
130
|
sequence length |
372
|
structure length |
361
|
Chain Sequence |
HASAIESIETIIVDLPTINQTLVLIRLRCADGIEGLGESTTIGGLAYGNESPDSIKTNIDRFVAPLLIGQDASNINAAMLRLEQSIRGNTFAKSGIESALLDAQGKRLGLPVSELLGGRVRDALPVAWTLASGDTAKDIAEAQKMLDLRRHRIFKLKIGAGEVDRDLAHVIAIKKALGDSASVRVDVNQAWDEAVALRACRILGGNGIDLIEQPISRNNRAGMVRLNASSPAPIMADESIECVEDAFNLAREGAASVFALKIAKNGGPRATLRTAAIAEAAGIGLYGGTMLEGGIGTLASAHAFLTLNKLSWDTELFGPLLLTEDILAEPPVYRDFHLHVSKAPGLGLSLDEERLAFFRRE
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Isomerase
|
| source organism |
Pseudomonas fluorescens
|
| publication title |
Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes.
pubmed doi rcsb |
| molecule keywords |
Muconate cycloisomerase
|
| total genus |
130
|
| structure length |
361
|
| sequence length |
372
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
5.5.1.1: Muconate cycloisomerase. |
| pdb deposition date | 2008-04-11 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02746 | MR_MLE_N | Mandelate racemase / muconate lactonizing enzyme, N-terminal domain |
| A | PF13378 | MR_MLE_C | Enolase C-terminal domain-like |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Enolase-like C-terminal domain | ||
| Alpha Beta | 2-Layer Sandwich | Enolase-like; domain 1 | Enolase-like, N-terminal domain |
