The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
104
|
sequence length |
429
|
structure length |
414
|
Chain Sequence |
MKLDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFLQEVLDYLTNSASLQMKSPAITATNRTLYLQSVTSIEERTRPLSKGLVDGQELAVADVTTPQTVLFK
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.
pubmed doi rcsb |
| source organism |
Homo sapiens
|
| molecule tags |
Cell cycle, ligase
|
| molecule keywords |
amyloid protein-binding protein 1
|
| total genus |
104
|
| structure length |
414
|
| sequence length |
429
|
| chains with identical sequence |
D
|
| ec nomenclature | |
| pdb deposition date | 2004-06-21 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| B | PF00899 | ThiF | ThiF family |
| B | PF08825 | E2_bind | E2 binding domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Ubiquitin activating enzymes (Uba3). Chain: B, domain 2 | ||
| Alpha Beta | Roll | Ubiquitin-like (UB roll) | NEDD8-activating enzyme E1, catalytic subunit | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain |
