4J6IA

Discovery of thiazolobenzoxepin pi3-kinase inhibitors that spare the pi3-kinase beta isoform
Total Genus 264
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
264
sequence length
945
structure length
833
Chain Sequence
MSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEECDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCLLYYVNLLLIDHRFLLRRGEYVLHMWQISGFNADKLTSATNPDKENSMSISILLDNHPIAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHIERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
molecule keywords Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic sub
total genus 264
structure length 833
sequence length 945
ec nomenclature ec 2.7.1.153: Phosphatidylinositol-4,5-bisphosphate 3-kinase.
pdb deposition date 2013-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00454 PI3_PI4_kinase Phosphatidylinositol 3- and 4-kinase
A PF00613 PI3Ka Phosphoinositide 3-kinase family, accessory domain (PIK domain)
A PF00792 PI3K_C2 Phosphoinositide 3-kinase C2
A PF00794 PI3K_rbd PI3-kinase family, ras-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1070.11 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 Phosphatidylinositol 3-/4-kinase, catalytic domain 4j6iA05
1.25.40.70 Mainly Alpha Alpha Horseshoe Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat 4j6iA03
2.60.40.150 Mainly Beta Sandwich Immunoglobulin-like C2 domain 4j6iA02
3.10.20.90 Alpha Beta Roll Ubiquitin-like (UB roll) Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 4j6iA01
3.30.1010.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 4j6iA04
3QAQA 1S3SG 1WR1A 2B3AA 4KVGB 4WEEA 4EFOA 2NQ3A 2K25A 1WGDA 3QQ8B 4BOSC 1WX7A 4BFRA 2K8MA 1WM2A 3ZNHB 2ZPNA 4GDKB 1G6JA 4PS3A 2DZJA 1V5TA 4TKNA 2BYFA 2ZPYA 2UZPA 2CJSA 2JVCA 3VH4B 4K7WA 2L76A 3R66C 4WWNA 4P7IA 3SDLC 1WX8A 2DZMA 4KIKA 2MA9B 4RM9A 1IP9A 1WE7A 1Q0WB 4IM2A 3ZRFA 4NY0A 3TWYA 4AJWA 2LASA 2XK5B 4BOZB 2WXOA 4F93B 2JZ3B 2D8KA 2WXHA 3QC8B 3NY5A 3HIZA 4ICVA 4XC2A 2EP6A 2ZVNA 3JW0X 2FAZA 3DDCB 3EFUA 1UOVA 4EZKA 1P9DU 1R4NI 1WMHB 2KNBA 4MSQB 4X57B 4HK2A 1UH6A 4ANVA 1WE6A 1WXMA 2NVUI 3ZDTA 2ZZPB 2MBOA 4AUQC 4ICXA 1QATA 2R2QA 5D6JB 3IBEA 4GU2A 3ZO5B 3AU4A 1H4RA 2KKCA 5C1ZA 2LWPA 1WGRA 1IYFA 1PQSA 4PS7A 1OQYA 4G11A 4XX5A 3KH0A 3L13A 2L3ZA 1YX6B 2D3GA 3NZSA 4JLCA 3VXWA 2WXMA 3VUYA 1IPGA 2A5UA 3L17A 4TS6A 2BPSA 4IWPA 3DBLI 4NP9A 3KUZA 4BVUC 2L00B 4MGKE 4DHZB 4ZDVA 5DPWA 2IBIB 3HM3A 1GNUA 5AZFA 5CCJA 2EKEC 1LXDA 2V4LA 1BDYA 4GDLB 1V9JA 3L9BA 1UZXB 3MHSD 2KMCA 3V6CB 3H7SA 3A9KB 3OJ3A 3UGBB 4AJYB 1Q1OA 1C1YB 1V27A 1KM7A 3ZIMA 1H8CA 1Z2MA 3IM1A 4ANWA 4W9GA 1YD8U 2ZNVC 4DHZE 4V11A 1WRDB 1EF1A 2O6VA 3LS8A 4QAMB 2JY6A 2Z0EB 2PE9A 3DOWA 4GMVA 5IA7A 2N7DA 4ANUA 4AP4C 4UWLA 4GIVA 4WAAA 2KHWB 2CS4A 2KC2A 1WZ3A 4M0WB 4ZRJA 3L16A 2DYMA 4MGIE 4EZLA 1EF5A 2MLBA 3DBRI 4JIOU 4RM8A 5LLIA 2JQZA 3ZNID 1RLFA 2DZKA 2KJHB 1S1QB 4YL8A 2IO2B 3B1LX 1GJZA 3TJPA 4W9DA 1J0GA 2L0TA 2RPQA 3B7YA 3Q3JA 4LDTD 2WXPA 4UWFA 2CR5A 3QCAA 2ISDA 3PGEA 3PVLA 4OVUA 1LFDA 2GOWA 4M8NA 3RDJA 5D2MB 3WAMA 4KSLC 3RZWC 3JYUA 4HCPB 1W16A 3PT2B 3W1SC 2WXGA 2K8HA 2UWQA 3NS8A 4G3XB 3M3JA 1RH8A 3L10B 2KD0A 1E8ZA 4IW0A 2CHWA 2NBVB 4M8MA 4Y1TA 2PE6B 3JVZX 1E90A 2C7HA 1Y8RC 4WJQA 4GXBA 3UQBA 2R2OA 3PSEB 3RPBA 2JUOA 3DVNU 4K7SA 2X6HA 2ZVOA 3QARA 4TV3A 1OTRB 2X6IA 2CM6A 2ZKMX 1YJ1A 2MRPA 4K1RB 2VRRB 3QA8A 1WY8A 2RR9A 3IFWB 4IM3A 2KTRB 1CJYA 5D94A 2C7MB 3V6EB 1I42A 4GOCA 4ZRKA 2OJRA 2X6FA 2FCQA 2D11A 4HLEA 2FCSA 3T9LA 2L7RA 3JSVA 4IC7B 2NCEA 4LDCA 1GC6A 2DMGA 1WH3A 2XEWA 4LJOB 2WX1A 3MJWA 2LHAA 5FR6A 2KJ6A 3WIMA 3APCA 4HWIB 3NHEB 2FNJB 4F7ZA 5EDSA 1XT9B 4NS0A 4K7UA 4UWKA 5G2NA 3ECIA 4EEWA 4HVBA 3O65B 3RUIB 3TMPB 5CHVC 4FJZA 2K3HA 3PRMB 3B0AA 2KDIA 4NQLB 4L2YA 4AWJA 4E71A 3V61A 2RGFA 2K4AA 4IUMB 1E8XA 2QZQA 5TR5A 4II3B 5JZEB 4NPJA 2D07B 4BGDA 2DAJA 4I6NB 1WGHA 3JSVB 3X0WA 4NAWA 2CHZA 2NBWB 3PLUA 3EECA 3KUCB 4FJVB 4GDKA 1WFYA 2WDTB 4JPSA 3W1YA 3F04A 4URKA 2M1MA 3KWTA 2KQSA 2KTRA 3VH3B 4GN1A 1A25A 1M94A 3F01A 2AYOB 2L05A 3IG3A 4JL9A 5GMVA 2WXLA 3UQAA 5E6PA 3VQIA 2RSUA 2MCNB 2O2VA 3L0WB 1TZ1A 3VAWA 4L1LA 4NNJB 1OEYA 5H4YA 1V80A 3CSTA 4KDIC 3EC8A 1V2YA 2MSED 4WJPA 4B95A 3PRZA 4W9CA 2PEAA 1WGYA 5ANLA 4EUTA 2N9PC 5LXIB 3H7PB 3WAPA 2KANA 1WFJA 2N4FA 1WJUA 4MGZE 2Z59B 3X23A 2JF5A 4FULA 4LT7A 2DMHA 2KFKA 3HK0A 3RZFA 2LRWA 3LJ3A 4DXAB 2KI6A 5E6NA 2FIDA 2CHDA 5CCGE 2ENJA 3ALBA 3PZDA 1WFMA 3VFKA 3PV1A 4ANXA 4L1BA 4ICWA 3Q3FA 3M95A 3ML9A 2IY0B 4WWPA 4WAFA 4QJ5B 4IHBA 1DJWA 2KFKB 2O2VB 1LQBA 2EMTA 1V5OA 2FK9A 4CYEA 2WXJA 3GPEA 3OHMB 1BCIA 5HKHA 2LZ6A 3W1SA 3SU8X 2OOBB 5J17A 1TGZB 1WI0A 2G4DB 3N30A 2N1VA 3VTVA 4FLHA 2L8JA 2BWQA 3NSJA 3PTFC 4MEMA 1HE8A 1XD3B 4TQ0A 1L2NA 4E74A 5CCHE 3R7QA 4GNKB 2ENPA 3CMMB 3GOEA 3ZDMC 1AARA 5D7GA 4DWFA 2N9EB 4WWOA 2N1TE 4HPLB 4KIKB 4W9FA 4DDGD 4NPNA 4FHJA 1T0YA 2BF8B 4FA6A 2DX5B 3KYCD 1BYNA 1GC7A 2BYEA 1MG8A 1KOTA 2KDEB 2FCMA 1A5RA 3ZTDA 2NBUA 2LJ5A 4W9KA 5IAAC 3SD5A 2CU1A 4MSMB 5DPRA 3V62A 1U4AA 3OLMD 4MM3A 1WM3A 4K81A 3A9KA 3TIXA 5L83A 4B9KA 3I3TB 3MTNB 1F9JA 4GDLA 2KMAA 3APDA 4WJOA 4ICUA 2BWFA 2J7QB 2ZJDA 4FHKA 2DAFA 4HDOA 2WXQA 2G3QB 2HJ8A 3IHYA 3T8MA 2PJHA 4W9EA 2O6VB 4LDTB 2FIFA 4A20A 3A4SC 4IWOA 2IO3B 2CJTA 2FCNA 4TUUA 5JH5C 3P2BA 2LVPA 2LXCA 1WIAA 2NCNA 3C0RB 2GBRA 2WXKA 1SIFA 2LUEA 3DVGX 4A3OA 2KWUB 1RAXA 1SE9A 1CJAA 1UGMA 1UD7A 1TTNA 4LCDE 2A4ZA 1WZ0A 2YRBA 3A9JA 2IO0B 3W57A 3HM6X 1DJGA 1KJTA 4IWQA 4EKUA 2PPHA 1D3ZA 2M4NA 2JRIB 1YIWA 4HJKA 2J0JA 2AL6A 1LM8B 3H1UA 4LJPB 2LGYA 1UOWA 2LRUA 3F05A 1SGHA 4HXDA 1DJXA 1GG3A 5CX3A 5KHOA 3V60A 1ISNA 3KWUA 5DPSA 1DJIA 1K8RB 4HDQA 3D32A 3W56A 3EHVA 1WJNA 3DVNV 3U8ZA 3VUWA 1J8CA 3PS6A 5LXHA 3U7DA 1R4MI 1UELA 4MJJA 2JPHA 3AULA 2BKRB 4NJ6A 2NSQA 1TJXA 2K1FA 1RFAA 2MX2A 2J0KA 2MBEA 2MBQA 2MP2B 3QX1A 2V1YA 3WANA 4F91B 3AXCA 1BT0A 1P3QU 2IYDB 1WJ6A 1ZW7A 4KSKC 3ZNZB 2KC1A 2KLCA 3N3KB 4GSWA 5E6OA 1VCBA 3QWZB 3TBLD 1NDDA 1C3TA 3N5AA 3A9JB 4KV2A 5JHAA 4NJ7A 3TL5A 4FADA 4F8CB 5CTRC 2AWTA 2WXIA 2KDFB 4DNLA 3KW5B 2EMSA 3VTWA 2BYVE 2LGDA 2DHZA 2KQ7A 3IHPC 1X1MA 2UYZB 3A33B 4MELA 1XQQA 2AL3A 2LGXA 1WF9A 3WAOA 4OVVA 3L4CA 2BGFA 4JQWC 4BKSD 1UGKA 3DQVA 3DBSA 3WA0A 4BBNC 3GZNI 3CSFA 1P98A 2GMIC 3A4RA 4UWGA 1YRKA 2KOXA 4L23A 2WX0A 1GUAB 2X6JA 4OYSA 4A3PA 2ZCBA 2M8SA 4ZYNA 3ZVVA 2N1WA 4IM0A 2D2QA 2N9XA 4J6IA 3S2AA 4XE0A 1ZGUB 4UWHA 4I6LB 2NR2A 1DJZA 3PYCA 1L7YA 2JT4B 2NPTB 3HN8A 3ZUNA 5L95C 3ZTCA 2Y3AA 3PHWB 3N32A 2Q3XA 3ZNGC 1DJHA 2JZZA 2D10A 2JRHA 2CKHB 2JWZA 2BKFA 2Q0ZX 2W9NA 3DBHI 3M62B 2KFJA 4KITB 1VD2A 4F92B 2K39A 5CHWA 2KVRA 5ENNA 1J19A 1TBEA 3DPDA 2GBNA 4CO7A 2DENB 3WALA 3SHQA 4PS8A 2DZIA 3RD2A 3PRPB 1UBQA 3KYDD 1DSYA 2C5LC 3L08A 2Z0UA 1NI2A 2LI5A 5AZGA 5C23A 4LCVA 5JHBA 2I1KA 1FXTB 4NPKA 3UIPB 3QR0A 4WQOB 3H6NA 2NPTA 2KDBA 2XBBC 3M63B 4BKGA 4DBGA 4GGQA 3L54A 1EUVB 1WXAA 4EZJA 4IQHA 3H7PA 2C60A 1QASA 3VVWB 3RULA 5AEKB 3VUXA 4ZRIA 2L0FA 3A1QB 4Y1SA 2K6DB 3OAWA 3FBKA 2MBBB 3HHMA 2YVCA 3TCAA 1V86A 4B6WA 4CHKA 1WXVA 2FUHB 3VDZA 2O6VD 3BY4B 1E7UA 2X38A 2RD0A 3QJZA 2MQJA 2WYQA 1Z5SB 3UF8A 2MBHA 4BKSA 3RYTA 2IY1B 4W9HA 4WJNA 2X6KA 2BWES 1RSYA 3ZW3A 4FJYA 2V3SA 4II2B 4G0NB 3R7RA 1GMIA 2HTHA 2KXJA 2KZRA 2G45B 2YOAA 2QZ5A 2R83A 2B3RA 1P0RA 4HPMB 1WX9A 4ASWC 4QJ3B 2K8CA 4N9F4 5DCNA 4DHJD 1WXSA 4IG7B 3QR1A 4NQKE 4EOYA 3VHTC 2AEHA 2FJUB 1DJYA 3QHTA 3RCZA 3QK0A 3RT3B 2G4SA 3K9PB 2M0XA 3PLVA 3QIJA 1RRBA 4HCNB 1TJMA 5H4ZA 1V6EA 2I1JA 3K9OB 1NBFC 4GB9A 2ENQA 2C9WB 3UIOB 3F00A 2KLGA 1V81A 2ASQA 1DQVA 1WJ4A 4PH4B 4AOFA 3R3MA 2HD5B 4G50A 5KJ7E 4KDLB 4BKTA 5J18A 1K5WA 1UBIA 2MWSB 4KZ0A 2M17A 3PPAA 4I6PA 1E8WA 2J0MA 3PREA 3DCGA 4A55A 1OEYJ 2QHOA 1JRUA 3PHXB 4PYZA 5T8IA 2KK8A 3A1QA 3M7FB 2LXAA 5AZHA 2KWVB 2GBMA 2KO3A 2KTFA 2NS5A 3FDWA 3AI5A 5CHFA 1W15A 2K8BA 5DPTA 5BO4B 2HE7A 4MJSA 2Z0DB 1ZKHA 4DHJB 4MDKE 2LD9A 2YLMA 4E3CA 1WYWB 3JZYA 3OJ4B 1QZEA 2GBKA 2MP2A 3KUDB 4BBNF 1WGGA 1KLVA 3CF6E 2ZNVB 2K45A 2LVQA 1WMHA 1RLWA 2WXFA 2CHXA 3DVGY 4XZ4A 2ZEQA 4RMAA 2IZVB 4DK5A 1P1AA 4JGHB 2JXXA 3ZRCA 2IO1B 1WR6E 4FBJB 4QJ4B 4PYUA 1V49A 3IVFA 2ZCCA 3ENEA 2KX3A 3AU5A 2KWCA 3ML8A 1EO6A 3ZLZA 2DYBA 2CM5A 1YX5B 1Q5WB 3KVFB 4TQ1A 2WXRA 5J2RA 4F1SA 2REXA 4DDID 2KJRA 4MGYE 1OGWA 2N7EA 2MW5A 3APFA 2KN5A 3H9DA 3NOBA 3UINB 1YQBA 2DYOA 2LVOA 3B08A 2XK5A 4NAWB 3VTUA 4MJSB 3PFQA 1E7VA 1E5WA 2K6QA 4MH0E 4W9LA 3ZKJC 3BINA 5G55A 2GBJA 1I35A 3U30A 2KX0A 2I9CA 2WWZA 2WXNA 4KZCA 3ONSA 2Y5BB 4W9JA 4W9IA 2C7NB 4FN2A 5KHQA 3LDZE 1E8YA 1CMXB 3NZUA
chains in the Genus database with same CATH superfamily
2EUZA 5HDRA 5JA4D 2X6BA 4WEMB 1S3SG 2DM7A 2FT7A 3FU9A 3L2LA 3ZL1A 1KN2H 3BN9C 4K94H 1P7QB 4L3CB 3UZEC 1WX7A 4BZ1L 5IQ7H 3ZNHB 3QXDB 1UUPA 2HRLA 3O3EB 1N6VA 2OOEA 1FAIL 2QHRL 4JHBA 3SE6A 2Y69E 4AQ7A 2DZMA 4DT2A 3RKVA 4H13C 4X5QA 3U9PL 5JIIA 1E6EB 1Q0WB 1QHQA 2YAEA 3KS2A 3U0TB 4X7CC 4CMHB 4YZFE 4O2FB 5LX8A 1E4KA 1UKQA 4MNGB 4F93B 1FDLH 3NY5A 2YFNA 2G9KA 1HL9A 2QADC 3KL5A 3O9WB 4LKXB 5MEPB 1ONQB 4J4PC 2W0FB 1UOVA 3E7JA 5KOVC 3U46B 5BZXA 4PWFA 4HC1L 4RG9A 1MLCB 1NUGA 1RFKA 1T21B 4QRAA 5CJXA 5FXCH 3VI3F 2Y36L 5EU4A 2MBOA 2P58C 2BVQA 4Z8FL 1G6RH 1QSFA 4KXDA 3OKLA 2CRIA 1KWKA 3HS0B 5E23A 2ZUUA 3PAYA 1RZJL 1UJKA 3BGMB 1B6UA 3OSVA 4Y88A 4FL4C 4GAYA 5F6HI 1FCCC 4K3CA 4OUUA 1NJ9B 4M6AA 1W72A 3UC0L 1CMOA 1QQDB 1R47A 2BPSA 1NPNA 3HS0A 3NG5A 4LP8A 2N9LA 1H6TA 2R61A 2OR9H 4D9QE 1S8DB 4NUGL 4GXVH 3DUUA 4RCAA 3IDMA 5DZJA 2UV3A 1EPFA 1FRGL 2ZSWB 3ATFA 3TFBA 1GNUA 1X6LA 2ESVD 3C5JA 4GDLB 1BDYA 4MGXA 4XMUA 5MPOA 2BJML 3S7GA 1VZ8A 4I2XA 4JM2F 3G5ZA 3OV6A 1UC6A 1CGYA 4HCRH 4Y16A 3KLDA 3TEZA 5I6XC 2PE9A 5DHXB 2OX5B 1NQBA 4YTMB 2KERA 3H6AA 1G7PA 2QQKH 2KHWB 2CS4A 1U8IA 4QD2E 4APQD 2F19L 2FIRT 3FHAA 4JIOU 1G1YA 2ZCLH 5J0BA 5D1QA 5GQBA 2P5PA 3B1LX 1DL7H 4OKVA 4OLUL 4XZUA 3KEDA 5DJCB 1OLZA 1JUQA 3KPMB 3NK4A 4J8QA 4UIKH 3UGXA 3L9YA 5F0PB 3SKJH 2J4DA 3P3YA 4DKEH 2GI9A 2X12A 4KMOA 5F7EH 4QHLB 4LKCB 1Q0EA 3IVKB 4XO3A 3KHQA 3L10B 2KD0A 4PIRF 3ULVL 2NBVB 3OKMA 2GJJA 1OE3A 1T7YA 2XY2A 3CZNA 1NC4B 2XQBL 3QPXH 5TK2A 5GRVL 4XNMA 4WNFA 4TUKL 4PRHB 4U49A 3ARGD 2NMQA 4S11A 4I3GA 2X44D 4J0UA 2J72A 3DX3A 2VRRB 5B38A 3IFWB 3IXTB 2OMYB 4L3FA 4YXLL 2HP4A 1HINH 3BYTA 1K4CB 4N8CH 3STZB 2L7RA 2NCEA 1NDTA 5DJZB 2QSDA 4L3ED 1SPDA 2NUTA 5J1SC 2XVKA 1I7TB 1QSEA 2NQDA 1G7IA 2N0KA 1UH2A 1OCCB 4AYFB 4QTIL 4PLKC 3B9KC 4BGLA 3PP3K 1OM3L 2C9UA 2RH0A 4MB5A 5F6HJ 5J3HC 1U8JB 4JY6A 1XR8B 4EI5B 2HKHH 4E71A 4DVRL 4EI6B 1RZIA 2RGFA 1NICA 2J44A 1H3XA 1IX2A 1E8XA 2QMJA 2WTRA 2ZWLT 2QZQA 4KROC 1QUPA 1NBVH 1M53A 1NA0A 3KLHD 3QUYC 4LQ1A 4NI6A 2J6EH 1V3KA 2YRLA 4LU5H 3KUCB 4FJVB 4IRUA 4PBWD 3MX3A 2CDEB 4EBQL 1SW6A 3V0FA 2GVYA 4URKA 4PCKA 1QSVA 2X40A 3TWVA 4B8AA 1TJHL 1IUZA 4JFEA 2WBXA 3ZXRA 2CXKA 5TF1L 3GSWB 3IGAB 3C3OA 5C1DA 3MNMA 5KANG 2VZKB 1F90L 4AG4L 2VDMH 3KJ4C 4HJTA 4OFPA 2GUOB 1S5HB 4EIBA 4NZTH 1X5HA 5JQ6L 3FO1B 3NRPA 2VTBB 3IXAA 4KC3B 1JRHH 4ZXBD 4DAGH 2HFEA 4DGVL 5IMOB 4EEEA 3WFBL 4CAGA 1BF5A 1QD0A 3PZ4A 2HO1A 3D39E 4XMPL 3T65A 2DYSB 1QSED 4A2LA 1PAZA 1PGAA 4PLJC 4X4YB 2QQLL 1JGEA 2E9BA 1PDKA 3UTPE 2IOOA 3ARFD 4FZ8L 1F3JA 5GHWH 3TWQA 1I1AB 4XVTL 1S9YB 3EDDA 5E5UB 4XH2B 2O2VB 3T65B 4NWTL 2FK9A 3QB2A 1MJ8H 2JQRB 3RVWD 4ARIA 2R39A 1OARH 4U0UA 4D3CH 1ZLVK 2BVTA 2M19A 4KPHH 4LNRB 5LKNA 2W1NA 5D70H 1RPUA 3X2QB 4OI9A 1AI1H 1MHPH 1T5XB 2YC1B 3PQYD 3WTSA 3V4LA 2L8JA 3EBIA 4PRDA 4ZS6C 3LKOB 5I1EL 4ZMTA 4HKZA 1XD3B 2D3BA 1KDJA 3CMMB 4JFOB 3EUUA 3TVMD 3BISA 1ITBB 2VUOA 3NVQA 1U8NA 3TZVD 4K7FB 5J11C 3F5WB 3H8HA 2AVPA 25C8L 3L95A 1IEHA 1AQMA 3KJ6H 4LSPH 3RNKB 2GG1A 4ILDA 2NBUA 1XF5A 1AC0A 2XKSA 4QF1B 3SD5A 1Q0YH 4Q58C 3IFOB 4AUUA 4D0DB 3MRJB 2ZW0A 3NIGB 4JHRA 2VMJA 4UNVA 4OV5B 1RULH 1A1MB 4WNSA 3VFRA 5AUMB 2N4IA 2XZQH 3MNZA 4JRLA 1OTUC 4GDLA 4YSYB 1I1AC 3QFJA 3CMGA 1AXTL 4UAOB 4CC4A 3E3QC 4FHKA 3L2MA 4HDOA 2OL3A 1IT9L 1L7IH 1MXDA 3LZNA 4YBQC 5E2UL 2A77H 2HJ8A 1WM5A 4CKQA 4FLQA 1URLA 1S7RB 4AC2A 2LXMA 1M2VB 1V8HA 1Z7JA 3VRIA 2PVOD 4G8GE 1OANA 3ULUD 1LMKA 3P2BA 4JFFD 3AE8B 3U0PA 1Q94A 4PWHA 4N1HB 2GBRA 1HL5A 4PJIA 4N2NA 3KM1A 3NCYP 2RALA 2KWUB 1NCCH 4MMXA 3VXPB 5LCWC 1J1XL 4IMLB 4YFDB 3RWIA 2CJNA 1Y1UA 2EH8L 1TS2A 1BJ1J 3AG2E 3FQWB 4ZD3H 3L5HA 3NSYA 4NUPA 5ETUB 5I71B 2PPHA 2M4NA 2G5BA 1WFUA 4FTDA 4IJ3B 2MA9B 4HJKA 3HPLB 1YOVB 1GYUA 2Y0BG 1KYOK 3NRQA 4KK8C 1KBKA 4MTMA 2J55A 3FTYA 4WUKH 1KCVL 4HPYL 3OKYA 4L8BB 4CJ1A 1ISNA 3U8ZA 3MGOA 4GBXD 1J8CA 4OZFH 4GA2A 1FNLA 2F5BL 2VXQL 4RGOL 4ZSOB 4CMMA 1ZTMA 3P1MA 1ED3A 4RETB 3RK6A 2YD6A 1OB1B 4J4PA 5HP5A 1CFNA 2J1YA 2P3YA 4JHKA 4KKJA 2DWTA 1EEZB 4K23H 4U1NB 2F0YA 1BT0A 1KLFA 4XP6H 3T2PA 3GSNL 1G0YR 1YA0A 3WTXA 3QDHA 3V0WH 2KC1A 3GO1L 4LASL 4NGHL 1NA8A 5FOBA 3VI4E 4JAMB 1PL3A 2VZ1A 1ZDVA 4MA1B 3FRPB 4L3CA 4HKXA 5D2LE 2IJ0C 1OQOA 2VW7A 1U0QA 3UBXA 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4X4ZA 2AJXL 1YEGH 4D0BA 4LLQB 2QLYA 1UM5H 5HBBA 3PZ3A 4APXB 4IBZA 1QACA 3HMWL 3ORJA 5D4JA 3RDTC 3P9LB 3LZLA 1TZOA 2ZNWA 3IYLW 3KCWA 1DJYA 2NLJB 2ZCZA 4JA7A 4WUUA 4V3IA 3OKKB 3FT4A 1J0JA 3LQZB 2QHLA 4YDOA 5EPMB 4W9RA 4P5TC 2UUDK 3N41F 4L4VE 2HXAA 4L48A 2XA8H 4N24A 5KJ7E 3FT4B 3LKRB 2XEVA 2VKWA 3LQZA 3QEUB 4O58L 4PRBA 4MWFA 4RMSA 3UBXG 5HJGA 1JYNA 5AZEL 1D7BA 4J8YA 1KXVA 1LEKB 2QSCH 1HL4A 2UVFA 4NZJA 2J0MA 3HAEH 1JOIA 3SDXB 4JHAL 2YSTA 4QRRA 2IOIA 4WO0A 2IWGA 3A1QA 1BAWA 2BDNH 2JTDA 1ZDSA 4FAAB 4Z7AA 4OT1H 3NIGF 4J3OF 3ZT7A 2Y5TB 4HC1A 5C8JB 2XJKA 1UOKA 3ZJTA 2OMBA 2FECL 1GOZA 4KJPD 4IBQA 4AV5A 1XH3B 4GPMA 2GC7C 4WI9A 2OMYA 4N2GA 3T2LA 3UGUA 4YS4A 1LO3H 2EUWA 1B88A 4YDLB 1KF9B 4G71B 4JDZB 1XH3A 1I7HA 4Y5VB 4FQQB 3FB7B 4OF0A 3GPSA 4JGHB 5DHVB 2FL5B 4OZAA 1U3HD 3E1F1 2NY1D 2BWIA 2IH3B 4AK1A 2FQFA 5AVTB 4HHAA 3T77B 5AALA 5F72S 4W9LC 2H3XC 3ESOA 3G2WA 1RPKA 2Q7AA 5AKRA 4NRZA 3ZLZA 2DEXX 1ESOA 3FTSA 2BSCA 1YEKH 2VYIA 1KFAH 4F1SA 4Y5XC 3EU9A 4WUYA 1XF1A 4IMLA 2ORBL 3LIZH 3QIBB 1OGWA 2N7EA 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4HP5A 2EYSB 2MMXA 2EKEC 3M6DA 1LXDA 3TXNA 2YQ8A 1JP5A 1ZRUA 1PX3A 4PM1A 3NQIA 1XLOA 5AARA 2ITDB 3A6BL 4HEME 3TM6A 4XPHH 3SE4C 3L3OA 3TEWA 4OY9A 4J3UA 3TA3D 5DRWA 1INDL 3MYJB 2QYJA 4LNGA 1C5CH 1URIA 1P84J 1CBVL 1FNHA 5D1QB 3MLPA 4B93B 1N61A 2IDSA 3G04A 5AW7B 2EE6A 3GTNA 3W0WD 3W38A 2NY6D 1A7OH 4Y4KB 2VO8A 1WZ3A 4MJID 1YZZA 4KQ0A 2DYMA 5L7XL 5AAWC 2APBA 1TITA 1C76A 4F2MA 5EBLB 4XNQB 1Z3YA 2OPCA 4MCZA 3BWUD 4HOQA 3HZVB 4LLQA 2ZIRA 1DTUA 3E6HA 2XZAL 4DX5D 4CMMB 3ILDA 1IVLA 2IALB 3FUIA 3NABH 5CCKL 4K7FA 3B9AA 4R0LA 4WO4D 4N85A 5KAQF 1DQJB 1LFDA 2ICIA 4M8NA 4YBHA 3GIVB 3L3KB 4JMNA 1JS4A 3QW9A 3T0VA 3CFCL 3ZDYF 4CDNA 3VI4F 2IH3A 4IOSD 4XPTL 3HG4A 5KG9B 2FL5A 3HC0A 5AKSA 2C7HA 4JEGB 3RO2A 1QILA 3FCTB 2X9YA 3QI9B 4X6BB 3V4UL 1SXZA 3QARA 1WA1X 3NFSH 1GGTA 1OTRB 4KK5C 1GPOH 1YJ1A 3VXTA 2PNNA 5FKAC 3AKKA 4PJEB 4NN5C 1YEIH 5I6PA 1Z5LA 1ZV2A 1UH3A 3V6EB 4JZYA 2MQCA 2W8CA 1W72H 1SLUA 3CBKB 2NW2B 4QTIH 2IV9A 4R7NA 1NIEA 3KEAA 1NMCC 4XCFH 5F0MB 5J1AB 2KQ4X 2VL4A 1NAKH 4GFTB 2L32A 2NZ9C 4HXBH 4LDCA 2DMGA 3NJMA 1A6WH 2VXSL 2VM4A 4FEIA 4B9GA 4PJAF 3LH9A 1UT1A 3V79C 2ED8A 2ETAA 4OAVB 2A1WL 4X6DE 2J71A 3S8FB 2Y07L 1I8MB 1C78A 1KEMH 1OUVA 4O2EA 2HPOA 1UZ8B 4GCOA 2ZUQC 3O65B 3CZSA 3K8LA 5F1NA 4LU5L 4XVOA 3VG0L 5IESL 2CA3A 4UZGA 4GZ6A 3D39D 2KDIA 3ZDYB 4L8DB 4NUQA 4BELD 3VM7A 5L4JA 4XCEB 1MDAA 3DARA 1X5MA 3JWDH 4XVSH 2A38A 4CU6A 4KTGA 4WH4A 3U6XA 4QDGA 2J9QA 2GBTA 4JM0A 4Y1AD 1UGJA 4B0MA 4G24A 2E56A 4DEWA 2D73A 4OI7A 2OJ1A 1P7HL 4GMJA 1L0PA 1AZBA 3TF4A 2B59A 3PJSB 2V2WB 4G80A 1NCHA 3FSOA 3UROR 4J8FA 4OM0L 4W9EC 2WXLA 1KEGH 2RSUA 3DRAA 3RTQA 2O2VA 3ULVE 3OKEA 1DANU 2IWFA 2P26A 3F58H 2D4FA 1TZ1A 3KD4A 1OAUL 4L1LA 5DC2A 5IVXE 3IJYB 2X4PA 4FYQA 3I9GL 4XMPH 2X89D 4GLRH 1TTUA 1DVFD 5D96C 5BYRA 4WHYH 3EHQA 2E0IA 3DJTA 2I6HA 1AJ7L 2WVUA 3ABGA 3FFDB 3K72B 5JHLL 1FFPA 1N3NA 4PTUB 4MGZE 1WFJA 4XVUD 4TM9A 3D9MA 3TNMB 4ZMLA 1TETH 1IBHA 1W72B 1MFUA 3AS1A 5IMOA 1X3DA 4AGMA 2WDQB 1QOFA 1KJ2A 2V0PA 2KLTA 3N43F 4DXAB 1ZBPA 1PEZA 3KR3L 4ZODA 3D4CA 3MRFA 1CQYA 1RJLB 2A4CA 4AL8L 1ZHBB 5FV1L 1WFMA 5DK2B 4JM2D 1M1XB 3BP4A 4PREB 4HLZG 4LRNL 1RZ8B 2NCMA 3QZWG 3WGUB 1S3KH 1J0YA 3K0WA 4OD1L 4CYEA 2VITA 1MLCA 3P3SA 1ZLVH 2XU9A 2GJRA 1VESA 3N1FC 2AKRA 4JJHA 4X4XA 3V0EA 3VU2A 1WD8A 2G4DB 1K6QH 1KTJA 1M71A 4OZGF 3MRMB 4TVPL 4WFHD 4ZAKC 3GSVB 4ENEC 1MNNA 4QQIA 1P5VA 2AK4E 3L5XL 1NGZA 3P2DA 3NEEA 5ECGA 1P7KA 5F8RC 4G5AA 3TWXA 5AAWA 2Y7NA 2A6DA 3GRWL 3CBJB 4JHZA 1P7QD 2Q10A 2WTRB 3NIGE 4M1CD 5D7GA 3CLEL 5GGQH 1YYLH 4NPNA 3QI9D 4ZYKB 4O1NA 4RCOA 4Y4KA 3MXVH 5AUMA 3SGEI 5KVEH 2GTZA 3L4WA 3P1UA 1KTLA 4PV1C 3C12A 1V3MA 1ZVSB 2DQIH 5ESQB 3ZTDA 1QR4A 4IOFD 1B1ZA 4D0DA 2BC4A 4IHOB 5JIMA 3LVEA 3TCLB 2AHIA 1EUTA 3HI1B 4DN3H 1XR9B 4OB5H 2QTVA 3QIBD 3RB5A 4ALAC 3WELA 1N0XH 5K9QI 4WJOA 5E9NA 1MREL 4KKLC 1I8UA 2FWOB 4XDDA 1HCFX 4PD4J 4NN6C 5DFVD 2NY5L 1VFAA 3I9PA 4HPOH 4YHYC 5HG2A 3O8XD 1OB1A 4ZD3L 4KKZA 3QNZA 3IMUA 1FQ9C 3L6FA 5DMKA 2NCNA 3DVGX 4BUHA 4JX0A 5LGJB 4JQIL 4XP4H 5EIIA 4UCFA 1FIQA 3A9JA 4E9XA 2IO0B 3VFGL 5E08H 2WNWA 2YPVL 4JG0L 1BBDL 3W5MA 5CBAB 2NW2A 4MCMA 1T4KA 1PFCA 2I9LB 4Q52A 5D55A 4Q6IC 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3K3QA 1R75A 4OCNC 5CCMA 4WFEE 2DYPB 5DRNA 3UTSD 3RI5F 3EU5A 3TV3L 1JMLA 4LK0M 4P9HL 4PYUA 4HHAB 4XKBA 4OZFA 1DOYA 1PGBA 1LJMA 2G5UA 8FABA 4PY8I 3NGBC 4IKIA 2Y4TA 3EW3B 3KVFB 3WIHA 4Y4FB 2X3CA 5CEZH 4ZHOA 1IUEA 4NJAH 1TZGH 1JNLH 1C5BH 1Z1WA 4TNGA 2XZCH 5EIIB 4V2BA 3Q2LA 5I73B 2MW5A 3UINB 2DEYX 4MAZA 2YA1A 4MKMA 2VZOA 3HI5L 3MNDA 3POHA 4RAVB 4YHIA 3FULA 3BD4A 3TG4A 1OWWA 3QE5A 4EIGB 3MLSH 2B20A 3MFGA 4KV5F 1RK1A 5EC2A 1AR1B 1LEIB 2QPDB 5I24A 4GZCA 3GBDA 3RUGE 5KHQA 5GSVB 5FZQA 3CFDB 4LESA 5F1NB 1WIAA 1UZ6F 3DURA 5LQBH 3P40A 3D50A 3QIBC 1PZ5B 4PR5B 5D7JD 5MERB 1U21A 1I35A 2GUYA 2VDLH 2WWKO 1EEQA 5DR5H 3JCKC 4BZ2H 3VQLA 3JWNC 1INQA 2C9RA 2IQ9H 1Y07A 4HZ1A 2E46A 3VFPB 5JPMB 3DTXA 1ET9A 4YIQB 2HAZA 2NQCA 2YMXH 1BAGA 1SJED 4DW2H 4PJEF 4QKTA 4MS8C 4PJ8D 5F3BA 2W82A 3I3NA 5HI7A 1S7VB 3BAKA 4Y9BA 4ICVA 4RRPA 2OMVB 1MCIA 4LLAA 3JW0X 4JRXB 2DJMA 4N0UA 2HSIA 4G8IA 3GW4A 2CSPA 1YNTA 5EIVA 2Z1PA 1MW1A 2MWCA 1RY7B 3SOBL 1JCSA 4L3EE 4M1GH 1XO3A 4OZHF 1AR1C 3GUTB 5EU4B 1MAMH 3A4EA 4Q9CA 2JB6A 3ZQ9A 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2P52A 3ULVC 3D9HA 1YUHB 5C3JB 2OEVA 2VDOL 2WK2A 3IJHB 2EC8A 3DVNU 4RFEB 1D7FA 4XCFL 3K2UL 2ROYA 4GKSB 4K7SA 4HEPG 1DQLH 1NAKL 2CM6A 4OCRL 3VXTB 4HH9A 1JCRA 3RWJA 1S0PA 2VKXA 1FSKC 5AENA 2L0TB 5B1BB 4GOSA 4B7LA 2R17C 3DHMA 3L3OC 1UN8A 3ARGC 1YNTF 3D85B 2OJRA 3UI2A 2JB5H 1ZD6A 4HLEA 5BMFH 2K22A 3NJIA 4R97C 4KQ3H 1XGTB 3QNXA 4B95C 4BT9A 5LCWJ 3QCTL 4UBDD 3MJWA 4DERA 2LHAA 1Q9OA 3U6RA 4CGUB 5KVGH 1TSRA 4XBPA 4UDUC 1M05A 3WENA 1ZIBA 2R51A 2V7HA 4PJ5E 2MPAH 5CAYB 3U1SH 4K5CA 4JANB 5IJVB 1MDTA 1NEPA 4HJ1A 4K3EH 4PRHD 1E4JA 1NCUA 1RUMH 3BH9A 1KIRA 4TNFA 4N2MA 3ATDA 4ERSH 2A9MH 1IJ9A 4LBEA 5BZWA 1K50A 1JDCA 3AB5A 5FM5M 1FEHA 3MRRB 3NPSC 1PEWA 1QSFD 1RZIB 1NGPH 1ZDXA 1HQ4A 3TEXA 1OSEA 3L4YA 4BGDA 4P3DA 1ZGLM 4NAWA 3GHEH 3KWXA 2WDTB 5B7MA 1QYMA 1P1ZB 4N68A 5DS1A 1QZNA 3F04A 3VAEA 3M07A 2QR0A 5ENTD 1T1ZB 2IG2L 1RZ4A 2J4WL 2NNAB 3TN0C 5HY9B 3O0RH 5DD0L 3IG3A 2X1OA 2E27H 4JO5A 4H5SB 1FT1A 3KVQA 2Y69B 4IJ3C 5SWZA 4OD3H 2XG5A 1V80A 5JHDA 5KG9A 2JB6B 4G25A 2A6IA 4W9CA 4ODWA 2DQTH 3PHQA 3QC1A 5LXIB 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1AFVH 3RIFF 3MV7B 3GS4A 1MFEH 4AJVA 3QC5X 2VSKB 2F1BA 1YO4A 4OZHA 1BXAA 2VSDA 3IF1B 3PWVA 1YMME 1KLGA 3DO4A 5DJ8A 3Q6GL 4UTAL 1OARL 1JNLL 3AG2B 3MMEA 1HSAA 3OLIA 2VL5A 5ID0A 3IGLA 2OMXB 5DUBB 3IU3B 2EEDA 4WTQA 32C2A 2C7UA 4OTXL 5ITFB 3ZU8A 4A9AA 3DV4B 2QKIB 2ZX7A 4HK3J 3QNKA 2ZCKH 3EBGA 4Z23A 4RGOS 2IBZY 2PLTA 3VRJB 1AP7A 2CG9X 3PNRB 1HWHB 3Q8AA 5ICUA 2FX9L 2OTWA 1FFVA 3II2A 3APFA 1BF8A 3SGKA 2IVFC 2OULB 1MN4A 3UZQA 4G6KH 1GMEA 3MV9E 4NFCA 1XO8A 3CVCA 2E7CA 4FG2A 5I76B 3JVFC 3AKLA 2X10A 1TYQG 4A2GA 1L6UA 5AQBA 3JYBA 3K4ZA 3DX9B 1NUFA 2LFEA 5DZ9A 4KQ4H 3QFJB 4LFHG 4HUWA 4PRPB 1AD9A 4RMBA 1KIUB 1OCRB 2OCCE 2CGRL 4ONHA 4TQ8A 4Y16B 1MCJA 3NH7L 1F3RB 1G6JA 1ROEA 4X7TA 3P63A 4XVUC 5K9OB 5CO1A 1EXUA 4EXKA 5DUMH 5JOEA 3GXIA 3GZPA 3N91A 4XP5H 4NIYE 3R66C 1QR1B 1BWMA 3E8UL 3QQDA 3FUNA 1DEEB 5HHXH 4FQJH 2EH8H 1CE6A 2Z3FA 2MFNA 3BPNC 3LXAA 3MUUA 4XPBH 1ACYH 3T3MB 2MOWA 1G9EA 4OHJA 4U05A 4QOKB 4P5TA 3UTSE 4AGLA 2JXMA 3RN9C 5I1AB 1QFWI 3QORD 1UWEL 4KKBD 4X6DA 2EP6A 3NFNB 3O3AB 4NN7B 3SDAA 4IYKA 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