1E8XA

Structural insights into phoshoinositide 3-kinase enzymatic mechanism and signalling
Total Genus 267
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
267
sequence length
951
structure length
841
Chain Sequence
AASEETLAFQRQLNALIGYDVTDVSNVHDDELEFTRRRLVTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCVFIVIHRSTTSQTIKVSADDTPGTILQSFFTKMANERDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRKECDRKFRVKIRGIDIPVLPRTADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCQLLYYVNLLLIDHRFLLRHGEYVLHMWQLSGFNADKLTSATNPDKENSMSISILLDNHPIALEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQQEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLPQSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine
pubmed doi rcsb
source organism Sus scrofa
molecule tags Phosphoinositide 3-kinase gamma
molecule keywords PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT
total genus 267
structure length 841
sequence length 951
ec nomenclature ec 2.7.1.153: Phosphatidylinositol-4,5-bisphosphate 3-kinase.
pdb deposition date 2000-10-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00454 PI3_PI4_kinase Phosphatidylinositol 3- and 4-kinase
A PF00613 PI3Ka Phosphoinositide 3-kinase family, accessory domain (PIK domain)
A PF00792 PI3K_C2 Phosphoinositide 3-kinase C2
A PF00794 PI3K_rbd PI3-kinase family, ras-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1070.11 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 Phosphatidylinositol 3-/4-kinase, catalytic domain 1e8xA05
1.25.40.70 Mainly Alpha Alpha Horseshoe Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat 1e8xA03
2.60.40.150 Mainly Beta Sandwich Immunoglobulin-like C2 domain 1e8xA02
3.10.20.90 Alpha Beta Roll Ubiquitin-like (UB roll) Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 1e8xA01
3.30.1010.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 1e8xA04
5KHQA 4AOFA 1RLWA 3GOEA 5IA7A 3VTVA 2MCNB 3ZTCA 1SE9A 2LGXA 1V80A 3ZUNA 2CU1A 4TKNA 3APDA 3R7RA 4LJPB 3ZW3A 4GB9A 4BKSA 2DHZA 5ANLA 4NAWA 4WJOA 2LASA 2N9EB 5G55A 4FADA 1WGGA 1J19A 2M0XA 2EP6A 3PREA 2A4ZA 1GJZA 1WRDB 2LGYA 3QHTA 4TV3A 4P7IA 5JHBA 3FBKA 2Y3AA 2NBWB 4HDQA 2RD0A 2GBMA 2WXFA 4KDLB 3RULA 2N1VA 2K6QA 3RYTA 2KJ6A 2C7NB 3B1LX 2KD0A 3HM3A 2QZ5A 2ISDA 4KITB 2N7EA 4GSWA 2D3GA 1WR1A 2ENPA 2WXGA 2Z0UA 1KM7A 4JL9A 4MH0E 1LQBA 2I9CA 4ANVA 2NS5A 4IG7B 3QC8B 4AP4C 1WJ4A 1V5OA 4FHJA 3PVLA 1G6JA 4F92B 2WYQA 4A20A 1I42A 3W1SA 3ZDTA 1WJ6A 2Q0ZX 2NBUA 3ENEA 2X6HA 3L10B 2C7MB 3N30A 2L05A 3JSVB 4MEMA 4F91B 4HCNB 2KJHB 2PEAA 4II3B 2X6IA 3TIXA 2D8KA 2YOAA 5G2NA 2DAJA 4ANWA 2IBIB 2J0MA 4BFRA 2MBEA 4HCPB 3A33B 4W9FA 1UOWA 4WAFA 5J17A 4NQLB 2UYZB 5AZFA 2KQ7A 4ASWC 5L83A 1YIWA 4HVBA 4J6IA 2K3HA 1TGZB 1WXSA 1WX7A 3SDLC 1NBFC 3WA0A 4AWJA 4QJ3B 2NCEA 1WX9A 2K6DB 4IWOA 4CO7A 1A5RA 4KZCA 5CCJA 1WYWB 2K8CA 2XK5B 2RPQA 4L1BA 3V62A 4IW0A 2UWQA 1WXVA 1E90A 4DK5A 3RDJA 1IP9A 2KDFB 2CHZA 3A9KA 2ZEQA 4BKTA 4FLHA 3ZIMA 2FJUB 2L0TA 4GMVA 5TR5A 2L7RA 4MJJA 1T0YA 2FUHB 2G45B 3CMMB 4KSKC 4W9EA 4PS3A 3N3KB 1WGYA 2CS4A 2WXLA 4K1RB 5CTRC 2FIDA 5LLIA 1NI2A 2EKEC 3VUYA 3NHEB 2JQZA 3LS8A 2N9PC 1TJMA 3OLMD 4GIVA 1UOVA 2BWFA 2KN5A 3A4RA 2D11A 2BKFA 3HK0A 5BO4B 2ZPNA 4EUTA 1R4NI 1C3TA 2B3RA 3RT3B 1DJIA 4IQHA 5H4ZA 1WF9A 1M94A 1YRKA 3PGEA 4A55A 3UIPB 4A3PA 3VVWB 2K8BA 2AL3A 1DSYA 1WI0A 4FJZA 3IG3A 2D10A 1Z5SB 3W1SC 1KJTA 3NOBA 4TQ1A 1KOTA 2G4SA 4L2YA 2WXRA 1JRUA 4WWPA 4CYEA 2JF5A 2L3ZA 2KFKB 2WXNA 4NJ6A 3KUDB 3WAMA 4JGHB 2RSUA 1WM3A 1U4AA 3VTWA 2KXJA 3VDZA 3M95A 1UGMA 2J0KA 2KWVB 3U8ZA 3PTFC 3QJZA 1UD7A 4TQ0A 1X1MA 4IM2A 4OVUA 2C5LC 2WXOA 2IO0B 5ENNA 3MHSD 5HKHA 5CCHE 4QJ5B 1XQQA 2LXAA 2MLBA 2O2VB 3T8MA 2O6VD 3T9LA 4PS8A 3L4CA 3DPDA 1ISNA 2V1YA 2MW5A 1ZW7A 4RM9A 4EEWA 4IUMB 1PQSA 1LM8B 3HN8A 4MGIE 3KWUA 1OEYJ 1WR6E 2NQ3A 1UBQA 1V86A 2JRIB 2KX3A 2M17A 3JVZX 2PE9A 4F7ZA 2EMTA 3PRPB 2DAFA 3TCAA 3ZVVA 1DQVA 4UWLA 3PHXB 4IHBA 4HDOA 4JIOU 3H7PB 4DHJD 2AL6A 2X6JA 3L16A 2FK9A 4IWPA 3L17A 5DCNA 2KLGA 1TJXA 1YX6B 2D2QA 2OOBB 2DENB 3H9DA 3S2AA 4DDID 2G4DB 2FCQA 3PV1A 2MWSB 3JYUA 2N7DA 4MJSB 3APFA 2LRUA 2KC2A 3AI5A 3Q3FA 4RM8A 5H4YA 1SGHA 2MA9B 2DZKA 2DMGA 4F93B 1V81A 1DJZA 3H7PA 4B6WA 5E6NA 4M8MA 2HE7A 1EUVB 3B08A 5C1ZA 1YQBA 4ANXA 5LXIB 3KYCD 1WZ0A 1OQYA 2NCNA 4F8CB 3W1YA 5D6JB 3ZNID 4NP9A 4AJYB 2X38A 1YD8U 2IO1B 2LRWA 3A9JA 3I3TB 2PJHA 2FCSA 3UF8A 3B7YA 3L08A 3UGBB 3IBEA 1CMXB 2JUOA 2KHWB 1RFAA 2KTRA 3HIZA 2M8SA 3EHVA 5GMVA 1KLVA 1L2NA 1OTRB 3IFWB 3ONSA 1V49A 4DBGA 1MG8A 1Q0WB 3OJ4B 2WXQA 3P2BA 1WX8A 4FBJB 3PHWB 4KIKA 3EC8A 2FIFA 1WZ3A 4JPSA 1BDYA 4IC7B 4HK2A 1BCIA 2KX0A 1RRBA 3VAWA 3JSVA 3GZNI 1UELA 2KWCA 2KLCA 3X0WA 1E8ZA 2PPHA 2ASQA 4IM0A 2IYDB 3M7FB 4DDGD 2L76A 2LWPA 2Z0DB 2GBKA 4DWFA 3PYCA 1UBIA 1IYFA 3O65B 1ZGUB 1P98A 2CHXA 1NDDA 2G3QB 4KZ0A 4GGQA 3L13A 4LDTB 5T8IA 4NS0A 3PRZA 2IO2B 4XE0A 2WXPA 1S1QB 2QHOA 2WX1A 4ZDVA 1Q1OA 3QK0A 1E8WA 3ZO5B 3ZRCA 4DNLA 4AUQC 2MBOA 2DYMA 2DYOA 2Z59B 4WJPA 1YX5B 5J2RA 1GNUA 2KC1A 2XK5A 4MSQB 2XEWA 4UWKA 2K1FA 4BBNC 5AEKB 2NPTB 4FN2A 1ZKHA 3JZYA 2CKHB 4CHKA 3DBLI 1V5TA 2B3AA 2L8JA 3NZSA 4A3OA 4G50A 3KUZA 5E6PA 3UQBA 4II2B 2FNJB 1LXDA 2CJTA 3UINB 3DBHI 2KI6A 4G3XB 5FR6A 3RD2A 3A9KB 4NJ7A 3ML8A 3IM1A 2Y5BB 3ALBA 3CF6E 5JH5C 2OJRA 4PS7A 3TL5A 3A1QA 4KDIC 2LJ5A 2ZPYA 2I1KA 3VUXA 4KSLC 3W57A 4IWQA 4B95A 1QASA 1WJUA 2JZZA 3VFKA 5EDSA 3Q3JA 3SU8X 1I35A 2KK8A 1QZEA 4ZYNA 3QX1A 3WIMA 4WWNA 3ZNGC 1W16A 2K8MA 2HJ8A 3QQ8B 2ENQA 3L54A 2V4LA 3W56A 4FJVB 4PYUA 4E74A 4GN1A 4RMAA 2IO3B 3QR1A 1UH6A 2LGDA 3CSFA 4ZRKA 3F04A 2JZ3B 2KNBA 5CHVC 3RCZA 1C1YB 3VH3B 4FJYA 2EMSA 4QAMB 2KMCA 2Z0EB 1WH3A 4ZRIA 3RZWC 4B9KA 1P0RA 2WWZA 4MDKE 2K25A 4WQOB 2KZRA 3BY4B 3PFQA 1GMIA 2DX5B 3HHMA 1FXTB 2GBRA 2LHAA 4Y1TA 3N5AA 1VD2A 1Q5WB 2KWUB 3K9PB 4W9JA 2M1MA 1V27A 1F9JA 4DHJB 4NNJB 2CHWA 5CCGE 3ECIA 3DBSA 1DJWA 1WMHB 3TBLD 4OVVA 2YVCA 4V11A 4HPMB 1UGKA 1H8CA 3AU4A 1WM2A 2FCMA 4URKA 2JT4B 2KTRB 5AZGA 2V3SA 2KDEB 1H4RA 5IAAC 1GG3A 3EFUA 1TTNA 4NPKA 3RPBA 1GUAB 2GMIC 2HTHA 1E5WA 2NVUI 3DVGY 3VUWA 4NPNA 3ZNZB 2WXJA 1RAXA 1WMHA 5CHWA 2KANA 1E8YA 4FHKA 4JLCA 3QIJA 3JW0X 2NSQA 4GXBA 5J18A 2JPHA 3BINA 2R2QA 3PPAA 2KFJA 4BOZB 4BVUC 1D3ZA 3UQAA 3GPEA 4ANUA 2L00B 4K7UA 2ZVOA 1DJGA 2K8HA 3C0RB 2L0FA 4GOCA 3PLVA 2JY6A 3VHTC 4W9DA 2IY1B 3M3JA 1S3SG 1E8XA 1RH8A 2BYVE 2ZJDA 3K9OB 3QWZB 4L23A 1WFYA 3KWTA 2ZNVB 4GU2A 1YJ1A 4I6LB 4WWOA 3A4SC 4LCDE 2BYFA 1WE6A 3PSEB 5DPTA 3B0AA 2R83A 3IHPC 1HE8A 5D7GA 1WXAA 4MGYE 2Q3XA 2MP2B 4GDLA 3TJPA 2KOXA 3RUIB 2JRHA 2YRBA 1Y8RC 2DZIA 4MGZE 4EZKA 1J8CA 4EZLA 2RGFA 3R66C 4WJQA 4DHZB 4BKGA 4I6NB 2BGFA 2NPTA 3U30A 4OYSA 2C7HA 4FA6A 4LDCA 2R2OA 3KYDD 1WY8A 3D32A 2N1TE 1EO6A 1V6EA 2CR5A 3NSJA 3APCA 5KJ7E 3M62B 3UIOB 3H6NA 4MGKE 4UWGA 2CM5A 3NZUA 4ICVA 4UWFA 2MRPA 3N32A 3V60A 4NPJA 4DHZE 4E71A 4EOYA 4K7SA 1CJAA 4HLEA 1WGDA 2DZJA 2YLMA 1IPGA 1L7YA 2N1WA 1E7VA 3AU5A 2REXA 2KMAA 4ICXA 2HD5B 2M4NA 2IY0B 4F1SA 4KV2A 2O2VA 2WX0A 2MQJA 3LDZE 3IVFA 3PLUA 2N9XA 1J0GA 2BYEA 1XD3B 3AXCA 3V6CB 2LXCA 2JWZA 3X23A 3VH4B 1K5WA 2ZCCA 1WFMA 3VTUA 4XX5A 1WGRA 1WJNA 2J7QB 2KDBA 4WJNA 1SIFA 2KJRA 4Y1SA 1R4MI 3F01A 2DZMA 4EZJA 4M0WB 2XBBC 4FULA 2VRRB 1V2YA 4LDTD 1AARA 4NQKE 2I1JA 3MTNB 2BPSA 4EKUA 4W9LA 2WXHA 4L1LA 3QAQA 4MELA 2MSED 3DBRI 2O6VA 2C60A 4KIKB 3ZRFA 4X57B 1EF1A 1TBEA 3RZFA 4HWIB 1WXMA 2WXKA 4PH4B 3L9BA 2KVRA 2N4FA 1DJXA 2LVQA 4MJSA 4WAAA 2LI5A 3L0WB 4QJ4B 2K39A 3DDCB 5D2MB 2BF8B 2ZVNA 4M8NA 4W9HA 3NS8A 2KO3A 3KVFB 4K81A 4E3CA 3PS6A 2K4AA 2GBJA 1Z2MA 3OJ3A 2KKCA 4BBNF 2X6KA 5L95C 3CSTA 3SD5A 2GBNA 4NY0A 2DYBA 5LXHA 4MM3A 3NY5A 3LJ3A 4K7WA 2DMHA 2CM6A 1K8RB 3DVGX 4W9GA 2MBHA 2RR9A 3OHMB 4N9F4 3MJWA 2ENJA 4ICWA 2BWES 4YL8A 3WALA 2WDTB 3TWYA 3KUCB 1A25A 4IM3A 2LVOA 4LT7A 3ZTDA 3QR0A 3DQVA 3DOWA 4I6PA 4HPLB 4JQWC 5JZEB 4AJWA 5CHFA 3AULA 3F00A 4LJOB 1W15A 2CHDA 2MBQA 2A5UA 1V9JA 2C9WB 4HJKA 3ZKJC 2LZ6A 2LD9A 3H1UA 2NBVB 2IZVB 4WEEA 5DPSA 1OGWA 3H7SA 4ICUA 4XZ4A 2AEHA 1WFJA 4HXDA 5DPWA 1RLFA 4GNKB 2AWTA 2WXMA 2ZCBA 1DJHA 3F05A 3OAWA 1BT0A 4GDKA 3ZNHB 4LCVA 4ZRJA 2FAZA 3ZDMC 2ZZPB 2KQSA 2ZKMX 3FDWA 4G0NB 3VXWA 2PE6B 5JHAA 2QZQA 2AYOB 2D07B 3EECA 2KDIA 3M63B 2WXIA 4XC2A 5KHOA 3WAOA 2UZPA 3IHYA 2CJSA 1LFDA 2ZNVC 3QA8A 2JVCA 4GDKB 1P9DU 3DVNV 2W9NA 4TS6A 2O6VB 1VCBA 3TMPB 3PRMB 2KTFA 2KFKA 1OEYA 3WAPA 1BYNA 1XT9B 5E6OA 1UZXB 4BGDA 4W9CA 5D94A 4EFOA 4TUUA 1GC7A 2X6FA 3DCGA 2LUEA 3V6EB 2BKRB 3R7QA 3A9JB 2LVPA 3U7DA 2FCNA 3A1QB 4PYZA 4DXAB 2BWQA 2MBBB 4W9IA 5CX3A 3KW5B 3WANA 4UWHA 1CJYA 3QARA 3VQIA 1WE7A 1WIAA 3PZDA 2JXXA 3QCAA 4BKSD 1TZ1A 3ML9A 3SHQA 2NR2A 3KH0A 1GC6A 1E7UA 3V61A 4KVGB 3PT2B 1RSYA 2J0JA 5DPRA 2K45A 1WGHA 2MP2A 4G11A 3DVNU 1P1AA 3R3MA 4GDLB 4BOSC 5AZHA 4MSMB 1EF5A 1QATA 2GOWA 2MX2A 3HM6X 4W9KA 3ZLZA 1DJYA 1P3QU 4NAWB 5C23A
chains in the Genus database with same CATH superfamily
3KS2A 5TJWK 3RIKA 3FRPA 5BOZG 1XGPA 3C5ZC 4MWFB 3SGKC 4YE4H 5I1HH 2A3TA 3ZW3A 1GOZA 4K3CA 4N2DA 1S7TB 2WQXA 1FDLH 3D0LB 1GGUA 5G55A 3EBAA 5E8EA 1SF0A 1T1YB 5AWNL 2DEYX 2RJMA 4LXFA 1NWOA 5JMRA 4JDZB 1I31A 3KVDD 3ZKNC 2EIZA 3BMWA 1XLQA 4ONFL 1WZAA 2CSPA 2HKHH 2X05A 3MUY1 4IRJC 4D3CL 1J88A 3MRFB 2VITB 4GKOA 3K5SA 3IU4L 4P23B 2W0FA 3QYNA 2EUVA 1GZHA 2ENPA 1YY9D 4XWGH 1AGDB 1JNNL 1GOFA 4LGSB 4GO6B 3BPNC 1AMYA 1EDYA 3HB3C 5I18H 3ARQA 4ANVA 3P4RB 2P5EB 2QPDB 2P7TB 5CJQH 3C2AH 3V5KA 1KLUD 1XLPA 1V5OA 1I53A 3K2MC 2Y2WA 43CAA 2PP8A 3CLEH 3SN6N 2EILB 2IO5A 4WO4D 1AZNA 5BO1L 4DW2H 4A20A 1EO7A 2NBUA 4G8IA 3L4ZA 2UVEA 3FRUA 2AP2A 4HA1A 5C2BL 1OIOA 5EZLB 2F7IA 4ZDHA 3QYMA 4KNQA 1OB1B 3MC8A 3T0VA 4EXKA 4LLYA 2LOEA 3OKMB 4I8DA 3ULSA 2XIIA 1UOWA 4HJJH 1ROCA 4ZMVA 3GWJA 3H9ZA 1V7NH 3ULVD 5BNWA 3HFML 5GS0H 2IMNA 3A21A 2FX7L 4XHJC 5C08A 2FL5A 3RURA 3U7YH 5L9DH 5L83A 1DCLA 1EBPA 1S9YA 3STLB 1DQDL 1WX7A 3S88L 2C34A 5ESVA 1HQRB 3HS0B 4OLVL 3ASDA 4WUKL 5JXVA 3IDJB 3BN9C 4NKDB 4K7PL 4GQQA 3AXLB 4WWKA 4HF5L 3DX0A 1M71B 4L1SA 1WXVA 4AENB 3LEYH 1IP9A 5FLUA 4NLAA 4FLHA 3ZIMA 3U36B 3TG4A 3QDGD 3GBMH 3QIUC 1FNGB 4JO8A 2YBRA 1M53A 4IK6A 4APXA 4PS3A 1Q0YH 3ABVB 2X6AA 2CS4A 3C5SB 3QJUB 1J8KA 1D6VL 4LCYA 5JDSB 3L4UA 1RHHB 3SGEH 1PNDA 5I76B 3M1BA 1C3TA 2Y9RT 1DJIA 5H4ZA 2EADA 5B7MA 2M56B 4ZRPA 3ZN6A 1XZWA 3W9EB 4F2MA 3L3IB 4IRUA 1S63A 4CCAA 1ETA1 1SQ2N 2IVFC 1IC4H 3CDYA 3Q5OA 4U1LB 3HRPA 3ZZLA 5L8KB 3Q2CA 4X7EC 1HL8A 2ZSVA 4IRZH 1GA2A 4OB5H 4OZHF 4AVKA 3SDYH 1ED3A 4W68A 1I4QA 4A90A 4N3AA 4WUYA 1S7QA 4P3DA 5CZVH 2R23A 3GJEA 1RHFA 1O5PA 1PLCA 5J56B 1IEBA 5DRXB 2NX5D 5JOEA 5C3TA 3LY9A 3RVXC 2ZOKB 2N0SB 1HKLL 1Q9LB 4TLSA 5GGUB 4K3JH 2KAJA 1SXNA 3Q5YA 5L88H 4OVUA 2ROYA 2C5LC 1ZWIA 2E3VA 3TXNA 5I1KL 3SY0A 3TU6A 3NCBB 2ZW1A 4NKMB 5CF3A 2HX9A 3Q69A 1E9OA 3W2DH 1T2XA 3PUUA 3PY9A 1YMME 4J8FA 4U2YA 1BQ5A 2KZWA 4GIPD 4LLQA 4Q4IA 4LG6A 5I26A 1BLIA 2KX3A 2Q7FA 3GMMA 2ZSWB 1UBQA 3JVZX 5F7KC 1JYXA 1GJWA 4MB4A 5C9KA 2LVCA 3TCAA 5E2JA 1BJ1J 1DUYB 3NJKA 4UWLA 4TM9A 1JNNH 2UXVA 3ARPA 2VABA 2VZSA 3F6LA 4JDEA 5I18L 1D7FA 4JJHA 2G3XA 2OHFA 2DBLH 4XPAH 5C08D 1PLAA 3S2AA 3NJJA 2UU7A 4AQEB 4IBZA 1E6JL 2GJPA 1U8JB 5DIZA 3MOBL 3S34H 5DVOA 4HW6A 3AACA 2DOCA 3OMIB 4UM9A 4ODTH 1C4CA 3U0TA 4F93B 3MBED 1P9MA 4PVLA 5AZ2L 2A9DA 4B6WA 4FDWA 1WFUA 2XN9B 5DUPH 4YR6A 3KYCD 4HETA 2EDMA 5KYUA 5KUKA 1YD8U 4D8OA 1WUZA 2AJVL 2AJAA 1OALA 1MX2A 2BFVL 3CVBA 3NH7L 5F7UA 2IMMA 4FZEH 4NZUL 1CMXB 2X6VA 2WBXA 3BK1A 3EUUA 2DDQL 5HYSA 4NQUA 1IMHC 4XMWA 3AE6B 2D7OA 4R7XA 3WG7E 4RFNB 4KRPD 3RWCB 4TUKH 3MA7B 2WD0A 3FQXB 3ZU7B 4WWID 1K8IB 3CK0L 2FVNA 2PZIA 3FU5A 1IC0A 2BOBB 2CJ3A 5HPMA 3GZNI 3MLSL 2KWCA 5ACMA 3X0WA 4MA7L 3DOIA 5HHMD 4D94A 1DEEB 2ITDA 4EBQL 3VFVA 3Q15A 4AGQA 1J5CA 4LSUL 2YBGA 4G1EB 3CSYB 5IESH 3U7YL 2XN2A 4Z3FA 3SYCA 5DZVA 3VYOA 3CZFA 3SQBA 1B88A 1CTMA 2AANA 4ZDVA 2G9HD 3SE4C 3ULUH 1HHGA 1KN4L 5I5JA 2VSOE 5DTFA 2EVIA 1D5MA 1MWAH 2K0PA 4DNLA 3O3DB 3O3EB 3HYMB 2ICEB 4OLEA 3MREB 4MSWB 2C9QA 5J2RA 1A6VL 3OKNA 3QUKB 1XCQL 1A7RH 2B1HL 2HG5A 2ROXA 3MV11 5ICYB 4UUCA 1BEYL 2NPTB 2KERA 2VLLA 3ARFB 4P5TD 3SBPA 1E4JA 2X2IA 4G50A 3SDDC 2VZKD 3I9GL 5CSBA 4M01A 3UINB 3FB8A 3B1TA 2OXHB 4NQSA 2J1KA 3DVGB 4MD0B 1IGCL 4XOBA 3MA9H 3SGKA 1NFKA 1OWPA 1JGIA 2EINE 3PFUA 1N4RA 1ZCRA 2XPZA 2TRYA 2BQQA 4N0FB 1ID2A 4DP2X 1E2ZA 4JHWH 5FO7B 1ZTXE 1AO7E 3SU8X 4A3VA 3B9KB 3BRDA 1IJ9A 1DVUA 1IILE 1XR8B 3BT0A 3QJVB 3L3GA 1KBGH 4DX6D 3MGAA 5JIKA 2YSSB 4CT0A 1MQ8A 3AKKA 1Z5LB 2VDLL 2Q8BL 3MLZL 3QG6B 4L8SB 4ZMXA 1E43A 9CGTA 5J6GB 1E10A 3DV4A 4KUZH 5B1CA 2BVOB 4S1RH 2AXJA 4ENED 4L3ED 1MSPA 2QVMA 3BIBX 3FFCB 3QAZB 2NMSA 1LO3H 1NC2D 4A38A 1C1YB 4X9IA 5TPWL 3UX9B 2SEBB 2R17C 1EYHA 2FO8A 2VDML 2XWCA 5IESL 3ZEFA 3KSLA 3QG7L 4F9PA 1YEEH 2DX5B 1AQ8A 1T80A 3BCDA 3D0AA 2A74C 5DUPL 5F0MB 2A9ML 1DJWA 2WBWB 2N9LA 2NXYC 3FN0L 3QP3A 2Y2TA 4G6ML 5IROC 4FI8A 1TQBB 3UPRA 2KTRB 3NSFA 4GTPA 2H0FA 5I1CL 3EFUA 2D03L 3D2TA 1GUAB 4LSRL 2CNYA 4LL4A 4UILL 4N1EA 1N19A 3VGAB 1BFOA 1X5FA 3CZLA 1E8YA 4HIHA 2Q9OA 1Y18A 2NT1A 4HBCH 2N1KA 2PMZA 3RWCA 3ARDB 4P59L 1F45A 4DVBA 2KFJA 4M6MH 3P1MA 4YHKH 4I1OB 1LO2L 4HROA 1H2UA 4B53A 1AIZA 1X6NA 2R69L 1PU0A 3ZTNL 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1MFWA 3OBAA 4WI0A 1ZE3D 4HPLB 3SE8H 4K9JA 2QGCA 5IHHA 4FS0A 4U1GC 2EXWC 3VD7A 3PPSA 1GAFH 4N8CH 2MPAH 5IVZB 5MERB 5IQOA 5JQIB 3PGCB 3BGMB 4J28A 4I43A 2L7QA 4QRPE 3ZGIA 3T2QA 2FEJA 3D18A 5H94B 3FXIC 3WIAA 1BT0A 2C9UA 2PYED 4JHVA 1MJ0A 5CINL 1QHPA 4KWUA 4EDXB 1HHJA 1TR7A 3C9NA 3K71A 4LVNB 4Y9GA 1KLGD 2CCVA 4ERSH 1CK0L 4XPGL 1PDXA 4LPCA 1IO4C 2X12A 1NKGA 3Q49B 2CCLA 3W3BA 2JVCA 4UOZA 1G6RL 4OLYL 2W9NA 1J8HA 5INCB 2AABL 4HS3A 5AVUB 3WAPA 4I13B 4WSGA 2WWMC 3W9DB 1MCEA 4PBDA 4B95C 3PCYA 3Q43A 3DX4A 4K9EC 3OSKA 5JJ6A 3WENA 1DQQB 4N6RA 1Y7VA 1XCQB 1E4KA 4CU7A 1HG5A 1U8LB 3GRGA 2X87A 1NBZB 3L3DB 4JKNA 1DBBL 1FRDA 3RWEB 3N0PB 2APSA 1HQ4B 3S7GA 2MTPA 4R6UA 2BRRH 4O1NA 2YK1L 3ULVE 5J6SA 1DVZA 1ET5A 4N0UE 5C0CB 3HS0C 1NPUA 3HM6X 1V54B 1BMWA 3ARFC 4KKAD 1L9SA 5I17A 4TQEL 4P59H 1RLWA 1T3FA 3AQXA 3QI9D 2XX1A 5G5HA 1OZUA 2A73B 3GDCA 1WH0A 3ZTCA 2V0PA 3AECB 2N7AA 5E23A 1TZHB 3GB7B 3LHPL 1CD9B 3QDGE 3GSWA 4NNYA 4WGVB 3LZOA 1IAMA 5HYJE 5I75B 4KI5C 3HN3A 5HVWA 1WRDB 4OF3A 1P7QA 1YEHL 4KFZC 5JHBA 4LCCB 4OJAA 1MVYA 2RD0A 3IB4A 3KLSX 3W9CB 2NY1C 5BCAA 1YN4A 3ZHDA 2JH2A 3HG1B 1F5WA 3H0TB 3NMEA 5EOTA 3CVDA 3W2DA 1SYSA 1H2VC 3CIAA 5FIOA 1BQUA 2J7LA 3DX8B 2KYWA 1IT9L 2I9CA 1DBKL 3VH8G 5AW3B 4YZFE 4JG1H 4DKAA 3QA3A 4MAYB 3ZKMD 1NP7A 1FGVL 3MNZA 4G82A 2NX5E 4G80B 1D7CA 3E8UL 3CHXA 1BBJA 4GSUA 3N30A 2DH3A 3L5HA 2X4NA 4JZJB 2FBOJ 3CFQA 4M29A 4L05A 2BCMA 3PP3K 1RKRA 3U9PL 3LRSB 3SCMA 5HVFB 2XJKA 4A7UA 1B0IA 4KBQA 3VFSA 4ZMYA 3NOCD 3ZR5A 4G7QB 1ADQL 1DANT 4U4BA 2GJZB 5I73B 4FNPA 3LNDA 3PAUA 4JKLA 4HP5A 4OSUL 2GRIA 4NFDA 1TGZB 1XH3B 3TNNA 3ARGB 3BX7C 4OFYD 4ORGB 3IFLH 3C8KA 1MW3A 1UJ3C 3FU8A 3MLXL 4X6DE 2K8CA 4PP1D 3TC9A 4B9IA 4TUJB 4L1BA 3DETD 4YFDB 4JPKH 2YQ3A 4LB8A 2XSKA 5F9OH 1PZ5B 1K8DB 5LCWJ 1NPNA 3HXFA 4JR9H 2XETA 3HUJF 4GAGH 2E56A 1J1PH 3DURB 1JXGA 4ZW5A 1F1HA 1A1OA 1DQLH 1A1OB 4TQ8A 1R19A 3QQ3B 1DQTA 4TULH 3AMKA 1KXVA 4MAYD 5D6CB 5TD4A 2Q20A 4K8RC 2V7NA 3JTSB 2R29A 2CLRB 3BZ5A 3MUJA 4FMFA 4RETB 3J5QB 4PGDA 4G42B 5AB0A 1QSZA 3OLMD 2AQSA 3Q1SL 1LL1A 1QI4A 32C2A 4LFHD 5EV7A 1AYFA 1U41A 5F1IB 1E27B 1NUDA 5BO4B 2IEPA 4L3CA 4H2CA 1MWOA 3LNHA 1LNUA 3BKMH 4F15C 4O00A 1S7SA 1DZBA 5KHQA 4AEIH 2VERN 4I2ZA 2NNFA 4P99A 1N68A 2BS4B 2ZISA 4K7PY 3ESLA 5CN2A 4KOCA 5T5FL 2LXMA 1FGVH 2R61A 4ONOA 2OZ4L 3C5ZA 1KYDA 1SUJA 2HJKB 1M3IA 3EJPA 5IBUG 1Z9LA 4KY2A 5DYOB 2DB8A 4JM0A 5FM5M 2DWDA 3CHOA 3DGDA 1U4AA 5E1AB 5J6HA 3JQ1A 4QHUA 1FFOA 1PY1A 3C98A 3DSXA 4WUUB 4BFJA 3U8ZA 4QCIB 4JREC 2O61B 4FFYH 2B2XL 1PX3A 4WNGA 4BSJA 1X1MA 3V9EA 3ABME 2WXOA 2R2EA 2WZ0A 2PO6D 2BRRL 1FCGA 5E6ID 1DNPA 4PS8A 5TE7H 1TUPA 3QNXB 3E9UA 3CNKA 4HNAD 2QPFA 4MGIE 4APFA 5IF0A 4DWHA 3HTLX 3BAEH 1LWJA 1G0XA 2FATH 3GXNA 4RH4A 5DHVB 4R84A 1QPXA 1S5IL 1YJDC 3LHPH 3NAWA 4UNIA 2ODHA 2DQIL 3B2GA 1R0AL 2KLGA 2K6YA 5LBSL 3VFRA 5CZVL 3BZEB 5ACZB 4K71C 3MKQB 3FQUB 4KPHL 3ARXA 4PI2A 5DI8B 1N5XA 3JYUA 3RUGF 4FG6D 1FXIA 4KROD 2B1OA 4R26L 4RM8A 2LLNA 3GSWB 4NNYB 5J08A 4OZGE 1NMAL 1G9EA 5JPNA 2ORBL 4NO2A 3LZQA 1MI0A 3SY0B 3AUWB 1OWNA 1OQYA 3ZDWA 5D1QA 1O75A 3UIOC 4FKEA 3BOVA 3V52L 2W9EL 4GTVA 4O4YH 4WIPA 5B3NA 1O9ZA 1TVBA 3H3PH 4WRLA 3RHWF 3ZZSA 1MJ7L 2KTRA 5GMVA 3FU9A 3B2VL 4YGVA 1K3ZD 1IARB 5EBMA 3V6FB 1D6EA 2C3VB 3FT1A 4FU3A 3AZUA 1CFSB 1FNAA 1BJMA 3GRBA 4MCZA 2ZSVB 5D1XE 1MFEL 4OB5L 3WFEL 2F58L 4JPSA 1YMMA 4YO0A 3Q7JA 3CFBA 4JG9A 1SPDA 4DUVA 1M4KA 2WNMA 4HK2A 1QEWB 4XWOC 1QAWA 4FFWC 1KIPB 4I3GA 2J8OA 2W60B 5IHZB 3CFDA 5BT1A 2Q2EB 2E2EA 1QABA 5ANMB 1HI6B 3BLBA 7FABL 2YPLD 1AE6L 4DPRA 2EILE 3M7FB 4DDGD 4FA8A 1HHIA 2X6MA 1WAAE 3VA6A 3AG2E 1RUKH 3FTSA 4XCFH 4NN5B 4BD4A 4ZUTA 1JGEA 3WTSA 3H4HA 2XNAC 3O11A 3VTMA 1QPPA 1OAUH 3VMPA 4TKWA 2IPUG 4PJ5A 3C5ZB 3V4PH 5C07E 1GNUA 4P3CL 4GZDA 2OSYA 1P7KB 3ZE0E 2IOIA 2VZOA 1EFXD 3C2AL 3HS0A 4X9YA 3PGCA 4B5ZA 4FN2A 3BVNA 5H37A 3V9CA 1SBSH 3BUIA 3ARFA 2B3AA 5JO5A 4OAUC 2X1XR 2HG5B 2J1ZA 3MA9L 3FO9B 3VFNA 3DBHI 2KI6A 1RL1A 3OKMA 4K7PX 1PLGL 2B20A 2Y5BB 4FNSA 1IE4A 5BXFB 2FYYA 2RAMA 4KTYA 1ZHBB 4J4PA 1MCDA 2XA8L 3MX0A 3GS4A 3Q05A 4CGWA 4GMTL 2R2CA 5BZDA 2PYEB 2W9DH 4PBVC 8FABB 2JZZA 3Q3JA 5T5FH 1Q9KA 2EVFA 1A6VH 3DURA 4XEIG 4JR9L 3IXAA 5I6LA 1OCZE 2P7TA 1K8DA 3KPNA 3OG4B 3MRQB 4MD4A 2C7UB 4TL5A 3L54A 3VQLA 4KTDL 1AJ7H 3BH8A 5I1HL 1IT9H 3CV0A 4HPMB 2UX7A 1UH6A 3IVKB 5D6DC 2FJFA 1EJ8A 3GEFA 3D9MA 1MI5E 2X70B 3Q1SH 1I8IA 1TU2B 3BVWA 4PM1A 4PRNB 1PQZA 4WEMB 1BZ8A 4WWKC 3GI9L 3QXUA 5B1JC 3ZPDA 3JZ7A 5EU5A 1JDDA 2TAAA 1SW6A 5G5DA 5ICXB 1AOZA 1XBDA 3U1SL 5DQ9B 1OVZA 1CIDA 3RWJA 4LK0M 2K4WA 1WM2A 3FQWA 4L1TA 2JT4B 2CBOA 1G7QB 5EF2A 4KKLC 1ZKAA 3VU2A 5FLVA 1TTNA 1C12A 4MTMA 4N2LA 2DL2A 2A77L 2IFFL 3T1WA 1SLUA 3PE4A 3ZNZB 1XGPB 2QELA 2KLSA 4JFFB 1M2VB 3AE2B 4JLCA 2Z65C 3QUXB 1N54A 3LRKA 1NAKL 2YAQA 3CKBA 2E74C 4NQDE 3U0PA 1OKEA 4NENB 3PPAA 1Z9PA 1BHGA 3UZQA 4DEPB 3QISA 5I19H 1KY7A 3EH5B 1I7ZA 2AJZA 3HAEG 2KPWA 3H0TA 4YSDA 4W9DA 1KIUB 4JHAL 1N5YH 2BYVE 2ICES 4RESB 1E4XH 4GU2A 1B4LA 1D5ZB 5HHXH 3CFKA 2PLTA 4YC2C 1D7BA 3BVTA 1AIFA 4U07A 3ZQ9A 1LE5B 2RFMA 2E9BA 3CVQA 3RUIB 1CC3A 1H15A 3BCFA 4QPEA 5KNHD 4HT1L 5IOIA 1VGKB 1ML0A 2E7DA 1AOHA 4DHZB 4NKMA 2Y1ZA 4DP4X 2GJRA 3SBTB 4GRWB 4K3HA 1RJLA 3TZVA 2VH5L 1N7ML 5GS1C 4FA6A 3PV7A 3ZE2B 5KVEE 2O72A 1GZPA 3D32A 2FR4A 2VAJA 3DO7A 1T3FB 1WV7T 1PAZA 3FF8A 1U8HB 4TVPL 2ZNXA 3LKSA 2ZU6B 4DGIH 3CVCA 1Q9LA 3V60A 4JREB 3LHAA 4IDLA 1PMYA 1CJAA 1L7YA 3WGVB 5J1TC 3BAWA 5AZ2H 3SDDB 5L88L 2PWHA 2ZXQA 4X8XA 1PL3A 2FNWA 3ATFA 4W6YB 4EVNB 5LNDA 1U8CB 1JZDC 3LKOB 3QUZD 1FZMA 4FG6C 2J53A 4QTFA 4QRFA 1I3GL 3CFCL 1WGRA 2WDVB 3VXTA 4TXVB 5FCSH 1NMCC 5ETUB 1CLYL 2VXSH 1UWYA 1ZS2A 3N40F 3KCPB 4N87A 4GLSC 2AABH 4LBAA 4OFQA 4HS3B 5ERWB 5JA8B 4PV9B 4N5QA 3VA2C 1NAML 1G6RH 4OLYH 1OP9A 3GSOA 3Q8CA 2O5XL 2JCCE 3QZWA 3WY4A 5L4IA 5BMFH 2X9YA 4RMSA 2HJ1A 2N4FA 4EOWH 1LO5D 4MDIA 3U36A 4FQ2L 1RERA 1DBBH 3TCLA 2FGWH 5FKAB 5G4OA 2PN5A 3BU8A 1PLGH 4N2EA 3GSNH 4RFOH 3CVNA 4FOMA 3HE6C 4ODXA 4RBPK 3WXXA 5MI0C 4G8AC 1J11A 5TDNA 4I9WD 2YAHA 4LSZE 2F08A 3IMSA 2X9WA 4KK6D 2MQ0A 2CXKA 3A3YB 4DQOL 4G8FB 3MUGB 1SBBA 1CK0H 4XPGH 3P1UA 2B08A 1TNNA 2XJLA 3G5XB 1MFBH 1MW1A 5EU4B 5IJKC 4WURA 3DQVA 2Y1AA 4JA9A 4JQWC 2BS3B 4MDIB 4AJWA 1F56A 3RY6C 5I15H 1D2PA 4FQXA 2EDRA 1G7HB 3SE3C 5DMYA 1BJ8A 1R6VA 5JA9A 1N95A 1BVNT 2B6CA 3ZN3A 3GSOB 1LWRA 3IKKA 2R51A 3DMMA 4G5AA 2V5FA 4XVSH 4XAKD 1OGWA 1DFBH 2WCPA 4AIZA 4OGAC 4CMMA 4IU2B 5KVDH 2R8SH 3OG6B 4JQXA 2H26B 5DZ9A 5DPWA 1NGQH 5T1LB 1IGMH 5F72S 3V8OA 4D0DB 2Z9TA 1IM9B 1XAKA 43C9B 3FUMA 3QJSB 4HXAH 2CU3A 3MRFA 2NLJB 2IDFA 1C79A 5DMIL 4TUMA 4JG5A 3EECA 4QEGA 1T89A 3TA3D 3ZPJA 4UT9H 3RO3A 2JK5B 3UJTL 4ESKA 2CNZA 3IWVA 3D9LA 4R2GC 1KCRL 2VXSL 1NDGB 1WHPA 1X5ZA 3EH1A 4WW2B 3H4FA 4XAWH 4HFWA 5FWRA 2ZUWA 3U9UB 5J13B 1Z9MA 3MOQA 1AWDA 5L7XH 4WDIA 4L8BB 4BGDA 2FO1E 2OJZL 2YQBA 2CK0L 5F89B 2XTJB 4HHGA 4AY6A 3E38A 3LS5L 3U6XS 4P06A 5AYTA 1CR9L 5I75C 1SDDB 5HHOA 1DANU 3J5PA 2EINB 2BEDA 3O3BB 3DO7B 1SGKA 3D39B 3RDTA 4MWFA 3QJRB 4LNKA 2HG0A 3QEGL 3QNYB 3PZDA 5SX4H 5I4DA 3ZGQA 2VDLB 4MXWH 1KULA 1NZRA 1VGEL 3OKLA 4LEEA 5LGYA 4Z7QF 1MVKA 3RKVA 4LDEB 3V61A 1K1BA 3NJHA 2V3EA 5DVNA 4YTMB 5GRVK 3VDAA 5J11C 1LE5A 1SJVA 2JYTA 1ZJBA 1SE3A 3NRZA 3O4OC 2GOWA 3DLQR 4MFHA 4NB7A 2DBJA 3ISYA 2XOTA 1B4TA 4I9CA 1UT2A 3FFCE 4TPRH 4TQPA 3D34A 3G5XA 2LXLA 1SE9A 3IFOB 3MUGA 5I82A 2ONDA 4WZ9A 3RG1C 5FHAH 2BW2A 3EO9L 4PYGA 2NSMA 3CPLB 4HOZA 1P4IL 2K9XA 2D3LA 4EQ2A 2GB1A 4MMXA 3JQ0A 2KYIA 2QSCH 2VDKH 1S7RA 1XCTB 2ZXWB 5GRVL 4AKPA 2RMMA 4ODXB 1E4XL 4EQFA 1T5WB 3OAZK 4J27A 4DX7D 3FBKA 3PDNA 4J6RL 1HYRC 3DSTA 2YRLA 1J9RA 3QFJE 1BLNB 1ZV2A 2XCMC 4FI6A 3WNJA 3IMBA 4MA3B 2A6IB 3TCLB 4JB8P 5JORB 3AWGA 1AHWA 1OGSA 2MQGA 4Y0GA 5JHLL 3FQWB 2XG4B 2V5RA 2VB5A 4MRCA 1DBAL 5ABZA 4L4VA 2QY7A 4HAFA 1MPAL 4X80L 4DXGA 2G2RA 3IJSA 4IG7B 1ES0A 1W0VB 3LIZH 1MHCB 1TPXC 4PVNA 4XNYH 5EIQA 3VSQA 4XO8A 1VFMA 4Z8FL 4N3TA 5DQDL 2HMID