3TJPA

Crystal structure of pi3k gamma with n6-(3,4-dimethoxyphenyl)-2-morpholino-[4,5'-bipyrimidine]-2',6-diamine
Total Genus 250
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
250
sequence length
950
structure length
840
Chain Sequence
SEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTKMQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKECDRKFRVKIRGIDIPVLTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCVRLLYYVNLLLIDHRFLLRRGEYVLHMWQISGKSFNADKLTSATNPDKENSMSISILLDNYCHPAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTANETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNERVPFVLTPDFLFVMGTSGKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Identification of 5-(2,4-dimorpholinopyrimidin-6-yl)-4-(trifluoromethyl)pyridin-2-amine (NVP-BKM120) as a Potent, Selective and Orally Bioavailable Class I PI3 Kinase Inhibitor for the Treatment of Cancer
rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
molecule keywords Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic sub
total genus 250
structure length 840
sequence length 950
ec nomenclature ec 2.7.1.153: Phosphatidylinositol-4,5-bisphosphate 3-kinase.
pdb deposition date 2011-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00454 PI3_PI4_kinase Phosphatidylinositol 3- and 4-kinase
A PF00613 PI3Ka Phosphoinositide 3-kinase family, accessory domain (PIK domain)
A PF00792 PI3K_C2 Phosphoinositide 3-kinase C2
A PF00794 PI3K_rbd PI3-kinase family, ras-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1070.11 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 Phosphatidylinositol 3-/4-kinase, catalytic domain 3tjpA05
1.25.40.70 Mainly Alpha Alpha Horseshoe Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat 3tjpA03
2.60.40.150 Mainly Beta Sandwich Immunoglobulin-like C2 domain 3tjpA02
3.10.20.90 Alpha Beta Roll Ubiquitin-like (UB roll) Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 3tjpA01
3.30.1010.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 3tjpA04
4UWKA 4GOCA 4W9LA 1V5TA 3FDWA 1WXSA 3L54A 3L16A 3RULA 2NCEA 3PRMB 5J17A 2N9EB 3B0AA 2GBJA 2MA9B 4RM9A 2X6FA 1WGYA 3UGBB 2JZ3B 4X57B 3VUXA 5AZGA 2BWES 1WZ0A 3R66C 4EKUA 3JSVB 1X1MA 2DZKA 1QATA 1D3ZA 4AJWA 1W15A 2AL3A 4OYSA 1Q1OA 3VTWA 4URKA 1WXVA 3APFA 5ANLA 2J0KA 1WXAA 2L76A 5EDSA 2WXGA 2ZZPB 2HTHA 2KWCA 4MM3A 2WXJA 3VTVA 3V61A 4BKSA 4GDKA 1SE9A 2O2VB 5KJ7E 1UELA 4DBGA 4UWHA 2X38A 4MJJA 2FCQA 4PS8A 3TL5A 2XBBC 1UOWA 2Y3AA 1VD2A 2LVOA 1LM8B 3PTFC 3DBRI 1BCIA 3JW0X 3A9JA 1WR1A 2CHZA 2KJRA 2HE7A 3PHWB 5DPRA 2EP6A 3RT3B 3VQIA 1RLFA 2B3RA 3ZTCA 3QC8B 3PT2B 1J0GA 3QARA 1WI0A 2L05A 2KQSA 4JIOU 4NS0A 2D3GA 3HK0A 4MDKE 5AEKB 1DJZA 4WJOA 2M1MA 2WX1A 2YVCA 4XX5A 2LWPA 3DBSA 2IO3B 4NPKA 2CHWA 1DJGA 3UINB 3PVLA 2C60A 2LI5A 3VHTC 3RCZA 3JYUA 2UWQA 4FA6A 1K5WA 1WGGA 1Q0WB 4W9HA 3VAWA 4BBNF 4BVUC 2C5LC 2MBEA 1UBIA 2KVRA 3NY5A 3QAQA 3L4CA 2L0TA 3SDLC 4PS3A 4GDLA 3EC8A 1P98A 1RSYA 1WX8A 1SGHA 2O2VA 1MG8A 2CHXA 2QZ5A 1RRBA 2KMAA 3V6EB 4DHJD 5CTRC 2LGXA 4F92B 3JSVA 3PRZA 1WFYA 1J19A 2N9XA 2NCNA 3EECA 2NBUA 4WJQA 3KH0A 4Y1TA 1E8YA 3F05A 2MBBB 4UWLA 4I6PA 2G45B 4UWFA 3ALBA 4JL9A 2KJ6A 1P9DU 3EFUA 3WIMA 4MELA 1OEYJ 2L00B 3RPBA 2IY1B 2ZPNA 4KDIC 3HHMA 3H7PB 3W1SC 3ZO5B 4F8CB 4EFOA 5L95C 4IW0A 1Z5SB 2MSED 2K1FA 1V5OA 1IP9A 4FHJA 4MSMB 3OLMD 1GC6A 2B3AA 4WWNA 2I1JA 2KFJA 2KO3A 4IM0A 5BO4B 3ZRFA 3QQ8B 1NDDA 2BGFA 1IYFA 3F04A 2MX2A 1WYWB 3DVNV 3QHTA 2MCNB 5AZFA 1G6JA 4MGKE 4IM3A 3LDZE 3MHSD 1WXMA 2LASA 3GPEA 2KLGA 2NVUI 1EUVB 2MW5A 2KFKB 4XC2A 5JZEB 2LHAA 1YJ1A 3HIZA 2FIDA 3F01A 3QX1A 4LCDE 4EEWA 3TCAA 1UH6A 1TGZB 1OEYA 2V4LA 3L17A 4GB9A 4ZRKA 4L2YA 2KK8A 3CF6E 4DNLA 2KDBA 1DJWA 3RZWC 3WAOA 1UBQA 5JHBA 4GSWA 3PYCA 4LDTD 1OQYA 3VFKA 4KZ0A 1YX5B 1JRUA 3C0RB 4A3OA 2GBKA 2WXMA 2JQZA 4HCPB 3ZW3A 3ECIA 1XQQA 3X23A 1BT0A 2MQJA 4GMVA 4BOSC 5J18A 5D2MB 4B95A 2WXQA 2GMIC 2NS5A 3KW5B 1ISNA 1QASA 2BPSA 2KN5A 2MBQA 4FJZA 2FNJB 4BBNC 3RYTA 4HXDA 4HVBA 2M17A 2ISDA 2NBWB 2CJSA 1WY8A 2RSUA 4ZRIA 1EF1A 2ENJA 2PEAA 3AI5A 3WAMA 4NPJA 2PE9A 3L9BA 2BYFA 4W9EA 2JWZA 2JY6A 3PV1A 2Y5BB 1WR6E 4ZDVA 5CHWA 1WMHA 1WX7A 1WGRA 2BYVE 2EMSA 2R83A 3R7RA 2CJTA 2FIFA 4PH4B 1WJ4A 1LXDA 2KTRB 3IVFA 3JVZX 3IG3A 3M95A 2ZCCA 1V2YA 3QCAA 4GNKB 4P7IA 2XK5A 4MH0E 2JPHA 4W9GA 4G3XB 3CSTA 1UZXB 3D32A 2C7HA 2AEHA 3T9LA 3DVGX 3NSJA 1L2NA 2KC1A 2GBRA 2RR9A 4ASWC 2KXJA 1CMXB 1NBFC 1TZ1A 2N1WA 2WXPA 2QZQA 1WJ6A 5H4ZA 1Y8RC 3KUDB 4KZCA 3ZNHB 3VH3B 4FN2A 4WEEA 4ANWA 2WXFA 3PZDA 4JQWC 3GOEA 3VUWA 2DMGA 4TS6A 3UQAA 2HD5B 3B7YA 2FJUB 1W16A 4FJYA 4MJSB 3HN8A 3B08A 1E8WA 4BKGA 2WXOA 3PS6A 1E5WA 3A9KA 1DJHA 3W1YA 4FHKA 4YL8A 3QR1A 2MBOA 3IHPC 3Q3FA 5D7GA 1H8CA 3A9KB 4FULA 2PPHA 4EUTA 1LQBA 2ZNVB 1WM3A 4B6WA 3V62A 3HM6X 2D07B 3V60A 1FXTB 2KC2A 3ZNID 1GC7A 2AYOB 1WRDB 4KIKB 4JPSA 2KNBA 3W57A 3BINA 2OOBB 2I1KA 1EF5A 1SIFA 5JHAA 2YOAA 3WANA 5DPSA 2VRRB 3EHVA 2CM6A 1S3SG 2JVCA 5E6PA 3RUIB 3R7QA 1E8XA 1EO6A 3ML8A 3PRPB 3ZNGC 2O6VA 3WALA 4WQOB 2ZEQA 5KHQA 2L3ZA 2KWUB 4E3CA 2JRIB 4NAWB 4NY0A 1WGHA 1K8RB 1T0YA 1ZW7A 1E7UA 4K7SA 2JT4B 5J2RA 2K25A 5E6OA 1H4RA 1V6EA 3JZYA 2G3QB 3UIOB 3P2BA 5T8IA 4ICUA 5DPTA 1ZKHA 3X0WA 4GN1A 2G4DB 4F7ZA 3W1SA 3N32A 4HPLB 4TQ0A 1UD7A 2L7RA 2WXNA 2DYMA 2WDTB 3NZSA 2OJRA 2M4NA 3KYDD 2A4ZA 4KSKC 3VXWA 4LDCA 4K7UA 3VUYA 2N1TE 3DVGY 3UIPB 3RD2A 4J6IA 2WXRA 3DCGA 4NNJB 3L10B 5TR5A 1E90A 4M8NA 2Q3XA 2ZNVC 4IWQA 1QZEA 4EZKA 2GBMA 3AXCA 4K7WA 4W9KA 1KLVA 2X6IA 3PFQA 2CKHB 2W9NA 4HDQA 4PYZA 4DWFA 3M3JA 4GU2A 2FK9A 2Q0ZX 2LUEA 3QJZA 2RPQA 2LRWA 1GUAB 2XEWA 2K6DB 5HKHA 3O65B 3NS8A 3F00A 2LZ6A 3NZUA 3A33B 4AJYB 4ANVA 2NPTB 2KD0A 2EMTA 4GIVA 2PE6B 4KIKA 4EZJA 5IAAC 4ZRJA 3KUCB 5LXIB 4CHKA 4N9F4 3IBEA 1L7YA 4LT7A 4KV2A 2MLBA 4LJOB 3ZDMC 2ASQA 5DPWA 2DAJA 4DXAB 2N7EA 4HLEA 3DQVA 1E8ZA 4TV3A 2D8KA 1V49A 1WE7A 2BKRB 2LGYA 3TIXA 3L0WB 2N9PC 1I42A 3APCA 4LCVA 1OGWA 2CM5A 3QWZB 3NOBA 2CHDA 3ZIMA 2KI6A 1UGMA 3ENEA 2DENB 3ZLZA 2WXLA 3ZVVA 1V9JA 4QJ5B 1BYNA 2QHOA 4AWJA 3L13A 2DZJA 4QJ3B 2D2QA 4BGDA 4IG7B 1U4AA 4G11A 2KJHB 3DBLI 3RZFA 2WXIA 2DMHA 1PQSA 2KX0A 3L08A 2KWVB 4TQ1A 4BKSD 3DOWA 3GZNI 5D94A 3CSFA 2YLMA 2BWQA 1DJYA 3OHMB 1C1YB 2DYBA 4ICVA 4A3PA 2X6HA 4AUQC 4PYUA 3OAWA 4IC7B 3TBLD 3IM1A 2KDFB 2KKCA 2LGDA 2I9CA 2D11A 2REXA 3QA8A 2K8BA 3OJ4B 4NQLB 4IHBA 4MJSA 3N3KB 5D6JB 3K9PB 4II2B 1DJXA 1BDYA 1RAXA 2IY0B 1YX6B 2FAZA 4TKNA 2MP2B 2ZCBA 4NQKE 1YRKA 2FUHB 2ENPA 4DHJB 1CJYA 1V81A 3BY4B 3H6NA 3PLUA 3VDZA 2G4SA 2DAFA 2IBIB 3KWUA 2KHWB 3N5AA 2NPTA 3A1QB 2Z0EB 3CMMB 3B1LX 2UYZB 4V11A 1KOTA 2AL6A 2NBVB 3A4RA 3Q3JA 4LJPB 2LJ5A 3HM3A 2XK5B 1DSYA 1S1QB 1RLWA 2K39A 2KDIA 4IUMB 1YD8U 4W9FA 1DQVA 4XZ4A 4E71A 4F93B 2V1YA 4HDOA 4RMAA 5IA7A 1Z2MA 3ZUNA 2O6VD 5CCGE 2MWSB 4HK2A 4DDGD 2BKFA 1E7VA 5L83A 2IZVB 2DHZA 2J0JA 2N7DA 4K1RB 2L0FA 3VH4B 4DHZB 2MBHA 1XT9B 4AOFA 2WYQA 4I6NB 2WXHA 2IYDB 2M8SA 5LXHA 3SHQA 2A5UA 2LVPA 1KM7A 2YRBA 2GBNA 1C3TA 3U7DA 2RD0A 5GMVA 3S2AA 4IQHA 4KITB 3ZRCA 1WJUA 4WAAA 1V80A 4I6LB 5JH5C 2LXCA 1P1AA 4IWOA 1A25A 4KSLC 4MGYE 2FCNA 2KX3A 4KVGB 3U30A 4KDLB 3APDA 2R2QA 4E74A 3IHYA 1KJTA 2ZKMX 4G50A 1WGDA 1GJZA 5CCJA 2JXXA 1VCBA 2O6VB 3H7PA 4II3B 2ZVNA 4ICXA 4NP9A 3NHEB 2K3HA 1GNUA 4NAWA 1M94A 2DZIA 4BKTA 1WFMA 1P0RA 2KZRA 1YQBA 1IPGA 4DK5A 1WX9A 4GGQA 1WFJA 2Z59B 3PGEA 2JUOA 4B9KA 4MGZE 3ZKJC 4L23A 4W9JA 1YIWA 3R3MA 3WAPA 2ZVOA 2M0XA 3DBHI 4M0WB 4HJKA 3QIJA 2PJHA 3A1QA 4XE0A 3FBKA 4DHZE 4TUUA 2EKEC 2K8CA 4GDLB 3PREA 4EZLA 2DX5B 2CS4A 1WH3A 1R4MI 4ZYNA 4WAFA 1OTRB 2KDEB 2MP2A 1F9JA 5E6NA 3LJ3A 1TBEA 1UOVA 2L8JA 4EOYA 4K81A 2J7QB 4ANXA 2KTFA 2FCSA 4FLHA 1RH8A 2C7NB 2MRPA 5G2NA 3MTNB 2BYEA 2WWZA 2NSQA 4UWGA 3QK0A 1WIAA 5H4YA 1XD3B 1TJXA 4HPMB 3SU8X 4G0NB 1V27A 3ZTDA 4L1LA 2KOXA 4CO7A 2UZPA 4QAMB 4Y1SA 3DVNU 2Z0UA 4F91B 3N30A 4W9IA 4WJPA 2JRHA 3V6CB 2WXKA 3H1UA 3QR0A 2GOWA 2X6JA 4IWPA 5C23A 3PPAA 4FBJB 3A4SC 3A9JB 1I35A 3H7SA 4WWPA 4NJ7A 1WZ3A 2ZJDA 5KHOA 3ZDTA 2ENQA 1WJNA 2KANA 3KYCD 3PSEB 2KTRA 3H9DA 1A5RA 2X6KA 4PS7A 3ML9A 5G55A 3ONSA 5CX3A 1WMHB 3MJWA 4W9DA 1DJIA 3LS8A 2DZMA 2BF8B 2AWTA 3DDCB 3TMPB 4MGIE 2JZZA 3ZNZB 3VTUA 4MEMA 2CR5A 2LVQA 3AU5A 5DCNA 1J8CA 3I3TB 5LLIA 1GG3A 4WWOA 1TTNA 4CYEA 1HE8A 1P3QU 4LDTB 2LRUA 3M63B 3SD5A 2N1VA 2N4FA 3RDJA 3AU4A 3TWYA 4BOZB 4WJNA 1ZGUB 2IO2B 4JLCA 2HJ8A 3KVFB 3VVWB 4OVUA 4NJ6A 3UQBA 1WF9A 3M7FB 3M62B 2KMCA 4A20A 2K8HA 1V86A 1WE6A 4HWIB 3TJPA 4GDKB 2Z0DB 2K8MA 4QJ4B 4AP4C 1GMIA 5ENNA 4ANUA 4A55A 1R4NI 2K6QA 3PLVA 4FJVB 1UGKA 4JGHB 2V3SA 4MSQB 1NI2A 1RFAA 4OVVA 2K45A 3PHXB 2IO1B 2RGFA 3UF8A 4BFRA 2KLCA 4IM2A 5CHFA 3OJ3A 2R2OA 5FR6A 3IFWB 2C9WB 2D10A 4FADA 2DYOA 3T8MA 5CCHE 2J0MA 3AULA 4GXBA 3U8ZA 3DPDA 2BWFA 5C1ZA 2IO0B 2ZPYA 2NQ3A 1CJAA 4F1SA 3WA0A 4M8MA 2LXAA 2KQ7A 2CU1A 5CHVC 1Q5WB 4L1BA 1WM2A 4W9CA 2JF5A 2LD9A 2WX0A 2KFKA 4ICWA 3K9OB 1LFDA 3W56A 4DDID 1AARA 1TJMA 3KWTA 4RM8A 5AZHA 2NR2A 2K4AA 4HCNB 2FCMA 4NPNA 3KUZA 2C7MB
chains in the Genus database with same CATH superfamily
4R97B 4Y5XC 2EIDA 2L7JA 2OCCB 2FX9L 1BQ5A 3L54A 1PD1A 5B3JE 3MUY1 5AYUL 1OCWL 8CGTA 4YSOA 4X8JB 5J9PB 1IXVA 2JZ3B 1F00I 1XGUB 4X4YB 2BERA 1J10A 3IFLL 1PLBA 1S78C 3ESMA 3NN8A 2AL3A 5DD0L 1A0QL 4L3CA 1JWMB 4URKA 2VR8A 4JW3A 4H7YA 3TTSA 3GMQB 4JL1A 1NAKH 2HG5A 2YUXA 3T5XA 3QUML 3D33A 3GSQB 3KVPA 3VRIA 4FFVC 3NCXA 3VLEA 2ZXBA 3RKDC 1UOWA 3IU3A 2D31B 3NBNA 5AZEH 4XMKL 1ZB1A 3QQ3B 1JWGA 1X4ZA 5JOPE 1CC3A 4KXBA 4ZX5A 1E6EB 2KJRA 1N12A 2EDYA 3SGEI 3MLYH 1LGVA 4XPAH 4L9PA 4JQIA 3ZTCA 1JTPA 4F37K 5IBUG 1FFNB 2WV3A 4US9A 3QG6A 1IUZA 4PGZA 1ACZA 2ENYA 1UD3A 5IVZA 3G08A 3ZT5A 2WX1A 5I73C 2QIEB 1PX8A 4QTIL 4KJQC 5J6GA 2BSEA 2AK1L 3QJQB 3BWAB 2JK5A 4GRLB 2UWEE 4NPKA 5DD5H 3VI4B 1KBBA 1H8LA 4BE6A 2DQMA 5ENTD 1QOBA 4EHMA 3MR9B 2D7QA 1Q0WB 4HKZB 3KGUA 3X13B 2ZXDA 3PIQB 3RA7L 1I4RA 3QXDA 4JRFA 3UFIA 1UZ8A 1RSFA 2ZOOA 1OT1A 3FB6B 3U9PL 1VFUA 3D85D 5DYOB 1PYWB 1WEJL 4D9LH 3V6EB 1Q0YH 1MW3A 4LCCB 3UZEA 3RWHA 2R0KL 4DUIA 1SLUA 4O9HL 4ZQTA 4DQOC 1X5KA 1T4KB 3KLHC 2AK4E 3T9KA 2G2NA 1N3NB 4WI0A 3VXMB 2GRLA 3BRFA 2FJGB 3PWNB 3TBSB 3AREC 5H37H 1EV2E 1OEYJ 3LS4H 2B59B 2ICCA 2OP4H 3BPNB 3Q6GL 2FR4B 1KTDA 3O41B 1G6RA 3RZCA 5CLYA 4I1MA 1HHGA 3NFPB 5CGYC 4A7VA 1JPTL 4PB0L 1MOEA 5CILL 5EU7C 1ZT7B 4Y2OA 4BSXA 4ZUSA 3RX9A 1MG4A 1IAMA 5GS1B 5I9QC 4QKTA 3UQ3A 3GPEA 2KPNA 5DEGA 5EOCL 1U8NA 4UU9A 3EJSA 3VMNA 5EU4B 3BWUF 2DYSB 4N59A 4B9ZA 5D70L 4GB9A 4YT0B 3MLUH 3S5LA 3KYNA 4AQZA 4NJAL 2JI2A 3JTSA 3DTXA 1TKEA 5D3IB 1E6JL 2INDC 4AEFA 4G7SB 1JCKA 1OZUA 5IFHL 4LCCA 2FWOA 3VFKA 3PXHA 4NNYA 1N63A 2QVTA 4DZ8A 3C0RB 4HCPB 3NTCL 2DZEA 3NZ8A 1AW7A 3EGDA 4Y4FB 2MQJA 4N85A 5T1MB 1OM9A 3RY4A 5BW7A 4BKLB 5I66B 4UOQA 3ABKB 4YUEH 4ZOBA 5FGBA 1ISNA 4UQ9A 1I75A 1IBDA 4FJZA 4DI4A 5EZOH 4F7AA 1AHWC 1S7XB 4HWEL 4FNSA 3ZUCA 5FOBA 4HORA 3EYFB 2HPTA 5D72L 3VVVA 1EF1A 4ZTPL 2HVKB 5L8KB 1IHBA 3CXDH 3NS1A 3ABGA 3SD2A 3QUHA 3MRHA 4K3JL 3F65A 3AG4B 4ZUTB 4M1GL 4NQCA 1DL7H 3UTSD 3HA0A 1N0XL 4QTIH 2CJTA 3KPOB 4LDEB 2AZAA 4U2ZA 2FYYB 5ID1A 3K2UL 3S36L 3UOAB 5AAMC 2K7QA 3JSSA 4BZ1L 1HZLA 5CEDB 1IKNC 4PEEA 4JNXA 4XVOA 2P1YA 4JRYD 5DMKB 4JG5A 3ARDB 4JWSC 3DVGB 3DHJA 1JDCA 3S35L 2GBRA 2YD6A 1Y8RC 1PSKH 1C78A 3KUDB 3U2SA 3NRQA 2H6HA 5C7ZA 2D3BA 2B76B 1RUPL 5KYNA 3T5VA 3F7QA 3CSPA 4GP8B 1UNSA 3BW9A 1WITA 4MA8L 1EHLH 1MCPL 4IIQC 3MV9A 2Q3AA 5CMWA 2XV6B 1ZHKB 2V9TA 4IS6B 2IAMC 1DJHA 4Y5YC 3V10A 1L3WA 4NKQB 1AKJB 5DD0H 3IHPC 5KVGL 1UVQA 5IHHA 3LIZH 4RISH 4TVPH 4L3FA 3T65B 2EEXA 3TV8A 1S5HB 2WBJD 3MMEB 4TUKH 1FH2A 4MACA 2NY0D 5DJZB 2QLVB 4BV1A 4PUBL 1AR1C 2AEIT 4YDWA 1ZVNA 2VDOB 1MG3C 3REVA 4JY5H 2OEVA 3AKKA 1FNEB 1A3RL 1FQ9C 1XTMA 3GJEB 1TFPA 4FKHA 3CZNA 2VC2H 2VLKE 5MERA 3U52E 3V7AG 2R1WA 1PQSA 3RUIB 4OR1A 3BHBA 3HG4A 1U8HB 3FPYA 3WLBA 2HKHL 3RIAF 4PRHA 5FK9B 2IWKA 5JHDE 3WGUB 5FO9B 4B0MM 4AY5A 5LG6A 1EIBA 4AYFA 2V9QA 3O2WL 3K80A 3OKOB 3AB0C 2X4QA 3CSYB 4LCWE 4AYGA 5HVHC 5T3XE 2P8PB 5T3ZD 1A6ZA 4J3OG 1JMXA 3UL4A 4LNKA 3LXAA 1E5ZA 2DM4A 4XPHH 2Z4QA 2YC1A 3NMEA 1MPEA 3RHWF 4QRQB 4J6RH 1YMHA 4JGMA 4NFCA 1XIWC 2WK2A 4IYKA 2Y7QA 1WCBA 1UXSA 4U1MB 3A6CL 4ESKA 5G5HA 1FNLA 4Q9QH 3UKUG 1KLXA 3FWVA 4CN1A 4K07A 3ILEA 4QGYA 4WW1A 2NXZB 2DQDH 3VQMA 4DGIL 4DK6A 1X81A 1E4KC 1UD5A 1TG8A 4QR7A 2XNAC 4KK8D 1C5CH 5SWSB 4MQSB 4PJGF 2ZE0A 5B1AE 1CJEA 3DHHC 1MFAL 2QDWA 1TQTA 3QYCA 5IB1A 2WKOF 2ADJB 1I1AB 3S36X 3QDAA 2KD0A 3UAJA 2Y36H 1N52A 3OXRA 5B8CC 1WAPA 3SY6A 3NCMA 2CO6B 4Y2LA 1QI5A 4YDKH 2XN9D 2MLBA 2I60H 2KZBA 1KULA 2X4QB 2C4FU 1ACXA 4EBQL 3V79K 4LF3B 2VXSH 4WW2F 4GAAA 4B41A 5B39B 4NIYE 4PJCE 4FQXA 3GXPA 1PEZA 4GW4A 4LCVA 1U3HC 1U6AL 1RD6A 2CHDA 3ZIMA 5E8NB 2PTVA 1KYAA 3HUJF 3Q3GB 4QHKJ 3MX0A 1QI4A 3LS5L 2J57A 2P46B 3HE6D 1YEEH 3AKJA 4R5VA 3DOSB 1Q94A 1IC4H 3NA4A 1K6QL 4P5MB 4RSVA 1G4RA 4RMRA 2HFTA 4LFHG 1MFMA 2YRPA 4MJ4A 4ZD3L 1BLXB 3CC5B 3GGWA 4YDEA 3Q01A 5DFWH 5E2UL 5CN1A 4Q6KA 4A2DA 3FU5A 2K9UA 4TQ1A 3EF7A 1EDQA 5HY9A 4APQB 4AW7A 2DD8H 4D8OA 2WYTA 5I0WA 4U1LB 4ICVA 2B20A 4P1BC 1BVZA 1MQKL 1J8SA 4HIPA 2CKNA 5IV2A 5DGRA 2NTTA 4JFDB 4RGMB 5IVOA 2GJPA 2MCAA 4IS6A 3B56A 1SM3L 4XXWC 1TJCA 1R34A 4JA7A 2VSXE 3JV4A 3K81A 5C0RH 1RJLA 5J12B 2EDHA 4WU7B 1SVXA 3TLRA 3GJFB 4EI5C 2DWEA 3EYSH 1JNNL 4OW6A 4Y1AD 3Q8CA 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3KNBB 3V0GA 3UXGA 3OGCA 4B0MA 1KENH 4L1LA 3MC8A 4CO7A 2UZPA 4OTXH 3SQRA 4CDHA 5CZRA 3N30A 2GVYA 4TOYH 2HKAA 3GSXA 3MRIA 4BFOA 2EIBA 1UN8A 4KKNA 3ZL1A 3ZTJG 2YA2A 4AQEB 4YSCA 1A47A 5AKTA 3I63C 1E6OL 2AAAA 3ZNGA 4DRXE 4N4YB 4F9PA 5IMMA 3LYRA 5LQBH 3ZDTA 1QO3B 2CBMA 2DYPB 1NFKA 4FLSA 1E42A 4PS7A 4QYAA 3HXDA 2X9YA 2CXKA 5KJRL 1R9FA 1F1AA 1ZA6A 5BRZA 2P9IG 3CFMA 3KGRA 5TFSL 3WFDH 3ZXAC 4BWWA 4WW1B 2FO1A 2O26U 3SDDA 2WU5B 2OSLA 3VTUA 3QIBC 4FG6D 1F3DJ 4TXVB 4RA0C 3VFSB 1XAUA 2LXMA 3IPFA 3IJSB 3KJ4C 2YAMA 2G5UA 4E85A 3G04B 2J8SD 3WU1A 1QLEH 2HP4A 3ZDYB 2QCZA 3LNEA 4ONHB 3V0HA 5C9JA 5I1LA 5IOPA 5MEOB 4CKVX 2DDQH 4Y9CA 4TXQA 3T3PF 1UENA 1X4YA 4M03A 1UKQA 5FAAA 4WHTA 3QP3A 2APBA 4FEMA 2Z0DB 2OEDA 5K33A 2E2EA 3BXNB 5ENNA 3P3UA 1QRNE 3OTTA 1I1FB 2YQ8A 4HQQH 2DLBA 2F7RA 5ICUA 5TE6L 1NGPL 1N8ZA 4NQVA 1LO4H 3RO3A 5AOIA 2DYOA 3R8BA 4PJXA 3RWGB 1HXMA 5K1VA 3NUHB 1LEIA 2ITFA 2JE8A 4P5TC 1WM2A 4W9CA 2H1PL 4ODSL 2Z7WA 2ROYA 2XIIA 2BDNL 3GO1H 1EFXB 1IJNA 3DV6B 3BCFA 4G8KA 5FO7A 3O48A 4LLYB 2BWIA 4PJDE 5JO5B 4ADGA 3NH7H 4RNRA 4YDIH 4TVPE 1ADWA 4NPNA 2EUXA 3HG0A 4FXGB 3QDJE 2DWSA 3AQDA 3LSOB 3G04A 4A2EA 4AE0A 1NMCC 2QFCA 1IJ9A 1H3VA 4NQCE 3PRMB 5MEPB 4H0LC 1MAML 3FT3B 3BW9B 4K3BA 3D2UB 4DW2H 5BCAA 1O7DC 5H37A 1IQWH 2PPEA 2YQBA 4FNLL 4HCFA 4N5EC 3SYCA 3VXSD 3VFTA 2M83A 4CC1A 3MACH 4P46B 5HDRA 3WUWG 3KLDA 4X8GA 1MEXH 2Z92B 4N0UA 1F2QA 3SKNA 4OFYA 4M1CD 1NFDA 5T3ZE 3DVGA 4AVKA 2EVGA 2F5BH 1AHWA 1NSNL 3AJ7A 3IU4H 1YQ4B 4JHVA 2AV1A 3U7YL 3BUAA 5M95B 1RZ7H 3OG4B 3FPXA 2LVOA 1K6QH 2ICWJ 2ZWSA 1AO7D 1UFUA 4FTVD 2PKDA 3KS0H 1HO8A 2CHZA 1SY6H 3NJVA 1U8KB 2EIEA 2GFBB 2JKRM 4XPBH 3DWGC 5L4FA 3QC8B 3QIWD 2E27H 5E5MA 1CCZA 2VLKD 4IM8A 2D3GA 3SGKA 2KERA 4DP2X 1TNMA 3F7YB 5AW8B 1ZHBB 1J1PH 2O6DA 4WKZA 1WZLA 4EBQH 1G9HA 3EFCA 3TBCA 3N91A 1VLBA 4PW3A 4JFYA 4KAQL 4FG0A 3B3IB 1HX0A 2J21A 1A4BA 5L2JB 4G43A 4GLRH 3NVVA 2ADGB 3DMMA 5D8JL 3SDLC 1IGML 4HIHB 5LCWC 1YNTF 3LB8C 3MV8B 4MMZB 1EHNA 4AL8H 4TQ8A 2PPFA 4UDTB 3HC2A 3U7WL 2JYEA 3JSVA 2G5BB 1SJHA 3PRZA 4N0UB 1CGWA 5CLXA 3SBTB 3UM0A 1PDKA 3ZZQA 2MBBB 2NBUA 1CGTA 4ZRQA 3QEGH 1BIHA 4G5AA 4M61A 3SPCA 1X7SA 3FUMA 1BVLA 4M1DH 2AV7B 2ICEA 4XCEB 1KCVL 3IFPB 3W39A 1E5CA 1ACCA 1OEZW 1R5VB 1KY7A 3DURB 4WI6A 3FQXB 2FATH 3HG2A 4FLOA 5I6XB 2IY1B 4KDIC 2Y72A 1VPOL 4H8WC 1EZSA 2CBQA 2X87A 3FQRB 4EFOA 3GKZA 4IW0A 3BE1L 1LK3H 1Z5SB 5D7SL 1FZKB 5E6ZA 4H26A 4LQFL 2N0MA 4XVSH 5IHWA 2R2LA 1HZKA 2KO3A 2K70A 1D7FA 1TN6A 5HYQB 2BGFA 1IYFA 3WE6A 1A4KB 1WG0A 1AG6A 1DEDA 3E3QE 5I74C 3V6OA 3SKOB 2X4TB 3IDIB 4JQXA 3M88A 2C26A 4D9RD 1WXMA 2YLHA 4X7TA 3SO5A 4MNHB 5JZEB 1MCBA 3UI2A 4OQTL 4RWHA 1FZOB 1IKND 1X5YA 4Y4HC 2V4HC 3IE4A 4YSRA 3L17A 4WJKB 3NB2A 1WWBX 4F7EA 3H0TB 4U3SA 1M9SA 2KCLA 4XWGH 4YMPA 3NPZB 1IQDB 1QHOA 3WAOA 2PL2A 3IXAA 1BXTA 5G4NA 1NJ9B 1XCQA 3HRPA 3WXWL 3JT2A 1PD0A 4QRTB 4AIOA 2HSIA 1J86A 3RK6A 4HUWB 4M43H 5AOZA 1OQYA 4G42A 2C34A 1KJMA 4C4UA 2GBKA 1BI7B 1PGRB 3CK0H 4PMEA 1E2ZA 5ABZA 1GKEA 2QPFA 5I1EH 2PW2B 3IDNB 3WS3A 4MS8D 3ECIA 4LTUA 3HC4H 5AOKA 1N6ZA 3CVDA 4BOSC 1BQLL 2OTPA 2KLRA 1QWUA 1NAMA 2IC2A 4Q52A 3IAQA 4RESB 5EUOB 1HZ5A 4PRNB 1F1HA 1DQMH 4UI9C 3ZGZA 3IRZA 4ZSOA 2JK5B 1CT8B 2WM9A 4GRLA 1A9VA 3BDYH 1LDSA 2P4AB 2VW7A 1DZ0A 1H6EA 2NNAA 1J9RA 4Q0XH 4OFDA 5HI3D 3SE4C 3VGFA 1G1KA 3GSRA 1J9CT 1H3GA 4FL4C 5C0GA 4NWTH 2BVPA 2KC7A 4O5LL 4HJGA 3CFCH 5JPNB 4TKWA 1NBYB 5I6OA 5IMOB 2GY7B 4ODVH 1NC2D 4QEGA 2XKUA 4BERA 2Z6FA 4B9KC 3K2KA 1TZGL 1FFOB 4EI6B 2HUEA 3ZGQA 2L4OA 3B9EA 4KO9A 4TMAB 5AW1B 1OAUL 4S0RA 2WXPA 3Q9PA 2CH8A 5JTWA 1QBAA 1VEOA 4HKBB 3VFGL 3W37A 4WEEA 1WTGT 4JHRA 1BAFH 2BVQB 5CLZA 4LPTA 1YA0A 1P4UA 3S3DB 1ZTXL 3R0NA 4YL8A 4FXGA 3QR1A 3CIAA 4YXLH 2PPHA 1D2PA 1KXTB 1EEZA 5DVNA 4JMNA 4QRPA 5BXFA 3B13A 1X5HA 2Q20A 5EO0B 1O5MA 2P9SG 4X4XA 2VT0A 3WY1A 2ZISA 4FFYL 5HTSA 3M95A 1WYGA 3P40A 4EDXA 3CVQA 2B77A 2WMOA 3TNMA 5I2IB 4KVCH 3BINA 1K51A 1HEJC 2X70B 2OOBB 3U83A 5FHAH 5ABDE 4AUUA 2FZ3B 5K9OA 1LO5D 4BZ2H 4UQCA 1GOZA 3EJZD 3GRWL 5BMIA 5LBSA 4UINL 3VCLA 1JYNA 2OZNA 2D4FA 1AO7E 1J48A 2VITB 1B0GA 2B9AA 3MXVL 4NM4L 3WNIA 1JZIA 1WGHA 1N6UA 3V4LA 4M6AA 2E9JA 3HG1B 5TE7L 4DP0X 2ZF9A 4YFLI 4FI6A 3CDZA 3GM8A 4OSUH 2CO4A 3RL2B 2AXGB 4XAKD 5IOPB 5MEOA 2BSED 2XZQL 3L1FA 2AEQH 1P7QD 1R5IB 4G6ML 3WENA 4EAEA 3ZHKA 3BK1A 5EN5D 1HH9A 1GKOA 3HNSL 5E2VH 3T4YB 3VXWA 1ROCA 4D8PB 3BN9C 5C0NC 1U42A 1FFPB 3CZEA 1RJZB 1KIQA 2QGDA 2DVWA 5KG9B 3K72A 3MCKA 3WV0A 4ADJA 3DCGA 3LKRA 2FX7H 4KKQA 2DJMA 1T0RC 1AS7A 1J9QA 2V7NB 5CSBA 4IWQA 2FBJH 1Y6NR 4UIKH 5LAXB 3TZVC 2WQ6A 1F6LL 1H3PL 3MGBA 1NAMH 1TIFA 1TQVA 1XH3B 3L3HB 3VU2A 5E08L 4JFSA 4UT6L 4D0BB 4ATZD 2APXA 4X6DB 4BAXA 1IM9A 5AOLA 4I3SL 5T3XH 2XGSA 3NS8A 3FTYA 3EFDH 2AABH 1BPVA 1NUDA 1TO4A 3QQ9C 3ZTJH 5HBBA 3TFBA 3QULA 1T0MB 4KIKA 3CHPA 3O8XC 1JZFA 4ELME 3TG5A 4P07A 1MFUA 3RZCD 5E9DB 2WANA 3U4KA 3CHXA 2JQMA 4IOSA 2YD2A 1PTZA 2F6AA 4WO0A 1E8ZA 4IRSD 2CK0H 4H88L 1ZOYB 3NIFB 5GGQH 1P6AB 2Q7AA 3CVIL 4ALAC 4X9FA 1N70A 1FFQA 2XQYA 3VH8B 3EJCA 1ZVYA 3WNNA 3MX3A 4NQEB 4UQYA 4BGLA 3KHQA 4WSKA 1U8CA 3H4FA 4X0KB 5DMIL 1JZEA 3QG7H 1FWXA 1T1XA 2W9DL 3HTLX 5CU9A 1BYNA 4ZRIA 3L13A 1DCLA 2QZAA 4DPCX 3MBEB 2AXFA 5AZEL 1U4AA 3I9V1 2IBZX 1VFBB 3H7LA 4NAQA 5I19H 3MX0B 2XVKA 2X4SB 4Y5VA 5GS0H 4J4PA 2H3NA 4JFEB 3SPVB 3L9EA 4KMLB 1G84A 4HJ1A 3IGFA 4U63A 2K5PA 4OGAC 3K4DA 1Z5LA 4AEEA 2X2JA 2B1AH 2HH0L 4J0UA 4GSDL 1I8MB 4ZO6A 5T1DL 3IM1A 4XMUA 4FZEH 2R0WL 4Z7UE 4QKXB 1P4IH 5AUKA 5AAWA 4JVUA 2QADD 3QIWA 1C12B 3K9PB 3EFFB 1CQVA 4ATWA 3TEXA 3EO0A 4WV1C 2VLKA 2MP2B 3B5GA 3RWEB 5E8EA 2VL4A 3N42F 3AB0B 3HCVB 4NO5A 5ITFA 3STLB 2KHWB 5J1TC 4LNUD 2CIIA 4Z7WF 4I0PB 1YECL 3JWNH 2PXYB 2FEDD 1AWDA 2RMMA 2DBLH 1MLBB 2LJ5A 3CVLA 1DSYA 4IUMB 2FYYA 1IV8A 2PTUA 1IE4A 5IA7A 2DQGH 2NY5H 3RJDA 1KLGB 1JFQH 4HOUA 2R8SL 3S34L 1BEXA 4Z7UB 1CMOA 3MA5A 2ZOTA 4U6XA 3GSUB 3GSOB 4HBCL 5A2BA 1ONQA 4JUSA 4OD1H 3KWWB 4AEIH 5E6ID 1EDUA 3FZUC 2B0SH 3RP1A 2WXHA 4AGOA 5E8OA 1ZBPA 1R5IA 4PREA 5D7IF 1QX1A 4JY6B 2AJ3A 3T0AA 4U6HA 5BXUA 1HCFX 2CBOA 4ENEC 4ZSOB 1CLYH 2HWZL 3CDZB 4OGAD 2RD0A 4WFHD 5FUZL 4W4OC 2PXYD 2YS4A 3HE7A 3T6WA 3VM7A 4J8FA 1SMDA 4MZ2A 1JXFA 4KSLC 5D1ZI 4AQ8A 1SQ2N 2OXGA 1U91B 2VKWA 1RUAL 2A6DA 1LMIA 3KMDA 4ZS6D 3KWWA 4E74A 2CLRA 1X9LA 1GJZA 3IMRA 3OXGA 4JN2B 1PGBA 4KKLC 4WGKA 4YO0A 3W0WD 4R0LA 4JKWA 3WKNA 4UNVA 5CECB 3H0TA 4U3SB 4HHWA 2VXTL 2ZAIA 4DK5A 1YEHL 5CMYA 2P52A 4HYTB 3GUFA 3CHMA 1L5GB 4HK0A 1EERB 3BYYA 1ET6A 4PJIA 4Q4EA 2X9ZA 3WAPA 4WEUD 2CMRL 5AYTA 3QZLA 3N85L 1ZTXH 3PPSA 5I8KL 1KYUA 4XVTL 4AJYV 1ITBB 3PGFL 4HAGA 5JOPD 1MSPA 2XDHA 3BUQA 2OAAA 2CS4A 5E4EB 1TU2A 4XXDA 1WH3A 4XNUL 4EOWL 3NFNB 3WFEL 2XC8A 4R7LA 5FGSA 2Z64C 3CPLB 4CRWA 2LOEA 5B7EA 1CE1L 1QBLL 4I85A 2C7NB 1Q9OA 3VMOA 3D6GA 5BW7C 2KT6A 3BGFB 4G9FD 2D7NA 4GRLD 5KSUB 1Y56A 1HH6B 2WM0A 3DIDA 4OZIE 2FE0A 2BSRA 2Z93A 2Z91A 4ZUWB 5E6JA 2A6IA 1UGJA 3HI1B 2DMKA 2J2ZA 4HIJA 1HKLL 4QAMB 2GSIB 5DTFA 3AAZA 2X89D 3IGAA 2XKSA 5DMKA 4PWKA 5IR1A 2MYOA 2CFZA 4PJ9D 4OQ1A 3GMLA 1MPAH 1KPVB 4X8QA 2R0LH 2Z8WC 4PBWD 1Z9NA 1ZTMA 2X4NB 3IFOA 4R96A 5HI5C 1XLQA 4N2QA 5ANMA 3KYCD 1MREL 2H7WA 4ZPTB 1RM6C 4YHIB 1NCIA 2AVGA 4LBEB 3W2DA 2HYZA 5CEYA 3QIUB 3IJHA 1J8KA 5L8LB 2AWTA 3LEXA 5KYWA 4MEMA 3I6GA 3QI9D 5B1AB 4YPJA 5GXBB 2CR5A 2GSIA 3SKMB 4PJGE 1GJIA 2HRGA 3MRFA 3H42H 3EJZC 2XQBL 1N10A 4PJBF 3VWJC 4R5TA 5IIEB 4JLCA 1QRND 4PJ7F 1T0QC 3KVQA 1YO4A 3HKZA 2VH5H 5FECB 4RM9A 2XWXA 3A4AA 4K9EH 4U4BA 2EDWA 1TJFA 4HI8A 2HG5B 3OKNB 4PGBA 5TDPB 5C6WH 3V2OA 2EIZA 3EFDL 1A9BB 5HYJE 1HXYD 3SYPA 3GHEH 2PIAA 3MV7A 4W9IC 1MCRA 1MCQA 2EH7H 3T5WA 2HT4C 2KDGA 5J8OA 4HJTA 1DLHB 1GOHA 1NFAA 1NI2A 5IBUB 4ZMVA 2CXGA 3CN1A 1DVFC 4G9FE 4QRUB 3N1YC 5CBOA 3H6AA 3P0VL 6FABH 5I1DA 4BESA 3BJ91 3QA3A 4ISVA 5IB2A 4K3DL 1A6PA 3DOIA 3QISA 3DPDA 2KQMA 3MZTA 4Z7OB 5KWYC 2ZPYA 1QQDB 3BKMH 4B6ZA 5HHOE 4HULB 1F11A 4Z7AA 2WDRB 4L1BA 4XEIG 2A9NH 5GGTA 1XX9C 3LKSB 4IKLA