The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
26
|
sequence length |
114
|
structure length |
114
|
Chain Sequence |
LSPLSTHVLNAAQGVPGANMTIVLHRLDPVSSAWNILTTGITNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFYPYVEIVFTITNTSQHYHVPLLLSRFSYSTTRGS
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule keywords |
5-hydroxyisourate hydrolase
|
| publication title |
Probing the Evolution of Hydroxyisourate Hydrolase into Transthyretin through Active-Site Redesign
doi rcsb |
| source organism |
Danio rerio
|
| molecule tags |
Hydrolase
|
| total genus |
26
|
| structure length |
114
|
| sequence length |
114
|
| chains with identical sequence |
B, C, D, E, F, G, H
|
| ec nomenclature |
ec
3.5.2.17: Hydroxyisourate hydrolase. |
| pdb deposition date | 2009-09-03 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00576 | Transthyretin | HIUase/Transthyretin family |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Sandwich | Immunoglobulin-like | Transthyretin/hydroxyisourate hydrolase domain |
