The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
176
|
sequence length |
470
|
structure length |
470
|
Chain Sequence |
NVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQDVNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWRAEREAVVGLEAVSDSFSPMKVEKKSDGVTEIDDVLLIETQGETAQALAIRLARPVVVIDKMAGKVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQHHYGEERYRPCSLLRQRALLESGY
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule keywords |
Probable 3-hydroxybutyryl-CoA dehydrogenase
|
| publication title |
Crystal Structure of 3-Hydroxybutyryl-Coa Dehydrogenase from Escherichia Coli K12
rcsb |
| source organism |
Escherichia coli
|
| molecule tags |
Oxidoreductase
|
| total genus |
176
|
| structure length |
470
|
| sequence length |
470
|
| chains with identical sequence |
B, C
|
| ec nomenclature |
ec
1.1.1.157: 3-hydroxybutyryl-CoA dehydrogenase. |
| pdb deposition date | 2010-04-22 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00725 | 3HCDH | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain |
| A | PF02737 | 3HCDH_N | 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain |
| A | PF18321 | 3HCDH_RFF | 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | ||
| Alpha Beta | 2-Layer Sandwich | Transcription Regulator spoIIAA | Transcription Regulator spoIIAA | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain |
